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Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 2000, Volume 67, Issue 5, pp. 1174 - 1185
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 2000, Volume 67, Issue 5, pp. 1186 - 1200
Journal Article
Nature, ISSN 0028-0836, 04/2012, Volume 484, Issue 7394, pp. 333 - 338
The prevalence of obesity and type 2 diabetes is increasing worldwide and threatens to shorten lifespan. Impaired insulin action in peripheral tissues is a... 
DIABETES-MELLITUS | FATTY-ACID SYNTHESIS | GENE | INSULIN-RESISTANCE | LIPOGENESIS | MULTIDISCIPLINARY SCIENCES | CARBOHYDRATE-RESPONSE ELEMENT | LIVER | BINDING-PROTEIN CHREBP | UCSC GENOME BROWSER | TRANSGENIC MICE | Transcription Factors - chemistry | Diabetes Mellitus - genetics | Humans | Male | RNA, Messenger - metabolism | Adipose Tissue - metabolism | Protein Isoforms - chemistry | Nuclear Proteins - deficiency | Lipogenesis | Body Mass Index | Glucose Transporter Type 4 - genetics | Adipose Tissue - pathology | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - chemistry | Genotype | Glucose - pharmacology | Nuclear Proteins - chemistry | Mice, Knockout | Insulin - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Insulin Resistance - genetics | Glucose - metabolism | Mice | Blood Glucose - metabolism | Homeostasis - genetics | Cohort Studies | Diabetes Mellitus - blood | Body Weight | Glucose Transporter Type 4 - metabolism | Transcription Factors - deficiency | Adipose Tissue - cytology | Molecular Sequence Data | Obesity - genetics | Promoter Regions, Genetic - genetics | Protein Isoforms - metabolism | Adiposity | Female | Nuclear Proteins - genetics | Insulin - pharmacology | Glucose Intolerance - genetics | Cross-Sectional Studies | Gene Expression Regulation - genetics | RNA, Messenger - genetics | Cells, Cultured | Diabetes Mellitus - metabolism | Nuclear Proteins - metabolism | Transcription Factors - genetics | Obesity - metabolism | Transcription Factors - metabolism | Animals | Glucose Transporter Type 4 - biosynthesis | Adipocytes - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Protein Isoforms - genetics | Index Medicus
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2006, Volume 355, Issue 5, pp. 456 - 466
In this study, mutations in the gene encoding the sulfonylurea receptor, a component of the beta-cell ATP-sensitive potassium channel, are described in infants... 
IMMUNE DYSREGULATION | KIR6.2 MUTATIONS | NUCLEOTIDES | REGULATOR | MEDICINE, GENERAL & INTERNAL | MECHANISM | K-ATP CHANNELS | INSULIN-SECRETION | STOICHIOMETRY | SULFONYLUREA RECEPTOR | TRANSIENT | Tolbutamide - pharmacology | Diabetes Complications | Diabetes Mellitus - genetics | Receptors, Drug - genetics | Humans | Male | Mutation, Missense | Sulfonylurea Receptors | Potassium Channels - metabolism | Insulin-Secreting Cells - metabolism | ATP-Binding Cassette Transporters - genetics | ATP-Binding Cassette Transporters - metabolism | Female | Potassium Channels, Inwardly Rectifying - antagonists & inhibitors | Infant, Newborn | Hypoglycemic Agents - therapeutic use | Sulfonylurea Compounds - therapeutic use | Diabetes Mellitus - drug therapy | Diabetes Mellitus - metabolism | Potassium Channels, Inwardly Rectifying - genetics | Receptors, Drug - metabolism | Potassium Channels - genetics | Birth Weight | Insulin-Secreting Cells - drug effects | Pedigree | Heterozygote | Developmental Disabilities - complications | Potassium Channels, Inwardly Rectifying - metabolism | Receptors, Drug - antagonists & inhibitors | ATP-Binding Cassette Transporters - antagonists & inhibitors | Infants (Newborn) | Genetic aspects | Diabetes | Research | Gene mutations | Diseases | Mutation | Pancreas | Genes | Adenosine triphosphatase | Index Medicus | Abridged Index Medicus | Life Sciences | Genetics | Human genetics
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, pp. e54442 - e54442
Sodium/glucose cotransporter 2 (SGLT2) inhibitors are oral hypoglycemic agents used to treat patients with diabetes mellitus. SGLT2 inhibitors block... 
MATRIX | STIMULATION | MULTIDISCIPLINARY SCIENCES | DISEASE | HIGH GLUCOSE | GENE-EXPRESSION | MESANGIAL CELLS | PPAR-GAMMA AGONISTS | MELLITUS | TRANSFORMING GROWTH FACTOR-BETA | Diabetes Mellitus - pathology | Epithelial Cells - metabolism | Gene Expression - drug effects | Diabetes Mellitus - genetics | Transcription Factor AP-1 - genetics | Epithelial Cells - drug effects | Humans | Diabetic Nephropathies - drug therapy | NF-kappa B - metabolism | Smad3 Protein - metabolism | Transcription Factor AP-1 - metabolism | Sodium-Glucose Transporter 1 - genetics | Smad3 Protein - genetics | Sodium-Glucose Transporter 1 - metabolism | Phosphorylation - drug effects | Interleukin-6 - metabolism | Transforming Growth Factor beta1 - pharmacology | Sodium-Glucose Transporter 2 - genetics | Collagen Type IV - metabolism | Sodium-Glucose Transporter 1 - antagonists & inhibitors | Promoter Regions, Genetic | Diabetic Nephropathies - pathology | Glucosides - pharmacology | Kidney Tubules, Proximal - pathology | Interleukin-6 - genetics | Sodium-Glucose Transporter 2 - metabolism | Diabetic Nephropathies - metabolism | Diabetes Mellitus - drug therapy | Diabetes Mellitus - metabolism | Toll-Like Receptor 4 - genetics | Diabetic Nephropathies - genetics | Epithelial Cells - pathology | Glucose - pharmacology | Toll-Like Receptor 4 - metabolism | Sodium-Glucose Transporter 2 - antagonists & inhibitors | Hypoglycemic Agents - pharmacology | NF-kappa B - genetics | Kidney Tubules, Proximal - metabolism | Collagen Type IV - genetics | Protein Binding | Benzhydryl Compounds - pharmacology | Kidney Tubules, Proximal - drug effects | Physiological aspects | Care and treatment | Genetic aspects | Research | Transforming growth factors | Diabetic nephropathies | Chromatin | Immunoprecipitation | Transforming growth factor-b | Interleukin | Clinical trials | Systematic review | Smad3 protein | Glucose | Kinases | Interleukin 6 | Proteins | Hyperglycemia | Rodents | Collagen (type IV) | Hypoglycemic agents | Inhibition | Growth factors | Deoxyribonucleic acid--DNA | Binding | Glucose transporter | Medical research | NF-κB protein | Secretion | Diabetes mellitus | Markers | Activator protein 1 | Blocking | Reabsorption | Inflammation | Gene expression | Glucose transport | Immune systems | Medicine | High mobility group proteins | Hospitals | Inhibitors | Nephropathy | Sodium |