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PloS one, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, p. e0123808
Recently approved chemotherapeutic agents to treat colorectal cancer (CRC) have made some impact; however, there is an urgent need for newer targeted agents... 
GLIOMA-CELLS | G ARREST | ADENOMATOUS POLYPOSIS-COLI | BASE EXCISION-REPAIR | LONG-PATCH | GROWTH ARREST | ALKYLATING-AGENTS | MULTIDISCIPLINARY SCIENCES | POLY(ADP-RIBOSE) POLYMERASE-1 | MISMATCH REPAIR | CELLULAR SENESCENCE | Small Molecule Libraries - pharmacology | Sulfhydryl Compounds - pharmacology | Apoptosis - drug effects | Triazoles - chemistry | Humans | Cellular Senescence - drug effects | Toluene - analogs & derivatives | Dacarbazine - pharmacology | Enzyme Inhibitors - chemistry | Dacarbazine - analogs & derivatives | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Sulfhydryl Compounds - chemistry | DNA Polymerase beta - metabolism | Toluene - pharmacology | DNA Repair - drug effects | Sulfonamides - chemistry | Benzothiazoles - pharmacology | HCT116 Cells | Enzyme Inhibitors - pharmacology | Tumor Suppressor Protein p53 - metabolism | Sulfonamides - pharmacology | Triazoles - pharmacology | Small Molecule Libraries - chemistry | Cell Cycle Checkpoints - drug effects | DNA Damage | Cell Cycle - drug effects | Colorectal Neoplasms - pathology | Senescence | Molecular structure | DNA polymerase | p53 Protein | DNA damage | Genes | Colorectal carcinoma | Colorectal cancer | Cytotoxicity | Drug resistance | Kinases | Cancer therapies | Base excision repair | Alkylation | Molecular docking | Metastases | Analogs | Proteins | Cell cycle | Deoxyribonucleic acid--DNA | Hematology | Blocking | FEN1 protein | Chemotherapy | Displacement activity | Genetic engineering | Temozolomide | DNA-directed DNA polymerase | Cancer | Apoptosis | Deoxyribonucleic acid | DNA
Journal Article
Molecular cancer therapeutics, ISSN 1535-7163, 01/2015, Volume 14, Issue 1, pp. 111 - 119
The cellular responses to two new temozolomide (TMZ) analogues, DP68 and DP86, acting against glioblastoma multiforme (GBM... 
ANTITUMOR DRUG TEMOZOLOMIDE | REPAIR | ACTIVATION | EVOLUTION | THERAPY | ONCOLOGY | MGMT | PRODRUGS | DNA-DAMAGE | REPOPULATION | PROMOTER METHYLATION STATUS | Antineoplastic Agents, Alkylating - chemical synthesis | Ataxia Telangiectasia Mutated Proteins - metabolism | Humans | Neoplasm Recurrence, Local - drug therapy | Antineoplastic Agents, Alkylating - administration & dosage | Brain Neoplasms - metabolism | DNA Repair Enzymes - metabolism | Dacarbazine - analogs & derivatives | Dacarbazine - pharmacokinetics | Glioblastoma - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Aniline Compounds - administration & dosage | DNA Damage - drug effects | Dacarbazine - administration & dosage | Tumor Suppressor Proteins - metabolism | DNA Modification Methylases - metabolism | Neoplasm Recurrence, Local - metabolism | Mice, Inbred C57BL | Heterocyclic Compounds, 2-Ring - administration & dosage | Antineoplastic Agents, Alkylating - pharmacokinetics | Aniline Compounds - pharmacokinetics | Heterocyclic Compounds, 2-Ring - pharmacokinetics | Brain Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Animals | Fanconi Anemia Complementation Group D2 Protein - metabolism | Cell Line, Tumor | Mice | Cell Cycle - drug effects | Glioblastoma - drug therapy | Heterocyclic Compounds, 2-Ring - chemical synthesis | Aniline Compounds - chemical synthesis | Drug Resistance, Neoplasm - drug effects | glioblastoma | DNA damage response | FANCD2 | ATM | Temozolomide | resistance | ATR
Journal Article
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 2015, Volume 10, Issue 3, pp. e0118702 - e0118702
Journal Article
Cancer, ISSN 0008-543X, 2011, Volume 117, Issue 2, pp. 268 - 275
Journal Article
Clinical cancer research, ISSN 1557-3265, 2010, Volume 16, Issue 8, pp. 2443 - 2449
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JAMA : the journal of the American Medical Association, ISSN 0098-7484, 12/2017, Volume 318, Issue 23, pp. 2306 - 2316
Journal Article
Cancer Letters, ISSN 0304-3835, 2014, Volume 358, Issue 2, pp. 144 - 151
Journal Article
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 12/2015, Volume 314, Issue 23, pp. 2535 - 2543
Journal Article
Journal of biomedical science, ISSN 1423-0127, 2015, Volume 22, Issue 1, p. 71
Journal Article