Neurobiology of Disease, ISSN 0969-9961, 2010, Volume 41, Issue 3, pp. 661 - 668
Abstract Cisplatin is a platinum-based chemotherapeutic agent that induces peripheral neuropathy in 30% of patients. Peripheral neuropathy is the dose limiting...
Neurology | DRG neurons | Chemotherapy: Neuropathy | Cisplatin | Mitochondria: DNA and DNA damage | INDUCED APOPTOSIS | TRANSCRIPTION | RECEPTOR | OXALIPLATIN | MAMMALIAN-CELLS | NEUROTOXICITY | NEUROSCIENCES | CHEMOTHERAPY | IN-VITRO | NEUROPATHY | REPLICATION | DNA Damage - drug effects | Neurons - pathology | DNA, Mitochondrial - metabolism | Mice, Inbred C57BL | Cells, Cultured | Rats | Male | Rats, Sprague-Dawley | Cisplatin - metabolism | Animals | Cisplatin - toxicity | DNA Damage - physiology | Ganglia, Spinal - pathology | Mice | Neurons - metabolism | Ganglia, Spinal - drug effects | Neurons - drug effects | Ganglia, Spinal - metabolism | Chemotherapy | Neurons | Mitochondrial DNA | Tumor proteins | Ganglion | Cancer | Index Medicus | DRG Neurons
Neurology | DRG neurons | Chemotherapy: Neuropathy | Cisplatin | Mitochondria: DNA and DNA damage | INDUCED APOPTOSIS | TRANSCRIPTION | RECEPTOR | OXALIPLATIN | MAMMALIAN-CELLS | NEUROTOXICITY | NEUROSCIENCES | CHEMOTHERAPY | IN-VITRO | NEUROPATHY | REPLICATION | DNA Damage - drug effects | Neurons - pathology | DNA, Mitochondrial - metabolism | Mice, Inbred C57BL | Cells, Cultured | Rats | Male | Rats, Sprague-Dawley | Cisplatin - metabolism | Animals | Cisplatin - toxicity | DNA Damage - physiology | Ganglia, Spinal - pathology | Mice | Neurons - metabolism | Ganglia, Spinal - drug effects | Neurons - drug effects | Ganglia, Spinal - metabolism | Chemotherapy | Neurons | Mitochondrial DNA | Tumor proteins | Ganglion | Cancer | Index Medicus | DRG Neurons
Journal Article
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, ISSN 1940-087X, 09/2019, Issue 151
There are growing interests to study the molecular and cellular interactions among immune cells and sensory neurons in the dorsal root ganglia after peripheral...
CX3CR1 | CSF1R | CELLS | ACTIVATION | MULTIDISCIPLINARY SCIENCES | FACS | MAFIA | NEUROPATHIC PAIN | Neuroscience | sensory neuron | MICROGLIA | nerve injury | DRG | Issue 151 | CONTRIBUTES | Macrophage
CX3CR1 | CSF1R | CELLS | ACTIVATION | MULTIDISCIPLINARY SCIENCES | FACS | MAFIA | NEUROPATHIC PAIN | Neuroscience | sensory neuron | MICROGLIA | nerve injury | DRG | Issue 151 | CONTRIBUTES | Macrophage
Journal Article
Pain, ISSN 0304-3959, 06/2013, Volume 154, Issue 6, pp. 882 - 889
The paclitaxel treatment increases TRPV1 expression in DRG neurons and may contribute to functional peripheral neuropathic pain. Peripheral neuropathy is a...
