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DNA repair, ISSN 1568-7864, 2002
Journal
Cell (Cambridge), ISSN 0092-8674, 2011, Volume 145, Issue 1, pp. 54 - 66
Journal Article
Nature (London), ISSN 1476-4687, 2014, Volume 508, Issue 7495, pp. 222 - 227
Activated RAS GTPase signalling is a critical driver of oncogenic transformation and malignant disease. Cellular models of RAS-dependent cancers have been used... 
CELL LUNG-CANCER | RAS-TRANSFORMATION | OVEREXPRESSION | OXIDATIVE STRESS | HMTH1 | MESSENGER-RNA | GENE | MULTIDISCIPLINARY SCIENCES | HUMAN MUTT HOMOLOG | TUMORIGENESIS | SMALL-MOLECULE INHIBITION | ras Proteins - genetics | Colonic Neoplasms - genetics | Proto-Oncogene Proteins p21(ras) | Pyridines - chemistry | Colonic Neoplasms - drug therapy | Humans | Substrate Specificity | DNA Breaks, Single-Stranded - drug effects | Protein Kinase Inhibitors - chemistry | Pyrazoles - chemistry | Phosphoric Monoester Hydrolases - biosynthesis | DNA Repair Enzymes - metabolism | Female | Antineoplastic Agents - pharmacology | DNA Repair Enzymes - antagonists & inhibitors | Homeostasis - drug effects | Aminoquinolines - pharmacology | DNA Repair Enzymes - chemistry | Disease Models, Animal | Phosphoric Monoester Hydrolases - antagonists & inhibitors | Pyrazoles - pharmacology | Crystallization | Models, Molecular | Proto-Oncogene Proteins - genetics | Antineoplastic Agents - chemistry | Mice, SCID | Nucleotides - metabolism | Xenograft Model Antitumor Assays | Animals | Colonic Neoplasms - pathology | DNA Repair | DNA Repair Enzymes - biosynthesis | Proteomics | Protein Conformation | Mice | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Phosphoric Monoester Hydrolases - metabolism | Phosphoric Monoester Hydrolases - chemistry | Crizotinib | Enzymes | Colon cancer | Physiological aspects | Genetic aspects | Research | Nucleotides | Studies | Oxidative stress | Inhibitor drugs | Medical prognosis | Homeostasis | Mutation | Kinases | Experiments | Cancer | Life Sciences | crizotinib | cancer | stereoselectivity | MTH1 | DNA repair | drug
Journal Article
2014, ISBN 9780815344858, xvi, 399
"Genome Stability: DNA Repair and Recombination describes the various mechanisms of repairing DNA damage by recombination, most notably the repair of... 
Models, Molecular | Genomic Instability | Recombinational DNA Repair | Genetic recombination | DNA Repair
Book
Nature (London), ISSN 1476-4687, 2016, Volume 535, Issue 7612, pp. 382 - 387
Cells deficient in the Brca1 and Brca2 genes have reduced capacity to repair DNA double-strand breaks by homologous recombination and consequently are... 
RECOMBINATION | RIF1 | RESECTION | MUTANT-CELLS | 53BP1 | MULTIDISCIPLINARY SCIENCES | DNA-DAMAGE | RESISTANCE | HOMOLOGY-DIRECTED REPAIR | CONDITIONAL MOUSE MODEL | PTIP | Embryonic Stem Cells - metabolism | DNA Replication - drug effects | Homologous Recombination | DNA Repair - genetics | DNA Breaks, Double-Stranded | DNA-Binding Proteins - metabolism | MRE11 Homologue Protein | Neoplasms - genetics | Gene Deletion | Nuclear Proteins - deficiency | DNA Repair Enzymes - metabolism | DNA Damage - genetics | Genes, BRCA2 | DNA - biosynthesis | Female | DNA Repair Enzymes - antagonists & inhibitors | Genes, BRCA1 | Nuclear Proteins - genetics | DNA Helicases - genetics | DNA Damage - drug effects | DNA Repair - drug effects | DNA-Binding Proteins - antagonists & inhibitors | Cisplatin - pharmacology | DNA - metabolism | Carrier Proteins - genetics | Poly(ADP-ribose) Polymerase Inhibitors - pharmacology | Drug Resistance, Neoplasm - genetics | Animals | Poly(ADP-ribose) Polymerases - genetics | DNA Replication - physiology | Embryonic Stem Cells - drug effects | Cell Line, Tumor | Mice | Poly (ADP-Ribose) Polymerase-1 | Neoplasms - pathology | Drug Resistance, Neoplasm - drug effects | Physiological aspects | Chemotherapy | Replication fork | B cells | DNA damage | Cancer | Proteins | Lymphocytes | Stem cells | Breast cancer | Drug resistance | Deoxyribonucleic acid--DNA | Tumors
Journal Article
PLoS genetics, ISSN 1553-7404, 2008, Volume 4, Issue 6, pp. e1000110 - e1000110
Journal Article
Journal Article
Nature genetics, ISSN 1546-1718, 2010, Volume 42, Issue 3, pp. 245 - 249
Journal Article
Oncogene, ISSN 1476-5594, 2012, Volume 32, Issue 30, pp. 3552 - 3558
Journal Article
Journal Article