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Canadian Journal of Anesthesia / Journal canadien d'anesthesie, ISSN 0832-610X, 07/2019, Volume 66, Issue 7, p. 751
Journal Article
Clinical Pharmacokinetics, ISSN 0312-5963, 8/2017, Volume 56, Issue 8, pp. 893 - 913
Dexmedetomidine is an α2-adrenoceptor agonist with sedative, anxiolytic, sympatholytic, and analgesic-sparing effects, and minimal depression of respiratory... 
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | ISCHEMIA-REPERFUSION INJURY | MINIMUM ALVEOLAR CONCENTRATION | INCREASING PLASMA-CONCENTRATIONS | POPULATION PHARMACOKINETICS | INTRAVENOUS DEXMEDETOMIDINE | INTRANASAL DEXMEDETOMIDINE | DOUBLE-BLIND | BRACHIAL-PLEXUS BLOCK | PHARMACOLOGY & PHARMACY | INTRAMUSCULAR DEXMEDETOMIDINE | INTENSIVE-CARE | Cardiac Output - physiology | Pediatrics | Intensive Care Units - standards | Analgesics, Non-Narcotic - pharmacokinetics | Hypnotics and Sedatives - adverse effects | Adrenergic alpha-2 Receptor Agonists - pharmacokinetics | Humans | Hypnotics and Sedatives - administration & dosage | Male | Administration, Buccal | Adrenergic alpha-2 Receptor Agonists - administration & dosage | Adrenergic alpha-2 Receptor Agonists - adverse effects | Analgesics, Non-Narcotic - adverse effects | Hypertension - chemically induced | Adult | Anesthesia | Female | Receptors, GABA - drug effects | Body Mass Index | Dexmedetomidine - administration & dosage | Hypnotics and Sedatives - pharmacokinetics | Dexmedetomidine - pharmacokinetics | Analgesics, Non-Narcotic - administration & dosage | Hypotension - chemically induced | Administration, Intranasal | Dexmedetomidine - adverse effects | Bradycardia - chemically induced | Serum Albumin, Human - physiology | Liver - physiology | Hemodynamics - drug effects | Infusions, Intravenous | Care and treatment | Analysis | Depression, Mental | Dexmedetomidine | Pharmacology | Dosage and administration | Pharmacokinetics | Systematic review | Kinases | Rodents | Review
Journal Article
Current Pharmaceutical Design, ISSN 1381-6128, 2012, Volume 18, Issue 38, pp. 6257 - 6265
The alpha-2 agonist dexmedetomidine is being increasingly used for sedation and as an adjunctive agent during general and regional anesthesia. It is used in a... 
Anesthesia | Surgery | Dexmedetomidine | dexmedetomidine | ALPHA-AGONIST DEXMEDETOMIDINE | INTRAVENOUS REGIONAL ANESTHESIA | RANDOMIZED CONTROLLED-TRIAL | ALPHA-ADRENOCEPTOR AGONIST DEXMEDETOMIDINE | CARBON-DIOXIDE RESPONSE | CARDIAC-SURGERY | PHARMACOLOGY & PHARMACY | AWAKE FIBEROPTIC INTUBATION | LONG-TERM SEDATION | CEREBRAL-BLOOD-FLOW | CRITICALLY-ILL PATIENTS | surgery | Critical Care - methods | Neuroprotective Agents - therapeutic use | Anesthesia - methods | Hypnotics and Sedatives - adverse effects | Adrenergic alpha-2 Receptor Agonists - pharmacokinetics | Humans | Hypnotics and Sedatives - administration & dosage | Critical Illness | Hypnotics and Sedatives - therapeutic use | Adrenergic alpha-2 Receptor Agonists - administration & dosage | Adrenergic alpha-2 Receptor Agonists - therapeutic use | Drug Interactions | Hypotension - physiopathology | Neuroprotective Agents - pharmacokinetics | Adrenergic alpha-2 Receptor Agonists - adverse effects | Neuroprotective Agents - adverse effects | Neuroprotective Agents - administration & dosage | Dexmedetomidine - administration & dosage | Drug Administration Routes | Dexmedetomidine - therapeutic use | Hypnotics and Sedatives - pharmacokinetics | Cerebrovascular Circulation - drug effects | Dexmedetomidine - pharmacokinetics | Bradycardia - physiopathology | Endoscopy, Gastrointestinal | Anesthesia - adverse effects | Hypotension - chemically induced | Dexmedetomidine - adverse effects | Bradycardia - chemically induced | Animals
Journal Article
11/2011
Intravenous administration of benzodiazepines can be used for anxiety management in dentistry. The recent approval of Dexmedetomidine in Canada provides an... 
0567 | Dexmedetomidine | Sedation
Dissertation