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New England Journal of Medicine, ISSN 0028-4793, 05/2015, Volume 372, Issue 20, pp. 1887 - 1897
Journal Article
Molecular Therapy, ISSN 1525-0016, 03/2015, Volume 23, Issue 3, pp. 477 - 487
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2011, Volume 121, Issue 6, pp. 2160 - 2168
Journal Article
Gene Therapy, ISSN 0969-7128, 10/2011, Volume 18, Issue 10, pp. 996 - 1005
We use both large and small animal models in our pre-clinical evaluation of gene transfer agents (GTAs) for cystic fibrosis (CF) gene therapy. Here, we report... 
gene delivery | lung | non-viral | cystic fibrosis | sheep | aerosol | MEDICINE, RESEARCH & EXPERIMENTAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPLEXES | COMPACTED DNA NANOPARTICLES | CFTR GENE | THERAPY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PLASMID DNA | IN-VIVO | GENETICS & HEREDITY | MICE | OPTIMIZATION | ION-TRANSPORT DEFECT | EXPRESSION | Cystic Fibrosis - therapy | Gene Transfer Techniques | Polyethylene Glycols | DNA, Complementary - administration & dosage | Liposomes - administration & dosage | Humans | DNA, Complementary - genetics | Administration, Inhalation | Cystic Fibrosis Transmembrane Conductance Regulator - metabolism | RNA, Messenger - metabolism | Animals | Polyethyleneimine - administration & dosage | Cystic Fibrosis - genetics | Cystic Fibrosis Transmembrane Conductance Regulator - genetics | Sheep | Nanoparticles - administration & dosage | Genetic Therapy - methods | Cystic fibrosis | Genetic aspects | Research | Drug therapy | Gene expression | Gene therapy | Health aspects | Aerosols | Lungs | Index Medicus | Animal models | Epithelial cells | Lung | Clinical trials | mRNA | Respiratory tract | Cf gene | nanoparticles | Haptoglobin | Alveoli | Polyethylene | Gene transfer | Bronchus | Inflammation | Lysine | Plasmids | DNA | Neutrophilia | Conductance | Liposomes | Cystic fibrosis transmembrane conductance regulator | polyethyleneimine
Journal Article
Biomaterials, ISSN 0142-9612, 2015, Volume 77, pp. 14 - 25
Abstract Sunflower-type nanogels carrying the QD 655 nanoprobe can be used for both gene transfection and bioimaging of hMSCs. The entry of sunflower-type... 
Advanced Basic Science | Dentistry | Sunflower-type | Gene delivery | Bioimaging | Nanogel | MATERIALS SCIENCE, BIOMATERIALS | DRUG-DELIVERY | ENGINEERING, BIOMEDICAL | TRANSFECTION | PROLIFERATION | PLURIPOTENCY | SIRNA DELIVERY | CANCER | NANOPARTICLES | FLUORESCENCE | COPY NUMBER | EFFICIENCY | Microscopy - methods | DNA, Complementary - administration & dosage | Humans | Cell Tracking - methods | DNA, Complementary - genetics | Core Binding Factor Alpha 1 Subunit - analysis | Polyethyleneimine - toxicity | Mesenchymal Stromal Cells - cytology | Transfection | Drug Compounding | SOX9 Transcription Factor - analysis | Female | Quantum Dots - analysis | Genes, Reporter | Mesenchymal Stromal Cells - drug effects | CCAAT-Enhancer-Binding Protein-alpha - analysis | Gene Dosage | Polyethylene Glycols - toxicity | Static Electricity | Polyethylene Glycols - administration & dosage | Mesenchymal Stem Cell Transplantation - methods | Animals | Mice, Nude | Polyethyleneimine - administration & dosage | Poloxamer | CCAAT-Enhancer-Binding Protein-alpha - genetics | Mice | Mice, Inbred BALB C | Polymorphism, Single Nucleotide | Heparin | SOX9 Transcription Factor - genetics | Core Binding Factor Alpha 1 Subunit - genetics | Endosomes | Atomic force microscopy | Chemical properties | Genes | Stem cells | Index Medicus | Biomedical materials | Medical imaging | Effectiveness | Quantum dots | Nanostructure | Confocal
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 02/2011, Volume 186, Issue 4, pp. 2454 - 2461
Journal Article
Circulation, ISSN 0009-7322, 03/2002, Volume 105, Issue 10, pp. 1233 - 1239
Background-Although viral vector systems are efficient to transfect foreign genes into blood vessels, safety issues remain in relation to human gene therapy.... 
Restenosis | Gene therapy | Vessels | Ultrasonics | restenosis | CARDIAC & CARDIOVASCULAR SYSTEMS | HEPATOCYTE GROWTH-FACTOR | gene therapy | ultrasonics vessels | BALLOON CATHETER | LIPOSOME METHOD | HEMAGGLUTINATING VIRUS | THERAPY | IN-VIVO | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | TRANSCRIPTION FACTOR | INVIVO GENE-TRANSFER | SMOOTH-MUSCLE CELLS | Carotid Arteries - drug effects | Carotid Arteries - metabolism | Carotid Stenosis - prevention & control | Tumor Suppressor Protein p53 - biosynthesis | Muscle, Smooth, Vascular - metabolism | DNA, Complementary - administration & dosage | Humans | Luciferases - administration & dosage | Endothelium, Vascular - drug effects | Fluorocarbons - administration & dosage | Male | Tumor Suppressor Protein p53 - genetics | Feasibility Studies | Luciferases - genetics | Endothelium, Vascular - ultrastructure | Transfection - methods | Tumor Suppressor Protein p53 - administration & dosage | Genes, Reporter | Muscle, Smooth, Vascular - drug effects | Gene Transfer Techniques | Gene Expression | Catheterization | Muscle, Smooth, Vascular - ultrastructure | Cells, Cultured | Rats | Albumins - administration & dosage | Carotid Stenosis - pathology | Rats, Sprague-Dawley | Animals | Endothelium, Vascular - metabolism | Plasmids | Carotid Arteries - pathology | Luciferases - biosynthesis | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Nanomedicine: Nanotechnology, Biology, and Medicine, ISSN 1549-9634, 2015, Volume 12, Issue 3, pp. 811 - 821
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 05/2015, Volume 372, Issue 20, pp. 1954 - 1955
Journal Article