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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2014, Volume 111, Issue 17, pp. 6305 - 6310
Journal Article
Pituitary, ISSN 1386-341X, 10/2017, Volume 20, Issue 5, pp. 594 - 601
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1411 - 11
Congenital nephrogenic diabetes insipidus (NDI) is characterized by the inability of the kidney to concentrate urine. Congenital NDI is mainly caused by... 
SPECIFICITY | PHOSPHORYLATION | PROTEIN-KINASE | REGULATORY SUBUNITS | MEMBRANE | MULTIDISCIPLINARY SCIENCES | AQUAPORIN-2 WATER CHANNEL | COMBINATION | EXPRESSION | DUCT PRINCIPAL CELLS | ANCHORING PROTEIN | Epithelial Cells - metabolism | Aquaporin 2 - agonists | Epithelial Cells - drug effects | Humans | Receptors, Vasopressin - metabolism | Male | A Kinase Anchor Proteins - genetics | Diabetes Insipidus, Nephrogenic - drug therapy | Cyclic AMP-Dependent Protein Kinases - genetics | Osmolar Concentration | Diabetes Insipidus, Nephrogenic - genetics | Protein Binding - drug effects | Cyclic AMP - metabolism | A Kinase Anchor Proteins - metabolism | Disease Models, Animal | Phenols - pharmacology | Cyclic AMP-Dependent Protein Kinases - metabolism | Kidney Tubules, Collecting - drug effects | Amino Acid Sequence | A Kinase Anchor Proteins - antagonists & inhibitors | Arginine Vasopressin | Mice, Inbred C57BL | Gene Expression Regulation | Water - metabolism | Kidney Tubules, Collecting - pathology | Epithelial Cells - pathology | Benzazepines - pharmacology | Diabetes Insipidus, Nephrogenic - pathology | Aquaporin 2 - metabolism | Kidney Tubules, Collecting - metabolism | Benzazepines - antagonists & inhibitors | Animals | Receptors, Vasopressin - genetics | Benzhydryl Compounds - pharmacology | Aquaporin 2 - genetics | Cell Line, Transformed | Diabetes Insipidus, Nephrogenic - metabolism | Protein kinase A | Water treatment | Nondestructive testing | Diabetes insipidus | Chaperones | Kinases | Molecular weight | Odorant receptors | Proteins | Low molecular weights | Inhibition | Vomeronasal organ | Aquaporin 2 | Anchoring | Vasopressin V2 receptors | Urine | Adenosine monophosphate | Channel gating | Diabetes mellitus | Cyclic AMP | Inspection | Vasopressin | Sodium | Diabetes | Mutation | Collecting duct
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2011, Volume 108, Issue 31, pp. 12949 - 12954
In the kidney, the actions of vasopressin on its type-2 receptor (V2R) induce increased water reabsorption alongside polyphosphorylation and membrane targeting... 
Urine | Receptors | Phosphorylation | Prostaglandins | Kidneys | Nondestructive testing | Nephrogenic diabetes insipidus | Agonists | Cell membranes | Kidney cells | Drug development/discovery | Water balance | Autocoid | Lipid mediators | Cell signaling | RENAL EPITHELIAL-CELLS | LOCALIZATION | drug development/discovery | PHOSPHORYLATION | SUBTYPES | MULTIDISCIPLINARY SCIENCES | MEMBRANE INSERTION | RATS | water balance | PLASMA-MEMBRANE | lipid mediators | COLLECTING DUCT | EP4 RECEPTOR | cell signaling | autocoid | WATER | Rats, Wistar | Receptors, Prostaglandin E, EP2 Subtype - metabolism | Receptors, Vasopressin - metabolism | Immunoblotting | Male | Vasopressins - metabolism | Protein Transport - drug effects | Alprostadil - analogs & derivatives | Dose-Response Relationship, Drug | Kidney - metabolism | Diabetes Insipidus, Nephrogenic - genetics | Pyrrolidinones - pharmacology | Cell Membrane - metabolism | Diabetes Insipidus, Nephrogenic - prevention & control | Phosphorylation - drug effects | Cyclic AMP - metabolism | Cell Membrane - drug effects | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Receptors, Prostaglandin E, EP4 Subtype - agonists | Receptors, Prostaglandin E, EP4 Subtype - genetics | Cell Line | Dinoprostone - pharmacology | Kidney - drug effects | Receptors, Prostaglandin E, EP2 Subtype - genetics | Alprostadil - pharmacology | Rats | Vasopressins - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Aquaporin 2 - metabolism | Microscopy, Confocal | Animals | Dogs | Receptors, Vasopressin - genetics | Dinoprostone - analogs & derivatives | Antidiuretic Hormone Receptor Antagonists | Aquaporin 2 - genetics | Receptors, Prostaglandin E, EP2 Subtype - agonists | Diabetes Insipidus, Nephrogenic - metabolism | Aquaporins | Diabetes insipidus | Physiological aspects | Development and progression | Health aspects | Vasopressin | Agonists (Biochemistry) | Biological Sciences | discovery | drug development
Journal Article