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diabetes-insulin-glucagon-gastrointestinal (97) 97
abridged index medicus (94) 94
animals (94) 94
endocrinology & metabolism (94) 94
index medicus (94) 94
mice (65) 65
male (61) 61
rats (32) 32
insulin - metabolism (30) 30
humans (29) 29
female (27) 27
mice, knockout (23) 23
mice, inbred c57bl (22) 22
glucose - metabolism (21) 21
hormones, hormone substitutes, and hormone antagonists (19) 19
cells, cultured (17) 17
liver - metabolism (15) 15
digestive, oral, and skin physiology (13) 13
expression (13) 13
resistance (13) 13
endocrine system (12) 12
mice, transgenic (12) 12
cell line (11) 11
insulin secretion (11) 11
signal transduction - drug effects (11) 11
gene-expression (10) 10
insulin resistance - physiology (10) 10
insulin-secreting cells - metabolism (10) 10
rats, wistar (10) 10
300 (9) 9
500 (9) 9
activation (9) 9
diabetes-mellitus (9) 9
gene expression regulation (9) 9
insulin - pharmacology (9) 9
insulin resistance (9) 9
islets of langerhans - metabolism (9) 9
obesity (9) 9
rats, sprague-dawley (9) 9
apoptosis (8) 8
blood glucose - metabolism (8) 8
calcium - metabolism (8) 8
homeostasis (8) 8
mouse (8) 8
oxidative stress (8) 8
rna, messenger - metabolism (8) 8
cells (7) 7
glucose (7) 7
in-vivo (7) 7
insulin-secreting cells - drug effects (7) 7
islets of langerhans - drug effects (7) 7
liver - drug effects (7) 7
receptor (7) 7
signal transduction (7) 7
3t3-l1 adipocytes (6) 6
adipose-tissue (6) 6
diet, high-fat - adverse effects (6) 6
diet-induced obesity (6) 6
digestive system (6) 6
fatty liver-disease (6) 6
gene expression regulation - drug effects (6) 6
glucose clamp technique (6) 6
hypoglycemic agents - pharmacology (6) 6
insulin (6) 6
insulin-resistance (6) 6
insulin-secreting cells - cytology (6) 6
muscle, skeletal - metabolism (6) 6
obesity - metabolism (6) 6
oxidative stress - drug effects (6) 6
proto-oncogene proteins c-akt - metabolism (6) 6
cell proliferation (5) 5
endoplasmic-reticulum stress (5) 5
glucose - pharmacology (5) 5
insulin sensitivity (5) 5
islets of langerhans - cytology (5) 5
metabolism (5) 5
models, biological (5) 5
muscle, skeletal - drug effects (5) 5
pancreatic beta-cells (5) 5
phosphorylation - drug effects (5) 5
pregnancy (5) 5
promoter regions, genetic (5) 5
reverse transcriptase polymerase chain reaction (5) 5
type-2 diabetes-mellitus (5) 5
adipocytes - metabolism (4) 4
adipose tissue - metabolism (4) 4
blotting, western (4) 4
body weight (4) 4
deficiency (4) 4
diabetes mellitus, experimental - metabolism (4) 4
diabetes mellitus, type 2 - metabolism (4) 4
differentiation (4) 4
eating - drug effects (4) 4
energy metabolism - drug effects (4) 4
forkhead transcription factors - genetics (4) 4
forkhead transcription factors - metabolism (4) 4
gene (4) 4
glucose intolerance - metabolism (4) 4
glucose tolerance test (4) 4
glucose transporter type 4 - metabolism (4) 4
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1. Full Text A Novel Experimental Strategy to Assess the Metabolic Effects of Selective Activation of a Gq-Coupled Receptor in Hepatocytes In Vivo
by Hua Li, Jian and Jain, Shalini and McMillin, Sara M and Cui, Yinghong and Gautam, Dinesh and Sakamoto, Wataru and Lu, Huiyan and Jou, William and McGuinness, Owen P and Gavrilova, Oksana and Wess, Jürgen
Endocrinology, ISSN 0013-7227, 10/2013, Volume 154, Issue 10, pp. 3539 - 3551
Increased hepatic glucose production is a key pathophysiological feature of type 2 diabetes. Like all other cell types, hepatocytes express many G... 
