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Journal of Biological Chemistry, ISSN 0021-9258, 1782, Volume 289, Issue 21, pp. 14925 - 14940
Adducin is a protein organizing the cortical actin cytoskeleton and a target of RhoA and PKC signaling. However, the role for intercellular cohesion is... 
SH2 DOMAIN | PROTEIN-KINASE-C | PEMPHIGUS-VULGARIS-IGG | INOSITOL 1,4,5-TRISPHOSPHATE | INTRACELLULAR CALCIUM | BIOCHEMISTRY & MOLECULAR BIOLOGY | RHO GTPASES | ACTIN CYTOSKELETON | DESMOGLEIN 3 | CELL CARCINOMA LINE | DJM-1 CELLS | rhoA GTP-Binding Protein - immunology | Calcium - metabolism | Cytoskeletal Proteins - genetics | Humans | Calcium - immunology | rhoA GTP-Binding Protein - metabolism | Green Fluorescent Proteins - genetics | Serine - immunology | Autoantibodies - pharmacology | RNA Interference | Protein Kinase C - metabolism | Desmosomes - immunology | Cytoskeletal Proteins - metabolism | Phosphorylation - immunology | Desmoglein 3 - metabolism | Phosphorylation - drug effects | Calmodulin-Binding Proteins - genetics | Cell Line | Desmoglein 3 - immunology | Desmosomes - metabolism | Green Fluorescent Proteins - metabolism | Cell Adhesion - genetics | Calmodulin-Binding Proteins - immunology | Calmodulin-Binding Proteins - metabolism | Protein Kinase C - immunology | Serine - metabolism | Blotting, Western | Keratinocytes - immunology | Cell Adhesion - immunology | Microscopy, Confocal | Autoantibodies - immunology | Cytoskeletal Proteins - immunology | Keratinocytes - drug effects | Desmoglein 3 - genetics | Keratinocytes - metabolism | Pemphigus - immunology | Microscopy, Fluorescence | Rho GTPases | Actin | Adducin | Pemphigus | Protein Kinase C (PKC) | Desmosome | Cell Biology
Journal Article
Oncogene, ISSN 0950-9232, 05/2014, Volume 33, Issue 18, pp. 2363 - 2374
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, p. e64088
Desmoglein 3 (DSG3) is a component of the desmosome, which confers strong cell-cell adhesion. Previously, an oncogenic function of DSG3 has been found in head... 
LUNG-CANCER | HEAD NECK-CANCER | PLAKOGLOBIN EXPRESSION | MOLECULAR TARGET | MULTIDISCIPLINARY SCIENCES | ORAL-CANCER | GAMMA-CATENIN | ADHERENS JUNCTIONS | HUMAN BREAST-CANCER | BETA-CATENIN | CARCINOMA | Cyclin D1 - metabolism | Cell Proliferation | Humans | Gene Expression Regulation, Neoplastic | Male | Resting Phase, Cell Cycle | Head and Neck Neoplasms - metabolism | Gene Knockdown Techniques | DNA-Binding Proteins - metabolism | TCF Transcription Factors - metabolism | Cell Nucleus - metabolism | Desmoglein 3 - deficiency | G1 Phase Cell Cycle Checkpoints | Active Transport, Cell Nucleus | Desmoglein 3 - metabolism | Signal Transduction | Neoplasm Invasiveness | Gene Silencing | gamma Catenin - metabolism | Proto-Oncogene Proteins c-myc - metabolism | Head and Neck Neoplasms - pathology | Phenotype | Animals | Cell Transformation, Neoplastic | Desmoglein 3 - genetics | Cell Line, Tumor | Head and Neck Neoplasms - genetics | Mice | Matrix Metalloproteinases - metabolism | Cell Movement | Analysis | Cancer | Biotechnology | Phosphorylation | Thoracic surgery | Immunoprecipitation | Laboratories | Downstream effects | Leukemia | Genes | c-Myc protein | Oncology | Myc protein | Kinases | Cyclin D1 | Cell adhesion & migration | Proteins | Signal transduction | Cell growth | Adhesive strength | Xenografts | Cell adhesion | Neck | Catenin | G1 phase | Desmoglein 3 | Translocation | Cloning | Breast cancer | Gene expression | LEF protein | Signaling | Medical prognosis | Head & neck cancer | Immunofluorescence | Cell migration | Cytoplasm | Tumors | Matrilysin
Journal Article
Human Pathology, ISSN 0046-8177, 2013, Volume 44, Issue 2, pp. 164 - 172
Journal Article
Journal of biochemistry, ISSN 0021-924X, 12/2018, Volume 164, Issue 6, pp. 471 - 481
It is ideal for the target antigen of a cytotoxic therapeutic antibody against cancer to be cancer-specific, but such antigens are rare. Thus an alternative... 
AUTOANTIBODIES | TARGET | LOCALIZATION | MEDIATED CYTOTOXICITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | IGG | HM1.24 | pemphigus vulgaris | AFFINITY | DSG3 | epitope | monoclonal antibody | MONOCLONAL-ANTIBODIES | PROTEINS | EXPRESSION | squamous cell carcinoma | Antibody Specificity | Epitopes - metabolism | Cricetulus | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - therapeutic use | Recombinant Fusion Proteins - metabolism | Desmoglein 3 - chemistry | Drug Design | Desmoglein 3 - metabolism | Peptide Fragments - genetics | CHO Cells | Cell Line | Cell Survival - drug effects | Peptide Fragments - metabolism | Antibodies, Monoclonal - pharmacology | Mice, Transgenic | Recombinant Fusion Proteins - chemistry | Epitopes - genetics | Mice, SCID | Carcinoma, Squamous Cell - immunology | Keratinocytes - immunology | Antineoplastic Agents, Immunological - pharmacology | Mice, Knockout | Xenograft Model Antitumor Assays | Antineoplastic Agents, Immunological - adverse effects | Keratinocytes - pathology | Peptide Fragments - chemistry | Animals | Carcinoma, Squamous Cell - drug therapy | Keratinocytes - drug effects | Tumor Burden - drug effects | Antineoplastic Agents, Immunological - therapeutic use | Desmoglein 3 - genetics | Keratinocytes - metabolism | Peptide Fragments - antagonists & inhibitors | Cell Line, Tumor | Desmoglein 3 - antagonists & inhibitors | Epitopes - chemistry | Mice | Mice, Inbred BALB C | Regular Papers
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 02/2011, Volume 131, Issue 2, pp. 410 - 417
Journal Article