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by Meng, H and Wang, MY and Liu, HY and Liu, XS and Situ, A and Wu, B and Ji, ZX and Chang, CH and Nel, AE
ACS NANO, ISSN 1936-0851, 04/2015, Volume 9, Issue 4, pp. 3540 - 3557
Recently, a commercial albumin-bound paclitaxel (PTX) nanocarrier (Abraxane) was approved as the first new drug for pancreatic ductal adenocarcinoma in almost... 
SUPPORTED MEMBRANES | paclitaxel | PHYSICAL-PROPERTIES | synergy | mesoporous silica nanoparticle | VIVO | NAB-PACLITAXEL | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | MODEL | CYTIDINE DEAMINASE | CHEMISTRY, MULTIDISCIPLINARY | OVERCOME DRUG-RESISTANCE | co-delivery | pancreatic cancer | IN-VITRO | ratiometric | gemcitabine | BILAYERS PROTOCELLS | NANOTECHNOLOGY | Albumins - chemistry | Deoxycytidine - chemistry | Paclitaxel - pharmacology | Pancreatic Neoplasms - metabolism | Nanoparticles - chemistry | Humans | Deoxycytidine - pharmacology | Antineoplastic Agents - therapeutic use | Drug Carriers - chemistry | Pancreatic Neoplasms - drug therapy | Albumins - therapeutic use | Paclitaxel - chemistry | Deoxycytidine - therapeutic use | Female | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Pancreatic Neoplasms - pathology | Silicon Dioxide - chemistry | Antineoplastic Agents - chemistry | Paclitaxel - therapeutic use | Drug Synergism | Albumins - pharmacology | Animals | Cell Transformation, Neoplastic | Cytidine Deaminase - metabolism | Cell Line, Tumor | Mice | Lipid Bilayers - chemistry | Porosity | Deoxycytidine - analogs & derivatives | Index Medicus | Drugs | Effectiveness | Metabolites | Biocompatibility | Lipids | Nanostructure | Tumors | Cancer
Journal Article
ACS Nano, ISSN 1936-0851, 11/2013, Volume 7, Issue 11, pp. 10048 - 10065
Pancreatic ductal adenocarcinoma (PDAC) elicits a dense stromal response that blocks vascular access because of pericyte coverage of vascular fenestrations. In... 
mesoporous silica nanoparticles | pericyte and stroma | pancreatic cancer | two-wave | nano-engineered approach | TGF-β | gemcitabine | liposome | BREAST-CARCINOMA | DUCTAL ADENOCARCINOMA | NAB-PACLITAXEL | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | VIVO ANTITUMOR-ACTIVITY | CYTIDINE DEAMINASE | CHEMISTRY, MULTIDISCIPLINARY | TGF-beta | GROWTH-FACTOR-BETA | IN-VIVO | PROSTATE-CANCER | Neoplasm Transplantation | Deoxycytidine - chemistry | Nanoparticles - chemistry | Humans | Collagen - chemistry | Polyethylene Glycols - chemistry | Proteoglycans - chemistry | Drug Carriers | Pancreatic Neoplasms - drug therapy | Polyethyleneimine - chemistry | Transforming Growth Factor beta - antagonists & inhibitors | Female | Microscopy, Electron, Transmission | Signal Transduction | Deoxycytidine - administration & dosage | Silicon Dioxide - chemistry | Smad2 Protein - metabolism | Liposomes - chemistry | Animals | Endothelial Cells - cytology | Nanomedicine - methods | Cell Line, Tumor | Laminin - chemistry | Mice | Mice, Inbred BALB C | Deoxycytidine - analogs & derivatives | Drug Combinations | Index Medicus | Drugs | Drug delivery systems | Polyetherimides | Interference | Nitrogen atoms | Nanostructure | Liposomes | Tumors | Cancer | Nano engineered approach | and liposome
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 05/2016, Volume 229, pp. 183 - 191
Functional nanocarriers capable of transporting high drug contents without premature leakage and to controllably deliver several drugs are needed for better... 
Mesoporous silica nanoparticles | Multi-drug delivery | Bovine serum albumin | Gold nanoclusters | Cancer | BRIDGED SILSESQUIOXANE NANOPARTICLES | VITRO | PEGYLATED LIPOSOMAL DOXORUBICIN | COMBINATION | CHEMISTRY, MULTIDISCIPLINARY | GEMCITABINE | BREAST-CANCER | NANOCLUSTERS | RESPONSIVE CONTROLLED-RELEASE | FLUORESCENT-PROBES | PHARMACOLOGY & PHARMACY | ORGANOSILICA NANOPARTICLES | Silicon Dioxide - administration & dosage | Deoxycytidine - chemistry | Gold - administration & dosage | Nanocomposites - chemistry | Nanoparticles - chemistry | Serum Albumin, Bovine - administration & dosage | Humans | Drug Carriers - administration & dosage | Doxorubicin - chemistry | Antineoplastic Agents - administration & dosage | Drug Carriers - chemistry | Serum Albumin, Bovine - chemistry | Doxorubicin - administration & dosage | Gold - chemistry | A549 Cells | Cell Line | Deoxycytidine - administration & dosage | Silicon Dioxide - chemistry | Antineoplastic Agents - chemistry | Neoplasms - diagnostic imaging | Neoplasms - drug therapy | Drug Liberation | Nanoparticles - administration & dosage | Porosity | Deoxycytidine - analogs & derivatives | Nanocomposites - administration & dosage | Nanoparticles | Drugs | Albumin | Precious metal products | Silica | Tumors | Drug delivery systems | Anthracyclines | Pharmaceutical industry | Vehicles | Index Medicus
Journal Article
Chemical Biology & Drug Design, ISSN 1747-0277, 03/2017, Volume 89, Issue 3, pp. 379 - 399
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