Diabetes-Insulin-Glucagon-Gastrointestinal
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2. Full Text Overlap of Endocrine Hormone Expression in the Mouse Intestine Revealed by Transcriptional Profiling and Flow Cytometry
by Habib, Abdella M and Richards, Paul and Cairns, Lynne S and Rogers, Gareth J and Bannon, Christopher A. M and Parker, Helen E and Morley, Tom C. E and Yeo, Giles S. H and Reimann, Frank and Gribble, Fiona M
Endocrinology, ISSN 0013-7227, 07/2012, Volume 153, Issue 7, pp. 3054 - 3065
The intestine secretes a range of hormones with important local and distant actions, including the control of insulin secretion and appetite. A number of... 
GLP-1 | GLUCAGON-LIKE PEPTIDE-1 | GLUCOSE | GASTROINTESTINAL-TRACT | ENTEROENDOCRINE CELLS | LINE | ENDOCRINOLOGY & METABOLISM | PANCREATIC BETA-CELLS | DEPENDENT INSULINOTROPIC POLYPEPTIDE | DIFFERENTIATION | GIP | Flow Cytometry - methods | Oligonucleotide Array Sequence Analysis | Peptides - chemistry | Cell Separation | Mice, Inbred C57BL | Gene Expression Profiling | Intestines - metabolism | Enteroendocrine Cells - cytology | Transcription Factors - metabolism | Cholecystokinin - metabolism | Animals | Models, Biological | Transcription, Genetic | Chromogranin A - metabolism | Mice | Intestine, Small - metabolism | Intestines - cytology | Diabetes-Insulin-Glucagon-Gastrointestinal
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3. Full Text The Role of Bile After Roux-en-Y Gastric Bypass in Promoting Weight Loss and Improving Glycaemic Control
by Pournaras, Dimitri J and Glicksman, Clare and Vincent, Royce P and Kuganolipava, Shophia and Alaghband-Zadeh, Jamie and Mahon, David and Bekker, Jan H.R and Ghatei, Mohammad A and Bloom, Stephen R and Walters, Julian R.F and Welbourn, Richard and le Roux, Carel W
Endocrinology, ISSN 0013-7227, 08/2012, Volume 153, Issue 8, pp. 3613 - 3619
Gastric bypass leads to the remission of type 2 diabetes independently of weight loss. Our hypothesis is that changes in bile flow due to the altered anatomy... 
PEPTIDE-YY | GUT HORMONES | ENERGY-EXPENDITURE | OBESE SUBJECTS | THERAPY | GLUCOSE-METABOLISM | ACIDS | ENDOCRINOLOGY & METABOLISM | FARNESOID-X-RECEPTOR | BARIATRIC SURGERY | TYPE-2 DIABETES-MELLITUS | Gastric Bypass | Bile Acids and Salts - blood | C-Reactive Protein | Rats, Wistar | Humans | Middle Aged | Bile - physiology | Rats | Glucagon-Like Peptide 1 - blood | Male | Animals | Fibroblast Growth Factors - blood | Dogs | Weight Loss - physiology | Adult | Calorimetry | Female | Peptide YY - blood | Diabetes Mellitus, Type 2 | Blood Glucose - metabolism | Diabetes-Insulin-Glucagon-Gastrointestinal
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4. Full Text Bile Acids Trigger GLP-1 Release Predominantly by Accessing Basolaterally Located G Protein–Coupled Bile Acid Receptors
by Brighton, Cheryl A and Rievaj, Juraj and Kuhre, Rune E and Glass, Leslie L and Schoonjans, Kristina and Holst, Jens J and Gribble, Fiona M and Reimann, Frank
Endocrinology, ISSN 0013-7227, 11/2015, Volume 156, Issue 11, pp. 3961 - 3970
Bile acids are well-recognized stimuli of glucagon-like peptide-1 (GLP-1) secretion. This action has been attributed to activation of the G protein–coupled... 
