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Immunity, ISSN 1074-7613, 03/2013, Volume 38, Issue 3, pp. 514 - 527
Interleukin-21 (IL-21) has broad actions on T and B cells, but its actions in innate immunity are poorly understood. Here we show that IL-21 induced apoptosis... 
NKT CELLS | HOMEOSTASIS | FOLLICULAR-HELPER-CELLS | HUMAN B-CELLS | STEADY-STATE | INTERLEUKIN-21 | DIFFERENTIATION | IMMUNOLOGY | IMMUNE TOLERANCE | T-CELLS | NEGATIVE REGULATOR | Natural Killer T-Cells - drug effects | Oligonucleotide Array Sequence Analysis | Apoptosis - drug effects | Dendritic Cells - immunology | STAT5 Transcription Factor - immunology | Receptors, Interleukin-21 - genetics | Interferon-gamma - metabolism | CD4-Positive T-Lymphocytes - immunology | Interleukins - genetics | Gene Expression - immunology | STAT3 Transcription Factor - genetics | Apoptosis Regulatory Proteins - immunology | DNA-Binding Proteins - immunology | Membrane Proteins - genetics | CD4-Positive T-Lymphocytes - metabolism | Mice, Transgenic | DNA, Intergenic - genetics | Protein Binding - immunology | Blotting, Western | Apoptosis Regulatory Proteins - metabolism | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Mice, Knockout | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Galactosylceramides - immunology | Mice | STAT3 Transcription Factor - immunology | Gene Expression - drug effects | Galactosylceramides - pharmacology | DNA-Binding Proteins - deficiency | STAT5 Transcription Factor - genetics | STAT5 Transcription Factor - metabolism | Receptors, Interleukin-21 - deficiency | Flow Cytometry | Bcl-2-Like Protein 11 | Natural Killer T-Cells - metabolism | DNA, Intergenic - metabolism | Interleukins - immunology | Proto-Oncogene Proteins - immunology | Apoptosis Regulatory Proteins - genetics | Dendritic Cells - drug effects | Membrane Proteins - metabolism | Interleukins - pharmacology | Dendritic Cells - metabolism | STAT3 Transcription Factor - metabolism | Proto-Oncogene Proteins - metabolism | Receptors, Interleukin-21 - immunology | Mice, Inbred C57BL | Cells, Cultured | Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology | Membrane Proteins - immunology | Proto-Oncogene Proteins - genetics | DNA-Binding Proteins - genetics | Animals | Apoptosis - immunology | Interferon-gamma - immunology | CD4-Positive T-Lymphocytes - drug effects | DNA, Intergenic - immunology | Natural Killer T-Cells - immunology | Interleukins | Dendritic cells | Analysis | Genomics | Macrophage colony stimulating factor | Biological response modifiers | T cells | Apoptosis | Cytokines | Genes | Genomes | Kinases | Binding sites | Deoxyribonucleic acid--DNA | Index Medicus | apoptosis | dendritic cells | GM-CSF | IL-21
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 10/2009, Volume 183, Issue 8, pp. 5418 - 5427
IFN-beta-1a has been used over the past 15 years as a primary therapy for relapsing-remitting multiple sclerosis (MS). However, the immunomodulatory mechanisms... 
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | GROWTH-FACTOR-BETA | T(H)17 CELLS | MULTIPLE-SCLEROSIS | DENDRITIC CELLS | MESSENGER-RNA EXPRESSION | CENTRAL-NERVOUS-SYSTEM | INTERFERON-BETA | IMMUNOLOGY | UP-REGULATION | T-CELLS | Receptors, CCR6 - immunology | Interleukin-12 Subunit p35 - metabolism | Interleukin-23 Subunit p19 - antagonists & inhibitors | Dendritic Cells - immunology | Humans | Receptors, CCR6 - antagonists & inhibitors | CD4-Positive T-Lymphocytes - immunology | Receptors, Interleukin - metabolism | Interleukin-23 Subunit p19 - metabolism | STAT1 Transcription Factor - metabolism | Interleukin-1beta - metabolism | Receptors, Retinoic Acid - immunology | Phosphorylation - immunology | Phosphorylation - drug effects | Receptors, Thyroid Hormone - immunology | Interleukin-1beta - antagonists & inhibitors | Nuclear Receptor Subfamily 1, Group F, Member 3 | Receptors, Interleukin - immunology | Receptors, Interleukin - antagonists & inhibitors | Receptors, Retinoic Acid - metabolism | Cell Differentiation - immunology | Interferon beta-1a | Up-Regulation - immunology | Interleukin-23 Subunit p19 - immunology | STAT3 Transcription Factor - immunology | Interleukin-10 - immunology | Interleukin-17 - immunology | STAT1 Transcription Factor - drug effects | T-Lymphocytes, Helper-Inducer - drug effects | T-Lymphocytes, Helper-Inducer - immunology | Receptors, CCR6 - metabolism | Interleukin-10 - metabolism | Dendritic Cells - drug effects | Interleukin-10 - agonists | STAT3 Transcription Factor - metabolism | Cells, Cultured | Interleukin-1beta - immunology | Interleukin-12 Subunit p35 - agonists | Down-Regulation - drug effects | STAT1 Transcription Factor - immunology | Receptors, Thyroid Hormone - metabolism | Up-Regulation - drug effects | Interferon-beta - pharmacology | Interleukin-12 Subunit p35 - immunology | Cell Differentiation - drug effects | Down-Regulation - immunology | STAT3 Transcription Factor - drug effects | Multiple Sclerosis - immunology | CD4-Positive T-Lymphocytes - drug effects | Index Medicus | Abridged Index Medicus
Journal Article
Nature Immunology, ISSN 1529-2908, 07/2015, Volume 16, Issue 8, pp. 871 - 879
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Nature Immunology, ISSN 1529-2908, 11/2012, Volume 13, Issue 11, pp. 1118 - 1128
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2013, Volume 110, Issue 44, pp. 17945 - 17950
Journal Article