Transient receptor potential vanilloid 1 | Dorsal root ganglion | TRPV1 antagonist capsazepine | Paclitaxel | Peripheral neuropathic pain | HEAT HYPERALGESIA | DRG NEURONS | INCREASES | PAINFUL PERIPHERAL NEUROPATHY | TRPV1 | NEUROSCIENCES | SENSORY NEURONS | CLINICAL NEUROLOGY | CAPSAICIN RECEPTOR | INDUCED HYPERALGESIA | CHANNEL | ANESTHESIOLOGY | EXPRESSION | Hyperalgesia - chemically induced | Pain Threshold - physiology | Paclitaxel - pharmacology | Hyperalgesia - metabolism | Rats, Wistar | Rats | Male | Ganglia, Spinal - physiopathology | TRPV Cation Channels - genetics | Hyperalgesia - physiopathology | TRPV Cation Channels - metabolism | Animals | Ruthenium Red - pharmacology | Pain Threshold - drug effects | Neurons - metabolism | Ganglia, Spinal - drug effects | Neurons - drug effects | Ganglia, Spinal - metabolism | Ganglion
Transient receptor potential vanilloid 1 | Dorsal root ganglion | TRPV1 antagonist capsazepine | Paclitaxel | Peripheral neuropathic pain | HEAT HYPERALGESIA | DRG NEURONS | INCREASES | PAINFUL PERIPHERAL NEUROPATHY | TRPV1 | NEUROSCIENCES | SENSORY NEURONS | CLINICAL NEUROLOGY | CAPSAICIN RECEPTOR | INDUCED HYPERALGESIA | CHANNEL | ANESTHESIOLOGY | EXPRESSION | Hyperalgesia - chemically induced | Pain Threshold - physiology | Paclitaxel - pharmacology | Hyperalgesia - metabolism | Rats, Wistar | Rats | Male | Ganglia, Spinal - physiopathology | TRPV Cation Channels - genetics | Hyperalgesia - physiopathology | TRPV Cation Channels - metabolism | Animals | Ruthenium Red - pharmacology | Pain Threshold - drug effects | Neurons - metabolism | Ganglia, Spinal - drug effects | Neurons - drug effects | Ganglia, Spinal - metabolism | Ganglion
Journal Article
Pain Medicine, ISSN 1526-2375, 06/2019, Volume 20, Issue Supplement_1, pp. S41 - S46
Abstract Objective The objective of this study is to review the available evidence for dorsal root ganglion (DRG) stimulation for the treatment of complex...
Spinal Cord Stimulation | Postsurgical Chronic Pain | Complex Regional Pain Syndrome | DRG Stimulation | INTERVENTIONAL THERAPIES | CHRONIC PELVIC PAIN | RISK-FACTORS | CHRONIC GROIN | SINGLE-CENTER | INGUINAL-HERNIA | MEDICINE, GENERAL & INTERNAL | SPINAL-CORD STIMULATION | CHRONIC NEUROPATHIC PAIN | DRG | ANESTHESIOLOGY | TOTAL KNEE | Knee | Hernia | Ostomy | Pain | Dorsal root ganglia | Surgery | Pain management | Neuropathy | Dorsal roots | Neuromodulation | Feet | Review
Spinal Cord Stimulation | Postsurgical Chronic Pain | Complex Regional Pain Syndrome | DRG Stimulation | INTERVENTIONAL THERAPIES | CHRONIC PELVIC PAIN | RISK-FACTORS | CHRONIC GROIN | SINGLE-CENTER | INGUINAL-HERNIA | MEDICINE, GENERAL & INTERNAL | SPINAL-CORD STIMULATION | CHRONIC NEUROPATHIC PAIN | DRG | ANESTHESIOLOGY | TOTAL KNEE | Knee | Hernia | Ostomy | Pain | Dorsal root ganglia | Surgery | Pain management | Neuropathy | Dorsal roots | Neuromodulation | Feet | Review
Journal Article
Brain, ISSN 0006-8950, 05/2019, Volume 142, Issue 5, pp. 1215 - 1226
Using electrophysiology, North et al. show that ectopic signalling in dorsal root ganglion neuron somata is directly associated with neuropathic pain....
TRPV1 | DRG transcriptomics | NEUROSCIENCES | SENSORY NEURONS | CLINICAL NEUROLOGY | machine learning in healthcare | RESPONSES | GENE | spontaneous activity | DRG | neuropathy | CHANNELS | EXPRESSION
TRPV1 | DRG transcriptomics | NEUROSCIENCES | SENSORY NEURONS | CLINICAL NEUROLOGY | machine learning in healthcare | RESPONSES | GENE | spontaneous activity | DRG | neuropathy | CHANNELS | EXPRESSION
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, p. e0168228
Neurological disorders in ruminants have an important impact on veterinary health, but very few host-specific in vitro models have been established to study...
