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Immunity, ISSN 1074-7613, 03/2013, Volume 38, Issue 3, pp. 514 - 527
Interleukin-21 (IL-21) has broad actions on T and B cells, but its actions in innate immunity are poorly understood. Here we show that IL-21 induced apoptosis... 
NKT CELLS | HOMEOSTASIS | FOLLICULAR-HELPER-CELLS | HUMAN B-CELLS | STEADY-STATE | INTERLEUKIN-21 | DIFFERENTIATION | IMMUNOLOGY | IMMUNE TOLERANCE | T-CELLS | NEGATIVE REGULATOR | Natural Killer T-Cells - drug effects | Oligonucleotide Array Sequence Analysis | Apoptosis - drug effects | Dendritic Cells - immunology | STAT5 Transcription Factor - immunology | Receptors, Interleukin-21 - genetics | Interferon-gamma - metabolism | CD4-Positive T-Lymphocytes - immunology | Interleukins - genetics | Gene Expression - immunology | STAT3 Transcription Factor - genetics | Apoptosis Regulatory Proteins - immunology | DNA-Binding Proteins - immunology | Membrane Proteins - genetics | CD4-Positive T-Lymphocytes - metabolism | Mice, Transgenic | DNA, Intergenic - genetics | Protein Binding - immunology | Blotting, Western | Apoptosis Regulatory Proteins - metabolism | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Mice, Knockout | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Galactosylceramides - immunology | Mice | STAT3 Transcription Factor - immunology | Gene Expression - drug effects | Galactosylceramides - pharmacology | DNA-Binding Proteins - deficiency | STAT5 Transcription Factor - genetics | STAT5 Transcription Factor - metabolism | Receptors, Interleukin-21 - deficiency | Flow Cytometry | Bcl-2-Like Protein 11 | Natural Killer T-Cells - metabolism | DNA, Intergenic - metabolism | Interleukins - immunology | Proto-Oncogene Proteins - immunology | Apoptosis Regulatory Proteins - genetics | Dendritic Cells - drug effects | Membrane Proteins - metabolism | Interleukins - pharmacology | Dendritic Cells - metabolism | STAT3 Transcription Factor - metabolism | Proto-Oncogene Proteins - metabolism | Receptors, Interleukin-21 - immunology | Mice, Inbred C57BL | Cells, Cultured | Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology | Membrane Proteins - immunology | Proto-Oncogene Proteins - genetics | DNA-Binding Proteins - genetics | Animals | Apoptosis - immunology | Interferon-gamma - immunology | CD4-Positive T-Lymphocytes - drug effects | DNA, Intergenic - immunology | Natural Killer T-Cells - immunology | Interleukins | Dendritic cells | Analysis | Genomics | Macrophage colony stimulating factor | Biological response modifiers | T cells | Apoptosis | Cytokines | Genes | Genomes | Kinases | Binding sites | Deoxyribonucleic acid--DNA | apoptosis | dendritic cells | GM-CSF | IL-21
Journal Article
Molecular Cell, ISSN 1097-2765, 01/2017, Volume 65, Issue 1, pp. 168 - 175
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2018, Volume 13, Issue 9, p. e0204168
Background Antigen presentation on monocyte surface to T-cells by Major Histocompatibility Complex, Class II (MHC-II) molecules is fundamental for pathogen... 