RESPONSES | CELLS | TGR5 | GASTRIC BYPASS-SURGERY | ACTIVATION | GLUCAGON-LIKE PEPTIDE-1 | GLUCOSE-METABOLISM | TOLERANCE | MOUSE | ENDOCRINOLOGY & METABOLISM | SECRETION | Bile Acids and Salts - pharmacology | Intracellular Space - drug effects | Glucagon-Like Peptide 1 - metabolism | Rats, Wistar | Receptors, G-Protein-Coupled - metabolism | Calcium - metabolism | Tissue Culture Techniques | Cells, Cultured | Male | Mice, Transgenic | Glucagon-Like Peptide 1 - secretion | Mice, Knockout | Animals | Intestine, Small - drug effects | Intracellular Space - metabolism | Receptors, G-Protein-Coupled - genetics | Enteroendocrine Cells - metabolism | Intestine, Small - metabolism | Enteroendocrine Cells - drug effects | Taurodeoxycholic Acid - pharmacology | Cyclic AMP - metabolism | Taurolithocholic Acid - pharmacology | Microscopy, Fluorescence | Original Research
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5. Full Text NF-κB-Inducing Kinase (NIK) Mediates Skeletal Muscle Insulin Resistance: Blockade by Adiponectin
by Choudhary, Sanjeev and Sinha, Sandeep and Zhao, Yanhua and Banerjee, Srijita and Sathyanarayana, Padma and Shahani, Sadeka and Sherman, Vadim and Tilton, Ronald. G and Bajaj, Mandeep
Endocrinology, ISSN 0013-7227, 10/2011, Volume 152, Issue 10, pp. 3622 - 3627
Enhanced levels of nuclear factor (NF)-κB-inducing kinase (NIK), an upstream kinase in the NF-κB pathway, have been implicated in the pathogenesis of chronic... 
ACTIVATION | OBESITY | PROTEIN | INHIBITOR | ENDOCRINOLOGY & METABOLISM | Diabetes-Insulin-Glucagon-Gastrointestinal
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6. Full Text Integrated Regulation of Hepatic Metabolism by Fibroblast Growth Factor 21 (FGF21) in Vivo
by Fisher, ffolliott M and Estall, Jennifer L and Adams, Andrew C and Antonellis, Patrick J and Bina, Holly A and Flier, Jeffrey S and Kharitonenkov, Alexei and Spiegelman, Bruce M and Maratos-Flier, Eleftheria
Endocrinology, ISSN 0013-7227, 08/2011, Volume 152, Issue 8, pp. 2996 - 3004
Fibroblast growth factor (FGF21) plays an important role in regulating hepatic oxidation of fatty acids and gluconeogenesis in response to fasting and during... 
BETA-KLOTHO | PPAR-ALPHA | LIPID-METABOLISM | FIBROBLAST-GROWTH-FACTOR-21 | THYROID-HORMONE | PGC-1-ALPHA | ENDOCRINOLOGY & METABOLISM | STATE | ENERGY-METABOLISM | INSULIN SENSITIVITY | EXPRESSION | Humans | Liver - metabolism | Mice, Inbred C57BL | Male | Forkhead Transcription Factors - physiology | Extracellular Signal-Regulated MAP Kinases - metabolism | Organ Specificity | MAP Kinase Signaling System | Trans-Activators - physiology | Animals | Membrane Proteins - physiology | PPAR alpha - physiology | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Trans-Activators - genetics | Forkhead Box Protein O1 | Mice | Transcription Factors | Fibroblast Growth Factors - physiology | Gluconeogenesis | Diabetes-Insulin-Glucagon-Gastrointestinal
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7. Full Text Glutamine Triggers and Potentiates Glucagon-Like Peptide-1 Secretion by Raising Cytosolic Ca2+ and cAMP
by Tolhurst, Gwen and Zheng, Yue and Parker, Helen E and Habib, Abdella M and Reimann, Frank and Gribble, Fiona M
Endocrinology, ISSN 0013-7227, 02/2011, Volume 152, Issue 2, pp. 405 - 413
The effects of chemical (DPP-4) inhibition and genetic reduction of DPP-4 activity on bone quality were studied in wild-type and ovariectomized mice.... 
