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Pediatrics, ISSN 0031-4005, 06/2014, Volume 133, Issue 6, pp. 1023 - 1030
BACKGROUND: We previously reported decreased transfusions and donor exposures in preterm infants randomized to Darbepoetin (Darbe) or erythropoietin (Epo)... 
Cognitive outcome | Darbepoetin | Erythropoietin | Prematurity | prematurity | BRAIN-INJURY | PREMATURE-INFANTS | THRESHOLDS | TRIAL | GRAMS | BIRTH-WEIGHT INFANTS | cognitive outcome | CHILDREN BORN | PEDIATRICS | DEFICITS | darbepoetin | erythropoietin | TRANSFUSION REQUIREMENTS | WORKING-MEMORY | Concept Formation - drug effects | Developmental Disabilities - drug therapy | Prospective Studies | Follow-Up Studies | Erythropoietin - therapeutic use | Humans | Infant | Male | Dose-Response Relationship, Drug | Erythropoietin - analogs & derivatives | Blood Transfusion | Injections, Subcutaneous | Female | Developmental Disabilities - diagnosis | Infant, Newborn | Problem Solving - drug effects | Infant, Premature, Diseases - psychology | Double-Blind Method | Drug Administration Schedule | Infant, Premature, Diseases - diagnosis | Memory, Short-Term - drug effects | Cognition - drug effects | Infant, Premature, Diseases - drug therapy | Neuropsychological Tests | Neurologic Examination - drug effects | Darbepoetin alfa | Developmental Disabilities - psychology | Complications and side effects | Usage | Clinical trials | Research | Cognition disorders | Risk factors | Babies | Blood transfusions | Pediatrics | Neurosciences | Cognition & reasoning | Clinical outcomes | Placebo effect | Index Medicus | Abridged Index Medicus | 15.00 | 23.00 | 23.03
Journal Article
Amino Acids, ISSN 0939-4451, 9/2015, Volume 47, Issue 9, pp. 1893 - 1908
Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide (NO) synthesis, whereas l-arginine (Arg) and l-homoarginine (hArg) serve as... 
Biochemistry, general | N G -Methyltransferases | Homoarginine | Neurobiology | ADMA | Life Sciences | Analytical Chemistry | Life Sciences, general | Arginine | Biochemical Engineering | Proteomics | Knockout mouse | SAM | Methyltransferases | RAT-LIVER | LIVER AMIDINOTRANSFERASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEART-FAILURE | SYMMETRIC DIMETHYLARGININE | CREATINE | SUBSTRATE-SPECIFICITY | PLASMA | GLYCINE AMIDINOTRANSFERASE | NITRIC-OXIDE | N-G-Methyltransferases | CARDIOVASCULAR RISK | Developmental Disabilities - blood | Developmental Disabilities - drug therapy | Language Development Disorders - blood | Language Development Disorders - drug therapy | Speech Disorders - drug therapy | Guanidinoacetate N-Methyltransferase - genetics | Humans | Middle Aged | Amidinotransferases - genetics | Male | Developmental Disabilities - genetics | Coronary Artery Disease - blood | Arginine - analogs & derivatives | Arginine - administration & dosage | Intellectual Disability - genetics | Intellectual Disability - blood | Amino Acid Metabolism, Inborn Errors - genetics | Peripheral Arterial Disease - genetics | Amidinotransferases - blood | Peripheral Arterial Disease - blood | Adult | Female | Child | Guanidinoacetate N-Methyltransferase - blood | Speech Disorders - blood | Amidinotransferases - deficiency | Language Development Disorders - genetics | Peripheral Arterial Disease - drug therapy | Speech Disorders - genetics | Coronary Artery Disease - drug therapy | Guanidinoacetate N-Methyltransferase - metabolism | Movement Disorders - blood | Amidinotransferases - metabolism | Amino Acid Metabolism, Inborn Errors - blood | Mice, Knockout | Intellectual Disability - drug therapy | Animals | Homoarginine - biosynthesis | Arginine - biosynthesis | Guanidinoacetate N-Methyltransferase - deficiency | Movement Disorders - congenital | Adolescent | Coronary Artery Disease - genetics | Mice | Movement Disorders - genetics | Amino Acid Metabolism, Inborn Errors - drug therapy | Movement Disorders - drug therapy | Analysis | Nitric oxide | Transferases | Resveratrol | Physiological aspects | Biosynthesis | Chemical properties | Methylation | Index Medicus | Human | Proteins | Synthesis | Asymmetry | Coronary artery disease | Patients | Ingestion
Journal Article
Journal of Autism and Developmental Disorders, ISSN 0162-3257, 6/2016, Volume 46, Issue 6, pp. 1887 - 1894
This study describes antipsychotic use and metabolic monitoring rates among individuals with developmental disabilities enrolled in a subspecialty medical home... 
