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Science, ISSN 0036-8075, 4/2012, Volume 336, Issue 6079, pp. 315 - 319
A detailed understanding of the mechanisms that underlie antibiotic killing is important for the derivation of new classes of antibiotics and clinically useful... 
RESEARCH ARTICLE | Antibiotics | Cell death | DNA | Fluorescence | Cytotoxicity | Oxidation | Nucleotides | Overproduction | Genetic mutation | Guanine nucleotides | MUTAGENESIS | PROTEIN | REPLICATION | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | DOUBLE-STRAND BREAKS | HYDROGEN-PEROXIDE | MECHANISMS | MUTT-TYPE ENZYME | DNA-POLYMERASES | DAMAGE | Guanine Nucleotides - metabolism | DNA, Bacterial - metabolism | Guanine - analogs & derivatives | Escherichia coli - drug effects | Pyrophosphatases - genetics | DNA Polymerase II - metabolism | DNA Breaks, Double-Stranded | DNA-Directed DNA Polymerase - genetics | Guanine - metabolism | Norfloxacin - pharmacology | Escherichia coli - metabolism | Ampicillin - pharmacology | Deoxyguanine Nucleotides - metabolism | DNA Polymerase beta - metabolism | DNA Polymerase I - genetics | DNA Polymerase II - genetics | DNA Polymerase beta - genetics | RNA, Bacterial - metabolism | DNA Glycosylases - metabolism | Oxidation-Reduction | DNA Glycosylases - genetics | Escherichia coli Proteins - metabolism | Hydroxyl Radical - metabolism | Microbial Viability | Kanamycin - pharmacology | Pyrophosphatases - metabolism | Escherichia coli - genetics | Models, Biological | Escherichia coli Proteins - genetics | Anti-Bacterial Agents - pharmacology | DNA-Directed DNA Polymerase - metabolism | DNA Polymerase I - metabolism | Physiological aspects | Oxidation-reduction reaction | Research | Health aspects | Guanine | Drug therapy | Index Medicus | Adjuvants
Journal Article
Science, ISSN 0036-8075, 4/2012, Volume 336, Issue 6079, pp. 341 - 344
Journal Article
Journal Article
PLoS Genetics, ISSN 1553-7390, 10/2014, Volume 10, Issue 10, pp. e1004654 - e1004654
Although a defect in the DNA polymerase POLQ leads to ionizing radiation sensitivity in mammalian cells, the relevant enzymatic pathway has not been... 
GENOMIC INSTABILITY | BASE-EXCISION-REPAIR | STRAND BREAK REPAIR | END-JOINING PATHWAY | SOMATIC HYPERMUTATION | CROSS-LINK REPAIR | HUMAN-CELLS | GENETICS & HEREDITY | SEQUENCING REVEALS | THETA POLQ | TRANSLOCATION FORMATION | DNA End-Joining Repair - genetics | Humans | Mice, Inbred C57BL | Cells, Cultured | B-Lymphocytes - physiology | Bone Marrow Cells - physiology | Bone Marrow Cells - radiation effects | DNA Breaks, Double-Stranded | DNA-Directed DNA Polymerase - genetics | Animals | Metabolic Networks and Pathways | Mice, Mutant Strains | HEK293 Cells | Bleomycin - pharmacology | Bone Marrow Cells - drug effects | Female | DNA-Directed DNA Polymerase - metabolism | Chromosomal Instability | Immunoglobulin Class Switching | DNA polymerases | Genetic research | Research | Chromosomes | Suppression, Genetic | Index Medicus | Basic Medicine | Other Basic Medicine | Medical Genetics | Medicinsk genetik | Medical Biotechnology | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Medicinsk bioteknologi | Annan medicinsk grundvetenskap | Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy) | Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci) | Proteins | Enzymes | DNA polymerase | Deoxyribonucleic acid | DNA | Genomes | Grants | DNA repair | Experiments | Cancer
Journal Article
PLoS Genetics, ISSN 1553-7390, 08/2015, Volume 11, Issue 8, pp. e1005482 - e1005482
Journal Article
Nature, ISSN 0028-0836, 08/2018, Volume 560, Issue 7717, pp. 248 - 252
Journal Article
Nature Genetics, ISSN 1061-4036, 02/2015, Volume 47, Issue 3, pp. 257 - 262
Journal Article
Journal Article