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Molecular Cancer Therapeutics, ISSN 1535-7163, 10/2003, Volume 2, Issue 10, pp. 971 - 984
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Immunology, ISSN 0019-2805, 05/2013, Volume 139, Issue 1, pp. 19 - 29
Summary Bile acids (BAs) play important roles not only in lipid metabolism, but also in signal transduction. TGR5, a transmembrane receptor of BAs, is an... 
intestinal macrophage | TGR5 | tumour necrosis factor α | Crohn's disease | bile acid | Tumour necrosis factor α | Intestinal macrophage | Bile acid | Life Sciences & Biomedicine | Immunology | Science & Technology | Cholagogues and Choleretics - pharmacology | Intestinal Mucosa - metabolism | Dendritic Cells - immunology | Humans | Antigens, Bacterial - immunology | Crohn Disease - metabolism | Dendritic Cells - pathology | Male | Monocytes - metabolism | Monocytes - immunology | Receptors, G-Protein-Coupled - immunology | Signal Transduction - immunology | Lithocholic Acid - pharmacology | Intestinal Mucosa - immunology | Monocytes - pathology | Macrophage Colony-Stimulating Factor - pharmacology | Transcription Factor RelA - immunology | Female | Dendritic Cells - metabolism | Macrophages - immunology | Cytokines - immunology | Detergents - pharmacology | Macrophages - pathology | Gene Expression Regulation - immunology | Cells, Cultured | Proto-Oncogene Proteins c-fos - metabolism | Proto-Oncogene Proteins c-fos - immunology | Receptors, G-Protein-Coupled - biosynthesis | Crohn Disease - immunology | Crohn Disease - therapy | Gene Expression Regulation - drug effects | Macrophages - metabolism | Deoxycholic Acid - pharmacology | Signal Transduction - drug effects | Transcription Factor RelA - metabolism | Crohn Disease - pathology | Lipopolysaccharides - pharmacology | Receptors, G-Protein-Coupled - antagonists & inhibitors | Antigens, Bacterial - metabolism | Cytokines - biosynthesis | Interferon-gamma - pharmacology | Intestinal Mucosa - pathology | Cytokines | Dendritic cells | Gastrointestinal diseases | Biological response modifiers | Macrophages | Mitogens | Deoxycholic acid | Inflammatory bowel disease | Signal transduction | Immune system | Crohns disease | Index Medicus | Original
Journal Article
Journal Article
Journal Article
BMC pharmacology & toxicology, ISSN 2050-6511, 05/2019, Volume 20, Issue 1, pp. 33 - 33
Journal Article
PloS one, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, pp. e60770 - e60770
Topoisomerase inhibitors are effective for antibacterial and anticancer therapy because they can lead to the accumulation of the intermediate DNA cleavage... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Depsides - isolation & purification | Small Molecule Libraries - pharmacology | Escherichia coli - drug effects | Humans | Ascomycota - chemistry | Biological Products - pharmacology | Depsides - pharmacology | Depsides - toxicity | Dose-Response Relationship, Drug | Topoisomerase Inhibitors - pharmacology | Hydroxybenzoates - pharmacology | Yersinia pestis - drug effects | Anti-Bacterial Agents - toxicity | Drug Evaluation, Preclinical | Cell Survival - drug effects | Detergents - pharmacology | Escherichia coli - enzymology | DNA Topoisomerases, Type I - metabolism | Topoisomerase Inhibitors - toxicity | Anti-Bacterial Agents - isolation & purification | Magnesium - pharmacology | Hydroxybenzoates - isolation & purification | Topoisomerase Inhibitors - isolation & purification | High-Throughput Screening Assays | Anti-Bacterial Agents - pharmacology | Hydroxybenzoates - toxicity | Yersinia pestis - enzymology | Biological products | Cell death | Antibacterial agents | Escherichia coli | High-throughput screening | Identification | Biochemistry | Assaying | Antibacterial materials | Accumulation | Anticancer properties | E coli | Antibacterial activity | Cleavage | Deoxyribonucleic acid--DNA | Library collections | DNA topoisomerase (ATP-hydrolysing) | Enzymes | Fractionation | DNA topoisomerase | Antimicrobial agents | Screening | Chemistry | Inhibitors | Acids | Natural products | Mutation | Molecular biology | Cancer | Apoptosis | Index Medicus | Deoxyribonucleic acid | DNA
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Journal Article