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1. Full Text Antibiotic Prophylaxis in Hip Fracture Surgery: A Metaanalysis
by Southwell-Keely, James P and Russo, Robert R and March, Lyn and Cumming, Robert and Cameron, Ian and Brnabic, Alan J. M
Clinical Orthopaedics and Related Research, ISSN 0009-921X, 2004, Volume 419, Issue 419, pp. 179 - 184
A metaanalysis was done to identify the most effective prophylactic antibiotic regimen in hip fracture surgery. Specific comparisons addressed were antibiotics... 
Hip Fractures - surgery | Fracture Fixation, Internal - adverse effects | Follow-Up Studies | Risk Assessment | Humans | Middle Aged | Fracture Fixation, Internal - methods | Male | Reference Values | Treatment Outcome | Antibiotic Prophylaxis | Randomized Controlled Trials as Topic | Dose-Response Relationship, Drug | Surgical Wound Infection - prevention & control | Anti-Bacterial Agents - therapeutic use | Aged, 80 and over | Female | Aged | Infusions, Intravenous | Preoperative Care - methods
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2. Full Text Nonsteroidal antiinflammatory drug use and lung cancer: A metaanalysis
by Khuder, Sadik A and Herial, Nabeel A and Mutgi, Anand B and Federman, Douglas J
Chest, ISSN 0012-3692, 2005, Volume 127, Issue 3, pp. 748 - 754
Study objective: Studies done both in laboratory animals and humans suggest that nonsteroidal antiinflammatory drug (NSAID) use may reduce the risk of... 
Aspirin | Lung cancer | Metaanalysis | Nonsteroidal antiinflammatory drug | Smoking | metaanalysis | COX-2 | nonsteroidal antiinflammatory drug | PREVENTION | RISK | lung cancer | BREAST-CANCER | CIGARETTE-SMOKING | LOW-DOSE ASPIRIN | RESPIRATORY SYSTEM | smoking | CYCLOOXYGENASE-2 INHIBITORS | TOBACCO-SMOKE | aspirin | EXPRESSION | CARCINOMA | CRITICAL CARE MEDICINE | Dose-Response Relationship, Drug | Risk | Lung Neoplasms - prevention & control | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Humans | Dosage and administration | Nonsteroidal anti-inflammatory drugs | Drug therapy | Risk factors
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3. Full Text Tumor necrosis factor alpha drugs in rheumatoid arthritis: Systematic review and metaanalysis of efficacy and safety
by Alonso-Ruiz, Alberto and Pijoan, Jose Ignacio and Ansuategui, Eukene and Urkaregi, Arantxa and Calabozo, Marcelo and Quintana, Antonio
BMC Musculoskeletal Disorders, ISSN 1471-2474, 2008, Volume 9, Issue 1, pp. 52 - 52
Background: To analyse available evidence on the efficacy and safety of anti-TNF alpha drugs (infliximab, etanercept and adalimumab) for treating rheumatoid... 
DOSE METHOTREXATE | COMBINATION THERAPY | JOINT DAMAGE | BLOCKING-AGENTS | DOUBLE-BLIND | FUSION PROTEIN | PLUS METHOTREXATE | RECEIVING CONCOMITANT METHOTREXATE | MONOCLONAL-ANTIBODY | RHEUMATOLOGY | ETANERCEPT | ORTHOPEDICS | Humans | Immunoglobulin G - therapeutic use | Antibodies, Monoclonal - therapeutic use | Treatment Outcome | Methotrexate - therapeutic use | Receptors, Tumor Necrosis Factor - therapeutic use | Dose-Response Relationship, Drug | Antibodies, Monoclonal, Humanized | Tumor Necrosis Factor-alpha - therapeutic use | Etanercept | Infliximab | Arthritis, Rheumatoid - drug therapy | Adalimumab | Antirheumatic Agents - therapeutic use | Antirheumatic agents | Tumor necrosis factor | Rheumatoid arthritis | Dosage and administration | Diagnosis | Research | Drug therapy | Health aspects
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4. Full Text Coffee consumption and risk of breast cancer: a metaanalysis
by Tang, Naping, MD and Zhou, Bo, MD and Wang, Bin, PhD and Yu, Rongbin, PhD
American Journal of Obstetrics and Gynecology, ISSN 0002-9378, 2009, Volume 200, Issue 3, pp. 290.e1 - 290.e9
Objective This metaanalysis was conducted to assess the association between coffee consumption and breast cancer risk. Study Design Relevant studies were... 
