Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (132) 132
humans (117) 117
dock8 (103) 103
immunology (98) 98
immunodeficiency (62) 62
hyper-ige syndrome (61) 61
dock8 deficiency (60) 60
guanine nucleotide exchange factors - genetics (59) 59
mutations (57) 57
mutation (56) 56
female (55) 55
male (52) 52
child (46) 46
dedicator (44) 44
allergy (42) 42
immunoglobulin e (41) 41
job syndrome - genetics (37) 37
allergy and immunology (36) 36
article (35) 35
child, preschool (33) 33
guanine nucleotide exchange factors - deficiency (33) 33
phenotype (32) 32
stat3 (32) 32
abridged index medicus (30) 30
adolescent (29) 29
cytokinesis 8 dock8 (29) 29
job syndrome - immunology (26) 26
stem-cell transplantation (25) 25
t cells (25) 25
animals (24) 24
transplantation (24) 24
combined immunodeficiency (22) 22
deficiency (22) 22
guanine nucleotide exchange factors - immunology (22) 22
infections (22) 22
hematopoietic stem cell transplantation (21) 21
job syndrome - diagnosis (21) 21
pediatrics (21) 21
immunologic deficiency syndromes - immunology (20) 20
infant (20) 20
genetic aspects (19) 19
lymphocytes (19) 19
primary immunodeficiency (19) 19
adult (18) 18
analysis (18) 18
disease (18) 18
health aspects (18) 18
stat3 mutations (18) 18
hyperimmunoglobulin-e syndrome (17) 17
t-lymphocytes - immunology (17) 17
activation (16) 16
atopic dermatitis (16) 16
autoimmunity (16) 16
dock8 mutations (16) 16
patients (16) 16
stat3 transcription factor - genetics (16) 16
t-cells (16) 16
bone-marrow-transplantation (15) 15
eczema (15) 15
guanine nucleotide exchange factors - metabolism (15) 15
immunologic deficiency syndromes - genetics (15) 15
proteins (15) 15
stem cells (15) 15
b-lymphocytes - immunology (14) 14
hematopoietic stem cells (14) 14
immunity (14) 14
survival (14) 14
children (13) 13
diagnosis (13) 13
differentiation (13) 13
genes (13) 13
immunologic deficiency syndromes - therapy (13) 13
internal medicine (13) 13
job syndrome - therapy (13) 13
mice (13) 13
pedigree (13) 13
treatment outcome (13) 13
young adult (13) 13
cdc42 (12) 12
cytokinesis (12) 12
dedicator of cytokinesis 8 (12) 12
dermatitis (12) 12
expression (12) 12
genetics & heredity (12) 12
hyper ige syndrome (12) 12
immune system (12) 12
infectious diseases (12) 12
job syndrome - complications (12) 12
lymphocytes t (12) 12
migration (12) 12
care and treatment (11) 11
disease susceptibility (11) 11
dna mutational analysis (11) 11
flow cytometry (11) 11
food allergy (11) 11
hematology (11) 11
immunoglobulin e - blood (11) 11
medical colleges (11) 11
medicine, research & experimental (11) 11
signal transduction (11) 11
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Phagocyte mayHEME caused by severe hemolysis
by Tan, Sioh-Yang and Weninger, Wolfgang
Nature Immunology, ISSN 1529-2908, 12/2016, Volume 17, Issue 12, pp. 1335 - 1337
Free heme released by hemolysis directly inhibits bacterial phagocytosis by macrophages via alterations of actin cytoskeletal dynamics. 
