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Journal of Controlled Release, ISSN 0168-3659, 01/2015, Volume 198, pp. 55 - 61
Inhaled antibiotics, such as tobramycin, for the treatment of pulmonary infections are associated with the increase in life expectancy seen in cystic fibrosis... 
Pseudomonas aeruginosa | Alginate | DNase | Tobramycin | Nanoparticle | Cystic fibrosis sputum | CHITOSAN/ALGINATE NANOPARTICLES | VIVO | DRUG-DELIVERY | SPUTUM | LUNG INFECTION | CHEMISTRY, MULTIDISCIPLINARY | BACTERIAL BIOFILMS | DEXTRAN SULFATE | IN-VITRO CHARACTERIZATION | GALLERIA-MELLONELLA | OCULAR DELIVERY | PHARMACOLOGY & PHARMACY | Recombinant Proteins - therapeutic use | Nanoparticles - chemistry | Humans | Pseudomonas aeruginosa - growth & development | Tobramycin - pharmacology | Deoxyribonuclease I - therapeutic use | Tobramycin - administration & dosage | Microbial Sensitivity Tests | Anti-Bacterial Agents - therapeutic use | Deoxyribonuclease I - chemistry | Deoxyribonuclease I - pharmacology | Nanoparticles - therapeutic use | Anti-Bacterial Agents - chemistry | Adult | Tobramycin - chemistry | Glucuronic Acid - chemistry | Tobramycin - therapeutic use | Pseudomonas Infections - drug therapy | Recombinant Proteins - chemistry | Treatment Outcome | DNA - metabolism | Hexuronic Acids - chemistry | Pseudomonas aeruginosa - drug effects | Recombinant Proteins - pharmacology | Deoxyribonuclease I - administration & dosage | Chemistry, Pharmaceutical | Recombinant Proteins - administration & dosage | Sputum - metabolism | Chitosan - chemistry | Alginates - chemistry | Anti-Bacterial Agents - pharmacology | Nanoparticles - administration & dosage | Anti-Bacterial Agents - administration & dosage | Cystic Fibrosis - drug therapy | Dornase alfa | Analysis | Cystic fibrosis | Polymers | Health aspects | Index Medicus
Journal Article
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 08/2016, Volume 55, Issue 36, pp. 10732 - 10736
Journal Article
ACS Applied Materials and Interfaces, ISSN 1944-8244, 08/2015, Volume 7, Issue 33, pp. 18707 - 18716
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 07/2015, Volume 209, pp. 150 - 158
Infections caused by biofilm-forming bacteria are a major threat to hospitalized patients and the main cause of chronic obstructive pulmonary disease and... 
Nanoparticles | Biofilm | Pseudomonas aeruginosa | Ciprofloxacin | DNase I | EFFICACY | MACROPHAGES | DEPOSITION | CHEMISTRY, MULTIDISCIPLINARY | CYSTIC-FIBROSIS PATIENTS | PSEUDOMONAS-AERUGINOSA | DISEASE | ANTIMICROBIAL PEPTIDE | PHARMACOLOGY & PHARMACY | NANOPRECIPITATION METHOD | POLYMER NANOPARTICLES | Nanoparticles - chemistry | Pseudomonas aeruginosa - growth & development | Drug Carriers - administration & dosage | Polylysine - chemistry | Drug Carriers - chemistry | Microbial Sensitivity Tests | Deoxyribonuclease I - chemistry | Deoxyribonuclease I - pharmacology | Anti-Bacterial Agents - chemistry | Cell Line | Lactic Acid - chemistry | Bacterial Infections - drug therapy | Extracellular Matrix - drug effects | Ciprofloxacin - pharmacology | Pseudomonas aeruginosa - drug effects | Deoxyribonuclease I - administration & dosage | Drug Carriers - pharmacology | DNA - chemistry | Animals | Biofilms | Ciprofloxacin - administration & dosage | Polyglycolic Acid - chemistry | Ciprofloxacin - chemistry | Drug Liberation | Anti-Bacterial Agents - pharmacology | Mice | Nanoparticles - administration & dosage | Staphylococcus aureus - drug effects | Staphylococcus aureus - growth & development | Anti-Bacterial Agents - administration & dosage | Bacterial infections | Antibiotics | Health aspects | Drugs | Medical research | Nucleases | Lung diseases, Obstructive | Drug delivery systems | Cystic fibrosis | Vehicles | Lysine | Medicine, Experimental | Bacteria | Research institutes | Index Medicus | Enginyeria química | polymer nanoparticles | disease | deposition | cystic-fibrosis patients | nanoprecipitation method | efficacy | macrophages | pseudomonas-aeruginosa | Antibiòtics | antimicrobial peptide | Enginyeria de teixits | Àrees temàtiques de la UPC
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 09/2004, Volume 126, Issue 37, pp. 11484 - 11499
We have earlier reported the synthesis and antisense properties of the conformationally constrained oxetane-C and -T containing oligonucleotides, which have... 
RNA HYBRID DUPLEX | STEREOCHEMICAL ASSIGNMENTS | BIOLOGICAL-ACTIVITY | CARBOCYCLIC THYMIDINE | NUCLEIC-ACID ANALOGS | MODIFIED ANTISENSE OLIGONUCLEOTIDES | BICYCLIC NUCLEOSIDES | CONFORMATIONALLY LOCKED NUCLEOSIDES | SUGAR RING | CHEMISTRY, MULTIDISCIPLINARY | H CLEAVAGE | Oligonucleotides - chemistry | Humans | Molecular Sequence Data | Cytidine - analogs & derivatives | Nucleic Acid Heteroduplexes - metabolism | Ethers, Cyclic - metabolism | Thermodynamics | Ethers, Cyclic - chemistry | Deoxyribonuclease I - chemistry | Guanosine - chemistry | Base Sequence | Adenosine - chemistry | Nucleic Acid Conformation | Circular Dichroism | Thymidine - chemistry | RNA - metabolism | Guanosine - analogs & derivatives | Cytidine - chemistry | Models, Molecular | RNA - chemistry | Oligonucleotides - chemical synthesis | Nucleic Acid Heteroduplexes - chemistry | Deoxyribonuclease I - metabolism | Oligonucleotides - metabolism | Thymidine - analogs & derivatives | Adenosine - analogs & derivatives | Ribonuclease H - chemistry | Kinetics | Oligonucleotides - blood | Ribonuclease H - metabolism | Adenosine | DNA microarrays | Research | Chemical properties | Guanosine | Index Medicus | Models; Molecular | Deoxyribonuclease I/chemistry/metabolism | Oligonucleotides/blood/chemical synthesis/chemistry/metabolism | RNA/chemistry/metabolism | Cytidine/analogs & derivatives/chemistry | Guanosine/analogs & derivatives/chemistry | Thymidine/analogs & derivatives/chemistry | Adenosine/analogs & derivatives/chemistry | Ethers; Cyclic/chemistry/metabolism | Nucleic Acid Heteroduplexes/chemistry/metabolism | Research Support; Non-U.S. Gov't | Ribonuclease H; Calf Thymus/chemistry/metabolism
Journal Article
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2018, Volume 1577, pp. 155 - 160
Journal Article
Journal of Immunological Methods, ISSN 0022-1759, 09/2014, Volume 411, pp. 55 - 65
Effects of exosomes present in human plasma on immune cells have not been examined in detail. Immunological studies with plasma-derived exosomes require their... 
Exosome isolation | Immunological studies | Size-exclusion chro