SYSTEM | INSULIN | TRANSPORT | CELL-LINE | ENDOCRINOLOGY & METABOLISM | Glucagon-Like Peptide 1 - metabolism | Oligonucleotide Array Sequence Analysis | Calcium - metabolism | Cells, Cultured | Signal Transduction - genetics | Glucagon-Like Peptide 1 - secretion | Animals | Flow Cytometry | Signal Transduction - drug effects | Fluorescence Resonance Energy Transfer | Mice | Glutamine - pharmacology | Cyclic AMP - metabolism | Diabetes-Insulin-Glucagon-Gastrointestinal
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8. Full Text Functional Role of Serotonin in Insulin Secretion in a Diet-Induced Insulin-Resistant State
by Kim, Kyuho and Oh, Chang-Myung and Ohara-Imaizumi, Mica and Park, Sangkyu and Namkung, Jun and Yadav, Vijay K and Tamarina, Natalia A and Roe, Michael W and Philipson, Louis H and Karsenty, Gerard and Nagamatsu, Shinya and German, Michael S and Kim, Hail
Endocrinology, ISSN 0013-7227, 02/2015, Volume 156, Issue 2, pp. 444 - 452
The physiological role of serotonin, or 5-hydroxytryptamine (5-HT), in pancreatic β-cell function was previously elucidated using a pregnant mouse model.... 
BETA-CELL GROWTH | ISLETS | MOUSE | MASS | ENDOCRINOLOGY & METABOLISM | DETERMINANT | RATS | RECEPTOR | MECHANISMS | SUBSET | Insulin-Secreting Cells - physiology | Serotonin - physiology | Insulin Resistance | Male | Receptors, Serotonin - genetics | Receptors, Serotonin - metabolism | Mice, Knockout | Tryptophan Hydroxylase - genetics | Insulin - metabolism | Animals | Diet, High-Fat | Insulin Secretion | Tryptophan Hydroxylase - metabolism | Diabetes-Insulin-Glucagon-Gastrointestinal
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9. Full Text Cellular Mechanisms by Which FGF21 Improves Insulin Sensitivity in Male Mice
by Camporez, João Paulo G and Jornayvaz, François R and Petersen, Max C and Pesta, Dominik and Guigni, Blas A and Serr, Julie and Zhang, Dongyan and Kahn, Mario and Samuel, Varman T and Jurczak, Michael J and Shulman, Gerald I
Endocrinology, ISSN 0013-7227, 09/2013, Volume 154, Issue 9, pp. 3099 - 3109
Fibroblast growth factor 21 (FGF21) is a potent regulator of glucose and lipid metabolism and is currently being pursued as a therapeutic agent for insulin... 
INDUCED HEPATIC STEATOSIS | GLUCOSE-HOMEOSTASIS | INCREASED EXPRESSION | METABOLISM | FATTY LIVER-DISEASE | INCREASES ENERGY-EXPENDITURE | MITOCHONDRIAL-FUNCTION | ENDOCRINOLOGY & METABOLISM | RESISTANCE | MUSCLE | GROWTH-FACTOR 21 | Glucose Intolerance - metabolism | Recombinant Proteins - therapeutic use | Adipose Tissue, Brown - surgery | Liver - pathology | Humans | Protein Kinase C-theta | Diet, High-Fat - adverse effects | Drug Implants | Male | Muscle, Skeletal - metabolism | Glucose Intolerance - pathology | Fibroblast Growth Factors - metabolism | Glucose Intolerance - drug therapy | Lipectomy | Liver - drug effects | Fibroblast Growth Factors - administration & dosage | Glucose Intolerance - etiology | Isoenzymes - metabolism | Protein Kinase C - metabolism | Muscle, Skeletal - drug effects | Fibroblast Growth Factors - therapeutic use | Recombinant Proteins - metabolism | Liver - metabolism | Mice, Inbred C57BL | Cells, Cultured | Insulin Resistance | Recombinant Proteins - administration & dosage | Infusions, Subcutaneous | Animals | Protein Kinase C-epsilon - metabolism | Lipid Metabolism - drug effects | Adipose Tissue, Brown - drug effects | Adipose Tissue, Brown - metabolism | Mice | Muscle, Skeletal - pathology | Energy Metabolism - drug effects | Diabetes-Insulin-Glucagon-Gastrointestinal
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10. Full Text Cellular Mechanism by Which Estradiol Protects Female Ovariectomized Mice From High-Fat Diet-Induced Hepatic and Muscle Insulin Resistance
by Camporez, João Paulo G and Jornayvaz, François R and Lee, Hui-Young and Kanda, Shoichi and Guigni, Blas A and Kahn, Mario and Samuel, Varman T and Carvalho, Carla R.O and Petersen, Kitt Falk and Jurczak, Michael J and Shulman, Gerald I
Endocrinology, ISSN 0013-7227, 03/2013, Volume 154, Issue 3, pp. 1021 - 1028
Estrogen replacement therapy reduces the incidence of type 2 diabetes in postmenopausal women; however, the mechanism is unknown. Therefore, the aim of this... 
