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Neuropharmacology, ISSN 0028-3908, 2005, Volume 48, Issue 8, pp. 1086 - 1096
Exogenously administered cannabinoids are neuroprotective in several different cellular and animal models. In the current study, two cannabinoid CB1 receptor... 
Protein kinase A | Neuroprotection | Cannabinoids | Phosphorylation | FURA-2 | Intracellular calcium | NMDA-excitotoxicity | Ryanodine receptor | Calcium imaging | DEPENDENT PHOSPHORYLATION | calcium imaging FURA-2 | ENDOCANNABINOID SYSTEM | NEUROSCIENCES | CA1 PYRAMIDAL NEURONS | POTASSIUM A-CURRENT | RAT HIPPOCAMPAL-NEURONS | CYCLIC-AMP ACCUMULATION | RECEPTOR MODULATION | SKELETAL-MUSCLE | CA2+-INDUCED CA2+ RELEASE | neuroprotection | cannabinoids | PHARMACOLOGY & PHARMACY | intracellular calcium | ENDOPLASMIC-RETICULUM | ryanodine receptor | protein kinase A | phosphorylation | Okadaic Acid - pharmacology | Calcium - metabolism | Hippocampus - drug effects | Rats, Inbred Strains | Macrocyclic Compounds - pharmacology | N-Methylaspartate - pharmacology | Drug Interactions | Neuroprotective Agents - pharmacology | Receptor, Cannabinoid, CB1 - agonists | Cyclic AMP - analogs & derivatives | Piperidines - pharmacology | Estrenes - pharmacology | Pyrrolidinones - pharmacology | Fetus | Neurons - metabolism | Cell Culture Techniques | Cell Death - drug effects | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Cyclohexanols - pharmacology | Neurons - drug effects | Ryanodine - pharmacology | Pyrazoles - pharmacology | Morpholines - pharmacology | Rats | Dantrolene - pharmacology | Thionucleotides - pharmacology | Naphthalenes - pharmacology | Cyclic AMP - pharmacology | Hippocampus - metabolism | Animals | Benzoxazines - pharmacology | Oxazoles - pharmacology | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Phenols | Adenylate cyclase | Methyl aspartate | Cell research | Calcium channels
Journal Article
Naunyn-Schmiedeberg's Archives of Pharmacology, ISSN 0028-1298, 7/2011, Volume 384, Issue 1, pp. 59 - 70
The present study was aimed at investigating the effect and the possible mechanism of idebenone on endogenous glutamate release in nerve terminals of rat... 
Protein kinase A | Neurosciences | Glutamate release | Cerebral cortex | Biomedicine | Idebenone | Ca v 2.2 (N-type) and Ca v 2.1 (P/Q-type) channels | Synaptosomes | Pharmacology/Toxicology | 2.1 (P/Q-type) channels | 2.2 (N-type) and Ca | OXIDATIVE STRESS | CA2+ ENTRY | N-TYPE | Ca(v)2.2 (N-type) and Ca(v)2.1 (P/Q-type) channels | NEUROTRANSMITTER RELEASE | PRESYNAPTIC MODULATION | CORTICAL-NEURONS | PHARMACOLOGY & PHARMACY | TERMINALS SYNAPTOSOMES | INDUCED NEUROTOXICITY | ENERGY-METABOLISM | BRAIN | Synaptosomes - drug effects | Calcium Channels - metabolism | Maleimides - pharmacology | Male | Nerve Endings - metabolism | Synaptosomes - metabolism | omega-Conotoxins | Cerebral Cortex - cytology | Calcium - deficiency | Ubiquinone - pharmacology | Dose-Response Relationship, Drug | Calcium - antagonists & inhibitors | Isoquinolines - pharmacology | Macrolides - pharmacology | Indoles - pharmacology | Sodium-Calcium Exchanger - antagonists & inhibitors | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | 4-Aminopyridine - pharmacology | Cyclic AMP-Dependent Protein Kinases - metabolism | Membrane Potentials - drug effects | Calcium - pharmacology | Clonazepam - analogs & derivatives | Ubiquinone - analogs & derivatives | Enzyme Inhibitors - pharmacology | Clonazepam - pharmacology | Rats | Protein Kinase C - antagonists & inhibitors | Thiazepines - pharmacology | Dantrolene - pharmacology | Calcium Channel Blockers - pharmacology | Potassium - pharmacology | Sulfonamides - pharmacology | Rats, Sprague-Dawley | Glutamate Plasma Membrane Transport Proteins - antagonists & inhibitors | Pyrroles - pharmacology | Animals | Calcium Signaling - drug effects | Nerve Endings - drug effects | Glutamic Acid - metabolism | Protein Kinase Inhibitors - pharmacology | Carbazoles - pharmacology | Aspartic Acid - pharmacology | Brain | Amino acids | Glutamate | Protein kinases | Nerve endings | Calcium (intracellular) | Calcium channels (N-type) | Calcium channels (voltage-gated) | Cortex | Potassium channels | Calcium influx | Calcium channels (Q-type) | Glutamic acid transporter | Membrane potential | vesicular transporters | Calcium (extracellular) | Na super(+)/Ca super(2+)-exchanging ATPase
Journal Article
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 02/2006, Volume 96, Issue 3, pp. 694 - 705
Expression of brain‐derived neurotrophic factor (BDNF) is sensitive to changes in oxygen availability, suggesting that BDNF may be involved in adaptive... 
intermittent hypoxia | brain‐derived neurotrophic factor release | reactive oxygen species | Intermittent hypoxia | Reactive oxygen species | Brain-derived neurotrophic factor release | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACTIVITY-DEPENDENT RELEASE | RECEPTOR EXPRESSION | HIPPOCAMPAL-NEURONS | CATECHOLAMINE SECRETION | DIFFERENTIAL REGULATION | NEUROSCIENCES | NERVE GROWTH-FACTOR | brain-derived neurotrophic factor release | PC-12 CELLS | PRIMARY SENSORY NEURONS | CEREBRAL-ISCHEMIA | Enzyme-Linked Immunosorbent Assay - methods | Sulpiride - pharmacology | Embryo, Mammalian | Oxidative Stress - physiology | Autocrine Communication - drug effects | Nimodipine - pharmacology | PC12 Cells | Dose-Response Relationship, Drug | Butaclamol - pharmacology | Drug Interactions | Transfection - methods | omega-Conotoxin GVIA - pharmacology | Potassium Chloride - pharmacology | Caffeine - pharmacology | Female | Brain-Derived Neurotrophic Factor - metabolism | Neurons - metabolism | Neurons - drug effects | Cell Differentiation - physiology | Dopamine - metabolism | Boron Compounds - pharmacology | Brain - cytology | Autocrine Communication - physiology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Hydrogen Peroxide - pharmacology | Cadmium - pharmacology | Nerve Growth Factor - pharmacology | Rats | Dantrolene - pharmacology | Calcium Channel Blockers - pharmacology | Pregnancy | Animals | Cell Differentiation - drug effects | Dopamine Antagonists - pharmacology | Thapsigargin - pharmacology | Hypoxia | Oxidative stress | Brain | Oxidation | Neurons | Cells
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 06/2017, Volume 312, Issue 6, pp. C689 - C696
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 01/2013, Volume 145, Issue 1, pp. 286 - 293
Shakuyakukanzoto (SKT) composed of Glycyrrhizae radix (G. radix) and Paeoniae radix (P. radix) has been traditionally used in Japan, Korea and China as an... 
