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International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 06/2018, Volume 99, pp. 147 - 153
Depurination is accelerated by heat and reactive oxygen species under physiological conditions. We previously reported that polyamines are involved in... 
Thermus thermophilus | Polyamine | Unusual polyamines | Standard polyamines | Depurination | DECARBOXYLASE | STIMULATION | ANALOGS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | SPERMINE | DNA DEPURINATION | CELL BIOLOGY | EXTREME THERMOPHILE | MESSENGER-RNA | THERMUS-THERMOPHILUS | BINDING | Proteins | Antioxidants | Physiological aspects | Polyamines | Transfer RNA | Index Medicus
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 07/2019, Volume 9, Issue 1, pp. 9663 - 12
Owing to its longevity and enormous information density, DNA, the molecule encoding biological information, has emerged as a promising archival storage medium.... 
DEPURINATION | MICROARRAYS | CELL | MULTIDISCIPLINARY SCIENCES | DIGITAL INFORMATION | Deoxyribonucleic acid--DNA | DNA sequencing
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2007, Volume 104, Issue 37, pp. 14616 - 14621
Journal Article
ELECTROPHORESIS, ISSN 0173-0835, 11/2014, Volume 35, Issue 21-22, pp. 3134 - 3144
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 08/2018, Volume 129, pp. 80 - 87
Oligonucleotide-based therapeutics have been implemented as a new therapeutic modality in biotech industry, which offers the opportunity to develop formulation... 
Biopharmaceuticals characterization | Stability | Forced conditions | Formulation | Oligonucleotides | PROTEIN | RNA | LOCKED NUCLEIC-ACID | VISCOSITY | SHEAR | DNA | DEPURINATION | DEGRADATION | PHARMACOLOGY & PHARMACY | ANTISENSE OLIGONUCLEOTIDES | Biological products | Lysine | Analysis | Therapeutics | Product development | Nucleic acids | Homeopathy | Materia medica and therapeutics | Index Medicus
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 06/2013, Volume 135, Issue 24, pp. 9121 - 9129
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2011, Volume 286, Issue 42, pp. 36316 - 36321
Journal Article
Tetrahedron, ISSN 0040-4020, 03/2017, Volume 73, Issue 11, pp. 1424 - 1435
We synthesized the DNA oligonucleotide containing a new cross-linkable 4-amino-2-oxo-6-vinyltriazine (AOVT) nucleobase analogue (Et-AOVT) and evaluated these... 
Vinyl triazine | Nucleic acid binding proteins | Crosslink | Oligonucleotides | THERAPEUTICS | MECHANISM | OLIGODEOXYRIBONUCLEOTIDE | CHEMISTRY, ORGANIC | LINKING | INHIBITION | MESSENGER-RNA | KINETICS | GENE-EXPRESSION | DEPURINATION | Purines | Crosslinked polymers | Hydrogen | Analysis | DNA | Proteins | Protein binding
Journal Article
Toxins, ISSN 2072-6651, 03/2019, Volume 11, Issue 3, p. 174
Ricin and abrin are ribosome-inactivating proteins leading to inhibition of protein synthesis and cell death. These toxins are considered some of the most... 
holomonitor | abrin | digital holographic microscopy | morphology | ricin | intoxication | APOPTOSIS | RNA | MECHANISM | A-CHAIN | TOXIN | FOOD SCIENCE & TECHNOLOGY | RESISTANCE | DEPURINATION | TOXICOLOGY | ENZYMATIC-ACTIVITY | RIBOSOME-INACTIVATING PROTEINS | CYTOTOXICITY
Journal Article
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, ISSN 0027-5107, 08/2015, Volume 778, pp. 11 - 17
The human β-globin, δ-globin and e{open}-globin genes contain almost identical coding strand sequences centered about codon 6 having potential to form a... 
Human β-globin gene paralogs | DNA stem-loop structures | DNA self-depurination mechanism | DNA self-catalyzed depurination | HB β, δ, e{open}1, γ1, γ2 genes
Journal Article
Scientific Reports, ISSN 2045-2322, 02/2017, Volume 7, Issue 1, pp. 42912 - 42912
Ricin toxin A chain (RTA) binds to stalk P-proteins to reach the alpha-sarcin/ricin loop (SRL) where it cleaves a conserved adenine. Arginine residues at the... 
RNA | A-CHAIN | ACTIVE-SITE | TOXIN | MULTIDISCIPLINARY SCIENCES | DEPURINATION | TRICHOSANTHIN | ENDOPLASMIC-RETICULUM | SACCHAROMYCES-CEREVISIAE | INACTIVATING PROTEINS | INSIGHTS | Proteins | Toxin A | Arginine | Ricin | Toxicity | Adenine | Mutation | Hydrophobicity | Electrostatic properties | Index Medicus
Journal Article
Toxins, ISSN 2072-6651, 08/2019, Volume 11, Issue 8, p. 450
Ricin is a member of the ribosome-inactivating protein (RIP) family of toxins and is classified as a biothreat agent by the Centers for Disease Control and... 
SIGNALING PATHWAYS | ricin | apoptosis | cathepsin | toxin-mediated diseases | TUMOR-NECROSIS-FACTOR | IN-VITRO | INHIBITION | tumor necrosis factor | toxins | GENE-EXPRESSION | DEPURINATION | fas | cytokines | TRAIL-INDUCED APOPTOSIS | TOXICOLOGY | Z-FA-FMK | caspases | CYSTEINE PROTEASES | CATHEPSIN-B | Index Medicus
Journal Article