DOCK8 | IMMUNOLOGY
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells (vol 484, pg 510, 2012)
by Eisenbarth, SC and Williams, A and Colegio, OR and Meng, HL and Strowig, T and Rongvaux, A and Henao-Mejia, J and Thaiss, CA and Joly, S and Gonzalez, DG and Xu, L and Zenewicz, LA and Haberman, AM and Elinav, E and Kleinstein, SH and Sutterwala, FS and Lavell, RAF
NATURE, ISSN 0028-0836, 02/2016, Volume 530, Issue 7591, pp. 504 - 504
RESPONSES | DOCK8 | MULTIDISCIPLINARY SCIENCES | MOUSE
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Hypomorphic function and somatic reversion of DOCK8 cause combined immunodeficiency without hyper-IgE
by Kienzler, Anne-Kathrin and van Schouwenburg, Pauline A and Taylor, John and Marwah, Ishita and Sharma, Richa U and Noakes, Charlotte and Thomson, Kate and Sadler, Ross and Segal, Shelley and Ferry, Berne and Taylor, Jenny C and Blair, Edward and Chapel, Helen and Patel, Smita Y
Clinical Immunology, ISSN 1521-6616, 2015, Volume 163, pp. 17 - 21
Abstract Loss-of-function mutations in DOCK8 are linked to hyper-IgE syndrome. Patients typically present with recurrent sinopulmonary infections, severe... 
Allergy and Immunology | Hyper-IgE syndrome | Phenotypic variability | Combined immunodeficiency | Whole exome sequencing | DOCK8 | CELL CYTOTOXICITY | HEALTHY-CHILDREN | DEDICATOR | PHENOTYPE | SUBSETS | MUTATIONS | IMMUNOLOGY | Recurrence | Guanine Nucleotide Exchange Factors - genetics | Immunologic Deficiency Syndromes - complications | Humans | Bronchiectasis - immunology | Immunoglobulin M - immunology | Immunoglobulin E - immunology | Immunoglobulin G - immunology | Respiratory Tract Infections - immunology | Immunologic Deficiency Syndromes - genetics | Female | Heterozygote | Respiratory Tract Infections - etiology | Mutation | Immunologic Deficiency Syndromes - immunology | Child | Bronchiectasis - etiology | Immunoglobulin E | Immunodeficiency | Index Medicus | EBV, Epstein–Barr-Virus | DHR1 | Mut, Mutated DOCK8 transcript (referring to c.6019dupT) | HC, Healthy control | CFSE, Carboxyfluorescein diacetate, succinimidyl ester | 2, DOCK homology region | PBMC, Peripheral blood mononuclear cell | PHA, Phytohemagglutinin | Pt, Patient | Brief Communication | DOCK8, Dedicator of cytokinesis 8 | Trunc, Truncated DOCK8 protein
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Haploidentical Related Donor Hematopoietic Stem Cell Transplantation for Dedicator-of-Cytokinesis 8 Deficiency Using Post-Transplantation Cyclophosphamide
by Shah, Nirali N and Freeman, Alexandra F and Su, Helen and Cole, Kristen and Parta, Mark and Moutsopoulos, Niki M and Baris, Safa and Karakoc-Aydiner, Elif and Hughes, Thomas E and Kong, Heidi H and Holland, Steve M and Hickstein, Dennis D
Biology of Blood and Marrow Transplantation, ISSN 1083-8791, 2017, Volume 23, Issue 6, pp. 980 - 990
Highlights • Allogeneic transplantation for dedicator-of-cytokinesis 8 (DOCK8) deficiency using haploidentical donors with post-transplantation... 
Hematology, Oncology and Palliative Medicine | Immune reconstitution | Dedicator-of-cytokinesis-8 (DOCK8) deficiency | Haploidentical transplantation | BONE-MARROW-TRANSPLANTATION | CHRONIC GRANULOMATOUS-DISEASE | ALPHA-BETA | IMMUNOLOGY | VERSUS-HOST-DISEASE | NONMALIGNANT DISORDERS | TRANSPLANTATION | HYPER-IGE SYNDROME | COMBINED IMMUNODEFICIENCY | DOCK8 DEFICIENCY | HEMATOLOGY | HEMATOLOGIC MALIGNANCIES | BLOOD | Immunologic Deficiency Syndromes - therapy | Humans | Survival Rate | Treatment Outcome | Hematopoietic Stem Cell Transplantation - mortality | Transplantation, Haploidentical - mortality | Cyclophosphamide - therapeutic use | Transplantation, Haploidentical - methods | Immunologic Deficiency Syndromes - mortality | Graft vs Host Disease - prevention & control | Hematopoietic Stem Cell Transplantation - methods | Transplantation Conditioning - methods | Guanine Nucleotide Exchange Factors - deficiency | Cyclophosphamide | Transplantation | Hematopoietic stem cells | Stem cells | Usage | Bone marrow | Mycophenolate mofetil | Index Medicus | Dedicator-of-cytokinesis-8 | (DOCK8) deficiency
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text IL-21 alleviates allergic asthma in DOCK8-knockout mice
by Wu, Jiabin and Zhang, Liang and Zhang, Suqian and Qin, Tao and Jiang, Jinqiu and Liu, Qiao and Zhao, Xiaodong and Dai, Jihong
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 06/2018, Volume 501, Issue 1, pp. 92 - 99
Patients with DOCK8 deficiency are at increased susceptibility to develop allergic diseases such as food allergy and asthma. Here, we aimed to analyze the... 
