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1. Changing concepts in caries microbiology
by Russell, Roy R
American Journal of Dentistry, ISSN 0894-8275, 10/2009, Volume 22, Issue 5, pp. 304 - 310
Concepts and beliefs about the cause of dental caries have evolved over many centuries, with the involvement of microorganisms being recognized since the late... 
STREPTOCOCCUS-MUTANS | SELECTIVE MEDIUM | GTF GENES | ROOT CARIES | ORAL STREPTOCOCCI | DENTISTRY, ORAL SURGERY & MEDICINE | DENTAL-CARIES | PLAQUE HYPOTHESIS | EARLY-CHILDHOOD CARIES | YOUNG-CHILDREN | MOLECULAR ANALYSIS | Lactobacillus - classification | Streptococcus mutans - pathogenicity | Animals | Dental Caries - microbiology | Molecular Biology | Bifidobacterium - classification | Humans | Virulence | Bacteriological Techniques | Colony Count, Microbial | Streptococcus mutans - classification
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2. Full Text The Role of Bacteria in the Caries Process
: Ecological Perspectives
by Takahashi, N and Nyvad, B
Journal of Dental Research, ISSN 0022-0345, 3/2011, Volume 90, Issue 3, pp. 294 - 303
Dental biofilms produce acids from carbohydrates that result in caries. According to the extended caries ecological hypothesis, the caries process consists of... 
extended caries ecological hypothesis | Bifidobacterium | mutans streptococci | caries-associated bacteria | acid-induced selection | Actinomyces | acidurance | acid-induced adaptation | acidogenicity | non-mutans streptococci | caries process | Lactobacillus | ROOT-SURFACE CARIES | LOW-PH | ORAL MICROBIAL COMMUNITIES | DENTAL-CARIES | EARLY-CHILDHOOD CARIES | VIRIDANS GROUP STREPTOCOCCI | MOLECULAR ANALYSIS | ACTINOMYCES-NAESLUNDII | DENTISTRY, ORAL SURGERY & MEDICINE | ACID PRODUCTION | Dental Caries - microbiology | Humans | Lactobacillus - metabolism | Host-Pathogen Interactions | Dental Plaque - microbiology | Animals | Biofilms | Actinomyces - metabolism | Ecosystem | Bifidobacterium - metabolism | Glycolysis | Streptococcus - metabolism | Hydrogen-Ion Concentration
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3. Full Text How Has Genomics Altered Our View of Caries Microbiology?
by Russell, R.R.B
Caries Research, ISSN 0008-6568, 09/2008, Volume 42, Issue 5, pp. 319 - 327
Genome sequencing and other molecular techniques for the identification and characterisation of bacteria have provided us with a vast amount of new... 
Current Topic | Cariogenic microflora | Genome sequencing | Genomics | Streptococcus mutans | LACTIC-ACID | PHENOTYPIC CHARACTERIZATION | ORAL STREPTOCOCCI | STRESS-RESPONSIVE PROTEINS | STREPTOCOCCUS-MUTANS BIOFILMS | DENTAL-CARIES | MOLECULAR ANALYSIS | CHILDHOOD CARIES | GLUCAN-BINDING | DENTISTRY, ORAL SURGERY & MEDICINE | GENE-EXPRESSION | Dental Plaque - microbiology | Genome, Bacterial - genetics | Gene Expression Regulation, Bacterial - genetics | Dental Caries - microbiology | Humans | Streptococcus mutans - genetics | Genomics - methods
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4. Full Text Solving the etiology of dental caries
by Simón-Soro, Aurea and Mira, Alex
Trends in Microbiology, ISSN 0966-842X, 2014, Volume 23, Issue 2, pp. 76 - 82
Highlights • Dental caries is a polymicrobial disease caused by various consortia. • Caries is caused by pathobionts present at low levels under healthy... 
Internal Medicine | tooth decay | pathobiont | Koch's postulates | metatranscriptomics | dysbiosis | Tooth decay | Metatranscriptomics | Dysbiosis | Pathobiont | STREPTOCOCCUS-MUTANS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ORAL-HEALTH | MICROBIOLOGY | MICROBIOTA | COLONIZATION | CHILDREN | DISRUPTION | DYNAMICS | DIVERSITY | ASSOCIATION | Dental Caries - genetics | Anti-Bacterial Agents - therapeutic use | Coinfection - microbiology | Microbial Consortia - physiology | Dental Caries - microbiology | Streptococcus mutans - physiology | Coinfection - drug therapy | Humans | Streptococcus mutans - isolation & purification | Transcriptome | Dental Caries - prevention & control | Dental caries | Development and progression | Causes and theories of causation | Diseases
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5. Full Text Caries Ecology Revisited: Microbial Dynamics and the Caries Process
by Takahashi, N and Nyvad, B
Caries Research, ISSN 0008-6568, 11/2008, Volume 42, Issue 6, pp. 409 - 418
In this essay we propose an extension of the caries ecological hypothesis to explain the relation between dynamic changes in the phenotypic/genotypic... 
