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British Journal of Pharmacology, ISSN 0007-1188, 03/2013, Volume 168, Issue 6, pp. 1445 - 1455
Background and Purpose The Sigma‐1 receptor (Sig1R) impacts on calcium ion signalling and has a plethora of ligands. This study investigated Sig1R and its... 
cationic channels | endothelial cells | histamine | calcium channels | vascular endothelial growth factor | hydrogen peroxide | Sigma‐1 receptor | TRP channels | Sigma-1 receptor | ACTIVATION | ANGIOGENESIS | DEPENDENCE | INTRACELLULAR CA2 | CALCIUM | PHARMACOLOGY & PHARMACY | Endothelium, Vascular - cytology | Humans | Endothelium, Vascular - drug effects | Protein Transport - drug effects | Receptors, sigma - antagonists & inhibitors | Vascular Endothelial Growth Factor A - metabolism | Histamine - metabolism | RNA Interference | Membrane Transport Modulators - pharmacology | HEK293 Cells | Receptors, sigma - metabolism | TRPC Cation Channels - genetics | Membrane Potentials - drug effects | Recombinant Proteins - metabolism | Recombinant Proteins - antagonists & inhibitors | Cells, Cultured | Receptors, sigma - agonists | Receptors, sigma - genetics | TRPC Cation Channels - antagonists & inhibitors | Patch-Clamp Techniques | TRPM Cation Channels - antagonists & inhibitors | Calcium Signaling - drug effects | Endothelium, Vascular - metabolism | TRPC Cation Channels - metabolism | TRPM Cation Channels - genetics | Ligands | RNA, Small Interfering | TRPM Cation Channels - metabolism | Kinetics | Fluorescence | Histamine | Calcium channels | Hydrogen peroxide | Vascular endothelial growth factor | Endothelium | Research Papers
Journal Article
Journal of Pharmacy and Pharmacology, ISSN 0022-3573, 06/2019, Volume 71, Issue 6, pp. 988 - 995
Objectives TGF‐β through hyperelongation of glycosaminoglycan (GAG) chains leads to binding of low‐density lipoproteins to the proteoglycans. The vasoactive... 
atherosclerosis | ETB receptor | Smad2C | TGF‐β | endothelin‐1 | transactivation | TGF-beta | ELONGATION | PROTEIN-COUPLED RECEPTORS | ETA-RECEPTOR | PHARMACOLOGY & PHARMACY | endothelin-1 | EGF RECEPTOR | Amides - pharmacology | Phosphorylation - physiology | Receptor, Endothelin B - drug effects | Endothelial Cells - metabolism | Endothelin-1 - metabolism | Cells, Cultured | Cytochalasin D - pharmacology | Blotting, Western | Receptor, Transforming Growth Factor-beta Type I - metabolism | Animals | Piperidines - pharmacology | Receptors, Transforming Growth Factor beta - metabolism | Time Factors | rho-Associated Kinases - metabolism | Cattle | N-Acetylgalactosaminyltransferases - genetics | Pyridines - pharmacology | Receptor, Endothelin B - metabolism | Transcriptional Activation - physiology | Aorta - cytology | Oligopeptides - pharmacology | Transforming Growth Factor beta - metabolism | Phosphorylation | Matrix metalloproteinases | Glycosaminoglycans | Endothelin | Transforming growth factor | Cytochalasin D | Matrix metalloproteinase | Kinases | Western blotting | Proteins | Time dependence | Signal transduction | Actin | Vasoactive agents | Smad2 protein | Atherosclerosis | Aorta | Metalloproteinase | Inhibition | Growth factors | Proteoglycans | Polymerization | Endothelial cells | Rho-associated kinase | Intermediates | Signaling | Lipoproteins | Inhibitors | Arteriosclerosis | Cytoskeleton
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2011, Volume 108, Issue 22, pp. 9268 - 9273
Journal Article
by He, SQ and Zhang, ZN and Guan, JS and Liu, HR and Zhao, B and Wang, HB and Li, QA and Yang, H and Luo, J and Li, ZY and Wang, QO and Lu, YJ and Bao, L and Zhang, X
NEURON, ISSN 0896-6273, 01/2011, Volume 69, Issue 1, pp. 120 - 131
delta-opioid receptors (DORs) form heteromers with mu-opioid receptors (MORs) and negatively regulate MOR-mediated spinal analgesia. However, the underlying... 
RAT SPINAL-CORD | KNOCK-OUT MICE | TOLERANCE | PHYSICAL-DEPENDENCE | DOWN-REGULATION | DORSAL-ROOT GANGLIA | PROTEIN-COUPLED RECEPTORS | MORPHINE ANALGESIA | SUBSTANCE-P | NEUROSCIENCES | NOXIOUS THERMAL STIMULI
Journal Article