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1. Full Text Discovery of epigenetically silenced genes by methylated DNA lmmunoprecipitation in colon cancer cells
by Jacinto, FV and Ballestar, E and Ropero, S and Esteller, M
CANCER RESEARCH, ISSN 0008-5472, 12/2007, Volume 67, Issue 24, pp. 11481 - 11486
CpG island promoter hypermethylation of tumor suppressor genes is a common hallmark of human cancer, and new large-scale epigenomic technologies might be... 
DNMT1 | ONCOLOGY
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2. Full Text Decreased generation of c-terminal fragments of apoer2 and increased reelin expression in Alzheimer’s disease
by Mata-Balaguer, Trinidad and Cuchillo-Ibañez, Inmaculada and Calero, Miguel and Ferrer, Isidro and Sáez-Valero, Javier
FASEB Journal, ISSN 0892-6638, 07/2018, Volume 32, Issue 7, pp. 3536 - 3546
Brain | DNMT1 | ApoE | Methylation
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3. Full Text ADP-ribose polymers localized on Ctcf-Parp1-Dnmt1 complex prevent methylation of Ctcf target sites
by Zampieri, Michele and Guastafierro, Tiziana and Calabrese, Roberta and Ciccarone, Fabio and Bacalini, Maria G and Reale, Anna and Perilli, Mariagrazia and Passananti, Claudio and Caiafa, Paola
Biochemical Journal, ISSN 0264-6021, 01/2012, Volume 441, Issue 2, pp. 645 - 652
PARylation [poly(ADP-ribosyl)ation] is involved in the maintenance of genomic methylation patterns through its control of Dram 1 [DNA... 
DNA methylation | Epigenetics | Poly(ADP-ribosyl)ation (PARylation) | DNA methyltranferase 1 (Dnmt1) | CCCTC-binding factor (Ctcf) | Poly(ADP-ribose) polymerase 1 (Parp1) | POLY(ADP-RIBOSYL)ATION REACTIONS | BIOCHEMISTRY & MOLECULAR BIOLOGY | poly(ADP-ribosyl)ation (PARylation) | epigenetics | HUMAN GENOME | GENE | EMBRYONIC STEM-CELLS | INSULATOR PROTEIN CTCF | UNMETHYLATED STATE | TUMOR-SUPPRESSOR | poly(ADP-ribose) polymerase 1 (Parp1) | CPG ISLANDS | BINDING | DNA (Cytosine-5-)-Methyltransferases - metabolism | Multiprotein Complexes - metabolism | DNA Methylation | Poly Adenosine Diphosphate Ribose - metabolism | Poly(ADP-ribose) Polymerases - metabolism | DNA (Cytosine-5-)-Methyltransferase 1 | CCCTC-Binding Factor | Epigenesis, Genetic | CpG Islands - physiology | Repressor Proteins - metabolism | poly(ADP-ribose) polymerase 1 | DNMT1 protein | genomics | Promoters | ADP-ribosylation | CpG islands | Life Sciences | Poly(ADP-ribose) Polymerases | DNA (Cytosine-5-)-Methyltransferase | Multiprotein Complexes | Repressor Proteins | Biochemistry, Molecular Biology | CpG Islands | Poly Adenosine Diphosphate Ribose | Molecular biology | DMR1, differentially methylated region 1 | Ab, antibody | poly(ADPribosyl)ation (PARylation) | H2B, histone 2B | PARG, poly(ADP-ribose) glycohydrolase | Ctcf, CCCTC-binding factor | IP, immunoprecipitation | DTT, dithiothreitol | ChIP, chromatin immunoprecipitation | TBST, Tris-buffered saline plus 0.05% Tween 20 | Dnmt1, DNA (cytosine-5)-methyltransferase 1 | Parp1, poly(ADP-ribose) polymerase 1 | H1, histone 1 | CGI, CpG island | dsDNA, double-stranded DNA | PARylation, poly(ADP-ribosyl)ation | PARs, poly(ADP-ribose) polymers | RE-ChIP, sequential ChIP
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4. Full Text Enhanced anticancer effects of a methylation inhibitor by inhibiting a novel DNMT1 target, CEP 131, in cervical cancer
by Dong Hyun Kim and and Hye-min Kim and Pham Thi Thu Huong and Ho-jin Han and Joonsung Hwang and Hyunjoo Cha-molstad and Kyung Ho Lee and In-ja Ryoo and Kyoon Eon Kim and Yang Hoon Huh and Jong Seog Ahn and Yong Tae Kwon and Nak-kyun Soung and Bo Yeon Kim
BMB Reports, ISSN 1976-6696, 2019, Volume 52, Issue 5, pp. 342 - 347
Methylation is a primary epigenetic mechanism regulating gene expression. 5-aza-2'-deoxycytidine is an FDA-approved drug prescribed for treatment of cancer by... 
