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International Journal of Pharmaceutics, ISSN 0378-5173, 11/2016, Volume 514, Issue 1, pp. 93 - 102
Journal Article
by Zhao, XY and Liu, XY and Zhang, PC and Liu, YR and Ran, W and Cai, Y and Wang, JY and Zhai, YH and Wang, GR and Ding, YP and Li, YP
ACTA PHARMACEUTICA SINICA B, ISSN 2211-3835, 09/2019, Volume 9, Issue 5, pp. 1050 - 1060
Chemotherapy is among the limited choices approved for the treatment of hepatocellular carcinoma (HCC) at intermediate and advanced stages. Preferential and... 
CANCER-CELLS | Peptide amphiphile | PROTEIN | NANOFIBERS | DRUG-DELIVERY | Hepatocellular carcinoma | DEATH | CARRIERS | SUPRAMOLECULAR FILAMENT HYDROGELS | Self-assembly | THERAPY | Triptolide | PHARMACOLOGY & PHARMACY | Hydrogel | LIPOSOMES | Bel-7402 | CKS2, cyclin kinase subunit-2 | C16-N, C16-GNNQQNYKD-OH | DiR, DiR-labeled DSPE-PEG micelle | Luc, luciferase transfected human HCC cell line Bel-7402 | FI range, fluorescence intensity range | DiI, DiI-labeled C16-N | CAS, Chinese Academy of Sciences | H&E, hematoxylin and eosin | DL, drug loading | ANOVA, analysis of variance | DiR, DiR-labeled C16-N hydrogel | CRE, creatinine | OB glue, EPIGLUs | BUN, blood urea nitrogen | ATL, alanine transaminase | AUC0–13, areas under the curve | DiI, DiI-labeled DSPE-PEG | FI, fluorescence intensity | EE, encapsulation efficiency | T, drug-loaded DSPE-PEG micelles | FBS, fetal bovine serum | DSPE-PEG, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino (polyethylene glycol)-2000] | AURKA, aurora A kinase | AST, aspartate transaminase | C16-N | GEMOX, gemcitabine and oxaliplatin | RFI, relative fluorescence intensity | TEM, transmission electron microscopy | TIR, tumor inhibition rate | HPLC, high-performance liquid chromatography | HFIP, 1,1,1,3,3,3-hexafluoro-2-propanol | DSPE-PEG | TACE, transarterial chemoembolization | T, triptolide-loaded peptide amphiphile-based hydrogel | Tmax, time to reach highest fluorescence intensity | LC–MS, liquid chromatography–mass spectrometry | Akt, protein kinase B | d-Luciferin, (S)-4,5-dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid potassium | Original article | CD, circular dichroism
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 02/2019, Volume 556, pp. 21 - 29
The purpose of this work was to develop a practical and scalable method to encapsulate the hydrophobic antibiotic thiostrepton (TST) in sterically stabilized... 
Drug encapsulation | Co-solvent freeze-drying | Sterically stabilized micelles | Thiostrepton | DSPE-PEG2000 | Antibiotic nanomedicine | DSPE-PEG | BREAST-CANCER | PHOSPHOLIPID MICELLES | PHARMACOLOGY & PHARMACY
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 02/2018, Volume 123, pp. 9 - 19
In the present study, we attempted to develop a lecithin-stabilized micellar drug delivery system (L MDDs) for loading docetaxel (DTX) to enhance its... 
Ultrasonication | Lecithin | DSPE-PEG2K | Lecithin-stabilized micelles | Docetaxel | Index Medicus
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 10/2019, Volume 569, p. 118586
The main objective of this study was to develop a novel self-assembled micelle system to improve the oral bioavailability of the water-insoluble and thermal... 