Muscle cramps | Glycyrrhizae radix | Kampo | Antispasmodic | Shakuyakukanzoto | DIABETIC MICE | CARBOPLATIN | CHEMISTRY, MEDICINAL | ISOLIQUIRITIGENIN | PAEONIFLORIN | PLANT SCIENCES | SKELETAL-MUSCLE | INHIBITION | INTEGRATIVE & COMPLEMENTARY MEDICINE | DANTROLENE SODIUM | HEMODIALYSIS-PATIENTS | COMBINATION CHEMOTHERAPY | PHARMACOLOGY & PHARMACY | KANZO-TO | Flavanones - isolation & purification | Rotarod Performance Test - methods | Rats, Wistar | Drugs, Chinese Herbal - pharmacology | Male | Chalcones - isolation & purification | Tibial Nerve - physiology | Dose-Response Relationship, Drug | Coumarins - isolation & purification | Glycyrrhetinic Acid - pharmacology | Chalcone - pharmacology | Chalcone - analogs & derivatives | Muscle, Skeletal - drug effects | Chalcones - pharmacology | Glycyrrhetinic Acid - isolation & purification | Animals, Outbred Strains | Phytotherapy - methods | Muscle Cramp - drug therapy | Drugs, Chinese Herbal - therapeutic use | Electric Stimulation - methods | Parasympatholytics - chemistry | Disease Models, Animal | Muscle Cramp - physiopathology | Glucosides - pharmacology | Flavanones - pharmacology | Glycyrrhiza - chemistry | Rats | Dantrolene - therapeutic use | Dantrolene - pharmacology | Muscle, Skeletal - physiology | Parasympatholytics - pharmacology | Coumarins - pharmacology | Glucosides - isolation & purification | Animals | Paeonia - chemistry | Drugs, Chinese Herbal - chemistry | Muscle Contraction - drug effects | Muscle Contraction - physiology | Plant Roots - chemistry | Mice | Tibial Nerve - drug effects | Drug Combinations | Muscles | Liquid chromatography
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 07/2005, Volume 25, Issue 28, pp. 6702 - 6715
A single axon can innervate multiple targets by collateral branching. Axon branching is thus essential for establishing CNS connectivity. However, surprisingly... 
Cortical development | Calcium transients | CaMKII | Axon branching | Axon guidance | Netrin-1 | FILOPODIA FORMATION | axon branching | GUIDANCE | NERVE GROWTH | CA2+ SIGNALS | NEUROSCIENCES | calcium transients | NEURITE OUTGROWTH | GROWTH CONE MOTILITY | COLORECTAL-CANCER | IN-VIVO | TRANSIENTS | cortical development | axon guidance | netrin-1 | PROTEIN-KINASE-II | MAP Kinase Signaling System - physiology | Nitriles - pharmacology | Recombinant Fusion Proteins - pharmacology | Calcium Signaling - physiology | Recombinant Fusion Proteins - physiology | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - analogs & derivatives | Neurons - cytology | Axons - physiology | Cerebral Cortex - cytology | Nerve Growth Factors - pharmacology | Transfection | Cells, Cultured - ultrastructure | Tumor Suppressor Proteins - genetics | Axons - ultrastructure | Mesocricetus | Flavonoids - pharmacology | Nerve Growth Factors - physiology | Neurons - drug effects | Calcium-Calmodulin-Dependent Protein Kinase Type 2 | Calcium-Calmodulin-Dependent Protein Kinases - physiology | Growth Cones - physiology | Butadienes - pharmacology | Cells, Cultured - drug effects | Cricetinae | Nifedipine - pharmacology | Axons - drug effects | Calcium Channels, L-Type - physiology | Ryanodine Receptor Calcium Release Channel - drug effects | Calcium-Calmodulin-Dependent Protein Kinases - adverse effects | Cytoskeleton - ultrastructure | Dantrolene - pharmacology | Calcium Channel Blockers - pharmacology | Peptides - pharmacology | Tumor Suppressor Proteins - physiology | Animals | MAP Kinase Signaling System - drug effects | Calcium Signaling - drug effects | Nerve Growth Factors - genetics | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - pharmacology | Calcium Channels, L-Type - drug effects | Chickens | Tumor Suppressor Proteins - pharmacology | Protein Kinase Inhibitors - pharmacology | Growth Cones - drug effects | Ryanodine Receptor Calcium Release Channel - physiology | Plasticity | Development | Repair
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 11/2012, Volume 303, Issue 9, pp. L824 - L833
Dahan D, Ducret T, Quignard J, Marthan R, Savineau J, Esteve E. Implication of the ryanodine receptor in TRPV4-induced calcium response in pulmonary arterial... 
