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Neuron (Cambridge, Mass.), ISSN 0896-6273, 02/2013, Volume 77, Issue 3, pp. 472 - 484
Major outputs of the neocortex are conveyed by corticothalamic axons (CTAs), which form reciprocal connections with thalamocortical axons, and... 
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Thyroid Nuclear Factor 1 | Age Factors | Embryo, Mammalian | Leukocyte L1 Antigen Complex - metabolism | Gene Expression Regulation, Developmental - genetics | Axons - physiology | Cerebral Cortex - cytology | Neural Pathways - physiology | DNA-Binding Proteins - metabolism | POU Domain Factors - genetics | tau Proteins - genetics | Thalamus - physiology | Contactin 2 - metabolism | Repressor Proteins - metabolism | Glycoproteins - genetics | Tumor Suppressor Proteins - metabolism | Wnt3A Protein - genetics | Membrane Proteins - genetics | Mice, Inbred C57BL | Mice, Transgenic | Nuclear Proteins - metabolism | Transcription Factors - genetics | Nerve Tissue Proteins - genetics | Homeodomain Proteins - genetics | Membrane Glycoproteins - genetics | Nerve Tissue Proteins - metabolism | S100 Calcium Binding Protein G - metabolism | Transcription Factors - metabolism | Animals | Calbindin 2 | Thalamus - cytology | Cerebral Cortex - physiology | Luminescent Proteins - genetics | Mice | Body Patterning - genetics | Luminescent Proteins - metabolism | Developmental biology | Neurons | Studies | Laboratories | Experiments | Index Medicus | Repressor Proteins | Cerebral Cortex | Cellular Biology | Neural Pathways | tau Proteins | Life Sciences | Contactin 2 | Gene Expression Regulation, Developmental | Body Patterning | Thalamus | Membrane Glycoproteins | Luminescent Proteins | DNA-Binding Proteins | POU Domain Factors | Calcium-Binding Protein, Vitamin D-Dependent | Glycoproteins | Nerve Tissue Proteins | Nuclear Proteins | Membrane Proteins | Axons | Homeodomain Proteins | Leukocyte L1 Antigen Complex | Transcription Factors | Wnt3A Protein | Tumor Suppressor Proteins | reciprocal connections | handshake | waiting period | PlexinD1 | axon guidance | Sema3E | thalamocortical | corticothalamic
Journal Article
Nature immunology, ISSN 1529-2908, 12/2013, Volume 14, Issue 12, pp. 1247 - 1255
The inflammasome adaptor ASC contributes to innate immunity through the activation of caspase-1. Here we found that signaling pathways dependent on the kinases... 
Life Sciences & Biomedicine | Immunology | Science & Technology | Interleukin-18 - immunology | Inflammasomes - metabolism | Cytoskeletal Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Protein-Tyrosine Kinases - metabolism | Dendritic Cells - immunology | Humans | JNK Mitogen-Activated Protein Kinases - immunology | Caspase 1 - metabolism | Immunoblotting | Intracellular Signaling Peptides and Proteins - metabolism | RNA Interference | Bone Marrow Cells - immunology | Phosphorylation - immunology | JNK Mitogen-Activated Protein Kinases - genetics | Intracellular Signaling Peptides and Proteins - genetics | Syk Kinase | Carrier Proteins - immunology | DNA-Binding Proteins | Tyrosine - immunology | Mice, Knockout | Macrophages - metabolism | Tyrosine - metabolism | Lipopolysaccharides - pharmacology | Mice | Interleukin-18 - metabolism | Intracellular Signaling Peptides and Proteins - immunology | JNK Mitogen-Activated Protein Kinases - metabolism | Caspase 1 - immunology | Protein-Tyrosine Kinases - immunology | Protein-Tyrosine Kinases - genetics | HEK293 Cells | Cytoskeletal Proteins - metabolism | Female | Nuclear Proteins - genetics | Dendritic Cells - metabolism | Macrophages - immunology | Mice, Inbred C57BL | Cells, Cultured | Nuclear Proteins - metabolism | Nuclear Proteins - immunology | Inflammasomes - genetics | Carrier Proteins - genetics | Animals | Apoptosis Regulatory Proteins | Carrier Proteins - metabolism | Cytoskeletal Proteins - immunology | CARD Signaling Adaptor Proteins | Inflammasomes - immunology | Macrophages - drug effects | Nigericin - pharmacology | Bone Marrow Cells - metabolism | Tyrosine - genetics | Cellular signal transduction | Inflammation | Genetic aspects | Research | Properties | Phosphotransferases | Index Medicus
Journal Article
Molecular cell, ISSN 1097-2765, 10/2009, Volume 36, Issue 1, pp. 39 - 50
In the largest E3 ligase subfamily, Cul3 binds a BTB domain, and an associated protein-interaction domain such as MATH recruits substrates for ubiquitination... 