ACTIVATION | HEALTH | PROGESTERONE | ESTROGEN SULFOTRANSFERASE | SEX | ENDOCRINOLOGY & METABOLISM | Estrogen Replacement Therapy | Humans | Diet, High-Fat - adverse effects | Muscle, Skeletal - metabolism | Diabetes Mellitus, Type 2 - metabolism | Liver - drug effects | Insulin Resistance - physiology | Protein Kinase C - metabolism | Muscle, Skeletal - drug effects | Female | Models, Animal | Homeostasis - drug effects | Estradiol - pharmacology | Estradiol - metabolism | Ovariectomy | Liver - metabolism | Diabetes Mellitus, Type 2 - prevention & control | Estradiol - deficiency | Eating - drug effects | Animals | Menopause - metabolism | Lipid Metabolism - drug effects | Glucose - metabolism | Mice | Energy Metabolism - drug effects | Diabetes-Insulin-Glucagon-Gastrointestinal
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11. Full Text Calcium Efflux From the Endoplasmic Reticulum Leads to β-Cell Death
by Hara, Takashi and Mahadevan, Jana and Kanekura, Kohsuke and Hara, Mariko and Lu, Simin and Urano, Fumihiko
Endocrinology, ISSN 0013-7227, 03/2014, Volume 155, Issue 3, pp. 758 - 768
It has been established that intracellular calcium homeostasis is critical for survival and function of pancreatic β-cells. However, the role of endoplasmic... 
DIABETES-MELLITUS | APOPTOSIS | WFS1 GENE | ACTIVATION | UBIQUITOUS CALPAINS PROMOTE | INS GENE | ER STRESS | WOLFRAM-SYNDROME | ENDOCRINOLOGY & METABOLISM | THIOREDOXIN-INTERACTING PROTEIN | FATTY-ACIDS | Sarcoplasmic Reticulum Calcium-Transporting ATPases - metabolism | Calcium - metabolism | Cell Separation | Humans | Cells, Cultured | Endoplasmic Reticulum - metabolism | Homeostasis | Male | Plasmids - metabolism | Animals | Flow Cytometry | Inositol 1,4,5-Trisphosphate Receptors - metabolism | Cell Death | HEK293 Cells | Fluorescence Resonance Energy Transfer | Mice | Insulin-Secreting Cells - pathology | Fatty Acids - metabolism | Real-Time Polymerase Chain Reaction | Diabetes-Insulin-Glucagon-Gastrointestinal
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12. Full Text Leptin Activates a Novel CNS Mechanism for Insulin-Independent Normalization of Severe Diabetic Hyperglycemia
by German, Jonathan P and Thaler, Joshua P and Wisse, Brent E and Oh-I, Shinsuke and Sarruf, David A and Matsen, Miles E and Fischer, Jonathan D and Taborsky, Gerald J and Schwartz, Michael W and Morton, Gregory J
Endocrinology, ISSN 0013-7227, 02/2011, Volume 152, Issue 2, pp. 394 - 404
Leptin action in the brain normalizes diabetic hyperglycemia by suppressing hepatic glucose production while increasing tissue glucose uptake despite severe... 