Allergic asthma | Ovalbumin | DOCK8 gene | IL-21 | Murine model | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text IL-21 alleviates allergic asthma in DOCK8-knockout mice
by Wu, JB and Zhang, SQ and Qin, T and Jiang, JQ and Liu, Q and Zhang, L and Zhao, XD and Dai, JH
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ISSN 0006-291X, 06/2018, Volume 501, Issue 1, pp. 92 - 99
Patients with DOCK8 deficiency are at increased susceptibility to develop allergic diseases such as food allergy and asthma. Here, we aimed to analyze the... 
Allergic asthma | Ovalbumin | BIOCHEMISTRY & MOLECULAR BIOLOGY | GRASS-POLLEN | INTERLEUKIN-21 | IL-21 | HYPER-IGE SYNDROME | B-CELLS | BIOPHYSICS | DEDICATOR | DOCK8 gene | IMMUNE-RESPONSES | ENHANCEMENT | DIFFERENTIATION | T-CELLS | Murine model | CYTOKINESIS 8 DOCK8
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Large deletions and point mutations involving the dedicator of cytokinesis 8 (DOCK8) in the autosomal-recessive form of hyper-IgE syndrome
by Engelhardt, Karin R., Dr and McGhee, Sean, MD and Winkler, Sabine, MSc and Sassi, Atfa, PhD and Woellner, Cristina, MSc and Lopez-Herrera, Gabriela, PhD and Chen, Andrew and Kim, Hong Sook, PhD and Lloret, Maria Garcia, MD and Schulze, Ilka, MD and Ehl, Stephan, MD and Thiel, Jens, MD and Pfeifer, Dietmar, Dr and Veelken, Hendrik, MD and Niehues, Tim, MD and Siepermann, Kathrin, MD and Weinspach, Sebastian, MD and Reisli, Ismail, MD and Keles, Sevgi, MD and Genel, Ferah, MD and Kutuculer, Necil, MD and Camcoğlu, Yldz, MD and Somer, Ayper, MD and Karakoc-Aydiner, Elif, MD and Barlan, Isil, MD and Gennery, Andrew, MD and Metin, Ayse, MD, PhD and Degerliyurt, Aydan, MD and Pietrogrande, Maria C., MD and Yeganeh, Mehdi, MD and Baz, Zeina, MD and Al-Tamemi, Salem, MD and Klein, Christoph, MD, PhD and Puck, Jennifer M., MD and Holland, Steven M., MD and McCabe, Edward R.B., MD, PhD and Grimbacher, Bodo, MD and Chatila, Talal A., MD, MSc
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2009, Volume 124, Issue 6, pp. 1289 - 1302.e4
Background The genetic etiologies of the hyper-IgE syndromes are diverse. Approximately 60% to 70% of patients with hyper-IgE syndrome have dominant mutations... 