Obstetrics and Gynecology | breast cancer | coffee consumption | metaanalysis | CAFFEINE CONSUMPTION | LIFE-STYLE FACTORS | PLASMA ENTEROLACTONE | CYCLIC-NUCLEOTIDES | TREND ESTIMATION | OBSTETRICS & GYNECOLOGY | DOSE-RESPONSE DATA | GREEN TEA | DIETARY FACTORS | BRCA1 MUTATION CARRIERS | FIBROCYSTIC DISEASE | Central Nervous System Stimulants - adverse effects | Humans | Risk Factors | Caffeine - adverse effects | Female | Coffee - adverse effects | Case-Control Studies | Breast Neoplasms - epidemiology | Cohort Studies | Care and treatment | Oncology, Experimental | Breast cancer | Research | Coffee | Health aspects | Risk factors | Cancer | Index Medicus | Abridged Index Medicus
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5. Full Text Use of antibiotics for the treatment of preterm parturition and prevention of neonatal morbidity: a metaanalysis
by Hutzal, Carolyn E., MD and Boyle, Elaine M., MD and Kenyon, Sara L., MA and Nash, Jennifer V., BHSc and Winsor, Stephanie, MD and Taylor, David J., MD and Kirpalani, Haresh, BM, MSc
American Journal of Obstetrics and Gynecology, ISSN 0002-9378, 2008, Volume 199, Issue 6, pp. 620.e1 - 620.e8
Objective We conducted a metaanalysis to determine whether antibiotics prolong pregnancy and reduce neonatal morbidity in preterm premature rupture of... 
Obstetrics and Gynecology | prolonged rupture of membranes | preterm labor | neonatal outcomes | metaanalysis | antibiotics | ANTIMICROBIAL THERAPY | BRAIN-INJURY | RANDOMIZED CONTROLLED-TRIAL | DEVELOPMENTAL-DISABILITY | BROAD-SPECTRUM ANTIBIOTICS | OBSTETRICS & GYNECOLOGY | BRONCHOPULMONARY DYSPLASIA | PREMATURE RUPTURE | DOUBLE-BLIND | PLACEBO-CONTROLLED TRIAL | INTACT MEMBRANES | Infant, Premature, Diseases - prevention & control | Drug Administration Schedule | Follow-Up Studies | Humans | Probability | Reference Values | Treatment Outcome | Fetal Membranes, Premature Rupture - prevention & control | Pregnancy Trimester, Third | Randomized Controlled Trials as Topic | Dose-Response Relationship, Drug | Pregnancy | Young Adult | Obstetric Labor, Premature - drug therapy | Infant, Premature | Adult | Female | Anti-Bacterial Agents - administration & dosage | Obstetric Labor, Premature - prevention & control | Fetal Membranes, Premature Rupture - drug therapy | Infant Mortality - trends | Infant, Newborn | Pregnancy Outcome | Infants (Newborn) | Prevention | Usage | Oncology, Experimental | Universities and colleges | Research | Morbidity | Cancer
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6. Full Text Dose-response relationship of mannitol and intracranial pressure: A metaanalysis
by Sorani, Marco D and Manley, Geoffrey T
Journal of Neurosurgery, ISSN 0022-3085, 01/2008, Volume 108, Issue 1, pp. 80 - 87
Object. Brain edema can increase intracranial pressure (ICP), potentially leading to ischemia, herniation, and death. Edema and elevated ICP are often treated... 
Edema | Intracranial pressure | Dose | Mannitol | Metaanalysis | SURGERY | metaanalysis | SODIUM-CHLORIDE | MANAGEMENT | edema | BRAIN-INJURY | HEAD-INJURED PATIENTS | RANDOMIZED-TRIAL | mannitol | CLINICAL NEUROLOGY | STROKE | dose | intracranial pressure | HYPERTENSION | 20-PERCENT MANNITOL | HYPERTONIC SALINE | BLOOD | Dose-Response Relationship, Drug | Intracranial Pressure - drug effects | Drug Administration Schedule | Humans | Mannitol - administration & dosage | Diuretics, Osmotic - administration & dosage | Diuretics, Osmotic - pharmacology | Mannitol - pharmacology
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7. Full Text The Effect of Growth Hormone Replacement on Exercise Capacity in Patients with GH Deficiency: A Metaanalysis
by Widdowson, W. Matthew and Gibney, James
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 11/2008, Volume 93, Issue 11, pp. 4413 - 4417
Context/Objectives: GH replacement in GH-deficient adults exerts clear effects on body composition, but there is a lack of high-quality evidence concerning its... 
