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Science (American Association for the Advancement of Science), ISSN 0036-8075, 2012, Volume 336, Issue 6079, pp. 315 - 319
.... Our efforts to understand why DinB (DNA polymerase IV) overproduction is cytotoxic to Escherichia coli led to the unexpected insight that oxidation of guanine to 8-oxo... 
RESEARCH ARTICLE | Antibiotics | Cell death | DNA | Fluorescence | Cytotoxicity | Oxidation | Nucleotides | Overproduction | Genetic mutation | Guanine nucleotides | MUTAGENESIS | PROTEIN | REPLICATION | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | DOUBLE-STRAND BREAKS | HYDROGEN-PEROXIDE | MECHANISMS | MUTT-TYPE ENZYME | DNA-POLYMERASES | DAMAGE | Guanine Nucleotides - metabolism | DNA, Bacterial - metabolism | Guanine - analogs & derivatives | Escherichia coli - drug effects | Pyrophosphatases - genetics | DNA Polymerase II - metabolism | DNA Breaks, Double-Stranded | DNA-Directed DNA Polymerase - genetics | Guanine - metabolism | Norfloxacin - pharmacology | Escherichia coli - metabolism | Ampicillin - pharmacology | Deoxyguanine Nucleotides - metabolism | DNA Polymerase beta - metabolism | DNA Polymerase I - genetics | DNA Polymerase II - genetics | DNA Polymerase beta - genetics | RNA, Bacterial - metabolism | DNA Glycosylases - metabolism | Oxidation-Reduction | DNA Glycosylases - genetics | Escherichia coli Proteins - metabolism | Hydroxyl Radical - metabolism | Microbial Viability | Kanamycin - pharmacology | Pyrophosphatases - metabolism | Escherichia coli - genetics | Models, Biological | Escherichia coli Proteins - genetics | Anti-Bacterial Agents - pharmacology | DNA-Directed DNA Polymerase - metabolism | DNA Polymerase I - metabolism | Physiological aspects | Oxidation-reduction reaction | Research | Health aspects | Guanine | Drug therapy
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2019, Volume 14, Issue 3, p. e0213383
Replicative DNA polymerases are frequently stalled at damaged template strands. Stalled replication forks are restored by the DNA damage tolerance (DDT... 
POLYMERASE-DELTA | CELLS | RECOMBINATION | REPAIR | ETA | MECHANISM | UV PHOTOPRODUCTS | MULTIDISCIPLINARY SCIENCES | BREAKS | GENE CONVERSION | FRAGILE SITE STABILITY | Multifunctional Enzymes - genetics | DNA Primase - deficiency | Humans | Multifunctional Enzymes - deficiency | DNA Primase - metabolism | Templates, Genetic | Multifunctional Enzymes - metabolism | DNA-Directed DNA Polymerase - deficiency | DNA-Directed DNA Polymerase - genetics | DNA Polymerase beta - deficiency | Nuclear Proteins - deficiency | DNA Primase - genetics | DNA - biosynthesis | DNA Polymerase beta - metabolism | Nuclear Proteins - genetics | DNA Polymerase beta - genetics | Cell Line | Avian Proteins - metabolism | DNA Replication | Nuclear Proteins - metabolism | Gene Knockout Techniques | DNA - genetics | Genes, Immunoglobulin | Animals | Avian Proteins - deficiency | Chickens | DNA Repair | DNA Damage | DNA-Directed DNA Polymerase - metabolism | Avian Proteins - genetics | Usage | Nucleotide sequence | DNA polymerases | Genetic aspects | Research | Brewer's yeast | DNA repair | DNA damage | DNA | Neomycin | Genetic research | DNA synthesis | Cells | Cell culture | Health sciences | Hydrogen peroxide | DNA polymerase | Poultry | Homologous recombination | Homology | Genomes | Compounds | Replication forks | Mammalian cells | Damage tolerance | Proteins | Pathways | Cell cycle | Life sciences | Chemical synthesis | Chromosomes | Deoxyribonucleic acid--DNA | Medical research | Phenotypes | Immunoglobulins | U.V. radiation | Immunological tolerance | Crossovers | Switching | Chemical damage | Mutants | Medicine | Polymerase | DNA biosynthesis | Organic chemistry | Sensitivity | Lymphocytes B | Pharmacy | Cell lines | Sensitivity enhancement | In vivo methods and tests | Gene conversion | DNA-directed DNA polymerase | Cancer | Life Sciences | Biochemistry, Molecular Biology | Genomics | Deoxyribonucleic acid
Journal Article
Nucleic acids research, ISSN 1362-4962, 2019, Volume 47, Issue 13, pp. 6932 - 6945
Journal Article
Nature (London), ISSN 1476-4687, 2014, Volume 507, Issue 7490, pp. 124 - 128
Journal Article
PLoS genetics, ISSN 1553-7404, 2015, Volume 11, Issue 8, p. e1005482
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2012, Volume 336, Issue 6079, pp. 341 - 344
Journal Article
Journal Article
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 10/2017, Volume 216, Issue 10, pp. 3097 - 3115
.... RAD18 and its effector, DNA polymerase. (Pol kappa), sustained ongoing DNA synthesis in cells harboring elevated CDK2 activity... 
STRUCTURED DNA | STALLED REPLICATION | CANCER DEVELOPMENT | PCNA MONOUBIQUITINATION | PIGMENTOSUM VARIANT CELLS | GENOME INTEGRITY | TRANSLESION SYNTHESIS | INDUCED SENESCENCE | S-PHASE CHECKPOINT | DAMAGE BYPASS | CELL BIOLOGY | Neoplasms - metabolism | Protein-Tyrosine Kinases - metabolism | Humans | M Phase Cell Cycle Checkpoints - genetics | Drug Resistance, Neoplasm | DNA-Directed DNA Polymerase - genetics | Tumor Suppressor Protein p53 - genetics | Cell Cycle Proteins - antagonists & inhibitors | DNA Breaks, Single-Stranded | DNA-Binding Proteins - metabolism | Protein-Tyrosine Kinases - genetics | DNA, Neoplasm - biosynthesis | G2 Phase Cell Cycle Checkpoints - drug effects | Neoplasms - genetics | Cell Cycle Proteins - genetics | Nuclear Proteins - genetics | Pyrazoles - pharmacology | A549 Cells | Cyclin-Dependent Kinase 2 - metabolism | M Phase Cell Cycle Checkpoints - drug effects | Signal Transduction | Cell Cycle Proteins - metabolism | Tumor Suppressor Protein p53 - metabolism | Ubiquitin-Protein Ligases - metabolism | Cyclin-Dependent Kinase 2 - genetics | Nuclear Proteins - metabolism | Pyrimidines - pharmacology | DNA-Binding Proteins - genetics | Neoplasms - drug therapy | G2 Phase Cell Cycle Checkpoints - genetics | Animals | Nuclear Proteins - antagonists & inhibitors | Mice | DNA, Neoplasm - genetics | DNA-Directed DNA Polymerase - metabolism | Ubiquitin-Protein Ligases - genetics | Protein-Tyrosine Kinases - antagonists & inhibitors
Journal Article