Allergy and Immunology | recurrent infection | genomic deletions | human gene mutation | molluscum contagiosum | T H17 cells | Autosomal recessive hyper-IgE syndrome | DOCK8 | primary immunodeficiency | eosinophils | T cells | copy number variations | IgE regulation | 17 cells | IMMUNOLOGY | IDENTIFICATION | REARRANGEMENTS | GENOME | ALLERGY | T(H)17 cells | Job Syndrome - immunology | Sequence Deletion | Genome-Wide Association Study | Guanine Nucleotide Exchange Factors - genetics | Job Syndrome - genetics | Humans | Child, Preschool | Male | Genes, Recessive | Haplotypes - genetics | Homozygote | Point Mutation | Lymphocyte Activation - genetics | Lymphocyte Activation - immunology | Pedigree | Female | T-Lymphocytes - immunology | Job Syndrome - pathology | Polymorphism, Single Nucleotide | Child | Allergy | Medical colleges | Asthma in children | Immunodeficiency | Immunoglobulin E | College teachers | Allergic reaction | Purines | Gene mutations | Genetic research | Genetic aspects | Children | Health aspects | Human genetics | Haplotypes | Cytomegalovirus | Genes | Families & family life | Zebrafish | Genomes | Mutation | Kinases | Chromosomes | Patients | Deoxyribonucleic acid--DNA | Methods | Index Medicus | Abridged Index Medicus | Life Sciences
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Diagnosis of DOCK8 deficiency using Flow cytometry Biomarkers: an Egyptian Center experience
by Meshaal, Safa S and El Hawary, Rabab E and Eldash, Alia and Grimbacher, Bodo and Camacho-Ordonez, Nadezhda and Abd Elaziz, Dalia S and Galal, Nermeen M and Boutros, Jeannette A and Shawky, Shereen M and Elmarsafy, Aisha M
Clinical Immunology, ISSN 1521-6616, 10/2018, Volume 195, pp. 36 - 44
In the past few years, several genes were shown to be implicated in various forms of the Hyper Immunoglobulin E syndrome. The present study is the first to... 
pSTAT3 | Flow cytometry | AR-HIES | Th17 | DOCK8 | DOCKS | PHENOTYPE | IMMUNOLOGY | REFERENCE VALUES | ACTIVATOR | DEDICATOR | DISEASE | PROTEINS | CYTOKINESIS 8 DOCK8 | Immunoglobulin E | Medicine, Experimental | Medical research | B cells | Analysis | Immunodeficiency
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Vaccine Strain Varicella Zoster-Induced CNS Vasculopathy as the Presenting Feature of DOCK8 Deficiency
by Sabry, Angela and Hauk, Pia J and Jing, Huie and Su, Helen C and Stence, Nicholas V and Mirsky, David M and Nagel, Maria A and Abbott, Jordan K and Dragone, Leonard L and Armstrong-Wells, Jennifer and Curtis, Donna J and Cohrs, Randall and Schmid, D. Scott and Gilden, Don and Gelfand, Erwin W
The Journal of allergy and clinical immunology, ISSN 0091-6749, 4/2014, Volume 133, Issue 4, pp. 1225 - 1227
atopy | CNS vasculopathy | varicella zoster | DOCK8
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Haploidentical stem cell transplantation in DOCK8 deficiency-Successful control of pre-existing severe viremia with a TCRa beta/CD19-depleted graft and antiviral treatment
by Ghosh, S and Schuster, FR and Adams, O and Babor, F and Borkhardt, A and Comoli, P and Handgretinger, R and Lang, P and Laws, HJ and Siepermann, M and Meisel, R
CLINICAL IMMUNOLOGY, ISSN 1521-6616, 05/2014, Volume 152, Issue 1-2, pp. 111 - 114
Hyper IgE | DOCK8 deficiency | IMMUNOLOGY | HSCT | RECONSTITUTION | Primary immunodeficiency
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Food Allergies Can Persist After Myeloablative Hematopoietic Stem Cell Transplantation in DOCK8-Deficient Patients
by Happel, Corinne S and Stone, Kelly D and Freeman, Alexandra F and Shah, Nirali N and Wang, Angela and Lyons, Jonathan J and Guerrerio, Pamela A and Hickstein, Dennis D and Su, Helen C
The Journal of allergy and clinical immunology, ISSN 0091-6749, 6/2016, Volume 137, Issue 6, pp. 1895 - 1898.e5
