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Nature, ISSN 0028-0836, 09/2012, Volume 489, Issue 7414, pp. 75 - 82
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2011, Volume 6, Issue 12, p. e28616
The PAX6 gene plays a crucial role in development of the eye, brain, olfactory system and endocrine pancreas. Consistent with its pleiotropic role the gene... 
EYE | ANIRIDIA | ELEMENTS | CELLS | HOMEOBOX-CONTAINING GENE | HUMAN GENOME | MOUSE | BIOLOGY | MICE | DIFFERENTIATION | EXPRESSION | Paired Box Transcription Factors - genetics | Conserved Sequence - genetics | Species Specificity | Homeodomain Proteins - metabolism | Humans | Genetic Loci - genetics | Neuroepithelial Cells - cytology | Gene Expression Regulation, Developmental | Eye Proteins - genetics | Repressor Proteins - metabolism | Green Fluorescent Proteins - metabolism | Mice, Inbred C57BL | Repressor Proteins - genetics | Mice, Transgenic | PAX6 Transcription Factor | Genetic Markers | Homeodomain Proteins - genetics | Deoxyribonuclease I - metabolism | Animals | Eye Proteins - metabolism | Enhancer Elements, Genetic - genetics | Mice | Neuroepithelial Cells - metabolism | Homeostasis - genetics | Paired Box Transcription Factors - metabolism | Nucleases | Allergy | Genetic engineering | Allergic reaction | Analysis | Genes | Brain | Spinal cord | Leukocyte migration | Genomics | Spatial discrimination | Genomes | Regulatory sequences | Gene deletion | Olfactory system | Eye | Developmental stages | Clonal deletion | Coding | Aniridia | Deletion | Genetics | Pancreas | Drug dosages | Deoxyribonucleic acid--DNA | CpG islands | Medical research | Breakpoints | Deoxyribonuclease | Hypersensitivity | Feature recognition | Transgenic mice | Mammals | Gene expression | Epithelium | Loci | Medicine | Pax6 protein | Enhancers | Hospitals | Insects | Councils | Hindbrain | Nuclei (cytology) | Gene mapping | Cell migration | Deoxyribonucleic acid | DNA
Journal Article
Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 2009, Volume 34, Issue 4, pp. 405 - 415
Transcriptional activators and coactivators overcome repression by chromatin, but regulation of chromatin disassembly and coactivator binding to promoters is... 
DNA | RNA-POLYMERASE-II | ACETYLTRANSFERASE COMPLEX | ACIDIC ACTIVATION DOMAINS | TRANSCRIPTIONAL ACTIVATION | HISTONE CHAPERONE ASF1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | CELL-CYCLE | SACCHAROMYCES-CEREVISIAE | ELONGATION-FACTORS | DNA-REPLICATION | CELL BIOLOGY | Chromatin - metabolism | Molecular Chaperones - metabolism | Saccharomyces cerevisiae - genetics | Deoxyribonucleases, Type II Site-Specific - genetics | DNA-Binding Proteins - metabolism | Saccharomyces cerevisiae - metabolism | Trans-Activators - genetics | Cell Cycle Proteins - genetics | Transcriptional Elongation Factors - genetics | Chromatin - chemistry | Gene Expression Regulation, Fungal | Promoter Regions, Genetic | Chromosomal Proteins, Non-Histone - metabolism | High Mobility Group Proteins - metabolism | Cell Cycle Proteins - metabolism | Molecular Chaperones - genetics | Nucleosomes - metabolism | Saccharomyces cerevisiae Proteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Chromosomal Proteins, Non-Histone - genetics | Transcription Factors - metabolism | Transcriptional Elongation Factors - metabolism | Deoxyribonucleases, Type II Site-Specific - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Cell Cycle - physiology | Trans-Activators - metabolism | Chromatin - genetics | High Mobility Group Proteins - genetics | Proteins | Nucleosomes | Protein binding
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2010, Volume 107, Issue 26, pp. 12028 - 12033
We report here an efficient method for targeted mutagenesis of Arabidopsis genes through regulated expression of zinc finger nucleases (ZFNs)—enzymes... 
Polymerase chain reaction | Mutagenesis | DNA | Genes | Genomes | Genetic engineering | Plants | Genetic mutation | Transgenic plants | Zinc | Alcohol dehydrogenase | Nonhomologous end-joining | Gene knockout | Chalcone synthase | TRANSFORMATION | STEM-CELLS | chalcone synthase | INFORMATION | MULTIDISCIPLINARY SCIENCES | TRANSGENIC PLANTS | alcohol dehydrogenase | ARRAYS | gene knockout | MUTANTS | POOL ENGINEERING OPEN | FLORAL DIP | nonhomologous end-joining | GENE DISRUPTION | EXPRESSION | Gene Targeting | Arabidopsis Proteins - genetics | Mutagenesis, Site-Directed | Genes, Plant | Saccharomyces cerevisiae - genetics | Molecular Sequence Data | DNA, Plant - metabolism | Deoxyribonucleases - metabolism | Arabidopsis - metabolism | Arabidopsis - genetics | Saccharomyces cerevisiae - metabolism | Deoxyribonucleases - genetics | Protoplasts - metabolism | Base Sequence | DNA Repair | Plants, Genetically Modified | Alcohol Dehydrogenase - genetics | Protein Engineering | Zinc Fingers - genetics | DNA, Plant - genetics | Arabidopsis thaliana | Genetic aspects | Zinc finger proteins | Properties | Index Medicus | Transformation | Seeds | DNA damage | Chromosome deletion | Promoters | targeted mutagenesis | Seedlings | DNA-binding protein | Anthocyanins | Mutation | Nuclease | Chromosomes | allyl alcohol | DNA sequencing | Biological Sciences
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 09/2018, Volume 46, Issue 17, pp. 8917 - 8925
Journal Article