DNMT1 | Anti-cancer | Centrosome | CEP131
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5. Full Text Narcolepsy is a common phenotype in HSAN IE and ADCA-DN
by Moghadam, Keivan Kaveh and Pizza, Fabio and La Morgia, Chiara and Franceschini, Christian and Tonon, Caterina and Lodi, Raffaele and Barboni, Piero and Seri, Marco and Ferrari, Simona and Liguori, Rocco and Donadio, Vincenzo and Parchi, Piero and Cornelio, Ferdinando and Inzitari, Domenico and Mignarri, Andrea and Capocchi, Giuseppe and Dotti, Maria Teresa and Winkelmann, Juliane and Lin, Ling and Mignot, Emmanuel and Carelli, Valerio and Plazzi, Giuseppe
Brain, ISSN 0006-8950, 2014, Volume 137, Issue 6, pp. 1643 - 1655
Mutations in DNA methyltransferase type I are associated with two distinct autosomal dominant diseases: HSAN IE and ADCA-DN. By studying five patients from... 
neurodegeneration | cataplexy | DNMT1 | ADCA-DN | narcolepsy | HSAN IE | CEREBROSPINAL-FLUID | NEUROSCIENCES | HEREDITARY SENSORY NEUROPATHY | CLINICAL NEUROLOGY | SYMPTOMATIC NARCOLEPSY | HEARING-LOSS | MUTATION | METHYLTRANSFERASE 1 | DEAFNESS | CREUTZFELDT-JAKOB-DISEASE | DOMINANT CEREBELLAR-ATAXIA | Genetic Predisposition to Disease - genetics | Deafness - genetics | Humans | Middle Aged | Male | Mutation - genetics | Narcolepsy - diagnosis | Narcolepsy - genetics | Phenotype | Olivopontocerebellar Atrophies - diagnosis | Olivopontocerebellar Atrophies - genetics | Pedigree | Adult | Female | Hereditary Sensory and Autonomic Neuropathies - genetics | Hereditary Sensory and Autonomic Neuropathies - diagnosis | 14-3-3 Proteins - genetics | Index Medicus | Abridged Index Medicus
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6. Full Text The enhancement of combination of berberine and metformin in inhibition of DNMT1 gene expression through interplay of SP1 and PDPK1
by Zheng, Fang and Wu, JingJing and Tang, Qing and Xiao, Qian and Wu, WanYin and Hann, Swei Sunny
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 01/2018, Volume 22, Issue 1, pp. 600 - 612
Berberine (BBR), one of active alkaloid found in the rhizome, exhibited anti‐cancer properties. We have showed that BBR inhibited growth of non‐small cell lung... 
Berberine | DNMT1 | Metformin | NSCLC | PDPK1 | SP1 | MEDICINE, RESEARCH & EXPERIMENTAL | INDUCED-APOPTOSIS | REGULATING DNMT1 | EP4 EXPRESSION | CHINESE HERBAL MEDICINE | LUNG-CANCER CELLS | CELL BIOLOGY | DNA METHYLTRANSFERASE 1 | HEPATOCELLULAR-CARCINOMA | GASTRIC-CANCER | QUALITY-OF-LIFE | NF-KAPPA-B | Cell Proliferation - genetics | Neoplasm Invasiveness | Humans | Metformin - pharmacology | Sp1 Transcription Factor - metabolism | 3-Phosphoinositide-Dependent Protein Kinases - metabolism | Cell Movement - genetics | DNA (Cytosine-5-)-Methyltransferase 1 - metabolism | Drug Synergism | Berberine - pharmacology | Cell Movement - drug effects | DNA (Cytosine-5-)-Methyltransferase 1 - genetics | Cell Cycle Checkpoints - drug effects | Cell Line, Tumor | Cell Cycle Checkpoints - genetics | Cell Proliferation - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Genetic research | Hypoglycemic agents | Methyltransferases | Lung cancer, Non-small cell | Gene expression | Genes | Cell proliferation | Lung cancer | DNMT1 protein | Non-small cell lung carcinoma | MAP kinase | Kinases | Sp1 protein | Anticancer properties | Proteins | Protein kinase | Cell cycle | Dnmt1 gene | Forkhead protein | DNA methyltransferase | Inhibition | Cell migration | Deoxyribonucleic acid--DNA | FOXO3 protein | Cancer | Original
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7. Full Text Crucifera sulforaphane (SFN) inhibits the growth of nasopharyngeal carcinoma through DNA methyltransferase 1 (DNMT1)/Wnt inhibitory factor 1 (WIF1) axis
by Chen, Luo and Chan, Lai Sheung and Lung, Hong Lok and Lung, Maria Li and Yip, Timothy Tak Chun and Ngan, Roger Kai Cheong and Wong, Jonathan Woon Chung and Lo, Kwok Wai and Ng, Wai Tong and Lee, Anne Wing Mui and Tsao, George Sai Wah and Mak, Nai Ki
Phytomedicine, ISSN 0944-7113, 10/2019, Volume 63, p. 153058
Sulforaphane (SFN), a natural compound present in cruciferous vegetable, has been shown to possess anti-cancer activities. Cancer stem cell (CSC) in bulk tumor... 
