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Current Drug Targets, ISSN 1389-4501, 2013, Volume 14, Issue 13, pp. 1533 - 1541
Osteoporosis is posing a tremendous healthcare problem globally. Much effort has been invested in finding novel antiosteoporotic agents to stop the progression... 
Osteoblast | Osteoporosis | Osteoclast | Bone remodeling | Tocotrienol | VITAMIN-E | OXIDATIVE STRESS | OSTEOBLAST DIFFERENTIATION | DELTA-TOCOTRIENOL | COA REDUCTASE-ACTIVITY | osteoblast | osteoporosis | tocotrienol | GAMMA-TOCOTRIENOL | RECEPTOR ACTIVATOR | PHARMACOLOGY & PHARMACY | osteoclast | NF-KAPPA-B | NORMAL-MALE RATS | OSTEOCLAST DIFFERENTIATION
Journal Article
Journal Article
Cancer Immunology, Immunotherapy, ISSN 0340-7004, 8/2008, Volume 57, Issue 8, pp. 1241 - 1251
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 05/2010, Volume 30, Issue 5, pp. 894 - 899
Several decades ago, fibrates were approved for the treatment of dyslipidemia, whereas thiazolidinediones were screened in animal models to improve glucose... 
Pharmacology | Lipid metabolism | Nuclear receptors | Glucose homeostasis | Atherosclerosis | atherosclerosis | ACID | ETHYL CHLOROPHENOXYISOBUTYRATE | lipid metabolism | ALPHA | ANTI-HYPERLIPIDEMIC AGENTS | RANDOMIZED CONTROLLED-TRIAL | AGONISTS | nuclear receptors | glucose homeostasis | ANTIDIABETIC AGENTS | PPAR-DELTA | pharmacology | PERIPHERAL VASCULAR DISEASE | EXPERIMENTALLY ALTERED CELLS | ACYL-COA OXIDASE | HEMATOLOGY | Hypoglycemic Agents - therapeutic use | Peroxisome Proliferator-Activated Receptors - agonists | Dyslipidemias - drug therapy | Drug Discovery - history | Hypolipidemic Agents - history | History, 21st Century | Thiazolidinediones - history | History, 20th Century | Humans | Treatment Outcome | Diabetes Mellitus, Type 2 - history | Blood Glucose - drug effects | Thiazolidinediones - therapeutic use | Animals | Clofibric Acid - history | Clofibric Acid - therapeutic use | Lipid Metabolism - drug effects | Peroxisome Proliferator-Activated Receptors - history | Dyslipidemias - history | Hypolipidemic Agents - therapeutic use | Hypoglycemic Agents - history | Diabetes Mellitus, Type 2 - drug therapy | Life Sciences | Biochemistry, Molecular Biology | Antilipemic Agents | drug therapy | Dyslipidemias | Blood Glucose | drug effects | Lipid Metabolism | history | Drug Discovery | Hypoglycemic Agents | agonists | Peroxisome Proliferator-Activated Receptors | Clofibric Acid | Diabetes Mellitus, Type 2 | therapeutic use | Thiazolidinediones
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, p. e72331
Journal Article
British Journal of Haematology, ISSN 0007-1048, 01/2019, Volume 184, Issue 1, pp. 105 - 112
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 01/2018, Volume 24, Issue 1, pp. 120 - 129
Journal Article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, ISSN 1433-7851, 09/2014, Volume 53, Issue 39, pp. 10443 - 10447
A catalytic asymmetric total synthesis of the potent and selective antileukemic Delta(12)-prostaglandin J(3) (Delta(12)-PGJ(3)) is described. The convergent... 
leukemia | ACID | ANALOGS | DELTA-PGJ | METHYL | ALLYLIC OXIDATION | ALDEHYDES | asymmetric catalysis | 15-DEOXY-DELTA(12,14)-PGJ | CHEMISTRY, MULTIDISCIPLINARY | natural products | C-H activation | PROSTAGLANDINS | total synthesis | LIGAND | ADDITIONS
Journal Article
Prostaglandins, Leukotrienes and Essential Fatty Acids, ISSN 0952-3278, 08/2019, Volume 147, pp. 6 - 14
We previously discovered that palmitic acid methyl ester (PAME) is a potent vasodilator first identified and released from the superior cervical ganglion and... 
