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Cell, ISSN 0092-8674, 06/2016, Volume 165, Issue 7, pp. 1698 - 1707
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 12/2016, Volume 139, Issue 5, p. 689
  Read the highlighted article 'Reductions in the mitochondrial enzyme [alpha]-ketoglutarate dehydrogenase complex in neurodegenerative disease - beneficial or... 
Dehydrogenases
Journal Article
Journal Article
Journal of Biochemical and Molecular Toxicology, ISSN 1095-6670, 10/2017, Volume 31, Issue 10, pp. e21954 - n/a
In this study, we investigated the effect of astaxanthin (Ast) and aluminum (Al) on the erythrocyte glucose‐6‐phosphate dehydrogenase (G6PD) and... 
inhibition | enzyme purification | aluminum | rat erythrocyte | glucose‐6‐phosphate dehydrogenase (G6PD); 6‐phosphogluconate dehydrogenase (6PGD) | astaxanthin | glucose-6-phosphate dehydrogenase (G6PD); 6-phosphogluconate dehydrogenase (6PGD) | OXIDATIVE STRESS | 6-phosphogluconate dehydrogenase (6PGD) | glucose-6-phosphate dehydrogenase (G6PD) | BIOCHEMISTRY & MOLECULAR BIOLOGY | CAROTENOIDS | 6-PHOSPHOGLUCONATE DEHYDROGENASE | GLUCOSE-6-PHOSPHATE-DEHYDROGENASE | MICROALGAE | CARDIOVASCULAR-DISEASE | DANTROLENE SODIUM | CARDAX(TM) | TOXICOLOGY | CARDIOPROTECTION | Xanthophylls - chemistry | Chlorides - pharmacology | Phosphogluconate Dehydrogenase - chemistry | Enzyme Inhibitors - pharmacology | Rats | Chlorides - chemistry | Phosphogluconate Dehydrogenase - metabolism | Animals | Glucosephosphate Dehydrogenase - chemistry | Aluminum Compounds - chemistry | Enzyme Inhibitors - chemistry | Glucosephosphate Dehydrogenase - antagonists & inhibitors | Glucosephosphate Dehydrogenase - metabolism | Xanthophylls - pharmacology | Aluminum Compounds - pharmacology | Erythrocytes - enzymology | Phosphogluconate Dehydrogenase - antagonists & inhibitors | Phosphates | Enzymes | Dehydrogenases | Enzyme activity | Aluminum | Astaxanthin | Aluminum chloride | Dehydrogenase | ADP | Glucose 6 phosphate dehydrogenase | Glucose dehydrogenase | Aluminum chlorides | Chloride | Enzymatic activity | Rodents | In vivo methods and tests | Inhibition | Glucosephosphate dehydrogenase | Index Medicus
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 2006, Volume 248, Issue 1, pp. 126 - 135
Endometrial cancer is the most common malignancy of the female genital tract. Its incidence correlates with prolonged estrogen stimulation unopposed by... 