CELLS | CIITA | HLA-DR | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | SEPTIC SHOCK | DR EXPRESSION | MULTIPLE ORGAN FAILURE | CTCF | CD14 | CHROMATIN ARCHITECTURE | Humans | CCCTC-Binding Factor - genetics | Receptors, IgG - deficiency | Male | Monocytes - immunology | Genetic Loci | Case-Control Studies | Receptors, IgG - genetics | Sepsis - pathology | Antigen Presentation | GPI-Linked Proteins - deficiency | Base Sequence | Chromatin - immunology | Monocytes - pathology | Trans-Activators - genetics | Adult | Female | Transcription, Genetic | CCCTC-Binding Factor - immunology | T-Lymphocytes - pathology | Nuclear Proteins - genetics | Trans-Activators - immunology | Chromatin - chemistry | Sepsis - immunology | GPI-Linked Proteins - immunology | Signal Transduction | Gene Expression Regulation | Lipopolysaccharide Receptors - immunology | Receptors, IgG - immunology | DNA, Intergenic - genetics | Nuclear Proteins - immunology | Sepsis - genetics | Histocompatibility Antigens Class II - immunology | Regulatory Elements, Transcriptional | Lipopolysaccharide Receptors - genetics | Protein Binding | T-Lymphocytes - immunology | Histocompatibility Antigens Class II - genetics | Immunocompromised Host | DNA, Intergenic - immunology | GPI-Linked Proteins - genetics | Flow cytometry | Chromatin | Intensive care | Immunoprecipitation | Genes | Critical care | Lymphocytes T | Genomes | Regulatory sequences | Gender | CD14 antigen | Blood | Gene sequencing | Proteins | Immunology | DNA-binding protein | Deoxyribonucleic acid--DNA | Enzyme-linked immunosorbent assay | Antigen presentation | Cytokines | Inflammation | Gene expression | Ribonucleic acid--RNA | Patients | Loci | CIITA protein | Immunosuppression | CD16 antigen | Monocytes | Hospitals | Major histocompatibility complex | Epigenetics | Sepsis | Histocompatibility antigen HLA | Anesthesiology | Histocompatibility | Binding sites | RNA | Deoxyribonucleic acid | Ribonucleic acid | DNA
Journal Article
The Journal of Immunology, ISSN 0022-1767, 05/2001, Volume 166, Issue 9, pp. 5366 - 5373
Journal Article
The Journal of Immunology, ISSN 0022-1767, 12/2003, Volume 171, Issue 12, pp. 6672 - 6679
Chromatin immunoprecipitations in naive CD4, but not CD8, T cells, demonstrated association of the IL-4 promoter with acetylated histone. Histone modifications... 
LEISHMANIA-MAJOR | DNA-BINDING | IKAROS | IN-VIVO | TRANSCRIPTION | CYTOKINE GENES | MICE | COORDINATE REGULATOR | DIFFERENTIATION | IMMUNOLOGY | HISTONE ACETYLATION | Chromatin - metabolism | Conserved Sequence - genetics | Immunity, Innate - genetics | Molecular Sequence Data | Th2 Cells - immunology | Leishmaniasis, Cutaneous - immunology | CD4-Positive T-Lymphocytes - immunology | Interleukin-4 - biosynthesis | Lymphocyte Activation - genetics | Heterochromatin - metabolism | T-Lymphocytes, Helper-Inducer - immunology | Base Sequence | Mast Cells - metabolism | Female | Conserved Sequence - immunology | Interleukin-4 - genetics | Cytokines - genetics | Leishmaniasis, Cutaneous - genetics | DNA-Binding Proteins | Cell Line | Mast Cells - immunology | Genetic Predisposition to Disease | T-Lymphocytes, Helper-Inducer - metabolism | Cytokines - metabolism | Interleukin-4 - metabolism | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Binding Sites - genetics | Genetic Markers | Transcription Factors - genetics | Ikaros Transcription Factor | Th2 Cells - metabolism | Mice, Knockout | Transcription Factors - metabolism | Animals | Enhancer Elements, Genetic | Mice | Mice, Inbred BALB C | Histones - metabolism | DNA, Intergenic - immunology | METHYLATION | CHROMATIN | BASIC BIOLOGICAL SCIENCES | 60 APPLIED LIFE SCIENCES | HISTONES | MODIFICATIONS | LYMPHOKINES | PROMOTERS | GENES | HETEROCHROMATIN | POLARIZATION
Journal Article
The Journal of Immunology, ISSN 0022-1767, 06/2003, Volume 170, Issue 12, pp. 6048 - 6056
Journal Article
Microbiology and Immunology, ISSN 0385-5600, 10/2002, Volume 46, Issue 10, pp. 677 - 683
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2012, Volume 287, Issue 30, pp. 25049 - 25059
Journal Article
PLoS Pathogens, ISSN 1553-7366, 2019, Volume 15, Issue 1, p. e1007534
Journal Article