Supercritical fluid | Oral bioavailability | Soluplus | Germacrone | Self-assembled micelles | DSPE-PEG2000 | DRUG-DELIVERY | BLOCK-COPOLYMER MICELLES | MIXED MICELLES | FORMULATION | Solupins (R) | SOLUBILITY | IN-VITRO | TRANSPORT | DSPE-PEG | PHARMACOLOGY & PHARMACY | CARBON-DIOXIDE | LIPOSOMES | PEGYLATION
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 12/2018, Volume 552, Issue 1-2, pp. 414 - 421
Journal Article
by Chen LC and Chen YC and Su CY and Hong CS and Ho HO and Sheu MT
International Journal of Nanomedicine, ISSN 1178-2013, 04/2016, Volume 2016, Issue default, pp. 1557 - 1566
Ling-Chun Chen,1,* Ying-Chen Chen,1,* Chia-Yu Su,1 Chung-Shu Hong,1 Hsiu-O Ho,1 Ming-Thau Sheu1,2 1School of Pharmacy, College of Pharmacy, 2Clinical Research... 
micelle | Pluronic | DSPE-PEG | quercetin | lecithin
Journal Article
Journal Article
Journal of Chromatography A, ISSN 0021-9673, 10/2012, Volume 1260, pp. 25 - 32
► A simple and cheap method was developed for β -agonists using dSPE with MWCNTs. ► The pH, extraction time, the type and amount of MWCNTs were optimised. ►... 
β2-Agonists | dSPE | MWCNTs | Swine urine | LC–MS/MS | LC-MS/MS | Agonists | DSPE
Journal Article
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 2011, Volume 406, Issue 1, pp. 135 - 144
A novel drug delivery system for beclomethasone dipropionate (BDP) has been constructed through self-assembly of a pegylated phospholipid–polyaminoacid... 
Drug delivery | 1,2-distearoyl- sn-glycero-3-phosphoethanolamine-N-[amino(polyethyleneglycol)2000] (DSPE-PEG 2000-NH 2) | Beclomethasone dipropionate (BDP) | Pulmonary diseases | α,β-Poly(N-2-hydroxyethyl)- dl-aspartamide (PHEA) | Polymeric micelles | α,β-Poly(N-2-hydroxyethyl)-dl-aspartamide (PHEA) | 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethyleneglycol) 2000] (DSPE-PEG | NH | GENE DELIVERY | DRUG-DELIVERY | DEXTRAN | NANOCARRIERS | alpha,beta-Poly(N-2-hydroxyethyl)-DL-aspartamide | BECLOMETHASONE DIPROPIONATE | PHEA | 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethyleneglycol)2000]) (DSPE-PEG-NH2 | PHYSICOCHEMICAL CHARACTERIZATION | SYSTEMS | PHARMACOLOGY & PHARMACY | DERIVATIVES | LIPOSOMES | Hemolysis - drug effects | Beclomethasone - pharmacokinetics | Humans | Polyethylene Glycols - chemistry | Lung - cytology | Drug Carriers - chemistry | Drug Storage | Micelles | Drug Compounding | Lung - metabolism | Molecular Structure | Beclomethasone - chemistry | Cell Line | Cell Survival - drug effects | Beclomethasone - administration & dosage | Peptides - chemistry | Drug Stability | Solubility | Spectrometry, Fluorescence | Phosphatidylethanolamines - chemical synthesis | Drug Carriers - chemical synthesis | Erythrocytes - drug effects | Particle Size | Beclomethasone - pharmacology | Lung - drug effects | Hydrophobic and Hydrophilic Interactions | Polyethylene Glycols - chemical synthesis | Phosphatidylethanolamines - chemistry | Drugs | Beclomethasone dipropionate | Drug delivery systems | Polymers | Vehicles | Steroids
Journal Article
Asian Journal of Pharmaceutical Sciences, ISSN 1818-0876, 05/2018, Volume 13, Issue 3, pp. 289 - 296
Endotoxin can be measured mainly by two methods: the Rabbit Pyrogen Test (RPT) and Limulus Amebocyte Lysate (LAL) assay. We found that a chemotherapeutic drug... 
Micelle | Limulus amebocyte lysate assay | Rabbit pyrogen test | Endotoxin detection | DSPE-mPEG2000 | Irinotecan hydrochloride | DSPE-mPEG
Journal Article
European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 12/2018, Volume 125, pp. 74 - 85
In cholesterol/DSPE-PEG /DPPC systems, nano-disks could evolve between liposomes and spherical micelles in a certain range of PEG-lipids. How cholesterol or... 
Cholesterol content | Imatinib | Membrane fluidity | Interaction | Discoidal micelles | DSPE-PEG2000
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 01/2016, Volume 497, Issue 1-2, pp. 293 - 300
Journal Article