food allergy | hematopoietic stem cell transplantation (HSCT) | DOCK8 | IgE
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Hematopoietic Stem Cell Transplant for a New Primary Immunodeficiency Disorder: A Voyage Where No Transplant Physician Has Gone Before
by Connelly, James A
Biology of Blood and Marrow Transplantation, ISSN 1083-8791, 2017, Volume 23, Issue 6, pp. 863 - 864
Hematology, Oncology and Palliative Medicine | DOCK8 | Haploidentical hematopoietic stem cell transplant | Immunodeficiency | HYPER-IGE SYNDROME | DEDICATOR | DOCK8 DEFICIENCY | PHENOTYPE | MUTATIONS | IMMUNOLOGY | HEMATOLOGY | TRANSPLANTATION | Hematopoietic Stem Cell Transplantation | Cyclophosphamide | Immunologic Deficiency Syndromes | Cytokinesis | Humans | Transplantation | Hematopoietic stem cells | Stem cells | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Curative treatment of autosomal-recessive hyper-IgE syndrome by hematopoietic cell transplantation
by Gatz, S.A and Benninghoff, U and Schütz, C and Schulz, A and Hönig, M and Pannicke, U and Holzmann, K.-H and Schwarz, K and Friedrich, W
Bone Marrow Transplantation, ISSN 0268-3369, 04/2011, Volume 46, Issue 4, pp. 552 - 556
Autosomal-recessive hyper-IgE syndrome (AR-HIES) is a combined immunodeficiency recently found to be associated with mutations of DOCK8. Clinically, this... 
DOCK8 mutations | hematopoietic cell transplantation | hyper-IgE syndrome | ONCOLOGY | DOCK8 | MUTATIONS | IMMUNOLOGY | HEMATOLOGY | TRANSPLANTATION | Molluscum Contagiosum - therapy | Guanine Nucleotide Exchange Factors - genetics | Job Syndrome - complications | Job Syndrome - therapy | Humans | Adolescent | Molluscum Contagiosum - etiology | Treatment Outcome | Hematopoietic Stem Cell Transplantation - methods | Child | Remission Induction | Index Medicus | Age
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
14. Full Text Quantitative profiling of cytokines and chemokines in DOCK8‐deficient and atopic dermatitis patients
by Jacob, Minnie and Bin Khalaf, Duaa and Alhissi, Safa and Arnout, Rand and Alsaud, Bander and Al‐Mousa, Hamoud and Lopata, Andreas L and Alazami, Anas M and Dasouki, Majed and Abdel Rahman, Anas M
Allergy, ISSN 0105-4538, 02/2019, Volume 74, Issue 2, pp. 370 - 379
Background Hyper-IgE syndromes (HIES) are a clinically overlapping, heterogeneous group of inborn errors of immunity characterized by elevated serum IgE level,... 
hyper‐IgE syndrome | CXCL | atopic dermatitis | DOCK | epidermal growth factor | CXCL10 | hyper-IgE syndrome | DOCK8 | COLONY-STIMULATING FACTOR | IMMUNOLOGY | IP-10 | CANCER | PATHOGENESIS | DEDICATOR | ALLERGY | INFLAMMATION | GROWTH | DOCK8 DEFICIENCY | T-CELLS | INSIGHTS | Therapy | Profiling | Syngeneic grafts | Bone marrow transplantation | Immunoglobulin E | Transplantation | Infections | Pruritus | Dermatitis | Immunity | Subgroups | Proteins | Epidermal growth factor | Atopic dermatitis | Bone marrow | Bioindicators | Growth factors | Cytokines | Inflammation | Protein deficiency | Patients | Eosinophilia | Allergies | Tumor necrosis factor | CXCL10 protein | Biomarkers | Sampling methods | Chemokines | Cancer
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
15. Full Text DOCK8 mutation diagnosed using whole-exome sequencing of the dried blood spot-derived DNA: a case report of an Iraqi girl diagnosed in Japan
by Al-Kzayer, LFY and Al-Aradi, HMH and Shigemura, T and Sano, K and Tanaka, M and Hamada, M and Ali, KH and Aldaghir, OM and Nakazawa, Y and Okuno, Y
BMC MEDICAL GENETICS, ISSN 1471-2350, 06/2019, Volume 20, Issue 1, pp. 114 - 114
BackgroundDedicator of cytokinesis 8 (DOCK8) deficiency (MIM #243700) is a rare disease, leads to a combined primary immunodeficiency (PID), and accounts for... 