Current Topic | Dental caries | Mutans streptococci | Non-mutans streptococci | Actinomyces | Dental plaque | Ecology | Dental biofilm | Non-mutans bacteria | LOW-PH | LESION ACTIVITY | IODOPHILIC POLYSACCHARIDE | ORAL STREPTOCOCCI | HUMAN DENTAL PLAQUE | MOLECULAR ANALYSIS | CARIOUS HUMAN ROOT | ACTINOMYCES-NAESLUNDII | DENTISTRY, ORAL SURGERY & MEDICINE | TOOTH SURFACES | Dental Plaque - microbiology | Phenotype | Biofilms | Dental Caries - microbiology | Ecosystem | Humans | Bacterial Physiological Phenomena | Genotype | Bacteria - genetics
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6. Full Text Microbiology of Dental Plaque Biofilms and Their Role in Oral Health and Caries
by Marsh, Philip D., PhD
Dental Clinics of North America, ISSN 0011-8532, 2010, Volume 54, Issue 3, pp. 441 - 454
Dental plaque is the biofilm found naturally on teeth. Dental plaque is also implicated in dental caries, which is associated with shifts in the microbial... 
Dentistry | Dental plaque | Biofilm | Dental caries | Ecology | Interventions | Dental Plaque - microbiology | Dental Caries - pathology | Dental Caries - microbiology | Mouth - microbiology | Humans | Bacteria - classification | Oral Health | Biofilms - classification | Microbial Interactions
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7. Full Text Role of microbial biofilms in the maintenance of oral health and in the development of dental caries and periodontal diseases. Consensus report of group 1 of the Joint EFP/ORCA workshop on the boundaries between caries and periodontal disease
by Sanz, Mariano and Beighton, David and Curtis, Michael A and Cury, Jaime A and Dige, Irene and Dommisch, Henrik and Ellwood, Roger and Giacaman, Rodrigo and Herrera, David and Herzberg, Mark C and Könönen, Eija and Marsh, Philip D and Meyle, Joerg and Mira, Alex and Molina, Ana and Mombelli, Andrea and Quirynen, Marc and Reynolds, Eric C and Shapira, Lior and Zaura, Egija
Journal of Clinical Periodontology, ISSN 0303-6979, 03/2017, Volume 44, Issue S18, pp. S5 - S11
Background and Aims: The scope of this working group was to review (1) ecological interactions at the dental biofilm in health and disease, (2) the role of... 
dental biofilm | innate host responses | symbiosis | microbial interactions | periodontal diseases | caries | dysbiosis | DENTISTRY, ORAL SURGERY & MEDICINE | ANTIMICROBIAL PEPTIDES | Host-Pathogen Interactions | Biofilms | Dental Caries - microbiology | Oral Health | Periodontitis - microbiology | Humans | Dental caries | Periodontal disease | Conferences, meetings and seminars | Fermentation | Workshops (Educational programs) | Organic acids | Dentin | Mucosa | Innate immunity | Gingivitis | Periodontal diseases | Microorganisms | Dental enamel | Periodontitis | Proteolysis | Oral hygiene | Gingiva | Saliva
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8. Full Text The oral microbiome and the immunobiology of periodontal disease and caries
by Costalonga, Massimo and Herzberg, Mark C
Immunology Letters, ISSN 0165-2478, 2014, Volume 162, Issue 2, pp. 22 - 38
Highlights • The core oral microbiome and in various ecological niches. • Microbial ecology of the tooth crown and the gingival sulcus. • Sustained high... 
