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Nature, ISSN 0028-0836, 2014, Volume 512, Issue 1, pp. 49 - 53
Journal Article
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 08/2014, Volume 16, Issue 8, pp. 711 - 718
Aims: This work explored the effects of irisin on metabolism, gene expression and mitochondrial content in cultured myocytes. Methods: C2C12 myocytes were... 
FNDC5 | | UCP3 | III | domain containing protein 5 | myokine | mitochondrial uncoupling protein 3 | PGC | fibronectin type | peroxisome proliferator‐activated receptor γ coactivator‐1α | Myokine | Fibronectin type III domain containing protein 5 (FNDC5) | Peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) | Mitochondrial uncoupling protein 3 (UCP3) | peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1 alpha) | fibronectin type III domain containing protein 5 (FNDC5) | CELLS | COACTIVATOR | MITOCHONDRIAL BIOGENESIS | TISSUE | NUCLEAR RESPIRATORY FACTORS | OBESITY | NRF-1 | ENDOCRINOLOGY & METABOLISM | PGC-1 | FAT | mitochondrial uncoupling protein 3 (UCP3) | Humans | Mitochondria, Muscle - metabolism | Muscle Fibers, Skeletal - drug effects | Muscle Fibers, Skeletal - metabolism | Glycolysis - drug effects | Nuclear Respiratory Factor 1 - genetics | DNA-Binding Proteins - metabolism | Oxidative Phosphorylation - drug effects | DNA-Binding Proteins - agonists | Nuclear Respiratory Factor 1 - agonists | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | High Mobility Group Proteins - agonists | Muscle Proteins - metabolism | Nuclear Respiratory Factor 1 - metabolism | Fibronectins - agonists | Cell Line | Cell Survival - drug effects | Fibronectins - pharmacology | High Mobility Group Proteins - metabolism | Recombinant Proteins - pharmacology | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Fibronectins - metabolism | Gene Expression Regulation - drug effects | Muscle Proteins - genetics | Transcription Factors - metabolism | Muscle Proteins - agonists | Mitochondrial Turnover - drug effects | Animals | Muscle Fibers, Skeletal - cytology | Cell Proliferation - drug effects | Fibronectins - genetics | Mice | Mitochondria, Muscle - drug effects | Kinetics | Transcription Factors - agonists | High Mobility Group Proteins - genetics | Fibronectins | Glucose metabolism | Muscles | Biosynthesis | Chemical properties | Glucose | Gene expression | Dextrose | Protein binding | Medical research | Metabolism | Rodents
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 09/2008, Volume 4, Issue 9, pp. 548 - 556
Journal Article
Immunity, ISSN 1074-7613, 08/2009, Volume 31, Issue 2, pp. 245 - 258
Effective clearance of apoptotic cells by macrophages is essential for immune homeostasis. The transcriptional pathways that allow macrophages to sense and... 
MOLIMMUNO | CELLIMMUNO | SIGNALING PATHWAYS | IN-VITRO | PHAGOCYTOSIS | PHOSPHATIDYLSERINE RECEPTOR | LIPID-METABOLISM | MER TYROSINE KINASE | CHOLESTEROL EFFLUX | TAM RECEPTORS | IMMUNOLOGY | LIVER-X-RECEPTORS | MICE LACKING | Spleen - immunology | Receptor Protein-Tyrosine Kinases - immunology | Signal Transduction - immunology | Receptors, Cytoplasmic and Nuclear - immunology | DNA-Binding Proteins - agonists | Autoimmunity - immunology | Immune Tolerance - immunology | Liver X Receptors | c-Mer Tyrosine Kinase | Proto-Oncogene Proteins - immunology | Orphan Nuclear Receptors | Autoimmune Diseases - metabolism | Autoimmune Diseases - pathology | Macrophages - immunology | Proto-Oncogene Proteins - metabolism | DNA-Binding Proteins - immunology | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Mice, Inbred C57BL | Autoimmune Diseases - immunology | Phagocytosis - immunology | Receptors, Cytoplasmic and Nuclear - agonists | Receptors, Cytoplasmic and Nuclear - genetics | Spleen - cytology | Macrophages - cytology | DNA-Binding Proteins - genetics | Receptor Protein-Tyrosine Kinases - metabolism | Mice, Knockout | Animals | Apoptosis - immunology | Spleen - metabolism | Mice | Tyrosine | Autoimmunity | Autoantibodies | Analysis | Development and progression | Macrophages | Apoptosis | Studies | Flow cytometry | Statistical analysis | Rodents | Software | Gene expression | Variance analysis | Cholesterol | Immune system
Journal Article
Journal Article
The Journal of Biological Chemistry, ISSN 0021-9258, 2016, Volume 291, Issue 3, pp. 1137 - 1147
Plant nucleotide-binding leucine-rich repeat (NLR) proteins enable plants to recognise and respond to pathogen attack. Previously, we demonstrated that the Rx1... 
