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Cancer Cell, ISSN 1535-6108, 04/2016, Volume 29, Issue 4, pp. 548 - 562
Although glycolysis is substantially elevated in many tumors, therapeutic targeting of glycolysis in cancer patients has not yet been successful, potentially... 
NOVO PYRIMIDINE SYNTHESIS | MTORC1 | ONCOLOGY | PATHWAY | GROWTH | 2-DEOXY-D-GLUCOSE | PROLIFERATION | CARBOXYLATION | CONTRIBUTES | DEHYDROGENASE | GLUTAMINE-METABOLISM | CELL BIOLOGY | Neoplasms - metabolism | Metabolomics | Pentose Phosphate Pathway - drug effects | Glutaminase - physiology | Humans | Neoplasm Proteins - physiology | Ovarian Neoplasms - pathology | Glutamine - metabolism | Drug Resistance, Neoplasm | Neoplasm Proteins - antagonists & inhibitors | Ribosomal Protein S6 Kinases, 70-kDa - physiology | Adenosine Triphosphate - biosynthesis | Molecular Targeted Therapy | Glycolysis - drug effects | Glucose-6-Phosphate Isomerase - genetics | Mechanistic Target of Rapamycin Complex 1 | Multiprotein Complexes - antagonists & inhibitors | Deoxyglucose - therapeutic use | TOR Serine-Threonine Kinases - antagonists & inhibitors | RNA Interference | Deoxyglucose - pharmacology | Everolimus - therapeutic use | Female | TOR Serine-Threonine Kinases - physiology | Carcinoma - pathology | Cytokines - genetics | Tumor Stem Cell Assay | Pentose Phosphate Pathway - physiology | Everolimus - pharmacology | Ribosomal Protein S6 Kinases, 70-kDa - antagonists & inhibitors | Combined Modality Therapy | Glutaminase - antagonists & inhibitors | Citric Acid Cycle | Hep G2 Cells | Multiprotein Complexes - physiology | Neoplasms - drug therapy | Drug Synergism | Xenograft Model Antitumor Assays | Animals | Mice, Nude | RNA, Small Interfering - therapeutic use | Glucose-6-Phosphate Isomerase - antagonists & inhibitors | Cell Line, Tumor | Mice | Cytokines - antagonists & inhibitors | Energy Metabolism - drug effects | Phosphates | Glucose metabolism | Cancer cells | Glucose | Molecular biology | Dextrose | Cancer
Journal Article
Food Chemistry, ISSN 0308-8146, 02/2017, Volume 217, pp. 602 - 609
The antiglycative activity of hydroxytyrosol (HT) and olive leaf extract (OLE) was investigated in wheat-flour biscuits. Quercetin (QE) and gallic acid (GA)... 
Hydroxytyrosol | 1,2-dicarbonyl compounds | Olive leaf | Antiglycative activity | Hydroxymethylfurfural | Maillard reaction | Dietary advanced glycation endproducts | COOKIES | PHENOLIC-COMPOUNDS | QUANTIFICATION | FOOD SCIENCE & TECHNOLOGY | POLYPHENOLS | NUTRITION & DIETETICS | FRACTIONS | ANTIOXIDANT | END-PRODUCTS AGES | CHEMISTRY, APPLIED | METHYLGLYOXAL | FOOD | Gallic Acid - pharmacology | Phenylethyl Alcohol - analogs & derivatives | Plant Extracts - pharmacology | Deoxyglucose - antagonists & inhibitors | Glycation End Products, Advanced - antagonists & inhibitors | Furaldehyde - analysis | Arginine - analogs & derivatives | Lysine - antagonists & inhibitors | Arginine - analysis | Tandem Mass Spectrometry | Deoxyglucose - analogs & derivatives | Arginine - antagonists & inhibitors | Chromatography, Liquid | Food Handling | Pyruvaldehyde - antagonists & inhibitors | Lysine - analysis | Plant Leaves - chemistry | Lysine - analogs & derivatives | Furaldehyde - antagonists & inhibitors | Furaldehyde - analogs & derivatives | Glycation End Products, Advanced - analysis | Maillard Reaction - drug effects | Deoxyglucose - analysis | Pyruvaldehyde - analysis | Flour - analysis | Phenylethyl Alcohol - pharmacology | Quercetin - pharmacology | Triticum - chemistry | Olea - chemistry | Medicine, Botanic | Analysis | Medicine, Herbal | Lysine
Journal Article
Journal of Endocrinology, ISSN 0022-0795, 08/2002, Volume 174, Issue 2, pp. 233 - 246
Glucose-dependent insulinotropic polypeptide (GIP) acts as a glucose-dependent growth factor for beta-cells. Here we show that GIP and glucose also act... 