Allergy and Immunology | Caries | Periodontitis | Pathogenesis | Microbiome | STREPTOCOCCUS-MUTANS | AGGRESSIVE PERIODONTITIS | PORPHYROMONAS-GINGIVALIS | SALIVARY IMMUNOGLOBULIN-A | GINGIVAL CREVICULAR FLUID | CD4(+) T-CELLS | DENTAL-CARIES | IMMUNOLOGY | HOST RESPONSE | ALVEOLAR BONE LOSS | PYROSEQUENCING ANALYSIS | Gingiva - immunology | Dental Caries - microbiology | Microbiota - immunology | Humans | Immunity, Mucosal | Mouth - immunology | Periodontal Diseases - microbiology | Immunoglobulin A, Secretory - immunology | Dysbiosis - microbiology | Dysbiosis - immunology | Streptococcus mutans - immunology | Dental Caries - immunology | Animals | Mouth - microbiology | Porphyromonas gingivalis - immunology | Periodontal Diseases - immunology | Niche (Ecology)
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9. Full Text Hypoplasia-associated Severe Early Childhood Caries – A Proposed Definition
by Caufield, P.W and Li, Y and Bromage, T.G
Journal of Dental Research, ISSN 0022-0345, 6/2012, Volume 91, Issue 6, pp. 544 - 550
We propose a new classification of severe early childhood caries (S-ECC): hypoplasia-associated severe early childhood caries (HAS-ECC). This form of caries... 
tooth development | odontogenesis | access to care | pediatric dentistry | caries | Streptococcus mutans | STREPTOCOCCUS-MUTANS | PRIMARY DENTITION | ENAMEL HYPOPLASIA | DEFECTS | PRIMARY TEETH | LINEAR HYPOPLASIA | PRETERM INFANTS | CHINESE CHILDREN | DENTISTRY, ORAL SURGERY & MEDICINE | SOCIOECONOMIC-STATUS | DENTAL HARD TISSUES | DMF Index | Minority Groups | Dental Caries Susceptibility | Prenatal Exposure Delayed Effects | Amelogenesis | Dental Caries - microbiology | Diet, Cariogenic | Poverty | Dental Caries - etiology | Humans | Risk Factors | Child, Preschool | Terminology as Topic | Dental Enamel Hypoplasia - complications | Bottle Feeding - adverse effects | Pregnancy | Dental Enamel Hypoplasia - embryology | Streptococcus mutans - physiology | Female | Tooth, Deciduous | Dental Caries - classification | Reviews
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10. Full Text Saliva microbiomes distinguish caries-active from healthy human populations
by Yang, Fang and Zeng, Xiaowei and Ning, Kang and Liu, Kuan-Liang and Lo, Chien-Chi and Wang, Wei and Chen, Jie and Wang, Dongmei and Huang, Ranran and Chang, Xingzhi and Chain, Patrick S and Xie, Gary and Ling, Junqi and Xu, Jian
ISME Journal, ISSN 1751-7362, 01/2012, Volume 6, Issue 1, pp. 1 - 10
The etiology of dental caries remains elusive because of our limited understanding of the complex oral microbiomes. The current methodologies have been limited... 
saliva | oral-microbiome | Prevotella | metagenomics | caries | SYSTEM | HUMAN-BODY | BACTERIA | DENTAL-CARIES | MICROBIOLOGY | ORAL MICROFLORA | CHILDREN | CHILDHOOD CARIES | DISEASES | COMMUNITY | ECOLOGY | DIVERSITY | Dental Caries - microbiology | Humans | Phylogeny | Young Adult | Animals | Mouth - microbiology | China | Adolescent | RNA, Ribosomal, 16S - genetics | Saliva - microbiology | Prevotella - genetics | Prevotella - isolation & purification | Metagenome | Community structure | Dental caries | Prognosis | rRNA 16S | Etiology | Abundance | Data processing | Sampling | Saliva | Population levels | Original
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11. Full Text Dental Caries from a Molecular Microbiological Perspective
by Nyvad, B and Crielaard, W and Mira, A and Takahashi, N and Beighton, D
Caries Research, ISSN 0008-6568, 02/2013, Volume 47, Issue 2, pp. 89 - 102
Dental caries results from an imbalance of the metabolic activity in the dental biofilm. The microbial communities of teeth have traditionally been studied by... 
Review | 16S rRNA | Dental caries | Metabolomics | Metagenomics | Molecular microbiology | Next-generation sequencing | Metatranscriptomics | STREPTOCOCCUS-MUTANS | MICROCOSM BIOFILMS | ROOT CARIES | RIBOSOMAL-RNA GENES | PLAQUE | 165 rRNA | POLYMERASE-CHAIN-REACTION | ACTINOMYCES-NAESLUNDII | BACTERIAL DIVERSITY | DNA | DENTISTRY, ORAL SURGERY & MEDICINE | ORAL MICROBIOTA | Metagenome - genetics | Biofilms | Dental Caries - microbiology | Humans | RNA, Bacterial - genetics | RNA, Ribosomal, 16S - genetics | Transcriptome - genetics | Genetic Techniques | Metabolome - genetics
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