SPINAL GANGLIA | IN-VITRO | GENE-RELATED PEPTIDE | PRIMARY AFFERENT NEURONS | MULTIDISCIPLINARY SCIENCES | E-CADHERIN EXPRESSION | IMMUNOHISTOCHEMICAL CHARACTERIZATION | PRIMARY SENSORY NEURONS | SCHWANN-CELLS | SATELLITE GLIAL-CELLS | NERVE GROWTH-FACTOR | Microscopy, Electron, Transmission | Animals | Cattle | Coculture Techniques | Cells, Cultured | Ganglia, Spinal - pathology | Cell culture | Nervous system diseases | Dorsal root ganglia | Innovations | Models | Diseases | Spinal cord | Cell survival | Neurons | Axonogenesis | Dietary supplements | Calves | Cultures | Nervous system | Kinases | Veterinary medicine | Ganglia | Neurological diseases | Studies | Pain | Rodents | Supplementation | Food consumption | Immunofluorescence | Growth factors | Viability
SPINAL GANGLIA | IN-VITRO | GENE-RELATED PEPTIDE | PRIMARY AFFERENT NEURONS | MULTIDISCIPLINARY SCIENCES | E-CADHERIN EXPRESSION | IMMUNOHISTOCHEMICAL CHARACTERIZATION | PRIMARY SENSORY NEURONS | SCHWANN-CELLS | SATELLITE GLIAL-CELLS | NERVE GROWTH-FACTOR | Microscopy, Electron, Transmission | Animals | Cattle | Coculture Techniques | Cells, Cultured | Ganglia, Spinal - pathology | Cell culture | Nervous system diseases | Dorsal root ganglia | Innovations | Models | Diseases | Spinal cord | Cell survival | Neurons | Axonogenesis | Dietary supplements | Calves | Cultures | Nervous system | Kinases | Veterinary medicine | Ganglia | Neurological diseases | Studies | Pain | Rodents | Supplementation | Food consumption | Immunofluorescence | Growth factors | Viability
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 02/2017, Volume 37, Issue 6, pp. 1648 - 1661
Collateral branches from axons are key components of functional neural circuits that allow neurons to connect with multiple synaptic targets. Like axon growth...
DRG | MAP7 | Axon | Sensory neuron | Microtubule | Collateral branch | collateral branch | ENSCONSIN | REGENERATION | SCHIZOPHRENIA | MICROTUBULE-ASSOCIATED PROTEIN | NEUROSCIENCES | microtubule | sensory neuron | E-MAP-115 | GENE | GROWTH | PURIFICATION | axon | EXPRESSION | BRAIN | Pregnancy | Animals | Cells, Cultured | Rats | Female | Axons - physiology | Mice | Neurons - metabolism | Microtubule-Associated Proteins - biosynthesis | Rats, Sprague-Dawley | Ganglia, Spinal - metabolism
DRG | MAP7 | Axon | Sensory neuron | Microtubule | Collateral branch | collateral branch | ENSCONSIN | REGENERATION | SCHIZOPHRENIA | MICROTUBULE-ASSOCIATED PROTEIN | NEUROSCIENCES | microtubule | sensory neuron | E-MAP-115 | GENE | GROWTH | PURIFICATION | axon | EXPRESSION | BRAIN | Pregnancy | Animals | Cells, Cultured | Rats | Female | Axons - physiology | Mice | Neurons - metabolism | Microtubule-Associated Proteins - biosynthesis | Rats, Sprague-Dawley | Ganglia, Spinal - metabolism
Journal Article
Neuroscience, ISSN 0306-4522, 2016, Volume 331, pp. 148 - 157
Graphical abstract
Neurology | DRG | pain | S1R | Sigma-1 receptor | dorsal root ganglion | LOCALIZATION | CELLS | PHOSPHORYLATION | ER STRESS | NEUROSCIENCES | CHAPERONES | GENE | SITES | MICE | MODULATOR | Immunohistochemistry | Mice, Inbred C57BL | Antibodies | Endoplasmic Reticulum - metabolism | Male | Mice, Transgenic | Phosphopyruvate Hydratase - metabolism | Ganglia, Spinal - ultrastructure | Receptors, sigma - genetics | Mice, 129 Strain | RNA, Messenger - metabolism | Rats, Sprague-Dawley | Blotting, Western | Microscopy, Immunoelectron | Microscopy, Confocal | Nuclear Envelope - metabolism | Receptors, sigma - immunology | Animals | Neurons - ultrastructure | Cell Membrane - metabolism | Neurons - metabolism | Receptors, sigma - metabolism | Real-Time Polymerase Chain Reaction | Ganglia, Spinal - metabolism | Viral antibodies
