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PLoS ONE, ISSN 1932-6203, 06/2017, Volume 12, Issue 6, pp. e0178658 - e0178658
Background Diabetic retinopathy is characterized by defects in the retinal neurovascular unit. The underlying mechanisms of impairment including reactive... 
COMPLEMENT | RAT | MULTIDISCIPLINARY SCIENCES | ANIMAL-MODELS | COMPLICATIONS | EXPRESSION | DAMAGE | Retina - metabolism | Complement Activation | Rats, Wistar | Diabetes Mellitus, Type 2 - genetics | Diabetes Mellitus, Experimental - genetics | Hyperglycemia - complications | Male | Gene Expression Profiling | Diabetes Mellitus, Type 2 - metabolism | Hyperglycemia - genetics | Rats, Mutant Strains | Hyperinsulinism - genetics | Eye Proteins - genetics | Diabetes Mellitus, Experimental - metabolism | Hyperinsulinism - metabolism | Hyperinsulinism - complications | Signal Transduction | Acute-Phase Proteins | Gene Expression Regulation | Insulin Resistance | Diabetic Retinopathy - metabolism | Diabetic Retinopathy - genetics | Hyperglycemia - metabolism | Oncostatin M - biosynthesis | Animals | Diabetes Mellitus, Type 2 - physiopathology | Oncostatin M - genetics | Eye Proteins - biosynthesis | Diabetic retinopathy | Insulin resistance | Genetic aspects | Drug therapy | Hyperinsulinemia | Regulators | Animal models | Retinopathy | Transcription | Interleukin | Impairment | Retina | Activation | Complement | Glucose | Defects | Interleukin 6 | Genotype & phenotype | Signal transduction | Hyperglycemia | Pathways | Technology | Rodents | Bioinformatics | Growth factors | Age | Obesity | Patterning | Phase transformations | Mortality | Diabetes mellitus | Rats | Injection | Group dynamics | Metabolism | Gene expression | Clustering | Insulin | Intermediates | Polymerase chain reaction | Signaling | Complement activation | Interferon | Diabetes | Arrays | Index Medicus
Journal Article
Diabetes, ISSN 0012-1797, 02/2011, Volume 60, Issue 2, pp. 614 - 624
OBJECTIVE-Arachidonic acid is metabolized by 12-lipoxygenase (12-LOX) to 12-hydroxyeicosatetraenoic acid (12-HETE) and has an important role in the regulation... 
EPITHELIUM-DERIVED FACTOR | NAD(P)H OXIDASE | PROSTATE-CANCER CELLS | MOUSE MODEL | ENDOCRINOLOGY & METABOLISM | SMOOTH-MUSCLE-CELLS | ANGIOTENSIN-II | TUMOR ANGIOGENESIS | LEUKOCYTE-TYPE | ENDOTHELIAL GROWTH-FACTOR | 12/15-LIPOXYGENASE | Immunohistochemistry | Arachidonate 12-Lipoxygenase - metabolism | Humans | Nerve Growth Factors - metabolism | Retinal Neovascularization - metabolism | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Vitreous Body - metabolism | Mass Spectrometry | Retinal Neovascularization - genetics | Eye Proteins - genetics | Serpins - genetics | Enzyme-Linked Immunosorbent Assay | Retinal Vessels - metabolism | Serpins - metabolism | Flavanones - pharmacology | Enzyme Inhibitors - pharmacology | Ischemia - metabolism | Retinal Vessels - drug effects | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Diabetic Retinopathy - metabolism | Diabetic Retinopathy - genetics | Hydroxyeicosatetraenoic Acids - metabolism | Animals | Analysis of Variance | Eye Proteins - metabolism | Nerve Growth Factors - genetics | Mice | Diabetic retinopathy | Physiological aspects | Development and progression | Genetic aspects | Research | Neovascularization | Vascular endothelial growth factor | Risk factors | Index Medicus | Abridged Index Medicus | Complications
Journal Article
Diabetes, ISSN 0012-1797, 04/2011, Volume 60, Issue 4, pp. 1314 - 1323
Journal Article
Medicine, ISSN 0025-7974, 03/2019, Volume 98, Issue 11, pp. e14878 - e14878
Journal Article
Journal Article
Diabetes, ISSN 0012-1797, 04/2011, Volume 60, Issue 4, pp. 1304 - 1313
OBJECTIVE-To investigate the role of epigenetic regulation of the manganese superoxide dismutase gene (sod2) in the development of diabetic retinopathy and the... 
OXIDATIVE STRESS | CAPILLARY CELL-DEATH | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE | IN-VIVO | EXPERIMENTAL GALACTOSEMIA | ENDOCRINOLOGY & METABOLISM | HIGH GLUCOSE | RATS | MATRIX METALLOPROTEINASE-2 | METABOLIC MEMORY PHENOMENON | HISTONE | Protein Binding - genetics | Retina - metabolism | Superoxide Dismutase - genetics | Immunoprecipitation | Rats, Wistar | Male | NF-kappa B p50 Subunit - genetics | Promoter Regions, Genetic - genetics | Transcription Factor RelA - genetics | Diabetic Retinopathy - physiopathology | Chromatin Immunoprecipitation | Hyperglycemia - physiopathology | NF-kappa B p50 Subunit - metabolism | Endothelial Cells - metabolism | Rats | Random Allocation | Blotting, Western | Diabetic Retinopathy - metabolism | Diabetic Retinopathy - genetics | Hyperglycemia - metabolism | Animals | Diabetic Retinopathy - enzymology | Transcription Factor RelA - metabolism | Epigenesis, Genetic - genetics | Retina - pathology | Protein Binding - physiology | Diabetic retinopathy | Epigenetic inheritance | Physiological aspects | Development and progression | Superoxide dismutase | Genetic aspects | Research | Risk factors | Index Medicus | Abridged Index Medicus | Chromatin | Retinopathy | Diabetes mellitus | Memory | Retina | siRNA | Gene expression | Guanylate cyclase | Endothelial cells | Promoters | epigenetics | Galactosemia | Diets | Histone H4 | Enhancers | Hyperglycemia | Mitochondria | NF- Kappa B protein | Lysine | Galactose | Histone H3 | Manganese | Complications
Journal Article
Journal Article