Short-chain dehydrogenase reductase | 17β-Hydroxysteroid dehydrogenase | 20α-Hydroxysteroid dehydrogenase | Aldo-keto reductase | 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE-2 | HYDROXYSTEROID DEHYDROGENASES | ER-BETA | short-chain dehydrogenase reductase | RECEPTOR-B | CELL BIOLOGY | INACTIVATION | CARCINOGENESIS | KETO REDUCTASE SUPERFAMILY | ENDOCRINOLOGY & METABOLISM | 20 alpha-hydroxysteroid dehydrogenase | aldo-keto reductase | 17 beta-hydroxysteroid dehydrogenase | EXPRESSION | CARCINOMA | HORMONES | Humans | Endometrial Neoplasms - metabolism | Hydroxyprostaglandin Dehydrogenases - metabolism | Estrogens - analysis | Endometrial Neoplasms - genetics | Isoenzymes - metabolism | 3-Hydroxysteroid Dehydrogenases - metabolism | Female | Progesterone - biosynthesis | Tumor Cells, Cultured | Estradiol - biosynthesis | Endometrium - metabolism | Progesterone - analysis | 20-Hydroxysteroid Dehydrogenases - genetics | Estrogens - biosynthesis | Endometrial Neoplasms - chemistry | Oxidoreductases - metabolism | Isoenzymes - genetics | 20-Hydroxysteroid Dehydrogenases - metabolism | Hydroxyprostaglandin Dehydrogenases - genetics | Endometrium - chemistry | Animals | Aldo-Keto Reductase Family 1 Member C3 | Estradiol Dehydrogenases | 3-Hydroxysteroid Dehydrogenases - genetics | 17-Hydroxysteroid Dehydrogenases - metabolism | Enzymes | Care and treatment | Endometrial cancer | Phenols | Hormones | Progesterone | Estradiol | Cancer | Index Medicus
Journal Article
Angewandte Chemie - International Edition, ISSN 1433-7851, 01/2013, Volume 52, Issue 5, pp. 1437 - 1440
Journal Article
Oncology Reports, ISSN 1021-335X, 03/2017, Volume 37, Issue 4, pp. 2025 - 2032
Resistance to anticancer medications often leads to poor outcomes. The present study explored an effective approach for enhancing chemotherapy targeted against... 
aldo-keto reductase | cisplatin | mefenamic acid | 5-FU | Cisplatin, 5-FU | Mefenamic acid | Aldo-keto reductase | HUMAN OVARIAN | AKR1C3 | CISPLATIN RESISTANCE | TUMOR-CELLS | CHEMOTHERAPY | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE | LUNG-CANCER | CARCINOMA CELL-LINE | ONCOLOGY | SUPERFAMILY | EXPRESSION | 20-Hydroxysteroid Dehydrogenases - biosynthesis | 3-Hydroxysteroid Dehydrogenases - biosynthesis | 20-Hydroxysteroid Dehydrogenases - genetics | Humans | Hydroxyprostaglandin Dehydrogenases - biosynthesis | Hydroxysteroid Dehydrogenases - genetics | Hydroxyprostaglandin Dehydrogenases - genetics | Cisplatin - administration & dosage | Neoplasms - drug therapy | 3-Hydroxysteroid Dehydrogenases - antagonists & inhibitors | Hydroxyprostaglandin Dehydrogenases - antagonists & inhibitors | Fluorouracil - administration & dosage | 20-Hydroxysteroid Dehydrogenases - antagonists & inhibitors | Neoplasms - genetics | Aldo-Keto Reductase Family 1 Member C3 | Mefenamic Acid - administration & dosage | Hydroxysteroid Dehydrogenases - antagonists & inhibitors | Hydroxysteroid Dehydrogenases - biosynthesis | Gene Expression Regulation, Neoplastic - drug effects | HeLa Cells | Oxidoreductases | 3-Hydroxysteroid Dehydrogenases - genetics | Neoplasms - pathology | Drug Resistance, Neoplasm - drug effects | Care and treatment | Patient outcomes | Genetic aspects | Drug resistance | Gene expression | Health aspects | Methods | Cancer | Studies | Enzymes | Oxidative stress | Chemotherapy | Genes | Rodents | Prostate | Experiments | Cancer therapies | Deoxyribonucleic acid--DNA | Apoptosis | Index Medicus
Journal Article
Journal of Steroid Biochemistry and Molecular Biology, ISSN 0960-0760, 2011, Volume 125, Issue 1, pp. 148 - 161
Journal Article
American Journal of Physiology - Endocrinology And Metabolism, ISSN 0193-1849, 02/2009, Volume 296, Issue 2, pp. 244 - 255
The objective was to examine pathways of androgen metabolism in abdominal adipose tissue in women. Abdominal subcutaneous (SC) and omental (OM) adipose tissue... 