PATHWAYS | IGF-I | RECEPTOR TYROSINE KINASES | ACTIVATED PROTEIN-KINASE | PHOSPHATIDYLINOSITOL 3-KINASE | MAP KINASE | ENDOCRINOLOGY & METABOLISM | ELEMENT-BINDING PROTEIN | INS-1 CELLS | GROWTH-FACTOR | FACTOR-I | Apoptosis - drug effects | Calcium - metabolism | Humans | Maleimides - pharmacology | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - analogs & derivatives | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | MAP Kinase Kinase 1 | Isoquinolines - pharmacology | Deoxyglucose - pharmacology | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Indoles - pharmacology | Flavonoids - pharmacology | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Gastric Inhibitory Polypeptide - pharmacology | B-Lymphocytes - metabolism | Cell Line | Enzyme Inhibitors - pharmacology | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Arginase - genetics | Protein Kinase C - antagonists & inhibitors | Chelating Agents - pharmacology | Calcium-Calmodulin-Dependent Protein Kinases - antagonists & inhibitors | Sulfonamides - pharmacology | Egtazic Acid - pharmacology | MAP Kinase Signaling System - drug effects | Mitosis - drug effects | Androstadienes - pharmacology | Signal Transduction - drug effects | Glucokinase - antagonists & inhibitors | Plasmids | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - pharmacology | Wortmannin | Genistein - pharmacology | Glucose - metabolism | Alloxan - pharmacology | Benzylamines - pharmacology | Protein-Tyrosine Kinases - antagonists & inhibitors
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 09/2012, Volume 361, Issue 1-2, pp. 213 - 218
► Intracerebroventricular administration of galanin antagonist sustains insulin resistance. ► Galanin in brain enhances GLUT4 contents in membranes of... 
GLUT4 | Insulin sensitivity | Intracerebroventricular injection | TRANSLOCATION | LIPID-METABOLISM | DISORDERS | RELEASE | EXERCISE | CELL BIOLOGY | MESSENGER-RNA | ENDOCRINOLOGY & METABOLISM | LOCUS-COERULEUS | FAT | RECEPTORS | EXPRESSION | Bradykinin - analogs & derivatives | Galanin - administration & dosage | Deoxyglucose - metabolism | Glucose Transporter Type 4 - metabolism | Rats, Wistar | Cholesterol - blood | Injections, Intraventricular | Body Weight - drug effects | Male | Peptide Fragments - pharmacology | Adipocytes - drug effects | Insulin - blood | RNA, Messenger - metabolism | Galanin - metabolism | Fasting - blood | Cell Membrane - metabolism | Hypothalamus - drug effects | Bradykinin - pharmacology | Cell Membrane - drug effects | Galanin - antagonists & inhibitors | Physical Conditioning, Animal | Peptide Fragments - administration & dosage | RNA, Messenger - genetics | Insulin Resistance | Rats | Adipocytes - pathology | Galanin - pharmacology | Gene Expression Regulation - drug effects | Diabetes Mellitus, Type 2 - blood | Animals | Hypothalamus - metabolism | Adipocytes - metabolism | Triglycerides - blood | Diabetes Mellitus, Type 2 - pathology | Glucose Clamp Technique | Blood Glucose - metabolism | Bradykinin - administration & dosage | Galanin - genetics | Type 2 diabetes | Neuropeptide Y | Medical colleges | Neuropeptides | Insulin resistance | Diabetes | Glucose | Dextrose
Journal Article
Food Research International, ISSN 0963-9969, 02/2017, Volume 92, pp. 56 - 63
Journal Article
Food and Function, ISSN 2042-6496, 05/2016, Volume 7, Issue 5, pp. 2213 - 2222
Glucitol-core containing gallotannins (GCGs) are polyphenols containing galloyl groups attached to a 1,5-anhydro-D-glucitol core, which is uncommon among... 
MAPLE ACER-SACCHARUM | PHYTOCHEMICALS | GLYCOXIDATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOOD SCIENCE & TECHNOLOGY | PREVENTION | RECEPTOR | RAGE | ENDPRODUCTS | BOVINE SERUM-ALBUMIN | METHYLGLYOXAL | PHENOLIC GLYCOSIDES | Plant Extracts - chemistry | Plant Extracts - pharmacology | Polyphenols - pharmacology | Deoxyglucose - antagonists & inhibitors | Free Radical Scavengers | Iron | Glycosylation - drug effects | Fructose - metabolism | Hydrolyzable Tannins - antagonists & inhibitors | Pyruvaldehyde - metabolism | Deoxyglucose - analogs & derivatives | Sorbitol - analogs & derivatives | Hydrolyzable Tannins - chemistry | Acer - chemistry | Inhibitory Concentration 50 | Digoxin - antagonists & inhibitors | Gallic Acid - analogs & derivatives | Gallic Acid - chemistry | Gallic Acid - antagonists & inhibitors | Serum Albumin, Bovine - drug effects | Electron Spin Resonance Spectroscopy | Protein Structure, Secondary | Sorbitol - chemistry | Digoxin - chemistry | Guanidines | Antioxidants - pharmacology | Glycoside Hydrolase Inhibitors - chemistry | Glycoside Hydrolase Inhibitors - pharmacology | Deoxyglucose - chemistry | Sorbitol - antagonists & inhibitors | Circular Dichroism - methods | Hypoglycemic Agents - pharmacology | Iron Chelating Agents - analysis | Pyruvaldehyde - analysis | Free Radicals - analysis | Glycation End Products, Advanced - metabolism | Glucosidases - drug effects | maple (Acer) | advanced glycation endproducts (AGEs) | glucitol-core containing gallotannins (GCGs) | metal chelating | free radical scavenging
Journal Article
Food & Function, ISSN 2042-6496, 2016, Volume 7, Issue 5, pp. 2213 - 2222
Glucitol-core containing gallotannins (GCGs) are polyphenols containing galloyl groups attached to a 1,5-anhydro-d-glucitol core, which is uncommon among... 