Neurology | DRG | pain | S1R | Sigma-1 receptor | dorsal root ganglion | LOCALIZATION | CELLS | PHOSPHORYLATION | ER STRESS | NEUROSCIENCES | CHAPERONES | GENE | SITES | MICE | MODULATOR | Immunohistochemistry | Mice, Inbred C57BL | Antibodies | Endoplasmic Reticulum - metabolism | Male | Mice, Transgenic | Phosphopyruvate Hydratase - metabolism | Ganglia, Spinal - ultrastructure | Receptors, sigma - genetics | Mice, 129 Strain | RNA, Messenger - metabolism | Rats, Sprague-Dawley | Blotting, Western | Microscopy, Immunoelectron | Microscopy, Confocal | Nuclear Envelope - metabolism | Receptors, sigma - immunology | Animals | Neurons - ultrastructure | Cell Membrane - metabolism | Neurons - metabolism | Receptors, sigma - metabolism | Real-Time Polymerase Chain Reaction | Ganglia, Spinal - metabolism | Viral antibodies
Journal Article
Toxicology Letters, ISSN 0378-4274, 01/2020, Volume 318, pp. 104 - 113
Bupivacaine (BP) is commonly used as a local anaesthetic(LA) in the clinic, but it can also cause neurotoxicity, especially in patients with diabetes. Previous...
Ku70 | DRG | Neurotoxicity | Bupivacaine | DNA repair | DNA damage | APOPTOSIS | OXIDATIVE STRESS | DNA-DAMAGE REPAIR | DIABETIC-NEUROPATHY | NUCLEAR LOSS | ANESTHESIA | LIDOCAINE | IN-VIVO | TOXICOLOGY | INTRATHECAL BUPIVACAINE | BLOCK DURATION
Ku70 | DRG | Neurotoxicity | Bupivacaine | DNA repair | DNA damage | APOPTOSIS | OXIDATIVE STRESS | DNA-DAMAGE REPAIR | DIABETIC-NEUROPATHY | NUCLEAR LOSS | ANESTHESIA | LIDOCAINE | IN-VIVO | TOXICOLOGY | INTRATHECAL BUPIVACAINE | BLOCK DURATION
Journal Article
Brain Research, ISSN 0006-8993, 08/2018, Volume 1692, pp. 1 - 8
Melatonin, a powerful antioxidant, participates in the regulation of important physiological and pathological processes. We investigated the actions of...
DRG | Excitability | Action potential | Melatonin | MT1 | Dorsal root ganglion | OXIDATIVE STRESS | LIGHT | SPINAL-CORD | CURRENTS | NEUROSCIENCES | NEUROPATHIC PAIN | INHIBITION | RECEPTORS | SYNTHESIS IMPAIRMENT | MODULATION | BRAIN | Membrane Potentials - drug effects | Receptor, Melatonin, MT2 - genetics | Electric Stimulation | Gene Expression - drug effects | Rats, Wistar | Ribosomal Proteins - genetics | Rats | Male | Ganglia, Spinal - cytology | Antioxidants - pharmacology | RNA, Messenger - metabolism | Receptor, Melatonin, MT1 - genetics | Ribosomal Proteins - metabolism | Neurons - classification | Patch-Clamp Techniques | Animals | Neurons - drug effects | Receptor, Melatonin, MT2 - metabolism | Melatonin - pharmacology | Receptor, Melatonin, MT1 - metabolism | Ganglion | Neurons | Analysis
DRG | Excitability | Action potential | Melatonin | MT1 | Dorsal root ganglion | OXIDATIVE STRESS | LIGHT | SPINAL-CORD | CURRENTS | NEUROSCIENCES | NEUROPATHIC PAIN | INHIBITION | RECEPTORS | SYNTHESIS IMPAIRMENT | MODULATION | BRAIN | Membrane Potentials - drug effects | Receptor, Melatonin, MT2 - genetics | Electric Stimulation | Gene Expression - drug effects | Rats, Wistar | Ribosomal Proteins - genetics | Rats | Male | Ganglia, Spinal - cytology | Antioxidants - pharmacology | RNA, Messenger - metabolism | Receptor, Melatonin, MT1 - genetics | Ribosomal Proteins - metabolism | Neurons - classification | Patch-Clamp Techniques | Animals | Neurons - drug effects | Receptor, Melatonin, MT2 - metabolism | Melatonin - pharmacology | Receptor, Melatonin, MT1 - metabolism | Ganglion | Neurons | Analysis
Journal Article
ACS Applied Materials & Interfaces, ISSN 1944-8244, 09/2017, Volume 9, Issue 36, pp. 30318 - 30328
Understanding and controlling the interactions occurring between cells and engineered materials are central challenges toward progress in the development of...
