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Annual review of biophysics, ISSN 1936-122X, 6/2012, Volume 41, Issue 1, pp. 429 - 452
Journal Article
Molecular pharmaceutics, ISSN 1543-8384, 06/2018, Volume 15, Issue 6, pp. 2224 - 2233
Intracellular unbound drug concentrations are the pharmacologically relevant concentrations for targets inside cells. Intracellular drug concentrations are... 
unbound concentration | drug binding | proteomics | intracellular drug bioavailability | membrane partitioning | phospholipid | lipid | 3T3-L1 | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Index Medicus
Journal Article
Journal Article
ChemMedChem, ISSN 1860-7179, 02/2017, Volume 12, Issue 3, pp. 271 - 277
Alpha‐1‐acid glycoprotein (α1‐AGP) is an important blood plasma glycoprotein. Following an acute‐phase reaction such as stress, inflammation, burn, or... 
drug binding | luminescence | chirality | europium | CPL | Index Medicus
Journal Article
Expert opinion on drug delivery, ISSN 1744-7593, 12/2014, Volume 12, Issue 5, pp. 793 - 812
Journal Article
The FEBS journal, ISSN 1742-464X, 02/2014, Volume 281, Issue 3, pp. 673 - 682
Human P‐glycoprotein (P‐gp) controls drugs bioavailability by pumping structurally unrelated drugs out of cells. The X‐ray structure of the mouse P‐gp ortholog... 
drug efflux | drug‐binding sites | ABC transporters | cancer | P‐glycoprotein | drug resistance | P-glycoprotein | Drug efflux | Drug resistance | Drug-binding sites | Cancer | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | NIH 3T3 Cells | Membrane Transport Modulators - chemistry | Stereoisomerism | Drug Resistance, Multiple - drug effects | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Daunorubicin - pharmacology | Peptides, Cyclic - pharmacology | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Benzimidazoles - chemistry | Peptides, Cyclic - chemistry | Peptides, Cyclic - metabolism | Antineoplastic Agents - metabolism | Protein Isoforms - metabolism | Protein Isoforms - chemistry | Membrane Transport Modulators - pharmacology | ATP-Binding Cassette, Sub-Family B, Member 1 - chemistry | Antineoplastic Agents - pharmacology | Biological Transport - drug effects | Daunorubicin - metabolism | Binding, Competitive | Recombinant Proteins - metabolism | Catalytic Domain | Models, Molecular | Recombinant Proteins - chemistry | Antineoplastic Agents - chemistry | Daunorubicin - chemistry | Membrane Transport Modulators - metabolism | Animals | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Benzimidazoles - metabolism | Benzimidazoles - pharmacology | ATP Binding Cassette Transporter, Sub-Family B | Mice | Molecular Docking Simulation | Kinetics | Protein Isoforms - antagonists & inhibitors | Protein Isoforms - genetics | Drug resistance in microorganisms | Anthracyclines | Chemical properties | Enantiomers | Glycoproteins | Bioavailability | Binding sites | Index Medicus | drug efflux mechanism | multidrug efflux ABC transporters | drug-binding sites
Journal Article