Omental visceral fat | Adipocyte differentiation | Short-chain dehydrogenases | Aldo-keto reductases | Estrogen | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASES | AROMATASE-ACTIVITY | estrogen | PHYSIOLOGY | short-chain dehydrogenases | adipocyte differentiation | omental visceral fat | HUMAN PREADIPOCYTES | 20-ALPHA-HYDROXYSTEROID DEHYDROGENASE | ESTROGEN-RECEPTOR-BETA | OBESITY | 17-BETA-HYDROXYSTEROID-DEHYDROGENASE | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | aldo-keto reductases | DIFFERENTIATION | STROMAL CELLS | Adipose Tissue - physiology | Humans | Middle Aged | Gene Expression Regulation, Enzymologic - physiology | Hydroxyprostaglandin Dehydrogenases - metabolism | Adipogenesis - physiology | Adipose Tissue - metabolism | Subcutaneous Fat - metabolism | Omentum - enzymology | 3-Hydroxysteroid Dehydrogenases - metabolism | Adult | Female | Hydroxysteroid Dehydrogenases - metabolism | Metabolic Networks and Pathways - physiology | Body Fat Distribution | Adipogenesis - genetics | Cells, Cultured | Hydroxysteroid Dehydrogenases - genetics | Omentum - metabolism | Hydroxyprostaglandin Dehydrogenases - genetics | Abdominal Fat - metabolism | Metabolic Networks and Pathways - genetics | Aldo-Keto Reductase Family 1 Member C3 | Estradiol Dehydrogenases | Models, Biological | 17-Hydroxysteroid Dehydrogenases - genetics | Abdominal Fat - enzymology | Adipose Tissue - enzymology | 3-Hydroxysteroid Dehydrogenases - genetics | Androgens - metabolism | 17-Hydroxysteroid Dehydrogenases - metabolism | Subcutaneous Fat - enzymology | Women | Tissue | Enzymes | Androgens | Body fat | Metabolism | Ribonucleic acid--RNA | Index Medicus
Journal Article
Biochemical Journal, ISSN 0264-6021, 12/2011, Volume 440, Issue 3, pp. 335 - 344
Human AKR (aldo-keto reductase) 1C proteins (AKR1C1-AKR1C4) exhibit relevant activity with steroids, regulating hormone signalling at the pre-receptor level.... 
Aldo-keto reductase (AKR) | Retinaldehyde | Proliferation | Retinoic acid | Retinol | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASES | proliferation | BIOCHEMISTRY & MOLECULAR BIOLOGY | aldo-keto reductase (AKR) | retinaldehyde | STEROID-HORMONE | DIHYDRODIOL DEHYDROGENASE | retinol | SHORT-CHAIN DEHYDROGENASES/REDUCTASES | BREAST-CANCER CELLS | retinoic acid | METABOLISM | REVEALS ROLES | MCF-7 CELLS | PROSTAGLANDIN-F SYNTHASE | Vitamin A - pharmacology | Vitamin A - chemistry | Cell Proliferation | Hydroxysteroid Dehydrogenases - chemistry | Humans | Transcriptional Activation | 20-Hydroxysteroid Dehydrogenases - chemistry | Retinaldehyde - chemistry | Substrate Specificity | Hydroxyprostaglandin Dehydrogenases - metabolism | Oxidoreductases - chemistry | 3-Hydroxysteroid Dehydrogenases - metabolism | Hydroxysteroid Dehydrogenases - metabolism | Retinaldehyde - physiology | Hydroxyprostaglandin Dehydrogenases - chemistry | Binding Sites | Mutagenesis, Site-Directed | Oxidoreductases - metabolism | Models, Molecular | Receptors, Retinoic Acid - antagonists & inhibitors | Receptors, Retinoic Acid - metabolism | 20-Hydroxysteroid Dehydrogenases - metabolism | Hydroxyprostaglandin Dehydrogenases - genetics | Aldo-Keto Reductase Family 1 Member C3 | Vitamin A - physiology | Retinaldehyde - pharmacology | Cell Line, Tumor | Protein Binding | 3-Hydroxysteroid Dehydrogenases - chemistry | Kinetics | 3-Hydroxysteroid Dehydrogenases - genetics | Amino Acid Substitution | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 510, Issue 7506, pp. 542 - 546
Journal Article
Biochemical Journal, ISSN 0264-6021, 07/2011, Volume 437, Issue 1, pp. 53 - 61
Journal Article