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Journal Article
2018, First edition., Human diseases and conditions collection, ISBN 1944749616, xiii, 72 pages
This book presents Down syndrome, which is the most common chromosomal disorder in humans, occurring at a rate of about 1 in 700 births. It describes the... 
Down syndrome
Book
Journal Article
Journal of Alzheimer's disease, ISSN 1387-2877, 2017, Volume 56, Issue 2, pp. 459 - 470
Overexpression of the amyloid precursor protein (APP) gene on chromosome 21 in Down syndrome (DS) has been linked to increased brain amyloid levels and... 
APP | amyloid β-protein precursor | trisomy 21 | amyloid-β | dementia | down syndrome | partial trisomy 21 | PiB-PET | Alzheimer's disease | YOUNG-ADULTS | LOCUS DUPLICATION | NEUROSCIENCES | APOLIPOPROTEIN-E | amyloid-beta | INTELLECTUAL DISABILITY | POSITRON-EMISSION-TOMOGRAPHY | HIGH-RESOLUTION | PSYCHIATRIC-DISORDERS | PATIENT | amyloid beta-protein precursor | PLASMA AMYLOID-BETA | Down Syndrome - pathology | Brain - diagnostic imaging | Down Syndrome - metabolism | Humans | Male | Alzheimer Disease - pathology | Brain - metabolism | Phenotype | Down Syndrome - diagnostic imaging | Alzheimer Disease - metabolism | Amyloid beta-Protein Precursor - metabolism | Down Syndrome - genetics | Brain - pathology | Aged | Alzheimer Disease - diagnostic imaging | Alzheimer Disease - genetics | Neuroimaging | Brain | Trisomy | Neuropathology | Pathogenesis | Psychology | Down's syndrome | Autopsy | Neurodegeneration | Older people | Tomography | Dementia disorders | Aging | Degeneration | Age | Phenotypes | Autopsies | Neurodegenerative diseases | Positron emission | Down syndrome | Measuring techniques | Amyloid precursor protein | Chromosome 21 | Multidisciplinary research | Adults | Positron emission tomography | Geriatrics | Dementia | Trisomy 21 | Alzheimer’s disease | Partial Trisomy 21 | Amyloid beta-Protein Precursor
Journal Article
Alzheimer's & dementia, ISSN 1552-5260, 2015, Volume 11, Issue 6, pp. 700 - 709
Journal Article
2015, Clinics in developmental medicine (unnumbered), ISBN 9781909962477, xvii, 296
Book
Neurobiology of disease, ISSN 0969-9961, 2014, Volume 69, pp. 65 - 75
Journal Article
Journal Article
2016, Proza o li͡ubvi i boli, ISBN 5699912339, 315 pages
Book
Alzheimer's & dementia, ISSN 1552-5260, 07/2017, Volume 13, Issue 7, pp. P1496 - P1497
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 2014, Volume 74, pp. 204 - 218
Abstract Individuals with Down syndrome (DS), a genetic condition caused by triplication of chromosome 21, are characterized by intellectual disability and are... 
Neurology | Pharmacotherapy | Down syndrome | Alzheimer's disease | 5-HT1A receptor | Cognitive impairment | 5-HT1A RECEPTORS | ALZHEIMERS-DISEASE | BRAIN-DEVELOPMENT | EARLY PHARMACOTHERAPY | AMYLOID PRECURSOR PROTEIN | SYNAPTIC PLASTICITY | NEUROSCIENCES | DOWN-SYNDROME MICE | SYNDROME MOUSE MODEL | GRANULE CELL PRECURSORS | DENTATE GYRUS | Dendrites - pathology | Endosomes - physiology | Methyl-CpG-Binding Protein 2 - metabolism | Male | Down Syndrome - physiopathology | Hippocampus - drug effects | Alzheimer Disease - pathology | Neuroprotective Agents - pharmacology | Alzheimer Disease - prevention & control | Dendrites - physiology | Endosomes - drug effects | Cognition - physiology | Female | Neurogenesis - drug effects | Receptor, Serotonin, 5-HT1A - metabolism | Disease Models, Animal | Animals, Newborn | Dendrites - drug effects | Down Syndrome - pathology | Fluoxetine - pharmacology | Alzheimer Disease - physiopathology | Mice, Inbred C57BL | Neural Stem Cells - drug effects | Neural Stem Cells - physiology | Mice, Transgenic | Hippocampus - pathology | Endosomes - pathology | Cognition - drug effects | Neural Stem Cells - pathology | Mice, Inbred C3H | Animals | Neurogenesis - physiology | Down Syndrome - drug therapy | Hippocampus - physiopathology | Down Syndrome - psychology | Nootropic Agents - pharmacology | Infants (Newborn) | Fluoxetine | Analysis | Amyloid beta-protein | Protein binding
Journal Article