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Nature neuroscience, ISSN 1097-6256, 08/2016, Volume 19, Issue 8, pp. 995 - 998
Myelin is synthesized as a multilamellar membrane, but the mechanisms of membrane turnover are unknown. We found that myelin pieces were gradually released... 
DYNAMICS | CELLS | NERVE-FIBERS | MICE | NEUROSCIENCES | DELETION | Brain - metabolism | Microglia - metabolism | Animals | Mice, Inbred C57BL | Mice, Transgenic | Demyelinating Diseases - chemically induced | Demyelinating Diseases - metabolism | Lipofuscin - metabolism | Aging - metabolism | Myelin Sheath - metabolism | Aging | Research | Analysis | Myelin proteins
Journal Article
Brain, ISSN 0006-8950, 2013, Volume 136, Issue 1, pp. 147 - 167
Journal Article
Neuroscience, ISSN 0306-4522, 2017, Volume 346, pp. 409 - 422
Journal Article
Nature Reviews Neurology, ISSN 1759-4758, 03/2011, Volume 7, Issue 3, pp. 165 - 172
Several neurological disorders have been associated with the use of monoclonal antibodies (mAbs), especially those targeting tumor necrosis factor (TNF) and... 
RHEUMATOID-ARTHRITIS | PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY | MULTIPLE-SCLEROSIS | ADALIMUMAB | DISEASE | GLOBAL CLINICAL-TRIALS | PERIPHERAL NEUROPATHY | NECROSIS-FACTOR-ALPHA | TNF-TARGETED THERAPIES | INFLIXIMAB THERAPY | CLINICAL NEUROLOGY | Leukoencephalopathy, Progressive Multifocal - immunology | Peripheral Nervous System Diseases - chemically induced | Leukoencephalopathy, Progressive Multifocal - prevention & control | Humans | Antibodies, Monoclonal - adverse effects | Autoimmune Diseases - complications | Antibodies, Monoclonal - therapeutic use | Demyelinating Diseases - prevention & control | Leukoencephalopathy, Progressive Multifocal - chemically induced | Nervous System Diseases - prevention & control | Peripheral Nervous System Diseases - prevention & control | Demyelinating Diseases - immunology | Tumor Necrosis Factor-alpha - immunology | Product Surveillance, Postmarketing | Nervous System Diseases - chemically induced | Demyelinating Diseases - chemically induced | Autoimmune Diseases - chemically induced | Nervous System Diseases - immunology | Peripheral Nervous System Diseases - immunology | Autoimmune Diseases - drug therapy | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Nervous system diseases | Care and treatment | Tumor necrosis factor | Monoclonal antibodies | Physiological aspects | Research | Health aspects
Journal Article
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 9/2012, Volume 124, Issue 3, pp. 411 - 424
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 2014, Volume 34, Issue 24, pp. 8186 - 8196
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2015, Volume 125, Issue 5, pp. 2161 - 2170
Microglia contribute to development, homeostasis, and immunity of the CNS. Like other tissue-resident macrophage populations, microglia express the surface... 
MEDICINE, RESEARCH & EXPERIMENTAL | CNS REMYELINATION | ALZHEIMERS-DISEASE | MACROPHAGES | SCLEROSING LEUKOENCEPHALOPATHY | MOUSE MODEL | RECEPTOR | CENTRAL-NERVOUS-SYSTEM | BETA-CATENIN | MYELOID CELLS-2 | CUTTING EDGE | Receptors, Immunologic - physiology | Cell Count | Humans | Nerve Tissue Proteins - deficiency | Gene Expression Profiling | Phagocytosis - genetics | Myelin Sheath - metabolism | Membrane Glycoproteins - physiology | Microglia - immunology | Osteochondrodysplasias - genetics | Nerve Tissue Proteins - biosynthesis | Microglia - pathology | Transcription, Genetic | Demyelinating Diseases - chemically induced | Demyelinating Diseases - pathology | Genes, Reporter | Disease Models, Animal | Cuprizone - toxicity | Myelin Sheath - physiology | Nerve Tissue Proteins - physiology | Receptors, Immunologic - deficiency | Nerve Tissue Proteins - genetics | Membrane Glycoproteins - genetics | Mice, Knockout | Lipodystrophy - genetics | Regeneration | Animals | Axons - pathology | Subacute Sclerosing Panencephalitis - genetics | Brain - pathology | Mice | Receptors, Immunologic - genetics | Membrane Glycoproteins - deficiency | Aging - metabolism | Physiological aspects | Development and progression | Cell receptors | Research | Demyelinating diseases | Phosphorylation | Statistical analysis | Lipids | Data processing | Genomes | Kinases | Gene expression | Brain research | Blood-brain barrier | Rodents | Morphology | Aging | Alzheimers disease | Expansion | Apoptosis
Journal Article