X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (2859) 2859
Publication (459) 459
Book Review (66) 66
Book / eBook (22) 22
Book Chapter (18) 18
Newsletter (10) 10
Conference Proceeding (3) 3
Magazine Article (3) 3
Dissertation (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (1859) 1859
apoptosis (1775) 1775
index medicus (1694) 1694
animals (1440) 1440
biochemistry & molecular biology (1341) 1341
cell biology (1306) 1306
cell death (994) 994
signal transduction (852) 852
proteins (813) 813
mice (716) 716
activation (643) 643
cell-death (642) 642
research (564) 564
research article (539) 539
multidisciplinary sciences (472) 472
apoptosis - drug effects (463) 463
nf-kappa-b (461) 461
cancer (458) 458
medicine (454) 454
biology (439) 439
kinases (439) 439
oncology (419) 419
gene expression (406) 406
biochemistry (404) 404
caspases - metabolism (394) 394
science (378) 378
death (369) 369
apoptosis - physiology (356) 356
phosphorylation (356) 356
cell line, tumor (343) 343
physiological aspects (335) 335
caspase (312) 312
cell line (310) 310
genetic aspects (309) 309
article (299) 299
inflammation (297) 297
protein (296) 296
immunology (291) 291
genetics & heredity (290) 290
mitochondria (290) 290
carrier proteins - metabolism (281) 281
health aspects (277) 277
amino acid sequence (268) 268
protein binding (268) 268
expression (267) 267
mutation (266) 266
molecular sequence data (259) 259
review (254) 254
autophagy (243) 243
female (239) 239
male (228) 228
biology and life sciences (224) 224
oxidative stress (220) 220
adaptor proteins, signal transducing (217) 217
analysis (211) 211
cells, cultured (205) 205
hela cells (200) 200
genetics (197) 197
enzyme activation (196) 196
fas-associated death domain protein (193) 193
programmed cell-death (193) 193
genes (192) 192
protein structure, tertiary (190) 190
fas receptor - metabolism (189) 189
cell survival (188) 188
in-vivo (186) 186
signal transduction - drug effects (186) 186
caspase 8 (182) 182
signaling (182) 182
caspase-8 (179) 179
molecular biology (179) 179
rodents (178) 178
mitochondria - metabolism (177) 177
models, biological (177) 177
receptor (175) 175
cell cycle (172) 172
transfection (172) 172
inhibition (167) 167
apoptosis - genetics (166) 166
signal transduction - physiology (166) 166
cytokines (163) 163
ligands (162) 162
medicine and health sciences (162) 162
induced apoptosis (161) 161
nf-kappa b - metabolism (161) 161
caspase 8 - metabolism (158) 158
physiology (157) 157
receptors (155) 155
cell processes (152) 152
mice, inbred c57bl (151) 151
mice, knockout (151) 151
tumor-necrosis-factor (151) 151
fas (149) 149
adaptor proteins, signal transducing - metabolism (148) 148
cells (148) 148
rats (148) 148
caspase 9 (144) 144
cell proliferation (143) 143
cytochrome-c (142) 142
necrosis (138) 138
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (12) 12
UofT at Scarborough - Stacks (4) 4
Collection Dvlpm't (Acquisitions) - Vendor file (3) 3
UofT at Mississauga - Stacks (3) 3
Online Resources - Online (2) 2
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (2) 2
Collection Dvlpm't (Acquisitions) - Closed Orders (1) 1
Earth Sciences (Noranda) - Circulation Desk (1) 1
Earth Sciences (Noranda) - Oversize (1) 1
Earth Sciences (Noranda) - Stacks (1) 1
Gerstein Science - Circulation Desk (1) 1
Gerstein Science - Reserve desk (1) 1
Holland Bloorview Kids Rehabilitation - Stacks (1) 1
St. Michael's College (John M. Kelly) - 2nd Floor (1) 1
Trinity College (John W Graham) - Stacks (1) 1
UofT at Mississauga - Circulation Desk (1) 1
Victoria University E.J. Pratt - Circulation Desk (1) 1
Victoria University E.J. Pratt - Oversize (1) 1
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Molecular Cell, ISSN 1097-2765, 10/2016, Volume 64, Issue 2, pp. 236 - 250
Caspase-8 activation can be triggered by death receptor-mediated formation of the death-inducing signaling complex (DISC) and by the inflammasome adaptor ASC.... 