Research | functional soft materials | biologically compliant materials | gels | 3D cell culture | 4D printing | programmable cell-scaffold interactions | dorsal root ganglion (DRG) | NEURONAL NETWORKS | INTRACELLULAR-TRANSPORT | MATERIALS SCIENCE, MULTIDISCIPLINARY | TISSUE | NANOSCIENCE & NANOTECHNOLOGY | RELATION PHASE SPECTROSCOPY | PERIPHERAL-NERVE | ADHESION | NEURITE OUTGROWTH | SURFACE | SOFT LITHOGRAPHY | LIGHT INTERFERENCE MICROSCOPY | Tissue Scaffolds | Animals | Cell Proliferation | Hydrogels | Mice | Polyhydroxyethyl Methacrylate - chemistry | Ganglia, Spinal | Tissue Engineering | Functional soft materials | Gels | Programmable cell-scaffold interactions | Dorsal root ganglion (DRG) | 4D Printing | Biologically compliant materials | Naturvetenskap | Natural Sciences | Kemi | Chemical Sciences
Research | functional soft materials | biologically compliant materials | gels | 3D cell culture | 4D printing | programmable cell-scaffold interactions | dorsal root ganglion (DRG) | NEURONAL NETWORKS | INTRACELLULAR-TRANSPORT | MATERIALS SCIENCE, MULTIDISCIPLINARY | TISSUE | NANOSCIENCE & NANOTECHNOLOGY | RELATION PHASE SPECTROSCOPY | PERIPHERAL-NERVE | ADHESION | NEURITE OUTGROWTH | SURFACE | SOFT LITHOGRAPHY | LIGHT INTERFERENCE MICROSCOPY | Tissue Scaffolds | Animals | Cell Proliferation | Hydrogels | Mice | Polyhydroxyethyl Methacrylate - chemistry | Ganglia, Spinal | Tissue Engineering | Functional soft materials | Gels | Programmable cell-scaffold interactions | Dorsal root ganglion (DRG) | 4D Printing | Biologically compliant materials | Naturvetenskap | Natural Sciences | Kemi | Chemical Sciences
Journal Article
Pain Medicine, ISSN 1526-2375, 10/2013, Volume 14, Issue 10, pp. 1477 - 1496
Objective The purpose of the study was to systematically review the historical therapeutics for chronic pain care directed at the dorsal root ganglion (DRG)...
DRG | Spinal Cord Stimulation | Dorsal Root Ganglion | Chronic Pain | THORACIC SEGMENTAL PAIN | LUMBAR RADICULAR PAIN | LESION ADJACENT | PERCUTANEOUS PULSED RADIOFREQUENCY | SPINAL PAIN | NEUROPATHIC PAIN | CLINICAL AUDIT | MEDICINE, GENERAL & INTERNAL | DOUBLE-BLIND | NEURONS | ANESTHESIOLOGY | GENE-TRANSFER | Chronic Pain - therapy | Ganglionectomy - methods | Ganglionectomy - trends | Pulsed Radiofrequency Treatment - trends | Electric Stimulation Therapy - methods | Ganglia, Spinal - radiation effects | Humans | Pulsed Radiofrequency Treatment - methods | Ganglia, Spinal - surgery | Care and treatment | Pain | Ganglion | Health aspects | Chronic pain | Medical research | Pain management
DRG | Spinal Cord Stimulation | Dorsal Root Ganglion | Chronic Pain | THORACIC SEGMENTAL PAIN | LUMBAR RADICULAR PAIN | LESION ADJACENT | PERCUTANEOUS PULSED RADIOFREQUENCY | SPINAL PAIN | NEUROPATHIC PAIN | CLINICAL AUDIT | MEDICINE, GENERAL & INTERNAL | DOUBLE-BLIND | NEURONS | ANESTHESIOLOGY | GENE-TRANSFER | Chronic Pain - therapy | Ganglionectomy - methods | Ganglionectomy - trends | Pulsed Radiofrequency Treatment - trends | Electric Stimulation Therapy - methods | Ganglia, Spinal - radiation effects | Humans | Pulsed Radiofrequency Treatment - methods | Ganglia, Spinal - surgery | Care and treatment | Pain | Ganglion | Health aspects | Chronic pain | Medical research | Pain management
Journal Article
Journal of Neural Engineering, ISSN 1741-2560, 02/2015, Volume 12, Issue 1, pp. 016008 - 16022
Objective. The dorsal root ganglion is an attractive target for implanting neural electrode arrays that restore sensory function or provide therapy via...