Hyper immunoglobulin E syndrome (HIES) | Lymphoproliferative disease (LPD) | Dried blood spots | PHENOTYPE | Flinders technology associates (FTA) cards | DEFICIENCY | Consanguineous marriages | DEDICATOR | DOCK8 deficiency | Whole exome sequencing (WES) | GENETICS & HEREDITY | Iraq | LEUKEMIA | Primary immune deficiency (PID) | CYTOKINESIS 8 DOCK8 | Rare diseases | Usage | Gene mutations | Exome sequencing | Immunoglobulin E | Genetic aspects | Research | Diagnosis | Genetic transcription
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
16. Full Text Diagnostic approach to the hyper-IgE syndromes: Immunologic and clinical key findings to differentiate hyper-IgE syndromes from atopic dermatitis
by Schimke, Lena F., MD and Sawalle-Belohradsky, Julie and Roesler, Joachim, MD and Wollenberg, Andreas, MD and Rack, Anita, MD and Borte, Michael, MD and Rieber, Nikolaus, MD and Cremer, Reinhold, MD and Maaß, Eberhart, MD and Dopfer, Roland, MD and Reichenbach, Janine, MD and Wahn, Volker, MD and Hoenig, Manfred, MD and Jansson, Annette F., MD and Roesen-Wolff, Angela, MD and Schaub, Bianca, MD and Seger, Reinhard, MD and Hill, Harry R., MD and Ochs, Hans D., MD and Torgerson, Troy R., MD, PhD and Belohradsky, Bernd H., MD and Renner, Ellen D., MD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2010, Volume 126, Issue 3, pp. 611 - 617.e1
Background Hyper-IgE syndromes (HIES) are primary immunodeficiency disorders characterized by Staphylococcus aureus abscesses, recurrent pneumonia, increased... 
Allergy and Immunology | dedicator of cytogenesis 8 protein (DOCK8) | Atopic dermatitis | signal transducer and activator of transcription 3 (STAT3) | Job syndrome | tyrosine kinase 2 (TYK2) | hyper-IgE syndrome | National Institutes of Health score | TH17 cells | 17 cells | STAT3 MUTATIONS | JOBS-SYNDROME | DOCK8 | SUSCEPTIBILITY | IMMUNOLOGY | DEFICIENCY | FUNGAL-INFECTIONS | ALLERGY | T(H)17 cells | T-CELLS | TH17 CELLS | Job Syndrome - immunology | Dermatitis, Atopic - genetics | Job Syndrome - diagnosis | Humans | Middle Aged | Child, Preschool | Infant | Male | Dermatitis, Atopic - diagnosis | Interleukin-17 - metabolism | T-Lymphocytes, Helper-Inducer - immunology | Gene Deletion | Adolescent | Dermatitis, Atopic - immunology | T-Lymphocytes, Helper-Inducer - cytology | Adult | Female | Child | STAT3 Transcription Factor - genetics | Tyrosine | Medical colleges | Medical research | Pneumonia | Bacterial pneumonia | Abscess | Staphylococcus aureus infections | Immunodeficiency | Medicine, Experimental | Immunoglobulin E | Diagnosis | Mutation | Dermatitis | Allergies | Viral infections | Eczema | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
17. Full Text DOCK8 Regulates STAT3 Activation and Promotes Th17 Cell Differentiation
by Keles, Sevgi and Charbonnier, Louis Marie and Kabaleeswaran, Venkataraman and Reisli, Ismail and Genel, Ferah and Gulez, Nesrin and Al-Herz, Waleed and Ramesh, Narayanaswamy and Perez-Atayde, Antonio and Eeder, Neslihan Karaca and Kutukculer, Necil and Wu, Hao and Geha, Raif S and Chatila, Talal A
The Journal of allergy and clinical immunology, ISSN 0091-6749, 11/2016, Volume 138, Issue 5, pp. 1384 - 1394.e2
SOCS3 | Hyper IgE Syndrome | DOCK8 | Mucocutaneous Candidiasis | STAT3 | Th17 | Cdc42 | Guanine Nucleotide Exchange Factor
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
18. Full Text Clinical, Immunological and Molecular Characterization of DOCK8 and DOCK8-like Deficient Patients: Single Center Experience of Twenty Five Patients
by Alsum, Zobaida and Hawwari, Abbas and Alsmadi, Osama and Al-Hissi, Safa and Borrero, Esteban and Abu-staiteh, Asma’ and Khalak, Hanif G and Wakil, Salma and Eldali, Abdelmoneim M and Arnaout, Rand and Al-ghonaium, Abdulaziz and Al-Muhsen, Saleh and Al-Dhekri, Hasan and Al-Saud, Bandar and Al-Mousa, Hamoud
Journal of Clinical Immunology, ISSN 0271-9142, 1/2013, Volume 33, Issue 1, pp. 55 - 67
Autosomal recessive hyper-IgE syndrome is a rare combined immunodeficiency characterized by susceptibility to viral infections, atopic eczema, high serum IgE... 
