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Journal Article
Journal Article
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 03/2012, Volume 23, Issue 3, pp. 458 - 469
Journal Article
Diabetes, ISSN 0012-1797, 11/2011, Volume 60, Issue 11, pp. 3055 - 3066
OBJECTIVE-To determine whether dietary compounds targeting NFE2-related factor 2 (Nrf2) activation can be used to attenuate renal damage and preserve renal... 
PERFORMANCE LIQUID-CHROMATOGRAPHY | GROWTH-FACTOR-BETA | OXIDATIVE STRESS | TGF-BETA | GLOMERULAR HYPERTROPHY | CELLS IN-VITRO | BARDOXOLONE METHYL | KIDNEY-FUNCTION | ENDOCRINOLOGY & METABOLISM | SULFORAPHANE PROTECTS | HIGH-DOSE THIAMINE | Acrolein - analogs & derivatives | Reactive Oxygen Species - metabolism | Kidney - pathology | Humans | Transforming Growth Factor beta1 - metabolism | NF-E2-Related Factor 2 - agonists | Mesangial Cells - drug effects | Dose-Response Relationship, Drug | Diabetic Nephropathies - physiopathology | RNA Interference | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Thiocyanates - pharmacology | NF-E2-Related Factor 2 - genetics | Thiocyanates - administration & dosage | Diabetic Nephropathies - prevention & control | Isothiocyanates | Extracellular Matrix Proteins - metabolism | Kidney - physiopathology | Acrolein - pharmacology | Thiocyanates - therapeutic use | Diabetic Nephropathies - pathology | Kidney - drug effects | Acrolein - administration & dosage | Diabetic Nephropathies - metabolism | Mice, Inbred C57BL | Cells, Cultured | Mesangial Cells - metabolism | Random Allocation | Mice, Knockout | Animals | NF-E2-Related Factor 2 - metabolism | Mesangial Cells - pathology | Acrolein - therapeutic use | Cell Proliferation - drug effects | Mice | RNA, Small Interfering | Oxidative Stress - drug effects | Care and treatment | Streptozocin | Diabetic nephropathies | Weight loss | Development and progression | Research | Health aspects | Risk factors | Index Medicus | Abridged Index Medicus | Pharmacology and Therapeutics
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 11/2016, Volume 126, Issue 11, pp. 4205 - 4218
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, pp. e54442 - e54442
Sodium/glucose cotransporter 2 (SGLT2) inhibitors are oral hypoglycemic agents used to treat patients with diabetes mellitus. SGLT2 inhibitors block... 
MATRIX | STIMULATION | MULTIDISCIPLINARY SCIENCES | DISEASE | HIGH GLUCOSE | GENE-EXPRESSION | MESANGIAL CELLS | PPAR-GAMMA AGONISTS | MELLITUS | TRANSFORMING GROWTH FACTOR-BETA | Diabetes Mellitus - pathology | Epithelial Cells - metabolism | Gene Expression - drug effects | Diabetes Mellitus - genetics | Transcription Factor AP-1 - genetics | Epithelial Cells - drug effects | Humans | Diabetic Nephropathies - drug therapy | NF-kappa B - metabolism | Smad3 Protein - metabolism | Transcription Factor AP-1 - metabolism | Sodium-Glucose Transporter 1 - genetics | Smad3 Protein - genetics | Sodium-Glucose Transporter 1 - metabolism | Phosphorylation - drug effects | Interleukin-6 - metabolism | Transforming Growth Factor beta1 - pharmacology | Sodium-Glucose Transporter 2 - genetics | Collagen Type IV - metabolism | Sodium-Glucose Transporter 1 - antagonists & inhibitors | Promoter Regions, Genetic | Diabetic Nephropathies - pathology | Glucosides - pharmacology | Kidney Tubules, Proximal - pathology | Interleukin-6 - genetics | Sodium-Glucose Transporter 2 - metabolism | Diabetic Nephropathies - metabolism | Diabetes Mellitus - drug therapy | Diabetes Mellitus - metabolism | Toll-Like Receptor 4 - genetics | Diabetic Nephropathies - genetics | Epithelial Cells - pathology | Glucose - pharmacology | Toll-Like Receptor 4 - metabolism | Sodium-Glucose Transporter 2 - antagonists & inhibitors | Hypoglycemic Agents - pharmacology | NF-kappa B - genetics | Kidney Tubules, Proximal - metabolism | Collagen Type IV - genetics | Protein Binding | Benzhydryl Compounds - pharmacology | Kidney Tubules, Proximal - drug effects | Physiological aspects | Care and treatment | Genetic aspects | Research | Transforming growth factors | Diabetic nephropathies | Chromatin | Immunoprecipitation | Transforming growth factor-b | Interleukin | Clinical trials | Systematic review | Smad3 protein | Glucose | Kinases | Interleukin 6 | Proteins | Hyperglycemia | Rodents | Toll-like receptors | Collagen (type IV) | Hypoglycemic agents | Inhibition | Growth factors | Deoxyribonucleic acid--DNA | Binding | Glucose transporter | Medical research | NF-κB protein | Secretion | Diabetes mellitus | Markers | Activator protein 1 | Blocking | Reabsorption | Inflammation | Gene expression | Glucose transport | Immune systems | Medicine | High mobility group proteins | Hospitals | Inhibitors | Nephropathy | Sodium | Fibrosis | Kidney diseases | Diabetes | Transporter | Adenosine triphosphatase | Kidney transplantation | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Diabetes, ISSN 0012-1797, 03/2016, Volume 65, Issue 3, pp. 755 - 767
Overcoming refractory massive proteinuria remains a clinical and research issue in diabetic nephropathy. This study was designed to investigate the... 
MAINTENANCE | LYSOSOMES | NUMBER | MICROALBUMINURIA | INCREASE | ENDOCRINOLOGY & METABOLISM | TUBULE | MICE | DIFFERENTIATION | MTOR | REMISSION | Kidney - pathology | Microtubule-Associated Proteins - genetics | Diabetic Nephropathies - etiology | Humans | Middle Aged | Rats, Long-Evans | Male | Intracellular Signaling Peptides and Proteins - metabolism | Diabetes Mellitus, Type 2 - metabolism | Proteinuria - pathology | Autophagy | Young Adult | Kidney - metabolism | Lysosomes - metabolism | Diet, High-Fat | Adult | Female | Lysosomes - pathology | Diabetes Mellitus, Experimental - complications | Membrane Proteins - metabolism | Microfilament Proteins - metabolism | RNA-Binding Proteins - blood | Diabetes Mellitus, Experimental - metabolism | Diabetes Mellitus, Type 2 - complications | Intravital Microscopy | Proteinuria - etiology | Severity of Illness Index | Cell Line | Microscopy, Electron, Transmission | Diabetic Nephropathies - pathology | Microscopy, Electron, Scanning | Podocytes - metabolism | Diabetic Nephropathies - metabolism | Mice, Inbred C57BL | Proteinuria - metabolism | Rats | Mice, Transgenic | Blotting, Western | Mice, Knockout | Autophagy-Related Protein 7 | Animals | Autophagy-Related Protein 5 | Diabetes Mellitus, Experimental - pathology | Aged | Mice | Diabetes Mellitus, Type 2 - pathology | Apoptosis | Care and treatment | Diabetic nephropathies | Homeostasis | Influence | Dosage and administration | Research | Insulin | Proteinuria | Proteins | Diabetic neuropathy | Diabetes | Pathogenesis | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article