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 09/2002, Volume 22, Issue 17, pp. 7730 - 7736
Journal Article
Oncogene, ISSN 0950-9232, 05/2012, Volume 31, Issue 22, pp. 2738 - 2749
Targeting altered cancer cell metabolism with the glycolysis inhibitor, 2-deoxyglucose (2DG), is a viable therapeutic strategy, but the effects of 2DG on... 
Bcl-2 | Bax | Oncogenesis | 2-deoxyglucose (2DG) | BH3 mimetics | Apoptosis | MITOCHONDRIAL APOPTOSIS | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | apoptosis | 2-DEOXY-D-GLUCOSE | BH3 DOMAINS | MOUSE B-CELL | CELL BIOLOGY | IN-VITRO | METABOLISM | ONCOLOGY | oncogenesis | GENETICS & HEREDITY | STRESS | BH3-ONLY PROTEINS | Cell Proliferation | Immunoprecipitation | Thymocytes - metabolism | Lymphoma, T-Cell - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Caspases - metabolism | Flow Cytometry | Bcl-2-Like Protein 11 | Biphenyl Compounds - pharmacology | Nitrophenols - pharmacology | Deoxyglucose - pharmacology | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | Real-Time Polymerase Chain Reaction | bcl-2-Associated X Protein - genetics | Antimetabolites - pharmacology | Lymphoma, B-Cell - drug therapy | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Lymphoma, B-Cell - metabolism | Membrane Proteins - genetics | Mice, Inbred C57BL | RNA, Messenger - genetics | Cells, Cultured | bcl-2-Associated X Protein - metabolism | Antineoplastic Combined Chemotherapy Protocols | Proto-Oncogene Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Sulfonamides - pharmacology | Piperazines - pharmacology | Blotting, Western | Apoptosis Regulatory Proteins - metabolism | Lymphoma, T-Cell - drug therapy | Animals | Membrane Proteins - antagonists & inhibitors | Apoptosis Regulatory Proteins - antagonists & inhibitors | Lymphoma, B-Cell - pathology | Lymphoma, T-Cell - pathology | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Thymocytes - cytology | Mice | Proto-Oncogene Proteins c-bcl-2 - genetics | Care and treatment | Cancer cells | Physiological aspects | Glycolysis | Genetic aspects | Research | Non-Hodgkin's lymphomas | Oncology | Lymphomas | Toxicity | Index Medicus
Journal Article
Archives of Physiology and Biochemistry, ISSN 1381-3455, 10/2018, Volume 124, Issue 5, pp. 430 - 435
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 06/2011, Volume 163, Issue 3, pp. 624 - 637
BACKGROUND AND PURPOSE Although opioids have been reported to affect glucose homeostasis, relatively little is known on the role of δ‐opioid receptors. We have... 
glucose uptake | receptor tyrosine kinases | protein kinase Cζ | phosphatidylinositol 3‐kinase | Src tyrosine kinases | Akt | δ‐Opioid receptor | Chinese hamster ovary cells | δ-Opioid receptor | protein kinase CÎ | phosphatidylinositol 3-kinase | 3T3-L1 ADIPOCYTES | OXIDATIVE-PHOSPHORYLATION | protein kinase C zeta | TYROSINE KINASE | PROTEIN-COUPLED RECEPTORS | CYCLIC-AMP | HAMSTER OVARY CELLS | delta-Opioid receptor | HEXOKINASE-ACTIVITY | PHARMACOLOGY & PHARMACY | KINASE-C-ZETA | TRANSPORTER ISOFORMS | Deoxyglucose - metabolism | Cricetulus | Humans | Mitogen-Activated Protein Kinase 3 - antagonists & inhibitors | Male | Transfection | Biological Transport | Cyclic AMP - analogs & derivatives | Receptors, Opioid, delta - genetics | Glucose Transporter Type 1 - physiology | Cell Membrane - metabolism | src-Family Kinases - physiology | CHO Cells | Pertussis Toxin - pharmacology | Cricetinae | Mitogen-Activated Protein Kinase 1 - antagonists & inhibitors | src-Family Kinases - antagonists & inhibitors | Rats | Protein Kinase C - antagonists & inhibitors | Proto-Oncogene Proteins c-akt - physiology | Rats, Sprague-Dawley | Cyclic AMP - pharmacology | Animals | Receptor, IGF Type 1 - physiology | Glucose - metabolism | Phosphatidylinositol 3-Kinases - physiology | Kinetics | Receptors, Opioid, delta - agonists | Glucose Transporter Type 1 - antagonists & inhibitors | Receptors, Opioid, delta - physiology | Research Papers
Journal Article