caspase-8 | DED | MC159 | cFLIP | DISC | Fas | death domain | FADD | vFLIP | filament | APOPTOSIS | ACTIVATION | IMMUNE-SYSTEM | INHIBITION | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | UNIFIED MODEL | EFFECTOR DOMAIN | CELL-DEATH | CELL BIOLOGY | Death Domain Receptor Signaling Adaptor Proteins - chemistry | Apoptosis - drug effects | Cytoskeletal Proteins - genetics | Humans | Caspase 8 - metabolism | Caspase 8 - chemistry | CASP8 and FADD-Like Apoptosis Regulating Protein - chemistry | Death Domain Receptor Signaling Adaptor Proteins - genetics | Recombinant Fusion Proteins - metabolism | Viral Proteins - metabolism | Caspase 8 - genetics | Transfection | Cytoskeletal Proteins - metabolism | Protein Interaction Domains and Motifs | Binding Sites | CASP8 and FADD-Like Apoptosis Regulating Protein - metabolism | Death Effector Domain | Fas-Associated Death Domain Protein - genetics | Amino Acid Sequence | Protein Conformation, alpha-Helical | Gene Expression | CASP8 and FADD-Like Apoptosis Regulating Protein - genetics | Jurkat Cells | Viral Proteins - chemistry | Fas-Associated Death Domain Protein - metabolism | Viral Proteins - genetics | fas Receptor - pharmacology | Cytoskeletal Proteins - chemistry | Recombinant Fusion Proteins - chemistry | Plasmids - metabolism | Fas-Associated Death Domain Protein - chemistry | Cryoelectron Microscopy | Sequence Homology, Amino Acid | Sequence Alignment | Protein Conformation, beta-Strand | CARD Signaling Adaptor Proteins | Plasmids - chemistry | Protein Binding | Recombinant Fusion Proteins - genetics | Death Domain Receptor Signaling Adaptor Proteins - metabolism | Autoimmunity | Medical colleges | Skin diseases | Molecular biology | Analysis | Index Medicus
Journal Article
Journal Article
Immunological Reviews, ISSN 0105-2896, 01/2009, Volume 227, Issue 1, pp. 161 - 175
Initiation of the innate immune response requires agonist recognition by a pathogen recognition receptor. Following ligand binding, conformational... 
Signal transduction | Caspase recruitment domain | Homotypic protein interaction | Toll-interleukin-1 receptor | Death domain | TOLL-LIKE-RECEPTORS | signal transduction | CRYSTAL-STRUCTURE | homotypic protein interaction | IMMUNOLOGY | BACTERIAL PEPTIDOGLYCAN | caspase recruitment domain | MURAMYL DIPEPTIDE | death domain | CASPASE-RECRUITMENT DOMAIN | INTERLEUKIN-1 RECEPTOR | NF-KAPPA-B | PATTERN-RECOGNITION RECEPTORS | KINASE IRAK FAMILY | CARD Signaling Adaptor Proteins - immunology | Death Domain Receptor Signaling Adaptor Proteins - chemistry | Death Domain Receptor Signaling Adaptor Proteins - immunology | Infection - immunology | Humans | Toll-Like Receptors - immunology | Toll-Like Receptors - chemistry | Structure-Activity Relationship | Immunity, Innate | Host-Pathogen Interactions - immunology | Protein Transport - immunology | Signal Transduction - immunology | Allosteric Regulation - immunology | CARD Signaling Adaptor Proteins - metabolism | Receptors, Cytoplasmic and Nuclear - immunology | Animals | Receptors, Cytoplasmic and Nuclear - chemistry | Helminth Proteins - immunology | CARD Signaling Adaptor Proteins - chemistry | Protein Interaction Domains and Motifs | Protein Processing, Post-Translational - immunology | Helminth Proteins - metabolism | Death Domain Receptor Signaling Adaptor Proteins - metabolism | Proteins
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 02/2015, Volume 427, Issue 4, pp. 737 - 752
Homotypic death domain (DD)–DD interactions are important in the assembly of oligomeric signaling complexes such as the PIDDosome that acts as a platform for... 
ILV-labeling | death domain | TROSY NMR | protein complex | spectral complexity | Protein complex | Spectral complexity | Death domain | CASPASE-2 ACTIVATION | DOMAIN | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUPRAMOLECULAR COMPLEXES | METHYL-GROUPS | MOLECULAR-WEIGHT PROTEINS | STRUCTURAL BASIS | PIDD | MAGNETIC-RESONANCE CHARACTERIZATION | Protein Structure, Tertiary | Amino Acid Sequence | CRADD Signaling Adaptor Protein - metabolism | Death Domain Receptor Signaling Adaptor Proteins - chemistry | Humans | Models, Molecular | Crystallography, X-Ray | Multiprotein Complexes - metabolism | Multiprotein Complexes - ultrastructure | Spectrometry, Mass, Electrospray Ionization | CRADD Signaling Adaptor Protein - ultrastructure | Death Domain Receptor Signaling Adaptor Proteins - ultrastructure | CRADD Signaling Adaptor Protein - genetics | Nuclear Magnetic Resonance, Biomolecular | Nuclear magnetic resonance spectroscopy | Mass spectrometry | Structure | Crystals | MS, mass spectrometry | HSQC, heteronuclear single quantum coherence | CARD, caspase recruitment domain | TCEP, tris(2-carboxyethyl)phosphine | nanoESI, nanoflow electrospray ionization | MALS, multi-angle light scattering | SEC, size-exclusion chromatography | 2D, two-dimensional | DD, death domain | TROSY, transverse relaxation optimized spectroscopy
Journal Article
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 1/2012, Volume 40, Issue D1, pp. D331 - D336
Journal Article
Open Biology, ISSN 2046-2441, 2012, Volume 2, Issue 8, p. 120071
Journal Article