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Journal of neurochemistry, ISSN 0022-3042, 2012, Volume 120, Issue 3, pp. 419 - 429
J. Neurochem. (2012) 120, 419–429. Mitochondrial dysfunction is a prominent feature of Alzheimer’s disease (AD) brain... 
mitochondrial transcription factor A | nuclear respiratory factors | proliferator‐activated receptor gamma coactivator 1α | Alzheimer’s disease | mitochondrial biogenesis | proliferator-activated receptor gamma coactivator 1α | Alzheimer's disease | proliferator-activated receptor gamma coactivator 1a | ACTIVATION | PROTEIN | OXIDATIVE DAMAGE | PGC-1-ALPHA | BIOCHEMISTRY & MOLECULAR BIOLOGY | AXONAL-TRANSPORT | NEUROSCIENCES | AMYLOID-BETA | COACTIVATOR PGC-1 | MOUSE MODEL | A-BETA | EXPRESSION | Humans | Middle Aged | Male | Mitochondrial Proteins - genetics | Nuclear Respiratory Factors - metabolism | Alzheimer Disease - pathology | Electron Transport Complex IV - metabolism | Dose-Response Relationship, Drug | CREB-Binding Protein - metabolism | Organelle Biogenesis | Transfection - methods | Mitochondrial Proteins - metabolism | Adenosine Triphosphate - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Amyloid beta-Protein Precursor - metabolism | Aged, 80 and over | Female | Hippocampus - ultrastructure | RNA Interference - physiology | Neuroblastoma - pathology | Alzheimer Disease - physiopathology | DNA, Mitochondrial - metabolism | Heat-Shock Proteins - metabolism | Enzyme Inhibitors - pharmacology | Gene Expression Regulation - physiology | Mitochondria - metabolism | Gene Expression Regulation - drug effects | Transcription Factors - metabolism | Neuroblastoma - ultrastructure | Cell Line, Tumor | Trans-Activators - metabolism | Aged | Cytochrome c | Neurosciences | Neurons | Amyloid beta-protein | Cytochrome oxidase | Mitochondrial DNA | Disease susceptibility | Biosynthesis | Neurochemistry | Mitochondria | Cellular biology | Alzheimers disease | Molecular biology | mitochondrial transcription factor A (TFAM) | nuclear respiratory factors (NRF) | proliferator-activated receptor gamma coactivator 1alpha (PGC-1a)
Journal Article
Journal Article
Journal Article
Blood, ISSN 1528-0020, 2012, Volume 119, Issue 6, pp. 1490 - 1500
.... Here, we show that ATM loss also leads to intrinsic mitochondrial abnormalities in thymocytes, including elevated reactive oxygen species, increased aberrant mitochondria, high cellular respiratory... 
OXIDATIVE STRESS | AUTOPHAGY GENE | BECLIN-1 | HEMATOPOIETIC STEM-CELLS | TUMOR-SUPPRESSOR | DJ-1 | IONIZING-RADIATION | HEMATOLOGY | CANCER | ATM-DEFICIENT MICE | PARKINSONS-DISEASE | Reactive Oxygen Species - metabolism | Thymocytes - metabolism | Humans | Immunoblotting | Autophagy | Lymphoma, T-Cell - metabolism | DNA-Binding Proteins - metabolism | Mitochondria - genetics | RNA Interference | Adenosine Triphosphate - metabolism | Tumor Suppressor Proteins - genetics | Membrane Potential, Mitochondrial | Apoptosis Regulatory Proteins - genetics | Cell Cycle Proteins - genetics | Membrane Proteins - metabolism | Protein-Serine-Threonine Kinases - metabolism | Fibroblasts - metabolism | Ataxia Telangiectasia - physiopathology | Beclin-1 | Microscopy, Electron, Transmission | Thymocytes - ultrastructure | Gene Expression | Tumor Suppressor Proteins - metabolism | Membrane Proteins - genetics | Mice, Inbred C57BL | Cell Cycle Proteins - metabolism | Cells, Cultured | Kaplan-Meier Estimate | Oxygen Consumption | Protein-Serine-Threonine Kinases - genetics | Ataxia Telangiectasia - metabolism | Mitochondria - metabolism | Ataxia Telangiectasia Mutated Proteins | DNA-Binding Proteins - genetics | Lymphoma, T-Cell - genetics | Reverse Transcriptase Polymerase Chain Reaction | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Animals | Ataxia Telangiectasia - genetics | Fibroblasts - cytology | Mice | Mitochondria - physiology | Lymphoid Neoplasia
Journal Article