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Journal Article
International Journal of Oncology, ISSN 1019-6439, 07/2016, Volume 49, Issue 1, pp. 153 - 163
The discovery of the TRAIL protein and its death receptors DR4/5 changed the horizon of cancer research because TRAIL specifically kills cancer cells. However,... 
cancer therapy | IAPs | apoptosis | TRAIL | c-FLIP | drug combination | C-FLIP | Drug combination | Cancer therapy | Apoptosis | LIGAND TRAIL | CASPASE-8 EXPRESSION | ANTITUMOR-ACTIVITY | NEUROBLASTOMA-CELLS | CANCER-THERAPY | DRUG-INDUCED APOPTOSIS | GENE | ONCOLOGY | ANTICANCER THERAPY | IN-VIVO | SENSITIZES | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Benzhydryl Compounds - administration & dosage | Apoptosis - drug effects | CASP8 and FADD-Like Apoptosis Regulating Protein - genetics | CASP8 and FADD-Like Apoptosis Regulating Protein - antagonists & inhibitors | Humans | Benzofurans - administration & dosage | CASP8 and FADD-Like Apoptosis Regulating Protein - biosynthesis | TNF-Related Apoptosis-Inducing Ligand - therapeutic use | X-Linked Inhibitor of Apoptosis Protein - genetics | Neoplasms - drug therapy | X-Linked Inhibitor of Apoptosis Protein - antagonists & inhibitors | Drug Resistance, Neoplasm - genetics | Neoplasms - genetics | Signal Transduction - drug effects | Cell Line, Tumor | Azocines - administration & dosage | Gene Expression Regulation, Neoplastic - drug effects | Neoplasms - pathology | RNA, Small Interfering - administration & dosage | TNF-Related Apoptosis-Inducing Ligand - genetics | X-Linked Inhibitor of Apoptosis Protein - biosynthesis | Transcription factors | Care and treatment | Innovations | Genetic aspects | Drug resistance | Gene expression | Health aspects | Cancer | Studies | Proteins | Immunoglobulins | Chemotherapy | Brain cancer | Rodents | Cytotoxicity | Kinases | Cancer therapies | Tumors
Journal Article
BIOCHEMICAL SOCIETY TRANSACTIONS, ISSN 0300-5127, 2001, Volume 29, Issue Pt 6, pp. 684 - 688
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2004, Volume 279, Issue 49, pp. 51057 - 51067
Taxol (paclitaxel) is known to inhibit cell growth and trigger significant apoptosis in various cancer cells. Although taxol induces apoptosis of cancer cells,... 
DRUG-INDUCED APOPTOSIS | HUMAN NEUROBLASTOMA-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PACLITAXEL-INDUCED APOPTOSIS | LEUKEMIA-CELL LINE | ANTICANCER DRUGS | BREAST-CARCINOMA CELLS | CYTOCHROME-C RELEASE | CHEMOTHERAPEUTIC DRUGS | CASPASE ACTIVATION | OCCURS DOWNSTREAM | Adaptor Proteins, Signal Transducing - chemistry | Caspase 9 | Caspase 8 | Paclitaxel - pharmacology | Reactive Oxygen Species | Coloring Agents - pharmacology | Annexin A5 - pharmacology | Humans | Receptors, Tumor Necrosis Factor, Type I - metabolism | Dose-Response Relationship, Drug | Proto-Oncogene Proteins c-bcl-2 - metabolism | Caspases - metabolism | Flow Cytometry | Transfection | Genes, Dominant | Mitochondrial Proteins - metabolism | Caspase 10 | Caspases - biosynthesis | Caspase 3 | Cell Culture Techniques | Caspase 6 | Cell Line | Cell Survival | Cytochromes c - metabolism | Down-Regulation | Enzyme Inhibitors - pharmacology | Intracellular Signaling Peptides and Proteins | Fas-Associated Death Domain Protein | Mitochondria - metabolism | Tetrazolium Salts - pharmacology | Plasmids - metabolism | Blotting, Western | Poly(ADP-ribose) Polymerases - metabolism | Carrier Proteins - metabolism | Membrane Potentials | Models, Biological | Cell Line, Tumor | Cytosol - metabolism | Adaptor Proteins, Signal Transducing - biosynthesis | Thiazoles - pharmacology | Enzyme Activation | Antineoplastic Agents, Phytogenic - pharmacology | Apoptosis
Journal Article