Dexamethasone | Dorsal root ganglion | Microstimulation | Neural probes | PEDOT/CNT | Tissue/electrode interface | dexamethasone | ENGINEERING, BIOMEDICAL | CONTROLLED-RELEASE | HUMAN HAND | ADULT ZEBRAFISH | MICROELECTRODE ARRAYS | NEUROSCIENCES | neural probes | CARBON NANOTUBES | microstimulation | BRAIN-TISSUE | ELECTRICAL-STIMULATION | dorsal root ganglion | INTRACORTICAL MICROSTIMULATION | tissue/electrode interface | SPINAL-CORD-INJURY | INFLAMMATORY RESPONSE | Dexamethasone - chemistry | Coated Materials, Biocompatible - chemical synthesis | Nanocapsules - administration & dosage | Drug Implants - administration & dosage | Electric Conductivity | Equipment Design | Nanocapsules - chemistry | Sensitivity and Specificity | Anti-Inflammatory Agents - administration & dosage | Female | Microelectrodes | Ganglia, Spinal - immunology | Reproducibility of Results | Dexamethasone - administration & dosage | Bridged Bicyclo Compounds, Heterocyclic - chemistry | Rats | Materials Testing | Nanotubes, Carbon - ultrastructure | Spinal Cord Stimulation - instrumentation | Rats, Sprague-Dawley | Animals | Anti-Inflammatory Agents - chemistry | Nanotubes, Carbon - chemistry | Drug Implants - chemical synthesis | Polymers - chemistry | Ganglia, Spinal - drug effects | Equipment Failure Analysis | Electrodes | Roots | Carbon nanotubes | Stimulation | Impedance | Coatings | Matlab | PEDOT | electrode interface | DRG | CNT | tissue
Dexamethasone | Dorsal root ganglion | Microstimulation | Neural probes | PEDOT/CNT | Tissue/electrode interface | dexamethasone | ENGINEERING, BIOMEDICAL | CONTROLLED-RELEASE | HUMAN HAND | ADULT ZEBRAFISH | MICROELECTRODE ARRAYS | NEUROSCIENCES | neural probes | CARBON NANOTUBES | microstimulation | BRAIN-TISSUE | ELECTRICAL-STIMULATION | dorsal root ganglion | INTRACORTICAL MICROSTIMULATION | tissue/electrode interface | SPINAL-CORD-INJURY | INFLAMMATORY RESPONSE | Dexamethasone - chemistry | Coated Materials, Biocompatible - chemical synthesis | Nanocapsules - administration & dosage | Drug Implants - administration & dosage | Electric Conductivity | Equipment Design | Nanocapsules - chemistry | Sensitivity and Specificity | Anti-Inflammatory Agents - administration & dosage | Female | Microelectrodes | Ganglia, Spinal - immunology | Reproducibility of Results | Dexamethasone - administration & dosage | Bridged Bicyclo Compounds, Heterocyclic - chemistry | Rats | Materials Testing | Nanotubes, Carbon - ultrastructure | Spinal Cord Stimulation - instrumentation | Rats, Sprague-Dawley | Animals | Anti-Inflammatory Agents - chemistry | Nanotubes, Carbon - chemistry | Drug Implants - chemical synthesis | Polymers - chemistry | Ganglia, Spinal - drug effects | Equipment Failure Analysis | Electrodes | Roots | Carbon nanotubes | Stimulation | Impedance | Coatings | Matlab | PEDOT | electrode interface | DRG | CNT | tissue
Journal Article
JOURNAL OF NEUROSCIENCE, ISSN 0270-6474, 09/2019, Volume 39, Issue 38, pp. 7615 - 7627
Neuropathic pain is a chronic condition that occurs frequently after nerve injury and induces hypersensitivity or allodynia characterized by aberrant neuronal...