PROTEIN-2 MESSENGER-RNA | HYPERPHAGIA | FOOD-INTAKE | PROOPIOMELANOCORTIN NEURONS | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | RATS | RESISTANCE | SENSITIVITY | PERIPHERAL-TISSUES | GLUCOSE-PRODUCTION | Insulin - pharmacology | Diabetes Mellitus, Experimental - drug therapy | Glucose Tolerance Test | Rats, Wistar | Rats | Male | Reverse Transcriptase Polymerase Chain Reaction | Glucagon - blood | Hyperglycemia - drug therapy | Blood Glucose - drug effects | Brain - drug effects | Brain - metabolism | Diabetes Mellitus, Experimental - blood | Animals | Hyperglycemia - blood | Body Composition - drug effects | Leptin - pharmacology | Corticosterone - blood | Diabetes-Insulin-Glucagon-Gastrointestinal
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13. Full Text Hepatic Suppression of Foxo1 and Foxo3 Causes Hypoglycemia and Hyperlipidemia in Mice
by Zhang, Kebin and Li, Ling and Qi, Yajuan and Zhu, Xiaoping and Gan, Boyi and DePinho, Ronald A and Averitt, Travis and Guo, Shaodong
Endocrinology, ISSN 0013-7227, 02/2012, Volume 153, Issue 2, pp. 631 - 646
Dysregulation of blood glucose and triglycerides are the major characteristics of type 2 diabetes mellitus. We sought to identify the mechanisms regulating... 
REGULATES LIPID-METABOLISM | FORKHEAD TRANSCRIPTION FACTOR | PHOSPHOENOLPYRUVATE CARBOXYKINASE | INSULIN-RESPONSE SEQUENCE | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | FACTOR-BINDING PROTEIN-1 | KINASE-B | NUTRIENT HOMEOSTASIS | SIGNALING CASCADE | GLUCOSE-PRODUCTION | Hyperlipidemias - metabolism | Liver - metabolism | Gene Expression Regulation | Homeostasis | Forkhead Transcription Factors - genetics | Hypoglycemia - metabolism | Mice, Knockout | Gluconeogenesis - physiology | Animals | Forkhead Transcription Factors - metabolism | Glucose - metabolism | Mice, Inbred NOD | Forkhead Box Protein O1 | Mice | Blood Glucose - metabolism | Forkhead Box Protein O3 | Lipid Metabolism - physiology | Diabetes-Insulin-Glucagon-Gastrointestinal
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14. Full Text PPARγ-Independent Increase in Glucose Uptake and Adiponectin Abundance in Fat Cells
by Dubuisson, Olga and Dhurandhar, Emily J and Krishnapuram, Rashmi and Kirk-Ballard, Heather and Gupta, Alok K and Hegde, Vijay and Floyd, Elizabeth and Gimble, Jeffrey M and Dhurandhar, Nikhil V
Endocrinology, ISSN 0013-7227, 10/2011, Volume 152, Issue 10, pp. 3648 - 3660
Although thiazolidinediones (TZD) effectively improve hyperglycemia and increase adiponectin, a proinsulin-sensitizing adipokine, they also increase... 
3T3-L1 ADIPOCYTES | LIPID-ACCUMULATION | IN-VITRO | HUMAN ADENOVIRUS TYPE-36 | ENDOCRINOLOGY & METABOLISM | ACTIVATED-RECEPTOR-GAMMA | MICE | DIFFERENTIATION | INSULIN SENSITIVITY | AGONISTS | ADIPOSE-TISSUE | Diabetes-Insulin-Glucagon-Gastrointestinal
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15. Full Text Liver-Enriched Transcription Factor CREBH Interacts With Peroxisome Proliferator-Activated Receptor α to Regulate Metabolic Hormone FGF21
by Kim, Hyunbae and Mendez, Roberto and Zheng, Ze and Chang, Lin and Cai, Juan and Zhang, Ren and Zhang, Kezhong
Endocrinology, ISSN 0013-7227, 03/2014, Volume 155, Issue 3, pp. 769 - 782
Lipid metabolism is tightly regulated by nuclear receptors, transcription factors, and cellular enzymes. In this study, we demonstrated that the liver-enriched... 