Nasopharyngeal carcinoma | DNMT1 | WIF1 | Sulforaphane
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8. Full Text 15-Deoxy-Δ 12,14 -prostaglandin J 2 up-regulates the expression of 15-hydroxyprostaglandin dehydrogenase through DNA methyltransferase 1 inactivation
by Jang, Hye-Ok and Lee, Ha-Na and Woo, Jeong-Hwa and Lee, Ja-Young and Kim, Areumnuri and Lee, Jin Kyung and Kim, Do-Hee and Surh, Young-Joon and Na, Hye-Kyung
Free Radical Research, ISSN 1071-5762, 03/2019, Volume 53, Issue 3, pp. 335 - 347
DNMT1 | 15-PGDH | methylation | breast cancer | 15d-PGJ
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9. Full Text MyD88 hypermethylation mediated by DNMT1 is associated with LTA-induced inflammatory response in human odontoblast-like cells
by Meng, Runsha and Li, Di and Feng, Zhihui and Xu, Qiong
Cell and Tissue Research, ISSN 0302-766X, 2019, Volume 376, Issue 3, pp. 413 - 423
Dental caries is a chronic, infectious, and destructive disease that allows bacteria to break into the dental pulp tissue. As caries-related bacteria invade... 
DNA methylation | Human odontoblast-like cells | DNMT1 | Inflammation | Myeloid differentiation primary response gene 88 | Lipoteichoic acid | ACTIVATION | CYTOKINES | DENTAL-PULP | CANCER | LPS | CELL BIOLOGY | GENES | EPIGENETIC REGULATION | EXPRESSION | Ethylenediaminetetraacetic acid | Dental caries | Epigenetic inheritance | Immune response | Methyltransferases | Genes | Genetic aspects | Genetic transcription | Methylation | Phosphorylation | Transcription | Interleukin 6 | Odontoblasts | Dnmt1 gene | Bacteria | Interleukin 8 | Deoxyribonucleic acid--DNA | Immune system | NF-κB protein | TRAF6 protein | Cytokines | DNMT1 protein | Extracellular signal-regulated kinase | Tubules | MAP kinase | MyD88 protein | DNA methyltransferase | Dental pulp
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10. Full Text DNMT1-mediated PTEN hypermethylation confers hepatic stellate cell activation and liver fibrogenesis in rats
by Bian, Er-Bao and Huang, Cheng and Ma, Tao-Tao and Tao, Hui and Zhang, Hui and Cheng, Chang and Lv, Xiong -Wen and Li, Jun
Toxicology and Applied Pharmacology, ISSN 0041-008X, 10/2012, Volume 264, Issue 1, pp. 13 - 22
Hepatic stellate cell (HSC) activation is an essential event during liver fibrogenesis. Phosphatase and tension homolog deleted on chromosome 10 (PTEN), a... 