ADULT PATIENTS | SUBSTITUTION | HYPOPITUITARY ADULTS | THERAPY | ENDOCRINOLOGY & METABOLISM | PHYSICAL PERFORMANCE | BODY-COMPOSITION | NORMALIZATION | LIPIDS | Hypopituitarism - physiopathology | Double-Blind Method | Humans | Exercise Tolerance - drug effects | Hormone Replacement Therapy | Growth Hormone - deficiency | Randomized Controlled Trials as Topic | Cross-Over Studies | Dose-Response Relationship, Drug | Heart Rate - drug effects | Body Composition - drug effects | Growth Hormone - therapeutic use | Oxygen Consumption - drug effects | Exercise Tolerance - physiology | Placebos | Adult | Exercise - physiology | Research Design | Hypopituitarism - drug therapy
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8. Full Text Impact of Growth Hormone (GH) Treatment on Cardiovascular Risk Factors in GH-Deficient Adults: A Metaanalysis of Blinded, Randomized, Placebo-Controlled Trials
by Maison, Patrick and Griffin, Simon and Nicoue-Beglah, Marc and Haddad, Nabila and Balkau, Beverley and Chanson, Philippe and Metaanalysis of Blinded, Randomized, Placebo-Controlled Trials
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 05/2004, Volume 89, Issue 5, pp. 2192 - 2199
Patients with hypopituitarism have an increased risk of cardiovascular mortality. GH treatment could modify the cardiovascular risk in adults with GH... 
LIPOPROTEIN(A) | PREMATURE MORTALITY | HYPOPITUITARY ADULTS | SERUM-LIPIDS | PROTEIN-METABOLISM | ENDOCRINOLOGY & METABOLISM | REPLACEMENT THERAPY | BODY-MASS INDEX | GENDER | INSULIN SENSITIVITY | LIFE EXPECTANCY | Blood Pressure | Body Composition | Cardiovascular Diseases - etiology | Blood Glucose - analysis | Double-Blind Method | Drug Administration Schedule | Humans | Middle Aged | Risk Factors | Human Growth Hormone - deficiency | Male | Insulin - blood | Randomized Controlled Trials as Topic | Dose-Response Relationship, Drug | Growth Hormone - therapeutic use | Lipids - blood | Placebos | Adult | Female | Aged | Metabolism, Inborn Errors - drug therapy | Metabolism, Inborn Errors - complications | Metabolism, Inborn Errors - physiopathology
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9. Full Text Tea consumption and risk of endometrial cancer: a metaanalysis
by Tang, Na-Ping, MD and Li, Hua, MD and Qiu, Yun-Liang, MD and Zhou, Guo-Min, PhD and Ma, Jing, PhD
American Journal of Obstetrics and Gynecology, ISSN 0002-9378, 2009, Volume 201, Issue 6, pp. 605.e1 - 605.e8
Objective The objective of the study was to assess the association between tea consumption and endometrial cancer. Study Design Studies were identified by... 
Obstetrics and Gynecology | endometrial cancer | metaanalysis | tea consumption | COFFEE CONSUMPTION | TREND ESTIMATION | OBSTETRICS & GYNECOLOGY | DOSE-RESPONSE DATA | SOY FOOD | GREEN TEA | POLYPHENOLS | BLACK TEA | POSTMENOPAUSAL WOMEN | ASSOCIATION | EPIGALLOCATECHIN-3-GALLATE | Tea | Endometrial Neoplasms - genetics | Humans | Risk Factors | Female | Beverages | Case-Control Studies | Endometrial Neoplasms - prevention & control | Cohort Studies | Care and treatment | Endometrial cancer | Oncology, Experimental | Research | Health aspects | Risk factors | Cancer
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10. Full Text Metaanalysis of Randomized Trials of the Efficacy and Safety of Donepezil, Galantamine, and Rivastigmine for the Treatment of Alzheimer Disease
by Ritchie, Craig W and Ames, David and Clayton, Tim and Lai, Rosalind
The American Journal of Geriatric Psychiatry, ISSN 1064-7481, 07/2004, Volume 12, Issue 4, pp. 358 - 369
The authors estimated the effects of each of the three commonly used drugs for Alzheimer disease (donepezil, galantamine, and rivastigmine) in terms of... 
