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Journal Article
Nature Medicine, ISSN 1078-8956, 08/2009, Volume 15, Issue 8, pp. 940 - 945
Journal Article
Circulation, ISSN 0009-7322, 10/2017, Volume 136, Issue 17, pp. 1629 - 1642
Journal Article
Kidney International, ISSN 0085-2538, 08/2011, Volume 80, Issue 4, pp. 358 - 368
Enhanced transforming growth factor-β1 (TGF-β1) expression in renal cells promotes fibrosis and hypertrophy during the progression of diabetic nephropathy. The... 
TGF-β | fibrosis | diabetic nephropathy | gene expression | cell signaling | Up-Regulation | Diabetes Mellitus, Type 2 - genetics | Homeodomain Proteins - metabolism | Transforming Growth Factor beta1 - metabolism | Diabetes Mellitus, Experimental - genetics | Diabetes Mellitus, Type 1 - metabolism | Homeostasis | MicroRNAs - metabolism | Diabetes Mellitus, Type 2 - metabolism | Transfection | Time Factors | Kruppel-Like Transcription Factors - metabolism | Upstream Stimulatory Factors - metabolism | Diabetes Mellitus, Type 1 - chemically induced | Diabetes Mellitus, Experimental - chemically induced | 3' Untranslated Regions | Diabetes Mellitus, Experimental - metabolism | Binding Sites | Collagen Type IV - metabolism | Promoter Regions, Genetic | Diabetic Nephropathies - pathology | Collagen Type I - metabolism | Diabetic Nephropathies - metabolism | Cells, Cultured | Diabetes Mellitus, Type 1 - pathology | Diabetes Mellitus, Type 1 - genetics | Diabetic Nephropathies - genetics | Transforming Growth Factor beta1 - genetics | Mesangial Cells - metabolism | Oligonucleotides - metabolism | Animals | Fibrosis | Diabetes Mellitus, Experimental - pathology | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Mice | Diabetes Mellitus, Type 2 - pathology | Mutation | Zinc Finger E-box-Binding Homeobox 1 | Index Medicus
Journal Article
Circulation, ISSN 0009-7322, 01/2011, Volume 123, Issue 3, pp. 282 - 291
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2014, Volume 74, pp. 139 - 150
Abstract Exosomes, nano-vesicles naturally released from living cells, have been well recognized to play critical roles in mediating cell-to-cell... 
Cardiovascular | Type 2 diabetes | Cardiomyocytes | Exosomes | miR-320 | Myocardial angiogenesis | MiR-320 | CARDIAC & CARDIOVASCULAR SYSTEMS | HYPERGLYCEMIA | DYSFUNCTION | EXPRESSION | MICRORNA-320 | CELL BIOLOGY | Exosomes - drug effects | Exosomes - metabolism | Cell Proliferation | Rats, Wistar | Coculture Techniques | Diabetes Mellitus, Type 2 - genetics | Humans | Diabetes Mellitus, Experimental - genetics | Exosomes - pathology | HSP20 Heat-Shock Proteins - genetics | MicroRNAs - metabolism | Insulin-Like Growth Factor I - genetics | Diabetes Mellitus, Type 2 - metabolism | HSP20 Heat-Shock Proteins - metabolism | Biological Transport | Proto-Oncogene Protein c-ets-2 - genetics | Proto-Oncogene Protein c-ets-2 - metabolism | Diabetes Mellitus, Experimental - metabolism | Biomarkers - metabolism | Aniline Compounds - pharmacology | Signal Transduction | Endothelial Cells - metabolism | Gene Expression Regulation | Rats | Myocytes, Cardiac - pathology | Animals | Benzylidene Compounds - pharmacology | Myocytes, Cardiac - drug effects | Diabetes Mellitus, Experimental - pathology | Myocytes, Cardiac - metabolism | MicroRNAs - genetics | Diabetes Mellitus, Type 2 - pathology | Endothelial Cells - pathology | Insulin-Like Growth Factor I - metabolism | Neovascularization, Physiologic | Cell Movement | Endothelial Cells - drug effects | Antimitotic agents | Heat shock proteins | Diabetes | Antineoplastic agents | Heart cells | Endothelium | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2012, Volume 7, Issue 12, pp. e52013 - e52013
Objectives: Diabetic cardiomyopathy (DCM), characterized by myocardial structural and functional changes, is an independent cardiomyopathy that develops in... 