DNA methylation | DNA methyltransferase 1 (DNMT1) | Hepatic stellate cell (HSC) | Phosphatase and tension homolog deleted on chromosome 10 (PTEN) | Liver fibrosis | FIBROSIS | PROMOTER HYPERMETHYLATION | SIGNALING PATHWAYS | TGF-BETA | HUMAN CANCER-CELLS | CPG METHYLATION | EPIGENETIC REGULATION | TUMOR-SUPPRESSOR | PHARMACOLOGY & PHARMACY | TOXICOLOGY | EXPRESSION | Cell Line | Promoter Regions, Genetic | Up-Regulation | DNA (Cytosine-5-)-Methyltransferase 1 | Gene Silencing | Hepatic Stellate Cells - metabolism | PTEN Phosphohydrolase - metabolism | Rats | Azacitidine - analogs & derivatives | Male | Phosphatidylinositol 3-Kinases - metabolism | Rats, Sprague-Dawley | Gene Knockdown Techniques | MAP Kinase Signaling System | DNA (Cytosine-5-)-Methyltransferases - metabolism | Azacitidine - pharmacology | DNA (Cytosine-5-)-Methyltransferases - genetics | DNA Methylation | Animals | Liver Cirrhosis, Experimental - pathology | Proto-Oncogene Proteins c-akt - metabolism | Liver diseases | Phosphatases | Methyltransferases | RNA | Liver | Genes | DNA | Genetic transcription | Transforming growth factors | Muscle proteins | Methylation | Index Medicus | DNMT1 protein | Extracellular signal-regulated kinase | stellate cells | AKT protein | Promoters | epigenetics | 1-Phosphatidylinositol 3-kinase | Cell activation | Hepatocytes | chromosome 10 | Fibrosis | Dnmt1 gene | DNA methyltransferase | Tumor suppressor genes | PTEN protein | 5-aza-2'-deoxycytidine | Tumors | METHYLATION | COLLAGEN | ACTIN | NEOPLASMS | TRANSCRIPTION | RATS | CHROMOSOMES | 60 APPLIED LIFE SCIENCES | GROWTH FACTORS | PROMOTERS | DEOXYCYTIDINE | GENES | LIVER | METHYL TRANSFERASES | MUSCLES
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11. Full Text Targeting epigenetic machinery: Emerging novel allosteric inhibitors
by Ye, Fei and Huang, Jing and Wang, Hongbo and Luo, Cheng and Zhao, Kehao
Pharmacology & Therapeutics, ISSN 0163-7258, 09/2019, p. 107406
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12. Full Text HLA DQB1∗06:02 negative narcolepsy with hypocretin/orexin deficiency
by Han, Fang and Lin, Ling and Schormair, Barbara and Pizza, Fabio and Plazzi, Giuseppe and Ollila, Hanna M and Nevsimalova, Sona and Jennum, Poul and Knudsen, Stine and Winkelmann, Juliane and Coquillard, Cristin and Babrzadeh, Farbod and Strom, Tim M and Wang, Chunlin and Mindrinos, Michael and Vina, Marcelo Fernandez and Mignot, Emmanuel
Sleep, ISSN 0161-8105, 10/2014, Volume 37, Issue 10, pp. 1601 - 1608
DNMT1 | MOG | Exome sequencing | MHC | Narcolepsy | HLA | Hypocretin | Orexin | Cataplexy
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13. Full Text Curcumin increases exosomal TCF21 thus suppressing exosomeinduced lung cancer
by Wu, Hao and Zhou, Jingcheng and Zeng, Chao and Wu, Da and Mu, Zhimin and Chen, Baokun and Xie, Yuancai and Ye, Yiwang and Liu, Jixian
Oncotarget, 2016, Volume 7, Issue 52, pp. 87081 - 87090
TCF21 | DNMT1 | Curcumin | Exosome | Lung cancer
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14. Full Text DNA methylation processes in atherosclerotic plaque
by Aavik, Einari and Babu, Mohan and Ylä-Herttuala, Seppo
Atherosclerosis, ISSN 0021-9150, 02/2019, Volume 281, pp. 168 - 179
Underlying mechanisms of cardiovascular diseases (CVD) have been investigated for over 100 years and novel molecular level mechanisms in the pathophysiology... 
DNA methylation | TET2 | Cardiovascular disease | DNMT1 | Atherosclerosis | DNMT3A
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15. Full Text Epigenetic regulation of IncRNA KCNKI5-ASI in gastric cancer
by Zhang, Haiyan and Zhang, Zhuo and Wang, Dayu
Cancer Management and Research, ISSN 1179-1322, 09/2019, Volume 11, pp. 8589 - 8602
Haiyan Zhang,1 Zhuo Zhang,2 Dayu Wang1 1Department of Gastrointestinal Colorectal and Anal Surgery, China-Japan Union Hospital of Jilin University, Changchun,... 