Pediatrics | Antipsychotics | Child and School Psychology | Neurosciences | Public Health | Intellectual disability | Medical home | Psychology | Autism spectrum disorder | AUTISM | QUALITY | PSYCHOLOGY, DEVELOPMENTAL | ADULTS | RISK | PREVALENCE | CHILDREN | NONFASTING TRIGLYCERIDES | WEIGHT-GAIN | PEOPLE | Hypertension | Developmental Disabilities | Gender Differences | Autism | Nursing Homes | Age Differences | Pervasive Developmental Disorders | Drug Therapy | Diabetes | Metabolism | Intellectual Disability | Drug Use | Developmental Disabilities - drug therapy | Developmental Disabilities - metabolism | United States | Humans | Middle Aged | Patient-Centered Care | Autism Spectrum Disorder - complications | Body Weight - drug effects | Child, Preschool | Intellectual Disability - complications | Male | Intellectual Disability - metabolism | Young Adult | Antipsychotic Agents - therapeutic use | Lipids - blood | Aged, 80 and over | Adult | Female | Medicaid | Child | Intellectual Disability - drug therapy | Autism Spectrum Disorder - metabolism | Adolescent | Sex Factors | Aged | Antipsychotic Agents - pharmacology | Autism Spectrum Disorder - drug therapy | Developmental Disabilities - complications | Antipsychotic drugs | Analysis | Aging | Child development deviations | Dosage and administration | Research | Diagnosis | Drug therapy | Risk factors | Developmental disabilities | Developmentally disabled people | Neuroleptics | Intellectual disabilities | Metabolic control | Diabetes mellitus | Dyslipidemia | Autistic spectrum disorders | Lipid metabolism | Index Medicus
Journal Article
Journal Article
Journal Article
Journal Article
Pediatrics, ISSN 0031-4005, 08/2008, Volume 122, Issue 2, pp. 383 - 391
OBJECTIVES. High-dose recombinant erythropoietin is neuroprotective in animal models of neonatal brain injury. Extremely low birth weight infants are at high... 
Neuroprotection | Neonate | Preterm | RECOMBINANT-HUMAN-ERYTHROPOIETIN | PREMATURE-INFANTS | preterm | STEADY-STATE VOLUME | RECEPTOR | neonate | PRETERM INFANTS | BOUND IRON | NEONATAL-RATS | neuroprotection | IN-VIVO | PEDIATRICS | OUTCOMES | BRAIN | Single-Blind Method | Developmental Disabilities - drug therapy | Prospective Studies | Follow-Up Studies | Humans | Brain Diseases - mortality | Developmental Disabilities - prevention & control | Male | Reference Values | Infant, Premature, Diseases - mortality | Recombinant Proteins | Dose-Response Relationship, Drug | Brain Diseases - drug therapy | Female | Developmental Disabilities - mortality | Infant, Newborn | Infant, Extremely Low Birth Weight | Erythropoietin - administration & dosage | Infant, Premature, Diseases - prevention & control | Drug Administration Schedule | Risk Assessment | Treatment Outcome | Erythropoietin - pharmacokinetics | Gestational Age | Infant, Premature, Diseases - drug therapy | Brain Diseases - prevention & control | Analysis of Variance | Survival Analysis | Infusions, Intravenous | Pediatric pharmacology | Complications and side effects | Erythropoietin | Dosage and administration | Research | Birth weight, Low | Drug therapy | Babies | Clinical trials | Brain damage | Risk | Birth weight | Glycoproteins | Comparative analysis | Index Medicus | Abridged Index Medicus
Journal Article
Epilepsia, ISSN 0013-9580, 07/2018, Volume 59, Issue 7, pp. 1307 - 1315
ObjectiveWe analyzed long-term changes of lobar glucose metabolic abnormalities in relation to clinical seizure variables and development in a large group of... 
