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Chemistry & Biodiversity, ISSN 1612-1872, 03/2019, Volume 16, Issue 3, pp. e1800497 - n/a
2‐Chloro‐2′‐deoxyadenosine (cladribine, 1 ) was acylated with valproic acid ( 2 ) under various reaction conditions yielding 2‐chloro‐2′‐deoxy‐3′,5′‐ O... 
glioblastoma | biological activity | cladribine | multiple sclerosis | drug profiling | nucleolipids | cancerostatic/cancerotoxic activity | Deoxyadenosines - chemistry | 2-Chloroadenosine - pharmacology | Antineoplastic Agents - chemical synthesis | Humans | 2-Chloroadenosine - analogs & derivatives | 2-Chloroadenosine - chemical synthesis | Structure-Activity Relationship | Valproic Acid - pharmacology | Dose-Response Relationship, Drug | 2-Chloroadenosine - chemistry | Antineoplastic Agents - pharmacology | Molecular Structure | Tumor Cells, Cultured | Valproic Acid - chemistry | Cell Survival - drug effects | Rats | Valproic Acid - chemical synthesis | Antineoplastic Agents - chemistry | Azauridine - chemical synthesis | Azauridine - chemistry | Animals | Hydrophobic and Hydrophilic Interactions | Azauridine - pharmacology | Cell Proliferation - drug effects | Deoxyadenosines - pharmacology | Deoxyadenosines - chemical synthesis | Drug Screening Assays, Antitumor | Divalproex | Multiple sclerosis | Gliomas | Analysis | Cladribine | Nuclear magnetic resonance spectroscopy | Valproic acid | Derivatives (Financial instruments) | Mass spectrometry | Drugs | Brain cancer | Mass spectroscopy | Derivatives | Macrophages | Crystallography | Deoxyadenosine | Oligodendroglioma | Anticancer properties | Magnetic resonance spectroscopy | Lipophilic | Acids | Dicyclohexylcarbodiimide | Antitumor activity | NMR spectroscopy | Acetic acid | Astrocytoma | Index Medicus
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