lncRNA KCNK15-AS1 DNMT1 HDAC1 gastric cancer miR-21
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16. miR-148a regulates cardiomyocyte differentiation of mesenchymal stem cells via targeting DNMT1
by Zhang, Wencai and Gong, Junlong and Yang, Fan and Zhao, Luosha
Medical Journal of Wuhan University, ISSN 1671-8852, 01/2019, Volume 40, Issue 1, pp. 11 - 16
DNMT1 | MSCs | MiR-148a | Cardiomyocyte | Differentiation
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17. Full Text 15-Deoxy-Δ12,14-prostaglandin J2 up-regulates the expression of 15-hydroxyprostaglandin dehydrogenase through DNA methyltransferase 1 inactivation
by Jang, Hye-Ok and Lee, Ha-Na and Woo, Jeong-Hwa and Lee, Ja-Young and Kim, Areumnuri and Lee, Jin Kyung and Kim, Do-Hee and Surh, Young-Joon and Na, Hye-Kyung
Free Radical Research, ISSN 1071-5762, 03/2019, Volume 53, Issue 3, pp. 335 - 347
15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is the key enzyme that catalyses the conversion of prostaglandin E 2 to a keto metabolite. The expression of... 
breast cancer | DNMT1 | 15-PGDH | methylation | 15d-PGJ
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18. Full Text Dnmt1 is essential for egg production and embryo viability in the large milkweed bug, Oncopeltus fasciatus 06 Biological Sciences 0604 Genetics
by Bewick, Adam J and Sanchez, Zachary and McKinney, Elizabeth C and Moore, Allen J and Moore, Patricia J and Schmitz, Robert J
Epigenetics and Chromatin, 01/2019, Volume 12, Issue 1
DNA methylation | Dnmt1 | Reproduction | RNAi | Transcription
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19. Full Text Human papillomavirus type 16 E7 oncoprotein mediates CCNA1 promoter methylation
by Chalertpet, Kanwalat and Pakdeechaidan, Watcharapong and Patel, Vyomesh and Mutirangura, Apiwat and Yanatatsaneejit, Pattamawadee
Cancer Science, ISSN 1347-9032, 10/2015, Volume 106, Issue 10, pp. 1333 - 1340
Human papillomavirus ( HPV ) oncoproteins drive distinctive promoter methylation patterns in cancer. However, the underlying mechanism remains to be... 
CCNA1 | Dnmt1 | promoter methylation | cervical cancer | 16‐E7 | HPV | Promoter methylation | HPV 16-E7 | Cervical cancer | HYPERMETHYLATION | PROTEIN | DNA METHYLATION | CERVICAL-CANCER | P53 MUTATION | HEPATOCELLULAR-CARCINOMA | ONCOLOGY | METHYLTRANSFERASE DNMT1 | VIRUS INFECTION | SQUAMOUS-CELL CARCINOMA | GENE-EXPRESSION | DNA (Cytosine-5-)-Methyltransferase 1 | Cyclin A1 - genetics | Humans | Molecular Sequence Data | DNA Methylation - genetics | Uterine Cervical Neoplasms - genetics | Cyclin A1 - biosynthesis | Promoter Regions, Genetic - genetics | Human papillomavirus 16 - metabolism | Papillomavirus E7 Proteins - genetics | DNA (Cytosine-5-)-Methyltransferases - metabolism | Papillomavirus E7 Proteins - metabolism | RNA Interference | Cell Line, Tumor | Female | Oncogene Proteins, Viral - genetics | RNA, Small Interfering | Human papillomavirus 16 - genetics | DNA (Cytosine-5-)-Methyltransferases - biosynthesis | Papillomaviruses | Methyltransferases | Analysis | Genomics | Methylation | Papillomavirus infections | Transformation | DNMT1 protein | Genomes | siRNA | Studies | Human papillomavirus | DNA methylation | Head and neck cancer | DNA methyltransferase | Deoxyribonucleic acid--DNA | Viral infections | Original
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20. Full Text Gene Body Methylation Can Alter Gene Expression and Is a Therapeutic Target in Cancer
by Yang, Xiaojing and Han, Han and De Carvalho, Daniel D and Lay, Fides D and Jones, Peter A and Liang, Gangning
Cancer Cell, ISSN 1535-6108, 10/2014, Volume 26, Issue 4, pp. 577 - 590
DNA methylation in promoters is well known to silence genes and is the presumed therapeutic target of methylation inhibitors. Gene body methylation is... 
DECITABINE | EPIGENOMIC ANALYSIS |