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NATURE REVIEWS MOLECULAR CELL BIOLOGY, ISSN 1471-0072, 06/2016, Volume 17, Issue 6, pp. 337 - 349
The Fanconi anaemia pathway repairs DNA interstrand crosslinks (ICLs) in the genome. Our understanding of this complex pathway is still evolving, as new... 
COMPLEMENTATION GROUP-M | DNA-POLYMERASE-ZETA | FANCD2 MONOUBIQUITINATION | XERODERMA-PIGMENTOSUM | CROSS-LINK REPAIR | REPLICATION FORK RECOVERY | HOMOLOGOUS-RECOMBINATION | GENOME STABILITY | DOUBLE-STRAND BREAK | BONE-MARROW FAILURE | CELL BIOLOGY
Journal Article
09/2013
Systematic reverse-engineering of functional genome architecture requires precise modifications of gene sequences and transcription levels. The development and... 
TALEs | Transcriptional modulation | Homologous recombination | Non-homologous end joining | Genome editing | Double-strand break
Web Resource
Nucleic Acids Research, ISSN 0305-1048, 04/2013, Volume 41, Issue 7, pp. 4336 - 4343
Journal Article
Molecular Cell, ISSN 1097-2765, 10/2019, Volume 76, Issue 2, pp. 346 - 358
DNA double-strand breaks (DSBs) pose a constant threat to genomic integrity. Such DSBs need to be repaired to preserve homeostasis at both the cellular and... 
senescence | proliferation | cell cycle | DNA damage | cell cycle checkpoint | double-strand break | DNA repair | cytotoxicity | p53
Journal Article
Nature, ISSN 0028-0836, 08/2017, Volume 548, Issue 7668, pp. 413 - 419
Journal Article
BMB Reports, ISSN 1976-6696, 2019, Volume 52, Issue 8, pp. 475 - 481
The evolution of genome editing technology based on CRISPR (clustered regularly interspaced short palindromic repeats) system has led to a paradigm shift in... 
CRISPR | Genome editing | NHEJ | DNA double-strand break | HDR
Journal Article
EMBO Journal, ISSN 0261-4189, 12/2014, Volume 33, Issue 23, pp. 2860 - 2879
Journal Article
NATURE REVIEWS MOLECULAR CELL BIOLOGY, ISSN 1471-0072, 06/2014, Volume 15, Issue 6, pp. 369 - 383
Homologous recombination is crucial for genome stability and for genetic exchange. Although our knowledge of the principle steps in recombination and its... 
SISTER-CHROMATID COHESION | RAD51 RECOMBINASE | NUCLEAR ARCHITECTURE | ESCHERICHIA-COLI | SACCHAROMYCES-CEREVISIAE | RECA PROTEIN | MITOTIC RECOMBINATION | DOUBLE-STRAND-BREAK | REAL-TIME | MEIOTIC RECOMBINATION | CELL BIOLOGY
Journal Article