PROTEINS | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Transcription Factors - chemistry | Humans | Crystallography, X-Ray | Drosophila Proteins - metabolism | Mutation - physiology | Protein Multimerization - physiology | Protein Structure, Quaternary - physiology | Ubiquitination - physiology | Peptide Fragments - genetics | Repressor Proteins - metabolism | Amino Acid Sequence | Ubiquitin-Protein Ligases - metabolism | Models, Molecular | Repressor Proteins - genetics | Recombinant Fusion Proteins - chemistry | Nuclear Proteins - chemistry | Ubiquitin-Protein Ligases - chemistry | DNA-Binding Proteins - chemistry | Cullin Proteins - chemistry | Peptide Fragments - chemistry | Phosphoprotein Phosphatases - genetics | Consensus Sequence - physiology | Recombinant Fusion Proteins - genetics | Histones - metabolism | Ubiquitin-Protein Ligases - genetics | Drosophila melanogaster | Phosphoprotein Phosphatases - chemistry | Protein Binding - physiology | Adaptor Proteins, Signal Transducing - chemistry | Histones - chemistry | Protein Interaction Domains and Motifs - physiology | Phosphoprotein Phosphatases - metabolism | Recombinant Fusion Proteins - metabolism | DNA-Binding Proteins - metabolism | Cullin Proteins - metabolism | Nuclear Proteins - genetics | Peptide Fragments - metabolism | Repressor Proteins - chemistry | Nuclear Proteins - metabolism | Drosophila Proteins - chemistry | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Cullin Proteins - genetics | Transcription Factors - metabolism | Animals | Histones - genetics | Adaptor Proteins, Signal Transducing - genetics | Drosophila Proteins - genetics | Adaptor Proteins, Signal Transducing - metabolism | Ubiquitin | Chromatin | Phosphatases | Ligases | Index Medicus | CHROMATIN | BASIC BIOLOGICAL SCIENCES | SUBSTRATES | FLEXIBILITY | GENERAL AND MISCELLANEOUS//MATHEMATICS, COMPUTING, AND INFORMATION SCIENCE | LIGASES | DIMERIZATION | DIMERS | PHOSPHATASES
Journal Article
Nature (London), ISSN 1476-4687, 09/2004, Volume 431, Issue 7010, pp. 873 - 878
.... The complex, termed hPRC1L (human Polycomb repressive complex 1-like), is composed of several Polycomb-group proteins including Ring1, Ring2, Bmi1 and HPH2... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Nuclear Proteins - isolation & purification | Nucleosomes - chemistry | Humans | Multiprotein Complexes | Ubiquitin - metabolism | Molecular Sequence Data | Drosophila melanogaster - genetics | Promoter Regions, Genetic - genetics | Protein Subunits - metabolism | DNA-Binding Proteins - metabolism | Protein Subunits - isolation & purification | Repressor Proteins - isolation & purification | Response Elements - genetics | Nuclear Proteins - genetics | Proto-Oncogene Proteins - isolation & purification | Repressor Proteins - metabolism | Protein Subunits - genetics | Proto-Oncogene Proteins - metabolism | Amino Acid Sequence | Cell Line | Catalytic Domain | Repressor Proteins - chemistry | Gene Silencing | Ubiquitin-Protein Ligases - metabolism | Nucleosomes - metabolism | Repressor Proteins - genetics | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Polycomb-Group Proteins | Transcription Factors - genetics | DNA-Binding Proteins - genetics | DNA-Binding Proteins - isolation & purification | Ubiquitin-Protein Ligases - chemistry | DNA-Binding Proteins - chemistry | Homeodomain Proteins - genetics | Transcription Factors - metabolism | Polycomb Repressive Complex 2 | Animals | Polycomb Repressive Complex 1 | Transcription Factors - isolation & purification | Ubiquitin-Protein Ligases - isolation & purification | Protein Subunits - chemistry | Drosophila Proteins - genetics | HeLa Cells | Histones - metabolism | Ubiquitin-Protein Ligases - genetics | Proteins | Enzymes | Cell culture | Chromatin | Biochemistry | Index Medicus
Journal Article
2009, Advances in experimental medicine and biology, ISBN 9781441902955, Volume 650., xvii, 199
Features findings concerning the biochemical properties of the V(D)J recombinase (Swanson), it's buried and potentially harmful transposase and translocase... 
