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Journal Article
Journal of Controlled Release, ISSN 0168-3659, 06/2014, Volume 183, Issue 1, pp. 18 - 26
Direct administration of chemotherapeutic drugs to the lungs significantly enhances drug exposure to lung resident cancers and may improve chemotherapy when... 
Lung metastases | Dendrimer | Pharmacokinetics | Pulmonary | Inhalation | DELIVERY SYSTEMS | SAFETY | PENETRATION | TOXICITY | TUMORS | CHEMISTRY, MULTIDISCIPLINARY | TRANSPORT | LYMPHATIC EXPOSURE | SOLUTION FORMULATIONS | PHARMACOLOGY & PHARMACY | PHASE-I | Doxorubicin - therapeutic use | Lung Neoplasms - drug therapy | Injections, Intravenous | Dendrimers - therapeutic use | Lung Neoplasms - metabolism | Rats, Inbred F344 | Male | Mammary Neoplasms, Experimental - metabolism | Drug Delivery Systems | Tissue Distribution | Lung Neoplasms - secondary | Doxorubicin - analogs & derivatives | Mammary Neoplasms, Experimental - pathology | Female | Lung - metabolism | Molecular Structure | Antibiotics, Antineoplastic - pharmacokinetics | Doxorubicin - administration & dosage | Mammary Neoplasms, Experimental - drug therapy | Lung - pathology | Dendrimers - pharmacokinetics | Administration, Inhalation | Rats, Sprague-Dawley | Doxorubicin - pharmacokinetics | Antibiotics, Antineoplastic - administration & dosage | Animals | Antibiotics, Antineoplastic - therapeutic use | Lung - drug effects | Drug Liberation | Dendrimers - administration & dosage | Delayed-Action Preparations | Biodegradation | Drugs | Dendrimers | Anthracyclines | Drug delivery systems | Chemotherapy | Analysis | Dosage and administration | Metastasis | Health aspects | Vehicles | Cancer | Index Medicus
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 03/2016, Volume 501, Issue 1-2, pp. 271 - 277
Journal Article
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 07/2015, Volume 210, pp. 160 - 168
Journal Article
Molecular Therapy, ISSN 1525-0016, 12/2011, Volume 19, Issue 12, pp. 2228 - 2238
We evaluated the efficacy of structurally flexible, cationic PAMAM dendrimers as a small interfering RNA (siRNA) delivery system in a Rag2 / γc / (RAG-hu)... 
MEDICINE, RESEARCH & EXPERIMENTAL | DOUBLE-STRANDED-RNA | PAMAM DENDRIMERS | PRIMARY-CELLS | SIRNA DELIVERY | CLEAVAGE | POTENT | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PROGRESS | DISEASE | GENETICS & HEREDITY | INTERFERENCE | THERAPIES | HIV Infections - prevention & control | Leukocytes, Mononuclear - metabolism | RNA, Small Interfering - genetics | Humans | rev Gene Products, Human Immunodeficiency Virus - metabolism | Leukocytes, Mononuclear - virology | Viral Load | T-Lymphocytes, Helper-Inducer - virology | CD4-Positive T-Lymphocytes - immunology | Dendrimers | Flow Cytometry | HIV-1 - physiology | RNA, Viral - genetics | T-Lymphocytes, Helper-Inducer - immunology | tat Gene Products, Human Immunodeficiency Virus - antagonists & inhibitors | CD4-Positive T-Lymphocytes - virology | DEAD-box RNA Helicases - metabolism | Interleukin Receptor Common gamma Subunit - physiology | Disease Models, Animal | DNA-Binding Proteins - physiology | Ribonuclease III - metabolism | tat Gene Products, Human Immunodeficiency Virus - genetics | HIV Infections - genetics | HIV Infections - virology | Liver - metabolism | Viremia - genetics | Mice, Knockout | Animals | Viremia - virology | Viremia - prevention & control | Leukocytes, Mononuclear - cytology | Liver - cytology | Mice | Mice, Inbred BALB C | Nanoparticles - administration & dosage | rev Gene Products, Human Immunodeficiency Virus - genetics | rev Gene Products, Human Immunodeficiency Virus - antagonists & inhibitors | RNA, Small Interfering - administration & dosage | tat Gene Products, Human Immunodeficiency Virus - metabolism | Original
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 2011, Volume 79, Issue 2, pp. 232 - 240
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 03/2017, Volume 249, pp. 173 - 182
Journal Article