PPAR-ALPHA | OBESITY | FIBROBLAST-GROWTH-FACTOR-21 | DISEASE | ENDOCRINOLOGY & METABOLISM | ELEMENT-BINDING PROTEIN | MICE | STEATOHEPATITIS | STRESS | IDENTIFICATION | GROWTH-FACTOR 21 | Promoter Regions, Genetic | Liver - metabolism | Gene Expression Regulation | Homeostasis | Molecular Sequence Data | Recombinant Proteins - chemistry | Male | Hepatocytes - metabolism | Sequence Homology, Nucleic Acid | Amino Acid Motifs | Mice, Knockout | Triglycerides - metabolism | Cyclic AMP Response Element-Binding Protein - genetics | Fibroblast Growth Factors - metabolism | Lipids - chemistry | Animals | Base Sequence | Cyclic AMP Response Element-Binding Protein - metabolism | Protein Binding | Mice | PPAR alpha - metabolism | Fatty Acids - metabolism | Diabetes-Insulin-Glucagon-Gastrointestinal
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16. Full Text Resveratrol Attenuates Intermittent Hypoxia-Induced Macrophage Migration to Visceral White Adipose Tissue and Insulin Resistance in Male Mice
by Carreras, Alba and Zhang, Shelley X. L and Almendros, Isaac and Wang, Yang and Peris, Eduard and Qiao, Zhuanhong and Gozal, David
Endocrinology, ISSN 0013-7227, 02/2015, Volume 156, Issue 2, pp. 437 - 443
Chronic intermittent hypoxia during sleep (IH), as occurs in sleep apnea, promotes systemic insulin resistance. Resveratrol (Resv) has been reported to... 
OBSTRUCTIVE SLEEP-APNEA | MURINE MODEL | SPATIAL-LEARNING DEFICITS | INFLAMMATION | MITOCHONDRIAL-FUNCTION | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | NITRIC-OXIDE | POSITIVE AIRWAY PRESSURE | DIET-INDUCED OBESITY | HUMAN ADIPOCYTES | Intra-Abdominal Fat - immunology | Eating | Mice, Inbred C57BL | Insulin Resistance | Male | Hypoxia - immunology | Random Allocation | Stilbenes - pharmacology | Insulin - blood | Animals | Leptin - blood | Macrophages - drug effects | Drug Evaluation, Preclinical | Weight Gain | Anti-Obesity Agents - pharmacology | Diabetes-Insulin-Glucagon-Gastrointestinal
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17. Full Text Impact of Diet-Induced Obesity on Intestinal Stem Cells: Hyperproliferation but Impaired Intrinsic Function That Requires Insulin/IGF1
by Mah, Amanda T and Van Landeghem, Laurianne and Gavin, Hannah E and Magness, Scott T and Lund, P. Kay
Endocrinology, ISSN 0013-7227, 09/2014, Volume 155, Issue 9, pp. 3302 - 3314
Nutrient intake regulates intestinal epithelial mass and crypt proliferation. Recent findings in model organisms and rodents indicate nutrient restriction... 
HIGH-FAT DIET | GLUCAGON-LIKE PEPTIDE-2 | ENTEROENDOCRINE CELLS | DISTINCT | ENDOCRINOLOGY & METABOLISM | RATS | MICE | PROLIFERATION | BETA-CATENIN | ENTERAL NUTRIENTS | GROWTH-FACTOR-I | Cell Proliferation | Signal Transduction | Humans | Diet, High-Fat - adverse effects | Male | Mice, Transgenic | Obesity - physiopathology | Intestines - metabolism | Stem Cells - cytology | Stem Cells - metabolism | Obesity - genetics | Obesity - metabolism | Insulin - metabolism | Animals | Female | Mice | Insulin-Like Growth Factor I - metabolism | Intestines - cytology | Diabetes-Insulin-Glucagon-Gastrointestinal
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18. Full Text Mechanisms of Estradiol-Induced Insulin Secretion by the G Protein-Coupled Estrogen Receptor GPR30/GPER in Pancreatic β-Cells
by Sharma, Geetanjali and Prossnitz, Eric R
Endocrinology, ISSN 0013-7227, 08/2011, Volume 152, Issue 8, pp. 3030 - 3039
Sexual dimorphism and supplementation studies suggest an important role for estrogens in the amelioration of glucose intolerance and diabetes. Because little... 
