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PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, p. e72857
Journal Article
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 11/2010, Volume 299, Issue 5, pp. H1328 - H1338
Xu J, Carretero OA, Liao TD, Peng H, Shesely EG, Xu J, Liu TS, Yang JJ, Reudelhuber TL, Yang XP. Local angiotensin II aggravates cardiac remodeling in... 
Cardiac hypertrophy | Oxidative stress | Inflammation | Fibrosis | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | NOX2-CONTAINING NADPH OXIDASE | MYOCYTES | HEART-FAILURE | RECEPTOR | HYPERTROPHY | INFARCTION | inflammation | PERIPHERAL VASCULAR DISEASE | fibrosis | MICE | cardiac hypertrophy | oxidative stress | Angiotensin II - genetics | Tetrazoles - pharmacology | Membrane Glycoproteins - metabolism | Valsartan | Oxidative Stress - physiology | Transforming Growth Factor beta1 - metabolism | NADPH Oxidases - metabolism | Male | Phosphatidylinositol 3-Kinases - metabolism | Dinoprost - metabolism | Angiotensin II Type 1 Receptor Blockers - pharmacology | Desoxycorticosterone - adverse effects | Hypertension - chemically induced | Myocardium - metabolism | Heart Rate - physiology | Dinoprost - analogs & derivatives | Proto-Oncogene Proteins c-akt - metabolism | Disease Models, Animal | Angiotensin II - metabolism | Valine - analogs & derivatives | Mice, Transgenic | Myocardium - pathology | Renin-Angiotensin System - physiology | Desoxycorticosterone - analogs & derivatives | NADPH Oxidase 2 | Hypertension - physiopathology | Hypertension - metabolism | Collagen - metabolism | Animals | Myocytes, Cardiac - drug effects | Receptor, Angiotensin, Type 1 - metabolism | Myocytes, Cardiac - metabolism | Renin-Angiotensin System - drug effects | Mice | Apoptosis - physiology | Valine - pharmacology | Hypertension | Heart enlargement | Angiotensin | Physiological aspects | Development and progression | Genetic aspects | Research | Risk factors
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 8, pp. 3013 - 3027
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 05/2002, Volume 22, Issue 9, pp. 3795 - 3805
Stress affects seizure susceptibility in animals and humans, but the underlying mechanisms are obscure. Here, we provide evidence that GABA(A)... 
Finasteride | 5α,3α -tetrahydrodeoxycorticosterone (3α,21-dihydroxy-5α-pregnan-20-one) | Kindling | Pentylenetetrazol | Deoxycorticosterone | Neurosteroid | Seizure | Indomethacin | 5α-dihydrodeoxycorticosterone | Stress | 5 alpha-dihydrodeoxycorticosterone | ENHANCED ANTICONVULSANT ACTIVITY | stress | pentylenetetrazol | CATAMENIAL EPILEPSY | seizure | 5 alpha,3 alpha-tetrahydrodeoxycorticosterone (3 alpha,21-dihydroxy-5 alpha-pregnan-20-one) | TEMPORAL-LOBE EPILEPSY | SWIM STRESS | deoxycorticosterone | STEROID 5-ALPHA-REDUCTASE | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | indomethacin | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE | GABA(A) receptor | AMINOBUTYRIC ACID(A) RECEPTOR | NEUROACTIVE STEROIDS | RAT-BRAIN | finasteride | neurosteroid | kindling | Corticosterone - pharmacology | Disease Susceptibility - physiopathology | Motor Activity - drug effects | Desoxycorticosterone - pharmacology | Male | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Seizures - chemically induced | Dose-Response Relationship, Drug | Kindling, Neurologic - drug effects | Seizures - physiopathology | Exercise Test | Finasteride - pharmacology | Desoxycorticosterone - antagonists & inhibitors | Steroids - metabolism | Stress, Physiological - metabolism | Corticosterone - analogs & derivatives | Receptors, GABA-A - drug effects | Steroids - pharmacology | Corticosterone - antagonists & inhibitors | Drug Resistance | Enzyme Inhibitors - pharmacology | 5-alpha Reductase Inhibitors | Rats | Steroids - antagonists & inhibitors | Desoxycorticosterone - analogs & derivatives | Rats, Sprague-Dawley | Indomethacin - pharmacology | Adrenalectomy | Animals | Drug Antagonism | Desoxycorticosterone - metabolism | Convulsants | Corticosterone - metabolism | Mice | Pentylenetetrazole | Receptors, GABA-A - metabolism
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2016, Volume 291, Issue 35, pp. 18474 - 18483
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2003, Volume 111, Issue 8, pp. 1201 - 1209
Tetrahydrobiopterin is a critical cofactor for the NO synthases, and in its absence these enzymes become "uncoupled," producing reactive oxygen species (ROSs)... 
ANION PRODUCTION | MEDICINE, RESEARCH & EXPERIMENTAL | NADPH OXIDASE | NAD(P)H OXIDASE | STIMULATES SUPEROXIDE PRODUCTION | ANGIOTENSIN-II | HYDROGEN-PEROXIDE | DEFICIENT MICE | KAPPA-B | ASCORBIC-ACID | SMOOTH-MUSCLE CELLS
Journal Article
Kidney International, ISSN 0085-2538, 07/2011, Volume 80, Issue 1, pp. 51 - 60
We assessed the relative contribution of the mitochondrial respiratory chain and NADPH (nicotinamide adenine dinucleotide phosphate) oxidase to... 
hypertension | mitochondria | NADPH oxidase | oxidative stress | RESPIRATORY-CHAIN | VASCULAR OXIDATIVE STRESS | SENSITIVE K+ CHANNELS | ANGIOTENSIN-II | COMPLEX-III | REACTIVE OXYGEN | METAIODOBENZYLGUANIDINE MIBG | NITRIC-OXIDE | UROLOGY & NEPHROLOGY | SUPEROXIDE PRODUCTION | DYSFUNCTION | Electron Transport - drug effects | Membrane Glycoproteins - metabolism | Humans | Nitrogen Oxides - urine | NADPH Oxidases - metabolism | Male | NADPH Oxidases - deficiency | Hypertension - chemically induced | Acetophenones - pharmacology | Rotenone - pharmacology | Rotenone - toxicity | NADPH Oxidases - genetics | Albuminuria - metabolism | Blood Pressure - drug effects | Dinoprost - analogs & derivatives | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Cell Line | Dinoprost - urine | Mice, Inbred C57BL | NADPH Oxidases - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Aldosterone - pharmacology | Sodium Chloride - administration & dosage | Mitochondria - metabolism | Mitochondria - drug effects | Desoxycorticosterone - analogs & derivatives | NADPH Oxidase 2 | Hypertension - physiopathology | Hypertension - metabolism | Membrane Glycoproteins - genetics | Mice, Knockout | Animals | Albuminuria - chemically induced | Mice | Oxidative Stress - drug effects | Membrane Glycoproteins - deficiency | Desoxycorticosterone - toxicity
Journal Article