FIBROSIS | CELLS | OXIDATIVE STRESS | MULTIDISCIPLINARY SCIENCES | HEART-FAILURE | GENE-EXPRESSION | CARDIAC DYSFUNCTION | PPAR-GAMMA | RECEPTOR | GLYCATION END-PRODUCTS | DIASTOLIC DYSFUNCTION | Inflammation - pathology | Diabetes Mellitus, Experimental - drug therapy | Fibrosis - drug therapy | Diabetic Cardiomyopathies - metabolism | Diabetic Cardiomyopathies - drug therapy | Rats, Wistar | Apoptosis - drug effects | Diabetes Mellitus, Experimental - genetics | Apoptosis - genetics | Glycogen Synthase Kinase 3 beta | Male | Fibrosis - metabolism | Proto-Oncogene Proteins c-akt - genetics | Inflammation - metabolism | Cell Death - genetics | Ventricular Dysfunction, Left - genetics | Inflammation - drug therapy | Myocardium - metabolism | Ventricular Dysfunction, Left - pathology | Cell Death - drug effects | Phosphorylation - drug effects | Diabetes Mellitus, Experimental - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Receptor for Advanced Glycation End Products | Fibrosis - genetics | Curcumin - pharmacology | Oxidative Stress - genetics | Rats | Myocardium - pathology | Glycogen Synthase Kinase 3 - metabolism | Diabetic Cardiomyopathies - genetics | Ventricular Dysfunction, Left - metabolism | Animals | Ventricular Dysfunction, Left - drug therapy | Glycogen Synthase Kinase 3 - genetics | Diabetes Mellitus, Experimental - pathology | Heart - drug effects | Inflammation - genetics | Diabetic Cardiomyopathies - pathology | Fibrosis - pathology | Oxidative Stress - drug effects | Receptors, Immunologic - genetics | Receptors, Immunologic - metabolism | Oxidases | Heart | Biological products | Cardiomyopathy | Heart diseases | Enzyme-linked immunosorbent assay | Apoptosis | Oxidative stress | Phosphorylation | Bax protein | Bcl-2 protein | Science | AKT protein | Cardiovascular disease | Caspase-3 | NAD(P)H oxidase | Accumulation | Proteins | Signal transduction | Hyperglycemia | Ultrastructure | Biochemical tests | Curcumin | Age | Energy intake | Stresses | Enzymes | Advanced glycosylation end products | Echocardiography | Abnormalities | Diabetes mellitus | Caspase | Rac1 protein | Pharmacology | Inflammation | Glycosylation | IL-1β | Gene expression | Metabolism | Stress | Studies | Signaling | Cell death | Fibrosis | Diabetes | Aberration | Laboratory animals | Metabolic disorders | Hypertrophy | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2012, Volume 109, Issue 39, pp. 15888 - 15893
The epidemics of insulin resistance (IR) and type 2 diabetes (T2D) affect the first world as well as less-developed countries, and now affect children as well.... 
Receptors | 3T3 L1 cells | Myasthenia gravis | Diet | Insulin resistance | Mice | Adipocytes | Type 2 diabetes mellitus | Diabetes | Insulin | Aging | Glycotoxins | Obesity | LIFE-SPAN | OXIDATIVE STRESS | METABOLIC SYNDROME | OXIDANT STRESS | MULTIDISCIPLINARY SCIENCES | DOWN-REGULATION | RISK-FACTOR | glycotoxins | MESANGIAL CELLS | aging | INFLAMMATORY RESPONSE | END-PRODUCTS | obesity | METHYLGLYOXAL | Sirtuin 1 - metabolism | Deoxyglucose - metabolism | Diabetes Mellitus, Type 2 - genetics | Humans | Diabetes Mellitus, Experimental - genetics | Metabolic Syndrome - metabolism | Diabetes Mellitus, Type 2 - metabolism | Insulin Receptor Substrate Proteins - metabolism | Metabolic Syndrome - chemically induced | Sirtuin 1 - genetics | Inflammation - drug therapy | Glycation End Products, Advanced - adverse effects | Diabetes Mellitus, Experimental - metabolism | Insulin Receptor Substrate Proteins - genetics | Receptor for Advanced Glycation End Products | Macrophages - pathology | Administration, Oral | Oxidative Stress - genetics | 3T3-L1 Cells | Adipocytes - pathology | Proto-Oncogene Proteins c-akt | Macrophages - metabolism | Animals | Glycation End Products, Advanced - pharmacology | Metabolic Syndrome - genetics | Adipocytes - metabolism | Deoxyglucose - genetics | Diabetes Mellitus, Experimental - pathology | Inflammation - genetics | Diabetes Mellitus, Type 2 - pathology | Metabolic Syndrome - pathology | Oxidative Stress - drug effects | Receptors, Immunologic - genetics | Receptors, Immunologic - metabolism | Type 2 diabetes | Antioxidants | Cell receptors | Physiological aspects | Glycosylation | Properties | Proteins | Oxidative stress | Genotype & phenotype | Epidemics | Index Medicus | Biological Sciences
Journal Article