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Journal Article
British journal of cancer, ISSN 0007-0920, 2017, Volume 117, Issue 12, pp. 1777 - 1786
Nuclear internalisation | Acquired resistance | IGF-1R | Colorectal cancer | BRAF mutation | Life Sciences & Biomedicine | Oncology | Science & Technology | Leucovorin - administration & dosage | Receptor, IGF Type 1 - metabolism | Molecular Chaperones - metabolism | Proto-Oncogene Proteins p21(ras) - genetics | Colorectal Neoplasms - genetics | Humans | Middle Aged | Panitumumab | Drug Resistance, Neoplasm | Male | Protein Inhibitors of Activated STAT - metabolism | Protein Transport - drug effects | Cell Nucleus - metabolism | Colorectal Neoplasms - drug therapy | Protein Inhibitors of Activated STAT - genetics | Camptothecin - administration & dosage | Camptothecin - analogs & derivatives | Cell Survival - drug effects | Bevacizumab - administration & dosage | Antibodies, Monoclonal - pharmacology | HCT116 Cells | Curcumin - pharmacology | Molecular Chaperones - genetics | Pyrimidines - pharmacology | Dasatinib - pharmacology | Signal Transduction - drug effects | Sorafenib | Fluorouracil - pharmacology | Niacinamide - analogs & derivatives | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Molecular Targeted Therapy | Organoplatinum Compounds - pharmacology | Organoplatinum Compounds - administration & dosage | Fluorouracil - administration & dosage | Oxaliplatin | Female | Antineoplastic Agents - pharmacology | Gene Silencing | Fatty Acids, Unsaturated - pharmacology | HT29 Cells | Pyrroles - pharmacology | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Cetuximab - administration & dosage | Aged | Phenylurea Compounds - pharmacology | Niacinamide - pharmacology | Colorectal Neoplasms - pathology | Index Medicus | Translational Therapeutics | nuclear internalisation | colorectal cancer | acquired resistance
Journal Article
British journal of pharmacology, ISSN 0007-1188, 10/2009, Volume 158, Issue 4, pp. 1153 - 1164
ADME-Tox | CML | TKI | ABCB1 | Bcr-Abl | MDR | ABCG2 | ADME‐Tox | Bcr‐Abl | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Biological and medical sciences | Pharmacology. Drug treatments | Medical sciences | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Thiazoles - metabolism | Nitriles - pharmacology | Aniline Compounds - metabolism | Protein-Tyrosine Kinases - metabolism | Drug Resistance, Multiple - drug effects | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Substrate Specificity | Neoplasm Proteins - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Thiazoles - therapeutic use | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Neoplasm Proteins - metabolism | Cyclosporins - pharmacology | Pyrimidines - metabolism | Quinolines - pharmacology | Dose-Response Relationship, Drug | ATP-Binding Cassette Transporters - metabolism | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Dasatinib | Nitriles - metabolism | Aniline Compounds - pharmacology | Pyrimidines - pharmacology | Neoplasms - drug therapy | Quinolines - metabolism | Pyrimidines - therapeutic use | K562 Cells | Cell Line, Tumor | ATP Binding Cassette Transporter, Sub-Family B | Protein Kinase Inhibitors - pharmacology | Quinolines - therapeutic use | Thiazoles - pharmacology | Aniline Compounds - therapeutic use | Fusion Proteins, bcr-abl - metabolism | ATP-Binding Cassette Transporters - antagonists & inhibitors | Nitriles - therapeutic use | Index Medicus | Research Papers
Journal Article
Cancer letters, ISSN 0304-3835, 2012, Volume 320, Issue 1, pp. 104 - 110
Journal Article
JNCI : Journal of the National Cancer Institute, ISSN 0027-8874, 11/2011, Volume 103, Issue 22, pp. 1665 - 1675
Life Sciences & Biomedicine | Oncology | Science & Technology | Tumors of the urinary system | Urinary tract. Prostate gland | Nephrology. Urinary tract diseases | Biological and medical sciences | Medical sciences | Tumors | Cancer Vaccines - pharmacology | Humans | Male | Antineoplastic Agents - therapeutic use | Bevacizumab | Prostatic Neoplasms - immunology | RANK Ligand - pharmacology | Receptors, Androgen - drug effects | Treatment Failure | Prostatic Neoplasms - drug therapy | Phenylthiohydantoin - pharmacology | Tumor Microenvironment - drug effects | Dasatinib | Antibodies, Monoclonal - pharmacology | Angiogenesis Inhibitors - pharmacology | Clusterin - pharmacology | Pyrimidines - pharmacology | Denosumab | Prostate-Specific Antigen - blood | Orchiectomy | Signal Transduction - drug effects | Anilides - pharmacology | Mice | Receptor Cross-Talk - drug effects | Endothelin-1 - antagonists & inhibitors | Immunotherapy - methods | Taxoids - pharmacology | Ipilimumab | Tissue Extracts - pharmacology | Bone Remodeling - drug effects | Pyrrolidines - pharmacology | Antibodies, Monoclonal, Humanized - pharmacology | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Molecular Targeted Therapy - methods | Prostatic Neoplasms - pathology | Antineoplastic Agents, Hormonal - pharmacology | Androstenols - pharmacology | Androstenes | Clinical Trials as Topic | Mice, SCID | Phenylthiohydantoin - analogs & derivatives | Biomarkers, Tumor - blood | Xenograft Model Antitumor Assays | Cancer Vaccines - immunology | Pyrroles - pharmacology | Animals | RANK Ligand - antagonists & inhibitors | Pyridines - pharmacology | Thiazoles - pharmacology | Immune response | Development and progression | Cellular signal transduction | Research | Drug therapy | Health aspects | Prostate cancer | Risk factors | Metastasis | Cancer therapies | Index Medicus | Review
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 05/2009, Volume 119, Issue 5, pp. 1109 - 1123
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Transcription Factor CHOP - genetics | Neoplastic Stem Cells - cytology | Gene Expression - drug effects | Calcium - metabolism | Gene Expression - genetics | Microtubule-Associated Proteins - metabolism | Neoplastic Stem Cells - drug effects | Humans | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Endoplasmic Reticulum - metabolism | Antineoplastic Agents - therapeutic use | Autophagy - physiology | Thiazoles - therapeutic use | Autophagy - drug effects | Chloroquine - pharmacology | Neoplastic Stem Cells - metabolism | RNA Interference | Endoplasmic Reticulum - drug effects | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | Macrolides - pharmacology | Antineoplastic Agents - pharmacology | Cell Death - drug effects | Dasatinib | Chloroquine - therapeutic use | Piperazines - therapeutic use | Pyrimidines - pharmacology | Imatinib Mesylate | Piperazines - pharmacology | Mice, Inbred C3H | Xenograft Model Antitumor Assays | Fusion Proteins, bcr-abl - genetics | Animals | Cell Death - physiology | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | Fusion Proteins, bcr-abl - antagonists & inhibitors | Cell Line, Tumor | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - metabolism | Mice | Protein Kinase Inhibitors - pharmacology | Thiazoles - pharmacology | Benzamides | Macrolides - therapeutic use | Protein-Tyrosine Kinases - antagonists & inhibitors | Causes of | Physiological aspects | Genetic aspects | Chronic myeloid leukemia | Research | Drug therapy | Phagocytosis | Index Medicus | Abridged Index Medicus
Journal Article
Leukemia, ISSN 0887-6924, 03/2015, Volume 29, Issue 3, pp. 586 - 597
Oncology | Life Sciences & Biomedicine | Hematology | Science & Technology | Leukocytes, Mononuclear - metabolism | Small Molecule Libraries - pharmacology | Phosphorylation | Luciferases - metabolism | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Humans | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics | STAT3 Transcription Factor - chemistry | Luciferases - genetics | Neoplastic Stem Cells - metabolism | Aminosalicylic Acids - chemistry | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | Neoplastic Stem Cells - pathology | Antineoplastic Agents - pharmacology | Benzamides - pharmacology | Genes, Reporter | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Protein Structure, Tertiary | Dasatinib | Aminosalicylic Acids - pharmacology | Leukocytes, Mononuclear - drug effects | Signal Transduction | Sulfonamides - chemistry | Small Molecule Libraries - chemical synthesis | Gene Expression Regulation, Leukemic | Pyrimidines - pharmacology | Sulfonamides - pharmacology | Drug Discovery | Imatinib Mesylate | Piperazines - pharmacology | Leukocytes, Mononuclear - pathology | Small Molecule Libraries - chemistry | Sulfonamides - chemical synthesis | Fusion Proteins, bcr-abl - genetics | Aminosalicylic Acids - chemical synthesis | Fusion Proteins, bcr-abl - antagonists & inhibitors | Cell Line, Tumor | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - metabolism | Molecular Docking Simulation | Protein Kinase Inhibitors - pharmacology | Thiazoles - pharmacology | STAT3 Transcription Factor - antagonists & inhibitors | Fusion Proteins, bcr-abl - metabolism | Drug Resistance, Neoplasm - drug effects | Enzyme inhibitors | Gene mutations | Patient outcomes | Development and progression | Genetic aspects | Chronic myeloid leukemia | Drug therapy | Health aspects | Enzymes | Care and treatment | Regulation | Drug resistance | Deuterium | BCR protein | Therapy | Transcription | Leukemia | Fluorescence | High-throughput screening | Molecular dynamics | Activation | Lethality | Kinases | Assaying | Chromosomes | Protein-tyrosine kinase | Tyrosine | Fluorescence polarization | Computer simulation | Myeloid leukemia | Stat3 protein | Progenitor cells | Patients | Philadelphia chromosome | Organic chemistry | Inhibitors | Stem cells | Computer applications | Mutation | Index Medicus
Journal Article