Calcium signaling | Type 4 vanilloid transient receptor potential subfamily | Dantrolene | Transient receptor potential channel | Pulmonary hypertension | type 4 vanilloid transient receptor potential subfamily | POTENTIAL CHANNELS | PHYSIOLOGY | pulmonary hypertension | CA2+ RELEASE | calcium signaling | TRP CHANNELS | CA-2+ RELEASE CHANNEL | CARDIAC-MUSCLE | SARCOPLASMIC-RETICULUM | RESPIRATORY SYSTEM | GENE-EXPRESSION | dantrolene | BINDING-SITES | HYPERTENSION | transient receptor potential channel | DANTROLENE INHIBITION | Rats, Wistar | Male | Ryanodine Receptor Calcium Release Channel - metabolism | Hypoxia - metabolism | Macrocyclic Compounds - pharmacology | Cell Hypoxia | TRPV Cation Channels - metabolism | Phorbols - pharmacology | TRPV Cation Channels - antagonists & inhibitors | Muscle Relaxants, Central - pharmacology | Caffeine - pharmacology | Myocytes, Smooth Muscle - metabolism | Calcium Signaling | Ryanodine - pharmacology | TRPV Cation Channels - agonists | Cells, Cultured | Morpholines - pharmacology | Rats | Hypertension, Pulmonary - metabolism | Hypoxia - complications | Pulmonary Artery - physiopathology | Dantrolene - pharmacology | Patch-Clamp Techniques | Pyrroles - pharmacology | Animals | Muscle Contraction - drug effects | Calcium Channel Agonists - pharmacology | Oxazoles - pharmacology | In Vitro Techniques | Hypertension, Pulmonary - etiology | Pulmonary Artery - pathology | Calcium channels | Physiological aspects | Smooth muscle | Muscle cells | Hypoxia | Development and progression | Health aspects | Pulmonary artery
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, p. e0132017
Decidualization of human endometrial stroma and gland development is mediated through cyclic AMP (cAMP), but the role of intracellular calcium ion (Ca2+) on... 
MENSTRUAL-CYCLE | CA2+ ENTRY | HUMAN DECIDUAL CELLS | ADENYLYL CYCLASES | MULTIDISCIPLINARY SCIENCES | GLANDULAR CELLS | PROLACTIN | DIFFERENTIATION | STROMAL CELLS | BINDING PROTEIN | CAMP | Biomarkers - metabolism | Cell Line | Calcium - pharmacology | Embryo Implantation - drug effects | Colforsin - pharmacology | Dinoprostone - biosynthesis | Humans | Stromal Cells - metabolism | Ions | Ryanodine Receptor Calcium Release Channel - metabolism | Chelating Agents - pharmacology | Dantrolene - pharmacology | Calcium Channel Blockers - pharmacology | Decidua - metabolism | Cyclic AMP - pharmacology | Models, Biological | Cyclooxygenase 2 - metabolism | Stromal Cells - drug effects | Female | Calcium Channels, L-Type - metabolism | Decidua - drug effects | Endometrium - cytology | Alamethicin - pharmacology | Ionophores - pharmacology | Calcium channels | Pituitary hormones | Ionophores | Protein binding | Nifedipine | Ionomycin | Transcription | Calcium | Laboratories | Epithelial cells | Insulin-like growth factor-binding protein 1 | Variations | Prostaglandin E2 | Intracellular signalling | Insulin-like growth factors | Calcium ionophores | Kinases | Calcium influx | Prostaglandin endoperoxide synthase | Calcium signalling | Proteins | Signal transduction | Prolactin | Physiology | Endometrium | Medical research | Calcium (intracellular) | Menstruation | Calcium channels (voltage-gated) | Cyclic AMP | Implantation | Pharmacology | Decidua | Breeding of animals | Gene expression | Embryos | Pharmacy | Calcium channels (L-type) | Forskolin | Cyclooxygenase-2 | Intracellular
Journal Article
Journal Article