NUCLEAR ACCUMULATION | NB-ARC DOMAIN | RESISTANCE PROTEIN | ATPASE ACTIVITY | REPLICATION ORIGIN RECOGNITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-PRODUCTS | RESONANCE ENERGY-TRANSFER | DISEASE-RESISTANCE | DEFENSE REGULATORS | PROTEIN-STRUCTURE PREDICTION | Plant Immunity | Lycopersicon esculentum - enzymology | DNA-Binding Proteins - metabolism | Plant Proteins - agonists | DNA-Binding Proteins - agonists | Plant Proteins - chemistry | Adenosine Triphosphate - metabolism | Electrophoretic Mobility Shift Assay | Plant Proteins - metabolism | Protein Interaction Domains and Motifs | Binding Sites | Peptide Fragments - genetics | Lycopersicon esculentum - immunology | Nucleotide Transport Proteins - chemistry | RNA - metabolism | Recombinant Proteins - metabolism | Lycopersicon esculentum - metabolism | Peptide Fragments - metabolism | DNA, Single-Stranded - metabolism | Adenosine Triphosphatases - metabolism | Models, Molecular | Recombinant Proteins - chemistry | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | Nucleotide Transport Proteins - agonists | Nucleotide Transport Proteins - metabolism | Hydrolysis | Proteins - genetics | Plant Proteins - genetics | Peptide Fragments - chemistry | Proteins - agonists | Proteins - metabolism | Adenosine Triphosphatases - chemistry | Nucleotide Transport Proteins - genetics | Adenosine Triphosphatases - genetics | Adenosine Diphosphate - metabolism | Mutation | Proteins - chemistry | Amino Acid Substitution | cellular immune response | Plant Biology | plant biochemistry | Nod-like receptor (NLR) | nucleotide | DNA binding protein | ATPases associated with diverse cellular activities (AAA)
Journal Article
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 2009, Volume 50, Issue 2, pp. 312 - 326
Liver X receptors (LXRs) are important regulators of cholesterol and lipid metabolism. LXR agonists have been shown to limit the cellular cholesterol content... 
Liver X receptor | Atherogenesis | Gene expression | ABC transporter | Cholesterol catabolism | atherogenesis | CELLULAR CHOLESTEROL | DIETARY-CHOLESTEROL | BIOCHEMISTRY & MOLECULAR BIOLOGY | ELEMENT-BINDING PROTEIN | X-RECEPTOR | PLASMA HDL CHOLESTEROL | cholesterol catabolism | NUCLEAR RECEPTOR LXR | OXYSTEROL RECEPTORS | GENE-EXPRESSION | LIGAND | liver X receptor | TRANSCRIPTION FACTOR | gene expression | Male | Fatty Liver - chemically induced | RNA, Messenger - metabolism | Apolipoproteins E - metabolism | DNA-Binding Proteins - metabolism | ATP-Binding Cassette Transporters - genetics | DNA-Binding Proteins - agonists | Time Factors | Liver X Receptors | ATP-Binding Cassette Transporters - metabolism | Female | Orphan Nuclear Receptors | ATP Binding Cassette Transporter 1 | Cholic Acids - therapeutic use | Foam Cells - metabolism | Sterol Regulatory Element Binding Protein 1 - metabolism | Atherosclerosis - pathology | Atherosclerosis - drug therapy | Mice, Inbred C57BL | Mice, Transgenic | Receptors, Cytoplasmic and Nuclear - agonists | Receptors, Cytoplasmic and Nuclear - genetics | DNA-Binding Proteins - genetics | Hypertriglyceridemia - chemically induced | Macrophages - metabolism | Animals | Sterol Regulatory Element Binding Protein 1 - genetics | Apolipoproteins E - genetics | Mice | Receptors, Cytoplasmic and Nuclear - metabolism | Index Medicus
Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 10/2007, Volume 28, Issue 1, pp. 91 - 106
Journal Article