BREAST-CANCER | GROWTH-FACTOR RECEPTOR | PLASMA-MEMBRANE RECEPTOR | HUMAN ISLETS | PHOSPHATIDYLINOSITOL 3-KINASE | IN-VIVO | FEMALE MICE | ENDOCRINOLOGY & METABOLISM | G-PROTEIN-COUPLED-RECEPTOR-30 GPR30 | 17-BETA-ESTRADIOL | ER-ALPHA | Amino Acid Sequence | Receptors, Estrogen | Calcium - metabolism | Mice, Inbred C57BL | Cercopithecus aethiops | Molecular Sequence Data | Phosphatidylinositol 3-Kinases - metabolism | Cyclopentanes - pharmacology | Extracellular Signal-Regulated MAP Kinases - metabolism | Quinolines - pharmacology | Insulin - metabolism | Insulin-Secreting Cells - metabolism | Animals | Insulin-Secreting Cells - drug effects | Cell Line, Tumor | Female | Mice | COS Cells | Insulin Secretion | Estradiol - pharmacology | Receptors, G-Protein-Coupled - physiology | Diabetes-Insulin-Glucagon-Gastrointestinal
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19. Full Text Hyperinsulinemia Induces Insulin Resistance in Dorsal Root Ganglion Neurons
by Kim, Bhumsoo and McLean, Lisa L and Philip, Stephen S and Feldman, Eva L
Endocrinology, ISSN 0013-7227, 10/2011, Volume 152, Issue 10, pp. 3638 - 3647
Insulin resistance (IR) is the major feature of metabolic syndrome, including type 2 diabetes. IR studies are mainly focused on peripheral tissues, such as... 
OXIDATIVE STRESS | SIGNALING PATHWAYS | METABOLIC SYNDROME | PHOSPHATIDYLINOSITOL 3-KINASE | PROTEIN EXPRESSION | ENDOCRINOLOGY & METABOLISM | MITOCHONDRIAL DYSFUNCTION | GROWTH-FACTOR | DIABETIC-NEUROPATHY | HUMAN SKELETAL-MUSCLE | RECEPTOR SUBSTRATE-1 | Hyperinsulinism - metabolism | Phosphorylation | Animals | Mice, Inbred C57BL | Insulin Resistance | Rats | Mice | Extracellular Signal-Regulated MAP Kinases - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Rats, Sprague-Dawley | Ganglia, Spinal - metabolism | 500 | Diabetes-Insulin-Glucagon-Gastrointestinal | 300
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20. Full Text Targeted Deletion of Adipocytes by Apoptosis Leads to Adipose Tissue Recruitment of Alternatively Activated M2 Macrophages
by Fischer-Posovszky, Pamela and Wang, Qiong A and Asterholm, Ingrid Wernstedt and Rutkowski, Joseph M and Scherer, Philipp E
Endocrinology, ISSN 0013-7227, 08/2011, Volume 152, Issue 8, pp. 3074 - 3081
Obesity is frequently associated with an infiltration of macrophages into adipose tissue. Adipocyte dysfunction causes a phenotypic switch of macrophages from... 
CELLS | INFLAMMATION | ENDOCRINOLOGY & METABOLISM | FAT | MICE | DEATH | DYSFUNCTION | DIET-INDUCED OBESITY | POLARIZATION | EXPRESSION | INDUCED INSULIN-RESISTANCE | Macrophages - physiology | Antigens, Differentiation - analysis | Cell Polarity | Adipose Tissue - physiology | Receptors, Cell Surface - analysis | Asialoglycoproteins - analysis | Male | CD11c Antigen - analysis | Adipocytes - physiology | Inflammation - etiology | Membrane Proteins - analysis | Macrophage Activation | Animals | CD11c Antigen - genetics | Lectins, C-Type - analysis | Mannose-Binding Lectins - analysis | Antigens, Differentiation - genetics | Mice | Apoptosis | Diabetes-Insulin-Glucagon-Gastrointestinal
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