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Development of new incretin drugs: promising therapies, 12/2006
New agents are being added to the armamentarium of drugs used for the treatment of diabetes mellitus. Today, extensive research is being conducted on incretin... 
Diabetes mellitus, GLP-1, GIP, DPP-IV
Journal
European Journal of Medicinal Chemistry, ISSN 0223-5234, 10/2019, Volume 180, pp. 99 - 110
Biologically active or bioactive peptides are unique amino acid sequences found encrypted in food proteins. These peptides, upon hydrolysis, can exert positive... 
Bioactive peptide | ACE | DPP-IV | FGMP | Buffalo colostrum
Journal Article
Diabetes, obesity & metabolism, ISSN 1462-8902, 11/2014, Volume 16, Issue 11, pp. 1078 - 1086
  Aims To investigate individual patient data from a comprehensive trials programme to evaluate the safety and efficacy of the dipeptidyl peptidase-4 (DPP-4)... 
Diabetes mellitus | DPP-IV inhibitor | Drug therapy | Medical research | Diabetes
Journal Article
International Dairy Journal, ISSN 0958-6946, 09/2015, Volume 48, pp. 66 - 72
Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are gut-derived peptides and potentiate insulin secretion after meal.... 
IV INHIBITORY PEPTIDES | DPP-IV | HORMONE | HEALTHY-SUBJECTS | FOOD SCIENCE & TECHNOLOGY | WHEY-PROTEIN | BLOOD-GLUCOSE | CATTLE | DIPEPTIDYL | MILK | FOOD
Journal Article
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 02/2018, Volume 20, pp. 47 - 58
The incretin therapies glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) and dipeptidyl peptidase‐IV (DPP‐IV) inhibitors are now well‐established as second... 
clinical trial | antidiabetic drug | cohort study | GLP‐1 analogue | DPP‐IV inhibitor | incretin therapy | GLP-1 analogue | DPP-IV inhibitor
Journal Article
Food Research International, ISSN 0963-9969, 07/2019, Volume 121, pp. 577 - 585
Legumes, such as chickpea, represent a good source of high quality proteins for which there is an increasing global consumer demand. A chickpea protein... 
Chickpea | Microscopy, ACE, DPP-IV | Emulsion | Enzyme inhibitory | Antioxidant activity | Antioxidants | Precipitation (Meteorology) | Analysis | Angiotensin | Angiotensin converting enzyme
Journal Article
International Dairy Journal, ISSN 0958-6946, 02/2016, Volume 53, pp. 37 - 44
The different potential for release of dipeptidyl peptidase IV (DPP-IV)-inhibitory peptides from bovine and caprine milk casein was assessed by in silico... 
DIETARY PROTEINS | HYDROLYSIS | DPP-IV | IDENTIFICATION | FOOD SCIENCE & TECHNOLOGY | Hydrolysis | Peptides | Casein | Comparative analysis | Proteases | Milk
Journal Article
Journal Article
Journal of Applied Pharmaceutical Science, 01/2019, Volume 9, Issue 1, pp. 28 - 32
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 10/2013, Volume 23, Issue 19, pp. 5361 - 5366
A series of novel tri-2,3,5-substituted tetrahydropyran analogs were synthesized and evaluated as inhibitors of dipeptidyl peptidase 4 (DPP-4) for the... 
Tetrahydropyran | DPP-IV | Diabetes | DPP-4 inhibitors | POTENT | CHEMISTRY, MEDICINAL | CLONING | CHEMISTRY, ORGANIC | HOMOLOG | IDENTIFICATION | RATIONAL DESIGN
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 09/2019, Volume 859, p. 172521
Dipeptidyl peptidase-4 (DPP-4) inhibitors prevent the degradation of glucagon-like peptide-1 (GLP-1) and improve glycemic control. The GLP-1 insulinotropic... 
Dipeptidyl peptidase-4 inhibitor | Glucagon-like peptide-1 | Hepatic portal | Intestine | Dipeptidyl peptidase-4 | LOCALIZATION | METFORMIN | PHYSIOLOGY | DPP-IV | GLP-1 | INSULIN-SECRETION | TISSUE | MECHANISMS | ANAGLIPTIN | PHARMACOLOGY & PHARMACY
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2018, Volume 115, Issue 7, pp. E1437 - E1445
Dipeptidyl peptidases 8 and 9 are intracellular N-terminal dipeptidyl peptidases (preferentially postproline) associated with pathophysiological roles in... 
DPP4 | DPP8 | SUMO1 | DPP9 | LOCALIZATION | COMPLEX | DPP-IV | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | LOOP | SUBSTRATE-SPECIFICITY | INHIBITION | ENZYMATIC-ACTIVITY | EXPRESSION | REVEALS | Biological Sciences | PNAS Plus
Journal Article
Food Research International, ISSN 0963-9969, 07/2019, Volume 121, pp. 524 - 532
Brewer's spent grain (BSG) is a co-product of the brewing industry that has been shown to contain a range of bioactive peptides encrypted within its protein... 
Alkaline extraction | DPP-IV | Peptides | BSG | Bioactivity | Antioxidant | Protein | IL-6 | Antioxidants | Interleukins | Protein hydrolysates | Brewing industry | Calpain | Interferon | Aspartic proteinases | Breweries | Mitogens | Mass spectrometry | High performance liquid chromatography
Journal Article
Food Research International, ISSN 0963-9969, 07/2015, Volume 73, pp. 149 - 161
The dairy industry generates increased amounts of whey from both cheese and casein production facilities. Whey presents an elevated content of lactose and... 
Protein hydrolysis | By-product | Whey | Bioactive peptides | FOOD SCIENCE & TECHNOLOGY | PROTEIN-DERIVED DIPEPTIDES | ENZYME INHIBITORY-ACTIVITIES | BETA-LACTOGLOBULIN | SIMULATED GASTROINTESTINAL DIGESTION | IV DPP-IV | MILK-PROTEINS | IN-VITRO | ALPHA-LACTALBUMIN | CHEESE WHEY | Casein | Biochemical oxygen demand | Biological products
Journal Article