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Journal of Biological Chemistry, ISSN 0021-9258, 11/2003, Volume 278, Issue 46, pp. 46179 - 46187
Cerebral amyloid angiopathy (CAA) due to beta-amyloid (Abeta) is one of the specific pathological features of familial Alzheimer's disease. Abeta mainly... 
APP | DUTCH-TYPE | FIBRILS | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MUTATION | STATE | PRECURSOR PROTEIN | PHORBOL ESTER-BINDING | AGGREGATION | SENILE PLAQUES | cerebral amyloid angiopathy
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 05/2007, Volume 101, Issue 3, pp. 854 - 862
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2016, Volume 291, Issue 23, pp. 12282 - 12293
A missense mutation (T835M) in the uncoordinated-5C (UNC5C) netrin receptor gene increases the risk of late-onset Alzheimer disease (AD) and also the... 
DAP-KINASE | APOPTOSIS | NADPH-OXIDASE | ACTIVATION | DUTCH TYPE | BIOCHEMISTRY & MOLECULAR BIOLOGY | N-TERMINAL KINASE | NEURONAL CELL-DEATH | SKIN PROTEIN | HUMANIN | HEREDITARY CEREBRAL-HEMORRHAGE | Netrin-1 | Humans | NADPH Oxidases - metabolism | Apoptosis - genetics | Neurons - cytology | Nerve Growth Factors - metabolism | Mutation, Missense | Caspases - metabolism | Protein Kinase C - metabolism | Tumor Suppressor Proteins - genetics | Amyloid beta-Protein Precursor - metabolism | Neurons - metabolism | MAP Kinase Kinase Kinase 5 - metabolism | Netrin Receptors | Calcium-Binding Proteins - metabolism | Cell Line | Tumor Suppressor Proteins - metabolism | MAP Kinase Kinase Kinase 5 - genetics | Mitogen-Activated Protein Kinase 8 - metabolism | Death-Associated Protein Kinases - metabolism | Receptors, Cell Surface - metabolism | Signal Transduction - genetics | Blotting, Western | Amyloid beta-Protein Precursor - genetics | Animals | Nerve Growth Factors - genetics | Alzheimer Disease - metabolism | Cell Line, Tumor | Protein Binding | Alzheimer Disease - genetics | Calcium-Binding Proteins - genetics | Receptors, Cell Surface - genetics | Index Medicus | neuronal cell death | neurodegenerative disease | Signal Transduction | Alzheimer disease | apoptosis | UNC5C | amyloid precursor protein (APP) | amyloid beta-independent
Journal Article
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 07/2014, Volume 130, Issue 2, pp. 291 - 300
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 2012, Volume 33, Issue 5, pp. 1010.e1 - 1010.e13
Abstract The Arctic (p. E693G) mutation in the amyloid-β precursor protein (AβPP) facilitates amyloid-β (Aβ) protofibril formation and generates clinical... 
Neurology | Internal Medicine | AβPP mutation | N-terminal truncation | Neuropathology | Familial | β-amyloid protein | Alzheimer's disease | Mass spectrometry | ALPHA-SECRETASE | A beta PP mutation | DUTCH-TYPE | SENSITIVE ELISA | beta-amyloid protein | SPASTIC PARAPARESIS | CORE PROTEIN | NEUROSCIENCES | COTTON WOOL PLAQUES | SENILE PLAQUES | GERIATRICS & GERONTOLOGY | ONSET ALZHEIMER-DISEASE | HEREDITARY CEREBRAL-HEMORRHAGE | TRANSGENIC MICE | Alzheimer Disease - physiopathology | Molecular Weight | Plaque, Amyloid - pathology | Amyloid beta-Peptides - biosynthesis | Humans | Middle Aged | Male | Protein Structure, Tertiary - genetics | Peptide Fragments - biosynthesis | Plaque, Amyloid - genetics | Peptide Fragments - chemistry | Amyloid beta-Protein Precursor - genetics | Protein Isoforms - metabolism | Amyloid beta-Peptides - genetics | Alzheimer Disease - metabolism | Amyloid beta-Protein Precursor - metabolism | Amino Acid Substitution - genetics | Female | Plaque, Amyloid - metabolism | Aged | Amyloid beta-Peptides - chemistry | Alzheimer Disease - genetics | Peptide Fragments - genetics | Protein Isoforms - genetics | Brain | Deposits | Neurodegenerative diseases | Fibrils | Antibodies | Nervous system | beta -Amyloid | Electron microscopy | Cerebral amyloid angiopathy | Aging | Amyloid | Mutation | Plaques | Index Medicus | Basic Medicine | Neurosciences | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Neurovetenskaper
Journal Article
Journal Article
Journal Article
Journal Article
Annals of Neurology, ISSN 0364-5134, 10/2005, Volume 58, Issue 4, pp. 639 - 644
Mutations in A beta PP cause deposition of A beta amyloid fibrils in brain parenchyma and cerebral vessels, resulting in Alzheimer's disease (AD) and/or... 
PATHOGENESIS | STROKE | DEMENTIA | DUTCH TYPE | HEMORRHAGE | ALZHEIMERS-DISEASE | PLAQUES | NEUROSCIENCES | PRECURSOR PROTEIN MUTATION | AGGREGATION | PEPTIDE | CLINICAL NEUROLOGY
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2010, Volume 285, Issue 35, pp. 27144 - 27158
Journal Article