Medical Microbiology | Biomedicine | Immunology | Saudi | DOCK8 | Infectious Diseases | Internal Medicine | immunodeficiency | hyper-IgE syndrome | Hyper-IgE syndrome | Immunodeficiency | DEDICATOR | MUTATIONS | IMMUNOLOGY | STEM-CELL TRANSPLANTATION | CYTOKINESIS 8 DOCK8 | Job Syndrome - immunology | Guanine Nucleotide Exchange Factors - genetics | Job Syndrome - genetics | Humans | Child, Preschool | Male | Secondary Prevention | Immunoglobulin E - blood | Incidence | Job Syndrome - epidemiology | Hospitals, Special | Gene Deletion | Immunoglobulin E - adverse effects | Adolescent | Female | Child | Saudi Arabia - epidemiology | Codon, Nonsense - genetics | Genes, Recessive - immunology | Guanine Nucleotide Exchange Factors - deficiency | Guanine Nucleotide Exchange Factors - chemistry | Virus diseases | Medical colleges | Mortality | Immunoglobulin E | Development and progression | Cytomegalovirus infections | Chemical properties | T cells | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
19. Full Text Multiplexed detection of DOCK8, PGM3 and STAT3 proteins for the diagnosis of Hyper-Immunoglobulin E syndrome using gold nanoparticles-based immunosensor array platform
by Eissa, Shimaa and Abdulkarim, Haya and Dasouki, Majed and Al Mousa, Hamoud and Arnout, Rand and Al Saud, Bandar and Rahman, Anas Abdel and Zourob, Mohammed
Biosensors and Bioelectronics, ISSN 0956-5663, 10/2018, Volume 117, pp. 613 - 619
Multiplexed biosensors hold great promise for early diagnosis of diseases where the detection of multiple biomarkers is required. Hyper Immunoglobulin E... 
Signal transducer and activator of transcription 3 (STAT3) | Phosphoglucomutase 3 (PGM3) | Dedicator of cytokinesis 8 (DOCK8) | Biosensor | Multiplex detection | ELECTROCHEMISTRY | CHEMISTRY, ANALYTICAL | NANOSCIENCE & NANOTECHNOLOGY | ELECTROCHEMICAL BIOSENSOR | CLINICAL-FEATURES | DEFICIENCY | ATOPIC-DERMATITIS | IGE SYNDROME | BIOPHYSICS | DEDICATOR | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | DISEASE | MUTATIONS | CYTOKINESIS 8 DOCK8 | Blood Chemical Analysis - methods | Gold - chemistry | Phosphoglucomutase - blood | Job Syndrome - diagnosis | Guanine Nucleotide Exchange Factors - blood | Humans | Metal Nanoparticles - chemistry | Biosensing Techniques - instrumentation | Biosensing Techniques - methods | Job Syndrome - blood | Blood Chemical Analysis - instrumentation | STAT3 Transcription Factor - blood | Proteins | Nanoparticles | Electrochemical reactions | Detectors | Immunoglobulin E | Cystic fibrosis | Electric properties | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights