UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
dna topoisomerase (440) 440
science & technology (358) 358
life sciences & biomedicine (269) 269
deoxyribonucleic acid--dna (216) 216
humans (211) 211
cancer (135) 135
dna damage (126) 126
oncology (111) 111
etoposide (106) 106
dna topoisomerases, type ii - metabolism (99) 99
cytotoxicity (98) 98
apoptosis (94) 94
dna (94) 94
animals (90) 90
proteins (89) 89
multidisciplinary sciences (87) 87
science & technology - other topics (87) 87
cell cycle (85) 85
enzymes (80) 80
gene expression (70) 70
chemotherapy (69) 69
medicine (69) 69
research article (68) 68
science (67) 67
antineoplastic agents - pharmacology (62) 62
biochemistry & molecular biology (61) 61
cell biology (56) 56
dna repair (56) 56
tumors (56) 56
cell line, tumor (55) 55
genomes (55) 55
pharmacology & pharmacy (55) 55
dna topoisomerases, type ii - genetics (54) 54
chromosomes (52) 52
female (52) 52
topoisomerase ii (52) 52
antitumor agents (48) 48
anticancer properties (47) 47
deoxyribonucleic acid (47) 47
drugs (47) 47
kinases (47) 47
cancer therapies (46) 46
genes (46) 46
male (46) 46
tumor cell lines (46) 46
doxorubicin (45) 45
breast cancer (44) 44
drug resistance (44) 44
topoisomerase ii inhibitors (44) 44
mice (43) 43
transcription (43) 43
topoisomerase ii inhibitors - pharmacology (42) 42
toxicity (42) 42
etoposide - pharmacology (41) 41
leukemia (41) 41
inhibitors (40) 40
mutation (40) 40
antitumor activity (39) 39
biology (38) 38
dna biosynthesis (36) 36
apoptosis - drug effects (35) 35
cell proliferation (35) 35
dna-binding proteins - metabolism (35) 35
genetic aspects (35) 35
phosphorylation (35) 35
research (35) 35
chromatin (34) 34
analysis (33) 33
tumor cells, cultured (32) 32
cell death (31) 31
cell division (31) 31
chemistry (31) 31
chemistry, medicinal (31) 31
biotechnology (30) 30
physical sciences (28) 28
inhibition (27) 27
biochemistry (26) 26
cell proliferation - drug effects (26) 26
drug development (26) 26
genomics (26) 26
replication (26) 26
toxicology (26) 26
anthracycline (25) 25
care and treatment (25) 25
p53 protein (25) 25
dna topoisomerases, type ii - chemistry (24) 24
dna-binding proteins - genetics (24) 24
flow cytometry (24) 24
genetics & heredity (24) 24
life sciences (24) 24
signal transduction (24) 24
genetics (23) 23
pharmacology (23) 23
polymerase chain reaction (23) 23
antigens, neoplasm - metabolism (22) 22
cell survival (22) 22
dna - metabolism (22) 22
dose-response relationship, drug (22) 22
health aspects (22) 22
medical research (22) 22
more...
Library Location Library Location
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Current medicinal chemistry, ISSN 0929-8673, 12/2010, Volume 17, Issue 35, pp. 4270 - 4290
Journal Article
Chemical research in toxicology, ISSN 0893-228X, 03/2016, Volume 29, Issue 3, pp. 415 - 420
Journal Article
Scientific reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 10344 - 14
DNA topoisomerase II (Topo II) is crucial for resolving topological problems of DNA and plays important roles in various cellular processes, such as replication, transcription, and chromosome segregation... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | DNA topoisomerase (ATP-hydrolysing) | Razoxane | Transcription | DNA damage | Homologous recombination | DNA topoisomerase | Double-strand break repair | Nuclei | DNA repair | Bleomycin | Immunofluorescence | Genetic recombination | Deoxyribonucleic acid--DNA | Photobleaching
Journal Article
Current topics in medicinal chemistry, ISSN 1568-0266, 01/2019, Volume 19, Issue 9, pp. 730 - 740
Inhibitors targeting human topoisomerase I and topoisomerase II alpha have provided a useful chemotherapy option for the treatment of many patients suffering from a variety of cancers... 
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Cell proliferation | Medical research | DNA topoisomerase (ATP-hydrolysing) | Immunomodulation | DNA topoisomerase | Clinical trials | DNA repair | Cancer therapies | Patients | Modulators | Side effects | Chemotherapy | Inhibitors | Immunotherapy | Deoxyribonucleic acid--DNA | Cancer
Journal Article
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 04/2010, Volume 5, Issue 4, pp. e10186 - e10186
Background: Topoisomerase II is critical for DNA replication, transcription and chromosome segregation and is a well validated target of anti-neoplastic drugs including the anthracyclines and epipodophyllotoxins... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Humans | Etoposide - pharmacology | Intercalating Agents | Quinolones - pharmacology | DNA - metabolism | Thiazoles - therapeutic use | Drug Delivery Systems | Quinolones - chemistry | DNA Topoisomerases, Type II - drug effects | Naphthyridines - therapeutic use | Cell Line, Tumor | G2 Phase | Antineoplastic Agents - pharmacology | Thiazoles - pharmacology | DNA Damage | DNA Fragmentation - drug effects | Naphthyridines - pharmacology | Apoptosis | Enzymes | Care and treatment | DNA replication | Anthracyclines | Oncology, Experimental | Etoposide | Research | Genetic transcription | Ovarian cancer | DNA | Genetic research | Genetic aspects | Drug therapy | Cancer | Drugs | Intercalating agents | Yeast | Ovarian carcinoma | Transcription | Toxicity | Leukemia | DNA damage | Clinical trials | Cytotoxicity | Drug delivery | Biochemistry | Structure-activity relationships | Intercalation | Drug resistance | Cancer therapies | Doxorubicin | Fragmentation | Analogs | Poisons | Platinum | Interrogation | DNA fragmentation | Cell cycle | Drug dosages | Deoxyribonucleic acid--DNA | Medical research | DNA topoisomerase (ATP-hydrolysing) | Prokaryotes | Myeloid leukemia | Medicine | DNA biosynthesis | Side effects | Anthracycline | Poisoning | Acute myeloid leukemia | Pharmaceuticals | Index Medicus | Deoxyribonucleic acid
Journal Article