pain | NMDA RECEPTOR | CONDUCTION-VELOCITY | NR2B SUBUNIT | TACTILE ALLODYNIA | SPINAL-CORD | CELL-ADHESION | NEUROSCIENCES | FLRT3 | DRG | SUBSTANTIA-GELATINOSA | hyperalgesia | PRIMARY SENSORY NEURONS | MOLECULAR-MECHANISMS | Spinal cord | Phosphorylation | Animal models | Peripheral nerves | Antibodies | Viruses | Leucine | Neuropathy | Fibronectin | Cell adhesion & migration | Proteins | Pain | Dorsal root ganglia | Rodents | Cell adhesion | Sensory neurons | Horns | Dorsal roots | Injuries | Dorsal horn | Pain perception | Neurons | Axonogenesis | Activating transcription factor 3 | Hypersensitivity | Excitability | Mechanical properties | Axon guidance | Sciatic nerve
pain | NMDA RECEPTOR | CONDUCTION-VELOCITY | NR2B SUBUNIT | TACTILE ALLODYNIA | SPINAL-CORD | CELL-ADHESION | NEUROSCIENCES | FLRT3 | DRG | SUBSTANTIA-GELATINOSA | hyperalgesia | PRIMARY SENSORY NEURONS | MOLECULAR-MECHANISMS | Spinal cord | Phosphorylation | Animal models | Peripheral nerves | Antibodies | Viruses | Leucine | Neuropathy | Fibronectin | Cell adhesion & migration | Proteins | Pain | Dorsal root ganglia | Rodents | Cell adhesion | Sensory neurons | Horns | Dorsal roots | Injuries | Dorsal horn | Pain perception | Neurons | Axonogenesis | Activating transcription factor 3 | Hypersensitivity | Excitability | Mechanical properties | Axon guidance | Sciatic nerve
Journal Article
Pain Medicine, ISSN 1526-2375, 06/2019, Volume 20, Issue Supplement_1, pp. S23 - S30
Abstract Objective The dorsal root ganglion (DRG) is a novel target for neuromodulation, and DRG stimulation is proving to be a viable option in the treatment...
NERVE-FIBERS | GROIN PAIN | Pain Management | SENSORY NEURON | DRG NEURONS | Dorsal Root Ganglion Stimulation | SINGLE-CENTER | REGIONAL PAIN SYNDROME | Neuromodulation | FIELD STIMULATION | Spinal Cord Stimulation | MEDICINE, GENERAL & INTERNAL | SPINAL-CORD STIMULATION | CHRONIC NEUROPATHIC PAIN | Neurostimulation | Neuropathic Pain | ANESTHESIOLOGY | DRG Stimulation | APPROPRIATE USE | Chronic Pain | Spinal cord | Pain perception | Peripheral nerves | Homeostasis | Paresthesia | Neuropathy | Anatomy | Sensory transduction | Posture | Literature reviews | Dorsal root ganglia | Pain | Pain management | Sensory neurons | Dorsal roots | Review
NERVE-FIBERS | GROIN PAIN | Pain Management | SENSORY NEURON | DRG NEURONS | Dorsal Root Ganglion Stimulation | SINGLE-CENTER | REGIONAL PAIN SYNDROME | Neuromodulation | FIELD STIMULATION | Spinal Cord Stimulation | MEDICINE, GENERAL & INTERNAL | SPINAL-CORD STIMULATION | CHRONIC NEUROPATHIC PAIN | Neurostimulation | Neuropathic Pain | ANESTHESIOLOGY | DRG Stimulation | APPROPRIATE USE | Chronic Pain | Spinal cord | Pain perception | Peripheral nerves | Homeostasis | Paresthesia | Neuropathy | Anatomy | Sensory transduction | Posture | Literature reviews | Dorsal root ganglia | Pain | Pain management | Sensory neurons | Dorsal roots | Review
Journal Article