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Nucleic Acids Research, ISSN 0305-1048, 09/2017, Volume 45, Issue 15, pp. e139 - e139
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 508, Issue 7495, pp. 222 - 227
Activated RAS GTPase signalling is a critical driver of oncogenic transformation and malignant disease. Cellular models of RAS-dependent cancers have been used... 
CELL LUNG-CANCER | RAS-TRANSFORMATION | OVEREXPRESSION | OXIDATIVE STRESS | HMTH1 | MESSENGER-RNA | GENE | MULTIDISCIPLINARY SCIENCES | HUMAN MUTT HOMOLOG | TUMORIGENESIS | SMALL-MOLECULE INHIBITION | ras Proteins - genetics | Colonic Neoplasms - genetics | Proto-Oncogene Proteins p21(ras) | Pyridines - chemistry | Colonic Neoplasms - drug therapy | Humans | Substrate Specificity | DNA Breaks, Single-Stranded - drug effects | Protein Kinase Inhibitors - chemistry | Pyrazoles - chemistry | Phosphoric Monoester Hydrolases - biosynthesis | DNA Repair Enzymes - metabolism | Female | Antineoplastic Agents - pharmacology | DNA Repair Enzymes - antagonists & inhibitors | Homeostasis - drug effects | Aminoquinolines - pharmacology | DNA Repair Enzymes - chemistry | Disease Models, Animal | Phosphoric Monoester Hydrolases - antagonists & inhibitors | Pyrazoles - pharmacology | Crystallization | Models, Molecular | Proto-Oncogene Proteins - genetics | Antineoplastic Agents - chemistry | Mice, SCID | Nucleotides - metabolism | Xenograft Model Antitumor Assays | Animals | Colonic Neoplasms - pathology | DNA Repair | DNA Repair Enzymes - biosynthesis | Proteomics | Protein Conformation | Mice | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Phosphoric Monoester Hydrolases - metabolism | Phosphoric Monoester Hydrolases - chemistry | Crizotinib | Enzymes | Colon cancer | Physiological aspects | Genetic aspects | Research | Nucleotides | Studies | Oxidative stress | Inhibitor drugs | Medical prognosis | Homeostasis | Mutation | Kinases | Experiments | Cancer | Index Medicus | Life Sciences | crizotinib | cancer | stereoselectivity | MTH1 | DNA repair | drug
Journal Article
Small, ISSN 1613-6810, 11/2014, Volume 10, Issue 21, pp. 4332 - 4339
Journal Article
Journal Article
ACS Nano, ISSN 1936-0851, 03/2014, Volume 8, Issue 3, pp. 2118 - 2133
The likelihood of intentional and unintentional engineered nanoparticle (ENP) exposure has dramatically increased due to the use of nanoenabled products.... 
genotoxicity | CometChip | engineered nanoparticles | DNA damage | comet | nanotoxicology | Index Medicus | Screening | Silver | Deoxyribonucleic acid | Zinc oxide | Exposure | Nanostructure | Assaying | Damage | Silicon dioxide
Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 09/2014, Volume 84, pp. 343 - 363
Fourteen new organotin(IV) complexes with general formula R SnL or R SnL where R = CH , C H , C H , C H , C H , CH –C H , C(CH ) , C H and... 
Organotin(IV) compound | Antitumor activity | Cytotoxicity | Antimicrobial activity | DNA interaction | Antileishmanial activity | CHEMISTRY, MEDICINAL | ACID | MOLECULAR-STRUCTURE | ANTITUMOR-ACTIVITY | DISK DIFFUSION | NMR | SPECTROSCOPIC CHARACTERIZATION | X-RAY STRUCTURES | BIOLOGICAL SCREENINGS | DERIVATIVES | CALF THYMUS DNA | Organotin Compounds - chemistry | Parasitic Sensitivity Tests | Humans | Bacteria - drug effects | Crystallography, X-Ray | Antifungal Agents - chemical synthesis | Antifungal Agents - chemistry | Structure-Activity Relationship | Dose-Response Relationship, Drug | Microbial Sensitivity Tests | Organotin Compounds - chemical synthesis | Anti-Bacterial Agents - chemistry | Leishmania - drug effects | Antiprotozoal Agents - chemical synthesis | Molecular Structure | Antifungal Agents - pharmacology | Fungi - drug effects | Organotin Compounds - pharmacology | Models, Molecular | Antiprotozoal Agents - chemistry | Antiprotozoal Agents - pharmacology | Solanum tuberosum - microbiology | DNA, Single-Stranded - chemistry | Solanum tuberosum - drug effects | Anti-Bacterial Agents - chemical synthesis | Artemia - drug effects | Animals | DNA, Single-Stranded - drug effects | Plasmids | Ligands | Anti-Bacterial Agents - pharmacology | Plant Tumors - microbiology | Tin compounds | Amphotericin B | Analysis | Spectrum analysis | DNA | Genetic research | Antiparasitic agents | Chemical properties | Mass spectrometry | Index Medicus
Journal Article