MODERATE | MULTICENTER | DEMENTIA | GLOBAL FUNCTION | PSYCHIATRY | TOLERABILITY | DOUBLE-BLIND | 1-YEAR | GERONTOLOGY | 24-WEEK | PLACEBO-CONTROLLED TRIAL | GERIATRICS & GERONTOLOGY | Indans - adverse effects | Piperidines - administration & dosage | Humans | Phenylcarbamates | Alzheimer Disease - drug therapy | Treatment Outcome | Carbamates - administration & dosage | Galantamine - administration & dosage | Indans - therapeutic use | Randomized Controlled Trials as Topic | Dose-Response Relationship, Drug | Cholinesterase Inhibitors - administration & dosage | Galantamine - therapeutic use | Piperidines - therapeutic use | Rivastigmine | Piperidines - adverse effects | Cholinesterase Inhibitors - adverse effects | Carbamates - adverse effects | Galantamine - adverse effects | Indans - administration & dosage | Carbamates - therapeutic use | Cholinesterase Inhibitors - therapeutic use
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11. Full Text Less is More: Patient-Level Metaanalysis Reveals Paradoxical Dose-Response Effects of a Computer-Based Social Anxiety Intervention Targeting Attentional Bias
by Price, Rebecca B and Kuckertz, Jennie M and Amir, Nader and Bar-Haim, Yair and Carlbring, Per and Wallace, Meredith L
Depression and anxiety, ISSN 1091-4269, 12/2017, Volume 34, Issue 12, pp. 1106 - 1115
dose-response | attention training | attention bias modification | social anxiety | patient-level meta-analysis
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12. Full Text Smoking increases risks of all-cause and breast cancer specific mortality in breast cancer individuals: A dose-response metaanalysis of prospective cohort studies involving 39725 breast cancer cases
by Wang, Kang and Li, Feng and Zhang, Xiang and Li, Zhuyue and Li, Hongyuan
Oncotarget, 2016, Volume 7, Issue 50, pp. 83134 - 83147
Smoking is associated with the risks of mortality from breast cancer (BC) or all causes in BC survivors. Two-stage dose-response meta-analysis was conducted. A... 
Breast cancer specific mortality | Dose-response | All-cause mortality | Breast cancer survival | Smoking | PROSTATE | LIFE-STYLE FACTORS | DIAGNOSIS | STATISTICS | breast cancer survival | BEHAVIOR | CELL BIOLOGY | WOMEN | CIGARETTE-SMOKING | smoking | all-cause mortality | dose-response | breast cancer specific mortality | HEALTH | ASSOCIATION | SURVIVORS
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13. Full Text Folic acid supplementation for the prevention of recurrence of colorectal adenomas: metaanalysis of interventional trials
by Ibrahim, Ezzeldin M and Ibrahim, Ezzeldin M and Zekri, Jamal M and Zekri, Jamal M
Medical Oncology, ISSN 1357-0560, 9/2010, Volume 27, Issue 3, pp. 915 - 918
Conflicting data have emerged from preclinical and clinical studies that examined the relationship between folic acid and the risk of recurrence of colorectal... 
Prevention | Pathology | Colorectal adenoma | Medicine & Public Health | Hematology | Colorectal cancer | Internal Medicine | Oncology | Folic acid | CANCER RISK | BIAS | FOLATE SUPPLEMENTATION | COLONIC POLYPS | ALCOHOL | ONCOLOGY | DIETARY-FOLATE | CONSUMPTION | INSTRUMENTS | Colorectal Neoplasms - epidemiology | Intestinal Polyps - epidemiology | Recurrence | Randomized Controlled Trials as Topic - statistics & numerical data | Folic Acid - therapeutic use | Humans | Colorectal Neoplasms - prevention & control | Colonic Polyps - epidemiology | Folic Acid - administration & dosage | Adenomatous Polyps - epidemiology | Adenomatous Polyps - prevention & control | Dose-Response Relationship, Drug | Adenocarcinoma - prevention & control | Intestinal Polyps - prevention & control | Treatment Failure | Colonic Polyps - prevention & control | Research Design | Relapse | Oncology, Experimental | Analysis | Clinical trials | Research | Cancer | Diseases
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14. Full Text Serum 25-hydroxyVitamin D and the risk of cardiovascular disease: Dose-response meta-analysis of prospective studies1-3
by Zhang, Runhua and Li, Bohong and Gao, Xiang and Tian, Rui and Pan, Yuesong and Jiang, Yong and Gu, Hongqiu and Wang, Yilong and Wang, Yongjun and Liu, Gaifen
American Journal of Clinical Nutrition, ISSN 0002-9165, 04/2017, Volume 105, Issue 4, pp. 810 - 819
Cardiovascular disease | Dose-response | 25-hydroxyVitamin D | CVD mortality | Metaanalysis
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15. Full Text Amitriptyline to relieve pain in juvenile idiopathic arthritis: a pilot study using Bayesian metaanalysis of multiple N-of-1 clinical trials
by Adam M Huber and George A Tomlinson and Gideon Koren and Brian M Feldman
The Journal of Rheumatology, ISSN 0315-162X, 05/2007, Volume 34, Issue 5, pp. 1125 - 1132
OBJECTIVE: Using serial N-of-1 trials and subsequent analysis with Bayesian methods may allow study of therapies using small numbers of subjects. Our research... 
