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Journal Article
Journal Article
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 02/2018, Volume 58, Issue 2, pp. 180 - 192
...%. This multiarm phase 1 study (Clinicaltrials.gov identifier: NCT01454076) investigated the effect of the strong CYP3A inhibitors ketoconazole and clarithromycin and the strong CYP3A inducer rifampin on the pharmacokinetics of ixazomib. Eighty... 
pharmacokinetics | CYP3A | multiple myeloma | drug‐drug interaction | PBPK modeling | ixazomib | drug-drug interaction | CLARITHROMYCIN | DEXAMETHASONE | SAFETY | RIFAMPIN | RELAPSED/REFRACTORY MULTIPLE-MYELOMA | P-GLYCOPROTEIN | PHASE-1 | LENALIDOMIDE | CYTOCHROME-P450 3A ACTIVITY | PHARMACOLOGY & PHARMACY | MIDAZOLAM | Glycine - pharmacokinetics | Neoplasms - metabolism | Glycine - analogs & derivatives | Cytochrome P-450 CYP3A Inhibitors - pharmacology | Administration, Oral | Humans | Middle Aged | Boron Compounds - pharmacokinetics | Male | Ketoconazole - pharmacology | Cytochrome P-450 CYP3A Inducers - pharmacology | Drug Interactions | Cytochrome P-450 CYP3A - metabolism | Models, Biological | Aged, 80 and over | Adult | Female | Aged | Antineoplastic Agents - pharmacokinetics | Rifampin - pharmacology | Clarithromycin - pharmacology | Proteasome Inhibitors - pharmacokinetics | Care and treatment | Lymphomas | Pharmacokinetics | Analysis | Cytochrome | Clarithromycin | Ketoconazole | Toxicity | Cytochrome P450 | Drug interactions | Pharmacology | Glycoproteins | Metabolism | Patients | Lymphoma | Studies | Intestine | Isoforms | Least squares | Drug interaction | Solid tumors | P-Glycoprotein | Rifampin | Inducers | Tumors | Index Medicus
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 04/2019, Volume 299, pp. 53 - 63
Journal Article
Investigational new drugs, ISSN 1573-0646, 2017, Volume 36, Issue 3, pp. 407 - 415
Journal Article
British journal of haematology, ISSN 0007-1048, 2016, Volume 174, Issue 5, pp. 748 - 759
Journal Article