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Molecular cell, ISSN 1097-2765, 2017, Volume 67, Issue 4, pp. 608 - 621.e6
Transcription is a source of genetic instability that can notably result from the formation of genotoxic DNA:RNA hybrids, or R-loops, between the nascent mRNA... 
genetic instability | intron | recombination | mRNA splicing | transcription | mRNP | R-loops | messenger ribonucleoparticle | ELONGATION IMPAIRMENT | YEAST | MESSENGER-RNA | CANDIDA-GLABRATA | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLOBAL ANALYSIS | R-LOOP FORMATION | SACCHAROMYCES-CEREVISIAE | EXPRESSION | SCHIZOSACCHAROMYCES-POMBE | REVEALS | CELL BIOLOGY | Genomic Instability | Nucleic Acid Heteroduplexes - genetics | DNA, Fungal - genetics | Spliceosomes - genetics | Saccharomyces cerevisiae - genetics | Humans | Cryptococcus neoformans - genetics | Databases, Genetic | DNA, Fungal - chemistry | Structure-Activity Relationship | Nucleic Acid Heteroduplexes - metabolism | Saccharomyces cerevisiae - metabolism | Schizosaccharomyces - genetics | Spliceosomes - metabolism | RNA Splicing | Ribonucleoproteins - genetics | Transcription, Genetic | RNA, Fungal - genetics | Nucleic Acid Conformation | Gene Expression Regulation, Fungal | Cell Line | Introns | RNA, Fungal - chemistry | Computational Biology | Genotype | Ribonucleoproteins - metabolism | Fungal Proteins - genetics | Candida glabrata - metabolism | Cryptococcus neoformans - metabolism | Nucleic Acid Heteroduplexes - chemistry | RNA, Fungal - metabolism | Schizosaccharomyces - metabolism | Phenotype | DNA, Fungal - metabolism | DNA Damage | Candida glabrata - genetics | Fungal Proteins - metabolism | RNA | Analysis | Genes | Genomics | Genetic research | Genetic aspects | Genetic transcription | Anopheles | Messenger RNA | Cryptococcus neoformans | Life Sciences | RNA, Fungal | Spliceosomes | Schizosaccharomyces | Biochemistry, Molecular Biology | Ribonucleoproteins | Fungal Proteins | Candida glabrata | DNA, Fungal | Nucleic Acid Heteroduplexes | Molecular biology | Saccharomyces cerevisiae
Journal Article
Natural product reports, ISSN 0265-0568, 2014, Volume 31, Issue 10, pp. 1449 - 1473
Covering: 1965–2014Fungi (Ascomycota and Basidiomycota) are prolific producers of structurally diverse terpenoid compounds. Classes of terpenoids identified in... 
Journal Article
Nature (London), ISSN 1476-4687, 2016, Volume 530, Issue 7591, pp. 485 - 489
Eukaryotic transcription activators stimulate the expression of specific sets of target genes through recruitment of co-activators such as the RNA polymerase... 
PROTEIN | CANDIDA-GLABRATA | PDR1 | MULTIDISCIPLINARY SCIENCES | Fluconazole - pharmacology | Mediator Complex - metabolism | Transcriptional Activation - drug effects | Thiourea - pharmacology | Candidiasis - microbiology | Trans-Activators - chemistry | Ketoconazole - pharmacology | DNA-Binding Proteins - metabolism | Gene Expression Regulation, Fungal - drug effects | Mediator Complex - chemistry | Drug Resistance, Multiple, Fungal - drug effects | Candidiasis - drug therapy | Protein Binding - drug effects | Nuclear Magnetic Resonance, Biomolecular | Binding Sites - drug effects | Antifungal Agents - pharmacology | Protein Structure, Tertiary | Hydrazines - pharmacology | Drug Resistance, Fungal - drug effects | Hydrazines - pharmacokinetics | Models, Molecular | Thiourea - pharmacokinetics | Saccharomyces cerevisiae Proteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Candida glabrata - metabolism | Transcription Factors - metabolism | Up-Regulation - drug effects | Animals | Saccharomyces cerevisiae Proteins - metabolism | Trans-Activators - metabolism | Mice | Candida glabrata - genetics | Thiourea - analogs & derivatives | Candida glabrata - drug effects | Fungal Proteins - metabolism | Saccharomyces cerevisiae Proteins - chemistry | Prevention | Drug resistance in microorganisms | Gene mutations | Yeast fungi | Physiological aspects | Genetic aspects | Research | Fungi | Transcription factors | Genes | Mutation | Fungal infections | RNA polymerase | Drug resistance | Urogenital system
Journal Article
Journal of Natural Products, ISSN 0163-3864, 03/2017, Volume 80, Issue 3, pp. 756 - 770
..., industrial, and pharmaceutical applications. Despite their importance in natural products chemistry, identification of fungi remains a daunting task for chemists, especially those who do not work with a trained mycologist... 
RNA-POLYMERASE-II | CHEMISTRY, MEDICINAL | RDNA REGION | INTERNAL TRANSCRIBED SPACER | PLANT SCIENCES | PLANT-PATHOGENIC FUNGI | LARGE-SUBUNIT | KINGDOM FUNGI | EVOLUTION | PHYLOGENETIC-RELATIONSHIPS | SEQUENCE ALIGNMENT | RIBOSOMAL DNA | PHARMACOLOGY & PHARMACY | DNA - genetics | Biological Products - chemistry | DNA - chemistry | Molecular Structure | Fungi - chemistry | Phylogeny | Research | Review
Journal Article
BMC microbiology, ISSN 1471-2180, 2009, Volume 9, Issue 1, pp. 177 - 177
.... Thus, there is a real need to discover new targets for therapy. Particular attention has been paid to the biochemical composition and organisation of the fungal cell wall, because it mediates the host-fungus interplay... 
EXTRACELLULAR-MATRIX PROTEINS | ADHESION | GENE | BIOSYNTHESIS | SUSCEPTIBILITY | MICROBIOLOGY | FUNGAL MELANINS | SURFACE HYDROPHOBICITY | FONSECAEA-PEDROSOI | VIRULENCE | BINDING | Aspergillus fumigatus - ultrastructure | Microscopy, Electron, Scanning | DNA, Fungal - genetics | Cell Wall - chemistry | Fungal Proteins - genetics | Aspergillus fumigatus - genetics | Aspergillus fumigatus - pathogenicity | Sequence Analysis, DNA | Melanins - biosynthesis | Flow Cytometry | Virulence - genetics | Spores, Fungal - ultrastructure | Aspergillosis - microbiology | Cell Wall - ultrastructure | Spores, Fungal - genetics | Fungal Proteins - metabolism | Aspergillus | Aspergillosis | Causes of | Physiological aspects | Bacterial cell walls | Research | Drug therapy | Health aspects | Melanin | Biosynthesis | Mutation | Microbiology | Microscopy | Pathogenesis | Public health | Drugs | Flow cytometry | Adhesins | Prognosis | Insertion | Hydrophobicity | Gene deletion | Cell surface | Fibronectin | Laminin | Missense mutation | Heads | hydrophobins | Scanning electron microscopy | Cell walls | Colonies | atomic force microscopy | virulence factors | Infection | Point mutation | Immunocompromised hosts | ALB1 gene | Conidia | Virulence | Melanins | Fungal Proteins | DNA, Fungal | Cell Wall | Life Sciences | Microbiology and Parasitology | Spores, Fungal | Aspergillus fumigatus
Journal Article