VDJ Recombinases | Recombinant Proteins | Genetic recombination | Recombination, Genetic | DNA-binding proteins
Book
Nature biotechnology, ISSN 1546-1696, 06/2002, Volume 20, Issue 6, pp. 619 - 622
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 09/2009, Volume 106, Issue 37, pp. 15628 - 15632
...Assembly of the Cdc45-Mcm2–7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins Jun-Sub Im a,1 , Sang-Hee Ki a,1 , Andrea Farina b... 
Cdc7-Dbf4 kinase | Cyclin-dependent kinase | Cdc45-Mcm-GINS complex | Bimolecular fluorescence complementation | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Minichromosome Maintenance Proteins | Cyclin-Dependent Kinases - metabolism | RecQ Helicases - metabolism | Humans | Multiprotein Complexes | Bacterial Proteins - chemistry | RecQ Helicases - genetics | Minichromosome Maintenance Complex Component 7 | Minichromosome Maintenance Complex Component 2 | Recombinant Fusion Proteins - metabolism | Cell Cycle Proteins - chemistry | DNA-Binding Proteins - metabolism | Cell Cycle Proteins - genetics | Luminescent Proteins - chemistry | Nuclear Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Chromosomal Proteins, Non-Histone - metabolism | Bacterial Proteins - genetics | Cell Cycle Proteins - metabolism | Nuclear Proteins - metabolism | Recombinant Fusion Proteins - chemistry | DNA-Binding Proteins - genetics | Nuclear Proteins - chemistry | DNA-Binding Proteins - chemistry | Chromosomal Proteins, Non-Histone - genetics | Carrier Proteins - metabolism | Cell Cycle | Recombinant Fusion Proteins - genetics | Bacterial Proteins - metabolism | Luminescent Proteins - genetics | RecQ Helicases - chemistry | HeLa Cells | Chromosomal Proteins, Non-Histone - chemistry | Luminescent Proteins - metabolism | Proteins | DNA replication | HeLa cells | Physiological aspects | Genetic aspects | Research | Molecular biology | Index Medicus | Biological Sciences | bimolecular fluorescence complementation | cyclin-dependent kinase
Journal Article
Oncogene, ISSN 1476-5594, 02/2007, Volume 26, Issue 32, pp. 4635 - 4647
...). APBs are PML bodies containing telomeric DNA and telomere-binding proteins, and are observed only in a small fraction of cells within asynchronously dividing ALT-positive cell populations... 
Telomeres | siRNA | Alternative lengthening of telomeres | Methionine restriction | PML | ALT-associated PML bodies | Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Humans | Neoplasm Proteins - antagonists & inhibitors | Resting Phase, Cell Cycle | Autoantigens - genetics | RNA Interference | Neoplasm Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Telomeric Repeat Binding Protein 2 - antagonists & inhibitors | DNA Repair Enzymes - physiology | DNA-Binding Proteins - physiology | DNA-Binding Proteins - antagonists & inhibitors | Telomeric Repeat Binding Protein 2 - physiology | Genetic Techniques | Autoantigens - physiology | Tumor Suppressor Proteins - physiology | G1 Phase | Cell Line, Tumor | Intracellular Signaling Peptides and Proteins - physiology | Cell Cycle Proteins - physiology | Telomeric Repeat Binding Protein 1 - physiology | Tumor Suppressor Proteins - antagonists & inhibitors | Neoplasm Proteins - physiology | DNA Repair Enzymes - genetics | Telomeric Repeat Binding Protein 1 - genetics | Cell Cycle Proteins - antagonists & inhibitors | MRE11 Homologue Protein | Telomere-Binding Proteins - genetics | Tumor Suppressor Proteins - genetics | Telomere-Binding Proteins - physiology | Cell Cycle Proteins - genetics | Telomere - metabolism | DNA Repair Enzymes - antagonists & inhibitors | Nuclear Proteins - genetics | Methionine - deficiency | Telomere - genetics | Transcription Factors - physiology | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | RNA, Small Interfering - pharmacology | Antigens, Nuclear - physiology | Transcription Factors - antagonists & inhibitors | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Telomere-Binding Proteins - antagonists & inhibitors | Antigens, Nuclear - genetics | Nuclear Proteins - antagonists & inhibitors | Telomeric Repeat Binding Protein 1 - antagonists & inhibitors | Cell Proliferation - drug effects | Nuclear Proteins - physiology | Telomeric Repeat Binding Protein 2 - genetics | Tumor Suppressor p53-Binding Protein 1 | Promyelocytic Leukemia Protein | Physiological aspects | Genetic aspects | Research | Cancer cells | Proteins | Ribonucleic acid | Cell cycle | Genetics | Ribonucleic acid--RNA | DNA repair | Cancer | Index Medicus
Journal Article