Pain | Bayesian statistics | Juvenile idiopathic arthritis | Metaanalysis | RHEUMATOID-ARTHRITIS | pain | metaanalysis | INTENSITY | SYMPTOMS | RHEUMATOLOGY | juvenile idiopathic arthritis | FLUOXETINE | SINGLE-SUBJECT DATA | STATISTICAL-ANALYSIS | CHILDREN | ANTIDEPRESSANTS | FIBROMYALGIA | DOUBLE-BLIND | Meta-Analysis as Topic | Double-Blind Method | Humans | Male | Treatment Outcome | Analgesics, Non-Narcotic - therapeutic use | Arthritis, Juvenile - drug therapy | Arthritis, Juvenile - physiopathology | Dose-Response Relationship, Drug | Pilot Projects | Sample Size | Pain - drug therapy | Pain - physiopathology | Adolescent | Arthritis, Juvenile - complications | Bayes Theorem | Pain - etiology | Female | Amitriptyline - therapeutic use | Pain Measurement | Child
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16. Full Text Generating the evidence for risk reduction: A contribution to the future of food-based dietary guidelines
by Schwingshackl, Lukas and Schlesinger, Sabrina and Devleesschauwer, Brecht and Hoffmann, Georg and Bechthold, Angela and Schwedhelm, Carolina and Iqbal, Khalid and Knüppel, Sven and Boeing, Heiner
Proceedings of the Nutrition Society, ISSN 0029-6651, 11/2018, Volume 77, Issue 4, pp. 432 - 444
A major advantage of analyses on the food group level is that the results are better interpretable compared with nutrients or complex dietary patterns. Such... 
Evidence | Food-based dietary guidelines | Meta-analysis | SYSTEMATIC REVIEWS | GLYCEMIC CONTROL | APPARENTLY HEALTHY-ADULTS | MEDITERRANEAN DIET | MULTIVARIATE METAANALYSIS | NETWORK METAANALYSIS | DOSE-RESPONSE METAANALYSIS | NUTRITION & DIETETICS | CARDIOVASCULAR-DISEASE | WHOLE-GRAIN | PRIMARY PREVENTION | Quality-Adjusted Life Years | Meta-Analysis as Topic | Primary Prevention | Health Promotion | Diet | Humans | Food - classification | Feeding Behavior | Nutrition Policy | Research Design | Intervention | Bias | Clinical trials | Risk | Cardiovascular disease | Systematic review | Guidelines | Meat | Literature reviews | Atherosclerosis | Nutrients | Nonlinear response | Public health | Food | Hypertension | Risk reduction | Data processing | Studies | Nutrition research | Reviews | Lifestyles | Diabetes | Health risk assessment | Cancer
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17. Full Text Association between clinically recorded alcohol consumption and initial presentation of 12 cardiovascular diseases: population based cohort study using linked health records
by Bell, Steven and Daskalopoulou, Marina and Rapsomaniki, Eleni and George, Julie and Britton, Annie and Bobak, Martin and Casas, Juan P and Dale, Caroline E and Denaxas, Spiros and Shah, Anoop D and Hemingway, Harry
BMJ, ISSN 0959-8138, 3/2017, Volume 356, p. j909
Objectives To investigate the association between alcohol consumption and cardiovascular disease at higher resolution by examining the initial lifetime... 
DOSE-RESPONSE METAANALYSIS | MEDICINE, GENERAL & INTERNAL | PRIMARY-CARE | RISK-FACTORS | DRINKING PATTERNS | ANGINA-PECTORIS | ACUTE MYOCARDIAL-INFARCTION | SUDDEN CARDIAC DEATH | ISCHEMIC-HEART-DISEASE | PHYSICAL-ACTIVITY | MENDELIAN RANDOMIZATION | Multivariate Analysis | Follow-Up Studies | Humans | Middle Aged | Proportional Hazards Models | Male | Alcohol Drinking - epidemiology | England - epidemiology | Sex Factors | Cardiovascular Diseases - epidemiology | Female | Primary Health Care | Electronic Health Records | Cohort Studies
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