Hypoperfusion | Neuroprotection | Global ischemia | Cerebral blood flow | Palmitic acid methyl ester | Cardiac arrest | PROTEIN-KINASE-C | RISK-FACTORS | RAT | DELTA | BIOCHEMISTRY & MOLECULAR BIOLOGY | ISCHEMIA | MECHANISMS | CELL BIOLOGY | CA1 | ENDOCRINOLOGY & METABOLISM | CEREBRAL-BLOOD-FLOW | BRAIN | RESUSCITATION | Index Medicus
Journal Article
Translational psychiatry, ISSN 2158-3188, 2014, Volume 4, Issue 7, pp. e411 - e411
Current pharmacological treatments of depression and related disorders suffer from major problems, such as a low rate of response, slow onset of therapeutic... 
Animals | Humans | HEK293 Cells | Rats | Antidepressive Agents - pharmacology | Thiazepines - pharmacology | Receptors, Opioid, mu - agonists | Drug Evaluation, Preclinical | Receptors, Opioid, delta - agonists | Original
Journal Article
RSC ADVANCES, ISSN 2046-2069, 2019, Volume 9, Issue 13, pp. 7420 - 7431
In this study, bis(benzoyloxy)dimethylsilane (SDE) was developed as a non-phthalate selectivity control agent (internal donor (ID) and external donor (ED)) in... 
TITANIUM TETRACHLORIDE | POLYPROPYLENE | 110 SURFACES | INTERNAL ELECTRON-DONORS | DELTA-MGCL2 | ACTIVE-CENTER | PROPENE | MOLECULAR-WEIGHT DISTRIBUTION | EXTERNAL DONORS | CHEMISTRY, MULTIDISCIPLINARY | ETHYL BENZOATE
Journal Article
European Urology, ISSN 0302-2838, 2014, Volume 67, Issue 3, pp. 482 - 491
Abstract Background Patients with high-risk localised prostate cancer (PCa) are at risk of developing bone metastases (BMs). Zoledronic acid (ZA) significantly... 
Urology | Androgen deprivation therapy | Zoledronic acid | Anticancer agents | Bisphosphonates | Prostate cancer | Skeletal-related events | Bone metastases | DELTA T-CELLS | PHASE-3 | OSTEONECROSIS | THERAPY | MEN | UROLOGY & NEPHROLOGY | PLACEBO-CONTROLLED TRIAL | Multivariate Analysis | Humans | Middle Aged | Bone Neoplasms - secondary | Imidazoles - administration & dosage | Male | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Neoplasm Grading | Time Factors | Antineoplastic Agents - adverse effects | Treatment Failure | Aged, 80 and over | Diphosphonates - therapeutic use | Prostatic Neoplasms - blood | Adult | Kallikreins - blood | Imidazoles - therapeutic use | Diphosphonates - adverse effects | Prostatic Neoplasms - drug therapy | Prostatic Neoplasms - pathology | Bone Density Conservation Agents - adverse effects | Drug Administration Schedule | Europe | Imidazoles - adverse effects | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Bone Density Conservation Agents - therapeutic use | Diphosphonates - administration & dosage | Lymphatic Metastasis | Bone Density Conservation Agents - administration & dosage | Chi-Square Distribution | Prostate-Specific Antigen - blood | Administration, Intravenous | Bone Neoplasms - prevention & control | Aged | Care and treatment | Metastasis | Research | Health aspects | Oncology, Experimental | Cancer
Journal Article