development | seizure frequency | positron emission tomography | pediatric epilepsy | follow‐up | follow-up | FDG-PET | SURGERY | CORTICAL DYSPLASIA | COMPLEX | CLINICAL NEUROLOGY | POSITRON-EMISSION-TOMOGRAPHY | SEIZURES | REORGANIZATION | HYPOMETABOLISM | INTRACTABLE EPILEPSY | CONSUMPTION | Brain - diagnostic imaging | Developmental Disabilities - drug therapy | Follow-Up Studies | Humans | Child, Preschool | Infant | Male | Drug Resistant Epilepsy - diagnostic imaging | Positron-Emission Tomography | Drug Resistant Epilepsy - drug therapy | Developmental Disabilities - diagnostic imaging | Dominance, Cerebral - physiology | Female | Retrospective Studies | Dominance, Cerebral - drug effects | Energy Metabolism - physiology | Child | Developmental Disabilities - physiopathology | Brain - physiopathology | Anticonvulsants - therapeutic use | Disease Progression | Brain - drug effects | Magnetic Resonance Imaging | Electroencephalography - drug effects | Adolescent | Fluorodeoxyglucose F18 | Blood Glucose - metabolism | Drug Resistant Epilepsy - physiopathology | Energy Metabolism - drug effects | Glucose metabolism | Analysis | Epilepsy | Physiological aspects | Seizures (Medicine) | Glucose | Children | Drug resistance | Drug therapy | Dextrose | Neurological diseases | Surgery | Cognition | Metabolism | Positron emission tomography | Seizures | Index Medicus
Journal Article
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, ISSN 1552-4868, 06/2015, Volume 169, Issue 2, pp. 150 - 157
Journal Article
Molecular Genetics and Metabolism, ISSN 1096-7192, 12/2015, Volume 116, Issue 4, pp. 252 - 259
Arginine:glycine aminotransferase (AGAT) ( ) deficiency is an autosomal recessive inborn error of creative synthesis. We performed an international survey... 
GATM | Cerebral creatine deficiency | Intellectual disability | Myopathy | MEDICINE, RESEARCH & EXPERIMENTAL | INBORN ERROR | METABOLISM | HOMOARGININE | ARGININE/GLYCINE AMIDINOTRANSFERASE | DISEASE | ENDOCRINOLOGY & METABOLISM | GENETICS & HEREDITY | CREATINE DEFICIENCY | BRAIN | Glycine - analogs & derivatives | Developmental Disabilities - drug therapy | Speech Disorders - drug therapy | Amino Acid Metabolism, Inborn Errors - physiopathology | Glycine - urine | Humans | Child, Preschool | Amidinotransferases - genetics | Male | Developmental Disabilities - genetics | Intellectual Disability - genetics | Amino Acid Metabolism, Inborn Errors - diagnosis | Young Adult | Amino Acid Metabolism, Inborn Errors - genetics | Muscular Diseases - physiopathology | Muscular Diseases - drug therapy | Glycine - deficiency | Creatine - deficiency | Female | Amidinotransferases - chemistry | Child | Developmental Disabilities - diagnosis | Speech Disorders - diagnosis | Protein Structure, Tertiary | Developmental Disabilities - physiopathology | Glycine - blood | Amidinotransferases - deficiency | Gene Expression | Magnetic Resonance Spectroscopy | Protein Structure, Secondary | Speech Disorders - genetics | Models, Molecular | Treatment Outcome | Genes, Recessive | Sequence Analysis, DNA | Speech Disorders - physiopathology | Intellectual Disability - drug therapy | Intellectual Disability - physiopathology | Muscular Diseases - diagnosis | Intellectual Disability - diagnosis | Adolescent | Creatine - therapeutic use | Muscular Diseases - genetics | Mutation | Amino Acid Metabolism, Inborn Errors - drug therapy | Arginine | Glycine | Index Medicus
Journal Article
Pediatrics, ISSN 0031-4005, 08/2008, Volume 122, Issue 2, pp. 375 - 382